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SenesTech Inc (SNES)

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Upturn Advisory Summary
01/09/2026: SNES (3-star) is currently NOT-A-BUY. Pass it for now.
1 Year Target Price $10
1 Year Target Price $10
| 0 | Strong Buy |
| 1 | Buy |
| 0 | Hold |
| 0 | Sell |
| 0 | Strong Sell |
Analysis of Past Performance
Type Stock | Historic Profit 51.59% | Avg. Invested days 58 | Today’s Advisory PASS |
Upturn Star Rating ![]() | Upturn Advisory Performance | Stock Returns Performance |
Key Highlights
Company Size Small-Cap Stock | Market Capitalization 11.80M USD | Price to earnings Ratio - | 1Y Target Price 10 |
Price to earnings Ratio - | 1Y Target Price 10 | ||
Volume (30-day avg) 1 | Beta 0.2 | 52 Weeks Range 1.30 - 6.24 | Updated Date 01/9/2026 |
52 Weeks Range 1.30 - 6.24 | Updated Date 01/9/2026 | ||
Dividends yield (FY) - | Basic EPS (TTM) -2.21 |
Analyzing Revenue: Products, Geography and Growth
Revenue by Products
Earnings Date
Report Date - | When - | Estimate - | Actual - |
Profitability
Profit Margin -253.54% | Operating Margin (TTM) -195.22% |
Management Effectiveness
Return on Assets (TTM) -38.54% | Return on Equity (TTM) -77.79% |
Valuation
Trailing PE - | Forward PE - | Enterprise Value 4239013 | Price to Sales(TTM) 5.13 |
Enterprise Value 4239013 | Price to Sales(TTM) 5.13 | ||
Enterprise Value to Revenue 1.84 | Enterprise Value to EBITDA 0.11 | Shares Outstanding 5223015 | Shares Floating 4510648 |
Shares Outstanding 5223015 | Shares Floating 4510648 | ||
Percent Insiders 4.21 | Percent Institutions 10.62 |
Upturn AI SWOT
SenesTech Inc

Company Overview
History and Background
SenesTech Inc. was founded in 2015 with the mission to develop and commercialize innovative solutions to address the challenges of aging, specifically focusing on cellular senescence. The company's core technology, a proprietary compound that targets senescent cells, has been a significant milestone. SenesTech has evolved from a research-focused entity to a company actively pursuing clinical development and commercialization of its lead product candidate.
Core Business Areas
- Senolytics Development: SenesTech is primarily focused on the development and commercialization of senolytic drugs. These drugs are designed to selectively eliminate senescent cells, which are thought to contribute to various age-related diseases and conditions.
Leadership and Structure
SenesTech Inc. is led by a management team with expertise in drug development, biotechnology, and business management. The company operates with a lean structure, typical of early-stage biotechnology firms, focusing on R&D, clinical trials, and intellectual property protection. Specific details on the entire leadership team and board of directors would require access to their latest filings.
Top Products and Market Share
Key Offerings
- Competitors: Unity Biotechnology (UBX),Oisu00edn Biotechnologies,Clearside Biomedical (CLSD)
- Description: SNF-001 is SenesTech's lead drug candidate, a senolytic compound designed to selectively eliminate senescent cells. It is currently being investigated for various age-related conditions, including osteoarthritis and potentially others. Market share data for SNF-001 is not yet available as it is in the clinical development phase. Key competitors in the broader senolytics space include Unity Biotechnology, Oisu00edn Biotechnologies, and Clearside Biomedical, among others.
- Market Share Data:
- Product Name 1: SNF-001
Market Dynamics
Industry Overview
The biotechnology and pharmaceutical industry, particularly the anti-aging and regenerative medicine sectors, is experiencing significant growth. The scientific understanding of cellular senescence and its role in aging has advanced considerably, leading to increased investment and research in senolytics. This field is characterized by innovation, high R&D costs, and a long drug development cycle with significant regulatory hurdles.
Positioning
SenesTech is positioned as an emerging player in the senolytics market. Its competitive advantage lies in its proprietary drug candidate and ongoing research into the therapeutic potential of targeting senescent cells. However, the company faces competition from established biotechnology firms and academic research institutions also exploring senolytic therapies.
Total Addressable Market (TAM)
The total addressable market for senolytics is potentially vast, encompassing numerous age-related diseases and conditions. While specific TAM figures for senolytics are still emerging, estimates for treating conditions like osteoarthritis alone run into billions of dollars globally. SenesTech aims to capture a segment of this market by successfully developing and commercializing SNF-001 and future senolytic compounds. Its current position is very early-stage, focusing on proving efficacy and safety in clinical trials.
Upturn SWOT Analysis
Strengths
- Proprietary senolytic compound (SNF-001)
- Focus on a rapidly growing and promising therapeutic area (senolytics)
- Potential for broad application across multiple age-related diseases
- Experienced scientific and management team
Weaknesses
- Early-stage clinical development with no approved products
- High R&D costs and long development timelines
- Reliance on successful clinical trial outcomes
- Limited financial resources compared to larger pharmaceutical companies
- Unproven long-term efficacy and safety of senolytics
Opportunities
- Growing scientific interest and investment in aging research and senolytics
- Potential to address significant unmet medical needs in age-related diseases
- Partnership and collaboration opportunities with larger pharmaceutical companies
- Expansion of senolytic applications to new disease indications
- Advancements in delivery mechanisms and therapeutic combinations
Threats
- Failure to demonstrate efficacy and safety in clinical trials
- Intense competition from other senolytic drug developers
- Regulatory hurdles and lengthy approval processes
- Potential for adverse side effects or unforeseen long-term consequences of senolytic treatment
- Changes in scientific understanding or market perception of senolytics
- Funding challenges for continued research and development
Competitors and Market Share
Key Competitors
- Unity Biotechnology (UBX)
- Oisu00edn Biotechnologies
- Clearside Biomedical (CLSD)
- Mayo Clinic (research institution)
- University of Michigan (research institution)
Competitive Landscape
SenesTech's competitive advantage lies in its proprietary senolytic compound and its focused approach to targeting cellular senescence. However, it faces significant competition from companies like Unity Biotechnology, which has a more advanced pipeline and has secured substantial funding. The competitive landscape is dynamic, with ongoing research and development efforts from various entities, including academic institutions.
Growth Trajectory and Initiatives
Historical Growth: SenesTech's historical growth has been driven by scientific advancements, securing funding for its research and development, and advancing its drug candidate through preclinical and early-stage clinical trials. This growth is measured more in terms of scientific milestones and pipeline progression than financial revenue.
Future Projections: Future projections for SenesTech are highly dependent on the success of its clinical trials for SNF-001. Analyst estimates, if available, would be based on the potential market penetration of senolytics and the success rate of drug development in this class. Significant revenue generation is contingent on regulatory approval and successful market launch.
Recent Initiatives: Recent initiatives would likely focus on advancing SNF-001 through its clinical trial phases, expanding its intellectual property portfolio, and potentially seeking strategic partnerships or additional funding to support its development pipeline.
Summary
SenesTech Inc. is an early-stage biotechnology company focused on developing senolytic drugs to combat age-related diseases. Its strength lies in its proprietary compound SNF-001 and its position in a high-growth therapeutic area. However, it faces significant weaknesses due to its pre-revenue status, reliance on clinical trial success, and substantial competition. The company must navigate regulatory hurdles and secure funding to advance its pipeline and capitalize on the vast market opportunities in aging research. Its success hinges on demonstrating the efficacy and safety of its senolytic therapy.
Similar Stocks
Sources and Disclaimers
Data Sources:
- Company filings (e.g., SEC filings)
- Financial news outlets (e.g., Bloomberg, Reuters)
- Biotechnology industry research reports
- Scientific publications
Disclaimers:
This JSON output is based on publicly available information and is for informational purposes only. It does not constitute financial advice. Investment decisions should be made after consulting with a qualified financial advisor and conducting thorough due diligence. Market share data and financial figures are estimates and subject to change.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About SenesTech Inc
Exchange NASDAQ | Headquaters Phoenix, AZ, United States | ||
IPO Launch date 2016-12-08 | CEO, President & Director Mr. Joel L. Fruendt | ||
Sector Basic Materials | Industry Specialty Chemicals | Full time employees 23 | Website https://www.senestech.com |
Full time employees 23 | Website https://www.senestech.com | ||
SenesTech, Inc. engages in the development and commercialization of a technology for managing animal pest populations through fertility control. It offers ContraPest, a liquid bait containing the active ingredients 4-vinylcyclohexene diepoxide and triptolide; and Evolve, a soft bait containing the active ingredient, cottonseed oil that limits the reproduction of male and female rats beginning with the first breeding cycles following consumption, as well as Evolve Mouse, a modified version of its bait technology containing the active ingredient cottonseed oil that limits reproduction of male and female mice after one to two breeding cycles following consumption. The company also provides teleconsulting and technical advisory services. The company was incorporated in 2004 and is headquartered in Phoenix, Arizona.

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