Surrozen Inc logo

Surrozen Inc(SRZN)

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ADVISORIES YOU CAN VERIFY
QUALITY SIGNAL
1-STAR RATING
PASS
LAST CLOSE
$29.54
09/25/2026
(24-hour delay)

Advisory History & Simulated Performance *

*as per simulation (see disclosures)
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Upturn Advisory & Investor View for SRZN

09/25/2026: SRZN (1-star) is currently NOT-A-BUY. Pass it for now.

Surrozen Inc is a clinical-stage biotechnology company that leverages proprietary platforms to modulate the Wnt pathway for tissue regeneration. The company’s primary strength lies in its highly specialized scientific expertise and a focused pipeline targeting conditions like inflammatory bowel disease. Its investment story centers on the potential for its clinical-stage assets to validate a previously 'undruggable' pathway, though the company remains in a high-risk, pre-commercial stage. Key risks include significant execution challenges, clinical failure, and the need for frequent capital raises. This stock is best suited for growth-oriented investors who can tolerate high volatility, with investors urged to monitor upcoming clinical data readouts as the primary catalysts.

How to Read the Upturn Advisory

The Upturn Star Rating and the current BUY, SELL, or PASS advisory are generated by Upturn’s AI advisory engine based on proprietary signal analysis, price behavior, advisory history, and historical signal performance.

Company fundamentals, valuation, risks, and news provide supporting context about the business.

Investor Fit

Investor styleFitWhy
Growth investorMixed fitThe company offers high-growth potential if clinical trials succeed, but the risk profile is extremely high.
Momentum investorWeak fitMomentum interest is typically inconsistent unless driven by major, positive clinical trial catalysts.
Value investorWeak fitAs a loss-making pre-commercial company, standard value metrics like P/E ratios are not applicable.
Dividend investorWeak fitThe company does not pay a dividend and focuses on cash preservation for R&D.
Low-risk investorWeak fitThe extreme volatility and binary nature of clinical outcomes are unsuitable for low-risk portfolios.

Risk Profile

Risk factorLevelWhy it matters
Price volatilityHighBiotech stocks are highly sensitive to clinical data, leading to sharp price swings.
Valuation riskHighValuations are highly speculative and depend entirely on the future success of clinical assets.
Competition risk (Biotech)HighThe company competes with massive pharmaceutical firms with superior financial resources.
Business qualityMediumThe science is robust, but the business is in the early stages with no revenue-generating products.
Dividend incomeLow / noneThe company is not an income-generating investment.
Execution riskHighSuccessful development and regulatory approval are inherently uncertain and difficult to execute.

Price Behavior

Downtrend
PRICE PATH

Downtrend

The stock has experienced a sustained decline in price over recent periods.

Extreme Price Shocks
PRICE STABILITY

Extreme Price Shocks

The stock has experienced exceptionally large and disruptive price movements during the period.

Analysis of Past Performance

Type Stock
Historic Profit -51.28%
Avg. Invested days 31
Today’s Advisory PASS
Upturn Advisory Rating upturn star rating icon
Upturn Advisory Performance Upturn Advisory Performance icon 2.0
Stock Returns Performance Upturn Returns Performance icon 1.0
Upturn Profits based on simulation icon Profits based on simulation
Upturn last close icon Last Close 09/25/2026

Upturn Scorecard

Upturn Star Rating

★★★★★
SRZN receives a 3-star rating, supported by solid analyst coverage. The rating is constrained by soft unit economics, soft company fundamentals, and weak price momentum.

Company Fundamentals

★★★★★
SRZN has soft overall fundamentals (2 stars), with soft financial health, weak growth momentum, and solid ownership. In FY2025 versus FY2024, growth and ownership metrics are mixed: negative earnings growth (-280.8%), soft cash generation (FCF margin -873.5%), negative revenue growth (-67.4%).

Financial Health Rating

★★★★★
SRZN's financial health is supported by moderate liquidity, including working-capital and asset support (WC/assets 82.7%). Cash strength is soft (2 stars), which helps explain the 2-star overall score.

Growth Momentum Score

★★★★★
SRZN's growth profile is soft, with the least-weak measure being revenue growth at -67.4% FY2025 versus FY2024. By comparison, while earnings growth (-280.8%, negative) and free-cash-flow growth (-72.0%, negative) hold the profile back, so recent growth is not broad-based across the business.

Ownership

★★★★★
Institutional ownership is 104.9% and approximately 39.3% of outstanding shares are publicly tradable, supporting liquidity and institutional participation. Insider ownership of 3.14% provides only moderate management-shareholder alignment.

Top 5 Institutional Investors

TCG Crossover Management, LLC 12.53%
Kalehua Capital Management LLC 6.55%
Boxer Capital Management, LLC 6.52%
StemPoint Capital LP 6.14%
Millennium Management LLC 5.81%

Unit Economics (Per $1K Revenue)

★★★★★
SRZN generates approximately $846 of gross profit, $-12,106 of operating income, and $-8,735 of free cash flow for every $1,000 of revenue. Based on FY2025 results. Strong margins, cash conversion, and capital efficiency support the rating.

Economic Dimensions

★★★★★
Effective Tax Rate: 0.00%

Quantitative Style Profile

★★★★★
SRZN has a relatively low-volatility profile. Weak momentum is the primary drawback, while valuation that is moderately attractive rather than deeply discounted.

Style Classification

Quality Focused

Low VolatilitySmall / Mid Cap RiskShort Squeeze Risk

Key Highlights

Company Size Small-Cap Stock
Market Capitalization 395.86M USD
Price to earnings Ratio -
1Y Target Price 46.4
Price to earnings Ratio -
1Y Target Price 46.4
Volume (30-day avg) 614.1K shares
Beta 0.56
52 Weeks Range 11.39 - 37.83
Updated Date 09/25/2026
52 Weeks Range 11.39 - 37.83
Updated Date 09/25/2026
Dividends yield (FY) -
Basic EPS (TTM) -83.49

How Company Makes Money

Business areaWhat it includesRetail investor read
Research & DevelopmentCollaborations, licensing agreements, and potential future product sales.The company currently makes very little money and is burning cash to build its future products.

Analyzing Revenue: Products, Geography and Growth

Revenue by Geography

Geography revenue - Year on Year

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Valuation

Trailing PE -
Forward PE -
Enterprise Value 94.21M
Price to Sales(TTM) 34.39
Enterprise Value 94.21M
Price to Sales(TTM) 34.39
Enterprise Value to Revenue 8.18
Enterprise Value to EBITDA 0.71
Shares Outstanding 11.75M
Shares Floating 4.62M
Shares Outstanding 11.75M
Shares Floating 4.62M
Percent Insiders 3.14
Percent Institutions 104.86

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Financial Metrics

🧭 Investment Snapshot

Total Revenue (Scale)

Information icon Total money earned from selling products or services before any costs. It is needed to understand the scale of the business and its ability to generate income.

Net Income (Profit)

Information icon Final profit after all expenses, interest, and taxes are deducted. It is needed to determine the overall profitability available to shareholders.

Free Cash Flow (Cash Strength)

Information icon Cash remaining after operating activities and capital expenditures, showing cash available for growth. It is needed to evaluate the company’s ability to invest, pay dividends, or reduce debt.

📈 Growth & Strength

Operating Income (Core Profit)

Information icon Profit from core operations after deducting all operating expenses. It is needed to measure how efficiently the company runs its primary business activities.

EBITDA (Cash Earnings)

Information icon Earnings before interest, taxes, depreciation, and amortization, indicating operating cash potential. It is needed to compare operating performance across companies without accounting or financing differences.

Gross Profit (Unit Profitability)

Information icon Revenue minus cost of revenue, showing profit after direct production costs. It is needed to evaluate core business profitability before overhead expenses.

🛡️ Financial Safety

Cash (Liquidity Buffer)

Information icon Total cash and cash equivalents on hand. It is needed to evaluate immediate liquidity and financial flexibility.

Total Debt (Leverage Risk)

Information icon Total debt including both short-term and long-term components. It is needed to assess the company’s leverage and financial risk.

Net Working Capital (Short-Term Health)

Information icon Current assets minus current liabilities, indicating short-term liquidity strength. It is needed to assess whether the company can meet its short-term obligations.

🧱 Balance Sheet Strength

Stockholder Equity (Net Worth)

Information icon Total equity value held by shareholders. It is needed to understand the net worth of the company from the owners’ perspective.

Total Assets (Asset Base)

Information icon The full value of everything the company owns, including cash, inventory, equipment, and investments. It is needed to understand the resource base used to generate revenue.

Income Before Tax (Pre-Tax Earnings)

Information icon Income before provision for income taxes. It is needed to analyze profitability independent of tax structures.

⚙️ Cost & Drag Factors

Cost of Revenue (Production Cost)

Information icon Direct costs required to produce and deliver the products or services sold. It is needed to assess efficiency in production and service delivery.

Total Operating Expenses (Operating Cost)

Information icon Indirect costs of running the business such as salaries, marketing, and administration. It is needed to understand how much it costs to sustain ongoing business operations.

Income Tax Expense (Tax Drag)

Information icon Amount of taxes paid or payable to the government. It is needed to evaluate the impact of taxation on overall profitability.

About Surrozen Inc

Exchange NASDAQ
Headquarters South San Francisco, CA, United States
IPO Launch date 2021-01-11
CEO, President & Director Mr. Craig C. Parker M.B.A.
Sector Healthcare
Industry Biotechnology
Full time employees 44
Full time employees 44

Surrozen, Inc., a biotechnology company, discovers and develops product candidates to selectively modulate the Wnt pathway for tissue repair. Its lead product candidates are antibody-based therapeutics that target various disease areas, including diseases of the eye, intestine, liver, lung, retina, kidney, cochlea, cornea, skin, pancreas, and central nervous system. The company develops SZN-814, which combines Frizzled 4 (Fzd4 agonism) and vascular endothelial growth factor (VEGF antagonism) to treat diabetic macular edema (DME), neovascular age-related macular degeneration (wet AMD), and retinopathy indications; SZN-8143, which combines Fzd4 agonism, VEGF antagonism, and interleukin-6, or IL-6 for the treatment of DME/wet AMD/uveitic macular edema; and SZN-413, a Fzd4 targeted bi-specific antibody for the treatment of retinal vascular associated diseases. Surrozen, Inc. has a collaboration and license agreement with Boehringer Ingelheim International GmbH to research, develop, and commercialize Fzd4 bi-specific antibodies; and a research collaboration agreement with TCGFB, Inc. to discover antibody therapeutics targeting transforming growth factor beta, or TGF-ß, for the treatment of patients with idiopathic pulmonary fibrosis. Surrozen, Inc. was founded in 2015 and is headquartered in South San Francisco, California.