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Semler Scientific Inc (SMLR)



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Upturn Advisory Summary
08/28/2025: SMLR (1-star) is currently NOT-A-BUY. Pass it for now.
Analysis of Past Performance
Type Stock | Historic Profit -7.4% | Avg. Invested days 30 | Today’s Advisory PASS |
Upturn Star Rating ![]() ![]() | Upturn Advisory Performance ![]() | Stock Returns Performance ![]() |
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Key Highlights
Company Size Small-Cap Stock | Market Capitalization 505.93M USD | Price to earnings Ratio - | 1Y Target Price 71 |
Price to earnings Ratio - | 1Y Target Price 71 | ||
Volume (30-day avg) - | Beta 1.43 | 52 Weeks Range 21.77 - 81.56 | Updated Date 06/29/2025 |
52 Weeks Range 21.77 - 81.56 | Updated Date 06/29/2025 | ||
Dividends yield (FY) - | Basic EPS (TTM) -2.39 |
Earnings Date
Report Date - | When - | Estimate - | Actual - |
Profitability
Profit Margin -60.69% | Operating Margin (TTM) -15.29% |
Management Effectiveness
Return on Assets (TTM) 4.18% | Return on Equity (TTM) -24.94% |
Valuation
Trailing PE - | Forward PE - | Enterprise Value 592336349 | Price to Sales(TTM) 10.28 |
Enterprise Value 592336349 | Price to Sales(TTM) 10.28 | ||
Enterprise Value to Revenue 12.03 | Enterprise Value to EBITDA 7 | Shares Outstanding 13141100 | Shares Floating 10076783 |
Shares Outstanding 13141100 | Shares Floating 10076783 | ||
Percent Insiders 12.03 | Percent Institutions 50.34 |
Upturn AI SWOT
Semler Scientific Inc
Company Overview
History and Background
Semler Scientific, Inc. was founded in 2007. It is a medical risk-assessment company focused on developing, manufacturing, and marketing products that help healthcare providers identify and treat chronic diseases.
Core Business Areas
- Peripheral Arterial Disease (PAD) Testing: Focuses on its flagship product, QuantaFlo, used to assess PAD risk. Also provides testing for other vascular diseases.
- Healthcare Solutions: This includes providing software and tools to assist healthcare providers with patient management and data analysis related to vascular diseases.
Leadership and Structure
The company is led by Doug Murphy-Chutorian, MD, as CEO. The structure is typical of a publicly traded company with a board of directors and executive management team overseeing operations, finance, and strategy.
Top Products and Market Share
Key Offerings
- QuantaFlo: QuantaFlo is a non-invasive, point-of-care testing device that measures blood flow to assess Peripheral Arterial Disease (PAD) risk. Market share data is challenging to find for this specific niche, but estimates place Semler as having a substantial portion of the PAD risk-assessment market. Competitors include companies providing ABI (Ankle-Brachial Index) testing equipment and other vascular assessment technologies. Specific revenue attributable to QuantaFlo is the majority of the company's total revenue.
Market Dynamics
Industry Overview
The medical risk-assessment industry is growing, driven by the increasing prevalence of chronic diseases, the aging population, and the emphasis on preventative care. There is growing focus on point of care diagnostic devices.
Positioning
Semler Scientific positions itself as a leader in non-invasive vascular assessment, particularly for PAD risk assessment. Its competitive advantage lies in the ease of use, speed, and accuracy of its QuantaFlo device.
Total Addressable Market (TAM)
The estimated TAM for PAD diagnostics and risk assessment is in the billions of dollars. Semler is capturing a portion of this TAM, and is working to expand its reach through increased adoption of its QuantaFlo device.
Upturn SWOT Analysis
Strengths
- Proprietary technology (QuantaFlo)
- Strong revenue growth
- High profit margins
- Strong cash position
- Established customer base
Weaknesses
- Concentration of revenue in one product (QuantaFlo)
- Dependence on reimbursement rates
- Limited product diversification
- Relatively small company size
Opportunities
- Expansion into new markets (international)
- Development of new products and applications
- Strategic partnerships and acquisitions
- Increased awareness of PAD risk
- Development of newer technology for more accurate readings.
Threats
- Changes in reimbursement policies
- Competition from larger medical device companies
- Technological obsolescence
- Economic downturn
- Regulatory changes
Competitors and Market Share
Key Competitors
- MLAB
- BIVV
- MXGL
Competitive Landscape
Semler Scientific has the advantage of a specialized product in the diagnostic market with a fast, easy to use, and noninvasive methodology for detecting PAD risk. Larger competitors may have broader product lines and established relationships.
Growth Trajectory and Initiatives
Historical Growth: Semler Scientific has demonstrated strong growth over the past few years, driven by increased adoption of QuantaFlo.
Future Projections: Analyst projections vary but generally anticipate continued growth for Semler Scientific, driven by increasing awareness of PAD and expanding market reach.
Recent Initiatives: Recent initiatives likely include expanding its sales force, investing in product development, and exploring strategic partnerships.
Summary
Semler Scientific is a medical risk-assessment company with a strong revenue stream from its QuantaFlo device. The company benefits from high profit margins and a healthy cash position, allowing it to expand into new markets and develop new products. Dependence on a single product and reimbursement rates are key risk factors. Semler Scientific needs to watch out for changes in these rates and innovate beyond the current product offerings.
Peer Comparison
Sources and Disclaimers
Data Sources:
- Company SEC filings (10-K, 10-Q)
- Company Investor Relations materials
- Analyst reports (where available)
- Industry reports
- Company Website
Disclaimers:
This analysis is based on publicly available information and is for informational purposes only. It should not be considered investment advice. Market share data is estimated and may not be precise.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About Semler Scientific Inc
Exchange NASDAQ | Headquaters Santa Clara, CA, United States | ||
IPO Launch date 2014-02-21 | CEO, President & Director Dr. Douglas Murphy-Chutorian M.D. | ||
Sector Healthcare | Industry Medical Devices | Full time employees 79 | Website https://www.semlerscientific.com |
Full time employees 79 | Website https://www.semlerscientific.com |
Semler Scientific, Inc. provides technology solutions to enhance the clinical effectiveness and efficiency of healthcare providers in the United States. The company's products include QuantaFlo, a four-minute in-office blood flow test that enables healthcare providers to use blood flow measurements as part of their examinations of a patient's vascular condition. The company's products serve cardiologists, internists, nephrologists, endocrinologists, podiatrists, family practitioners, healthcare insurance plans, integrated delivery networks, independent physician groups, and companies contracting with the healthcare industry, such as risk assessment groups and retailers. It offers its products through sales representatives and distributors. The company was incorporated in 2007 and is headquartered in Santa Clara, California.

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