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Simulations Plus Inc (SLP)

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Upturn Advisory Summary
12/12/2025: SLP (1-star) has a low Upturn Star Rating. Not recommended to BUY.
1 Year Target Price $22.33
1 Year Target Price $22.33
| 5 | Strong Buy |
| 0 | Buy |
| 1 | Hold |
| 0 | Sell |
| 0 | Strong Sell |
Analysis of Past Performance
Type Stock | Historic Profit -31.83% | Avg. Invested days 23 | Today’s Advisory Consider higher Upturn Star rating |
Upturn Star Rating ![]() | Upturn Advisory Performance | Stock Returns Performance |
Key Highlights
Company Size Small-Cap Stock | Market Capitalization 386.17M USD | Price to earnings Ratio - | 1Y Target Price 22.33 |
Price to earnings Ratio - | 1Y Target Price 22.33 | ||
Volume (30-day avg) 6 | Beta 1.17 | 52 Weeks Range 12.39 - 37.67 | Updated Date 12/15/2025 |
52 Weeks Range 12.39 - 37.67 | Updated Date 12/15/2025 | ||
Dividends yield (FY) - | Basic EPS (TTM) -3.22 |
Analyzing Revenue: Products, Geography and Growth
Revenue by Products
Product revenue - Year on Year
Revenue by Geography
Geography revenue - Year on Year
Earnings Date
Report Date - | When - | Estimate - | Actual - |
Profitability
Profit Margin -81.74% | Operating Margin (TTM) 3.2% |
Management Effectiveness
Return on Assets (TTM) 2.74% | Return on Equity (TTM) -42.13% |
Valuation
Trailing PE - | Forward PE 22.27 | Enterprise Value 354434291 | Price to Sales(TTM) 4.88 |
Enterprise Value 354434291 | Price to Sales(TTM) 4.88 | ||
Enterprise Value to Revenue 4.48 | Enterprise Value to EBITDA 24.11 | Shares Outstanding 20144564 | Shares Floating 16655123 |
Shares Outstanding 20144564 | Shares Floating 16655123 | ||
Percent Insiders 17.3 | Percent Institutions 79.18 |
About Simulations Plus Inc
Exchange NASDAQ | Headquaters Research Triangle Park, NC, United States | ||
IPO Launch date 1997-06-18 | CEO - | ||
Sector Healthcare | Industry Health Information Services | Full time employees 212 | Website https://www.simulations-plus.com |
Full time employees 212 | Website https://www.simulations-plus.com | ||
Simulations Plus, Inc. develops drug discovery and development software for modeling and simulation, and prediction of molecular properties utilizing artificial intelligence and machine learning based technology worldwide. It operates through Software and Services segments. The company offers GastroPlus, which predicts absorption, biopharmaceutics, pharmacokinetics, and pharmacodynamics in humans and animals; and DDDPlus and MembranePlus simulation products. It also provides products based on mechanistic and mathematical models, such as DILIsym, NAFLDsym, ILDsym, IPFsym, RENAsym, MITOsym, OBESITYsym, and Thales products. In addition, the company offers Absorption, Distribution, Metabolism, Excretion, and Toxicity (ADMET) predictor for chemistry-based computer program that takes molecular structures as inputs and predicts their properties; and MedChem Designer, as well as MonolixSuite products for modeling and simulation that allows for population analyses, rapid clinical trial data analyses, and regulatory submissions. Further, it provides clinical-pharmacology-based consulting services, which includes population pharmacokinetic and pharmacodynamic modeling, exposure-response analyses, clinical trial simulations, data programming, and technical writing services in support of regulatory submissions; and early drug discovery services. Additionally, the company offers creative and insightful consulting services to support its quantitative systems pharmacology and other modeling systems. The company serves pharmaceutical, biotechnology, agrochemical, cosmetics, and food industry companies, as well as academic and regulatory agencies. Simulations Plus, Inc. was incorporated in 1996 and is headquartered in Research Triangle Park, North Carolina.

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