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SER
Upturn stock rating

Serina Therapeutics Inc (SER)

Upturn stock rating
$5.15
Last Close (24-hour delay)
upturn advisory
PASS
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  • SELL Advisory (Profit)​
  • SELL Advisory (Loss)​
  • Profit
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  • Pass (Skip investing)
Upturn Stock info Stock price based on last close
*as per simulation
(see disclosures)
Time period over
  • ALL
  • YEAR
  • MONTH
  • WEEK

Upturn Advisory Summary

10/15/2025: SER (1-star) is currently NOT-A-BUY. Pass it for now.

Upturn Star Rating

rating

Not Recommended Performance

These Stocks/ETFs, based on Upturn Advisory, consistently fall short of market performance, signaling caution before investing.

Number of Analysts

rating

1 Analysts rated it

Very few follow this stock; limited insights, higher-risk early investing.

1 Year Target Price $13

1 Year Target Price $13

Analysts Price Target For last 52 week
$13 Target price
52w Low $3.81
Current$5.15
52w High $8.05

Analysis of Past Performance

Type Stock
Historic Profit -58.81%
Avg. Invested days 23
Today’s Advisory PASS
Upturn Star Rating upturn star rating icon
Upturn Advisory Performance Upturn Advisory Performance 3.0
Stock Returns Performance Upturn Returns Performance 1.0
Upturn Profits based on simulation Profits based on simulation
Upturn Profits based on simulation Last Close 10/15/2025

Key Highlights

Company Size Small-Cap Stock
Market Capitalization 51.53M USD
Price to earnings Ratio -
1Y Target Price 13
Price to earnings Ratio -
1Y Target Price 13
Volume (30-day avg) 1
Beta -
52 Weeks Range 3.81 - 8.05
Updated Date 10/17/2025
52 Weeks Range 3.81 - 8.05
Updated Date 10/17/2025
Dividends yield (FY) -
Basic EPS (TTM) -0.92

Earnings Date

Report Date -
When -
Estimate -
Actual -

Profitability

Profit Margin -
Operating Margin (TTM) -4280.77%

Management Effectiveness

Return on Assets (TTM) -132.37%
Return on Equity (TTM) -485.36%

Valuation

Trailing PE -
Forward PE -
Enterprise Value 54404200
Price to Sales(TTM) 396.36
Enterprise Value 54404200
Price to Sales(TTM) 396.36
Enterprise Value to Revenue -
Enterprise Value to EBITDA 37.36
Shares Outstanding 10537181
Shares Floating 3271578
Shares Outstanding 10537181
Shares Floating 3271578
Percent Insiders 47.87
Percent Institutions 3.92

ai summary icon Upturn AI SWOT

Serina Therapeutics Inc

stock logo

Company Overview

overview logo History and Background

Serina Therapeutics Inc. is a clinical-stage biopharmaceutical company focused on developing innovative therapeutics utilizing its proprietary POZ Platform technology to address unmet medical needs in oncology, pain, and other areas. Founded to develop and commercialize POZ-modified therapeutics.

business area logo Core Business Areas

  • Oncology: Development of POZ-modified therapeutics for the treatment of various cancers, including solid tumors and hematological malignancies. Focus is on improving drug delivery and efficacy while reducing side effects.
  • Pain Management: Development of POZ-modified therapeutics for the treatment of chronic and acute pain conditions. Aim is to develop non-opioid pain management solutions with improved efficacy and safety profiles.
  • Neurology: Exploration of POZ Platform in neurological disorder such as Parkinson's disease and multiple sclerosis.

leadership logo Leadership and Structure

The company has a management team with expertise in drug development, clinical research, and commercialization. Specific leadership details and organizational structure are available on the company's website and SEC filings.

Top Products and Market Share

overview logo Key Offerings

  • ST-2462: A POZ-modified topoisomerase II inhibitor in Phase 1/2 clinical trials for solid tumors. Market share data is not yet available due to its early stage of development. Competitors include companies developing other topoisomerase II inhibitors.
  • ST-2464: A POZ-modified formulation for pain management. Preclinical development. Market share data is not yet available. Potential competitors are manufacturers of other pain medications (opioid and non-opioid) such as Pfizer, Teva.

Market Dynamics

industry overview logo Industry Overview

The biopharmaceutical industry is characterized by intense competition, rapid technological advancements, and stringent regulatory requirements. The market is driven by an aging population, increasing prevalence of chronic diseases, and growing demand for innovative therapies.

Positioning

Serina Therapeutics is positioned as a company developing novel therapeutics based on its POZ platform. Its competitive advantage lies in its proprietary technology, which aims to improve drug delivery and efficacy while reducing toxicity.

Total Addressable Market (TAM)

The TAM for oncology and pain management therapeutics is estimated to be in the billions of dollars. Serina Therapeutics is targeting specific sub-segments within these markets, aiming to capture a portion of the TAM through its innovative therapies.

Upturn SWOT Analysis

Strengths

  • Proprietary POZ Platform technology
  • Focus on unmet medical needs
  • Experienced management team
  • Pipeline of novel therapeutic candidates

Weaknesses

  • Early stage of development
  • Limited financial resources
  • Dependence on key personnel
  • No products currently on the market

Opportunities

  • Partnerships with larger pharmaceutical companies
  • Expansion of the POZ Platform to new therapeutic areas
  • Successful clinical trials and regulatory approvals
  • Growing demand for innovative therapies

Threats

  • Competition from established pharmaceutical companies
  • Failure to obtain regulatory approvals
  • Clinical trial failures
  • Patent disputes
  • Economic downturn

Competitors and Market Share

competitor logo Key Competitors

  • PFE
  • MRK
  • BMY

Competitive Landscape

Serina Therapeutics faces intense competition from larger, more established pharmaceutical companies with greater financial resources and broader pipelines. Its advantage lies in its innovative POZ Platform technology, but it must successfully navigate the regulatory and commercialization challenges.

Growth Trajectory and Initiatives

Historical Growth: Historical growth has been limited to the expansion of its pipeline and advancements in its POZ Platform technology.

Future Projections: Future growth is dependent on successful clinical trials, regulatory approvals, and commercialization of its therapeutic candidates. Analyst estimates are not readily available for smaller, development-stage companies.

Recent Initiatives: Recent initiatives include advancing its clinical programs, securing funding, and exploring potential partnerships.

Summary

Serina Therapeutics is a development-stage company with a promising POZ Platform technology. Its success hinges on advancing its clinical programs and securing regulatory approvals. The company faces significant competition and financial challenges, but its innovative technology offers potential for growth. Early indications are promising, yet the company needs to mitigate risk to stay afloat and become more profitable.

Peer Comparison

Sources and Disclaimers

Data Sources:

  • Company website
  • SEC filings
  • Industry reports
  • Press releases

Disclaimers:

This analysis is for informational purposes only and does not constitute investment advice. The data and analysis are based on publicly available information and are subject to change. Investing in development-stage companies carries significant risk.

Upturn AI Summarization AI Summarization is directionally correct and might not be accurate.

Upturn AI Summarization Summarized information shown could be a few years old and not current.

Upturn AI Summarization Fundamental Rating based on AI could be based on old data.

Upturn AI Summarization AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.

About Serina Therapeutics Inc

Exchange NYSE MKT
Headquaters Huntsville, AL, United States
IPO Launch date 2018-11-29
CEO & Director Mr. Steven A. Ledger
Sector Healthcare
Industry Biotechnology
Full time employees 12
Full time employees 12

Serina Therapeutics, Inc., a biotechnology company, develops drugs to treat neurological diseases and pain. Its lead product candidate is SER 252 (POZ-apomorphine), a POZ conjugate for the treatment of advanced Parkinson's disease that is in preclinical stage development; and POZ-lipids, a non-immunogenic alternative to the PEG-lipids in the lipid nanoparticles. The company also develops SER 214 a POZ conjugate of rotigotine for the treatment of early Parkinson's and Restless Leg Syndrome, which has completed phase 1a clinical trial. In addition, it develops POZ technology in lipid nanoparticle delivered ribonucleic acid vaccines for infectious diseases. Serina Therapeutics, Inc. was founded in 2006 and is based in Huntsville, Alabama.