Tenax Therapeutics Inc logo

Tenax Therapeutics Inc(TENX)

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ADVISORIES YOU CAN VERIFY
QUALITY SIGNAL
3-STAR RATING
PASS
LAST CLOSE
$1.81
09/25/2026
(24-hour delay)

Advisory History & Simulated Performance *

*as per simulation (see disclosures)
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Upturn Advisory & Investor View for TENX

09/25/2026: TENX (3-star) is currently NOT-A-BUY. Pass it for now.

Tenax Therapeutics is a clinical-stage biotechnology company focused on developing cardiovascular therapies, most notably its lead candidate Levosimendan. The company's primary investment story centers on the potential for its novel inodilator to address significant unmet medical needs in heart failure and pulmonary hypertension. While this focus offers high growth potential, the firm lacks current commercial revenue and faces substantial execution risks related to clinical trial outcomes and regulatory hurdles. Investors should note that the company is capital-intensive and requires ongoing financing. Consequently, Tenax may best suit risk-tolerant investors who monitor clinical trial progress and binary regulatory milestones as key developments.

How to Read the Upturn Advisory

The Upturn Star Rating and the current BUY, SELL, or PASS advisory are generated by Upturn’s AI advisory engine based on proprietary signal analysis, price behavior, advisory history, and historical signal performance.

Company fundamentals, valuation, risks, and news provide supporting context about the business.

Investor Fit

Investor styleFitWhy
Growth investorMixed fitThe company offers potential high growth if clinical trials succeed, but lacks a current revenue-generating commercial product.
Momentum investorStrong fit while signal remains positiveMomentum investors may find value during clinical trial milestone announcements or positive regulatory news cycles.
Value investorWeak fitThe company is not currently profitable, making traditional valuation metrics like P/E ratios inapplicable.
Dividend investorWeak fitTenax does not pay dividends and requires significant capital for development.
Low-risk investorWeak fitThe high volatility and clinical binary risk profile are generally unsuitable for risk-averse investors.

Risk Profile

Risk factorLevelWhy it matters
Price volatilityHighThe stock is subject to sharp price swings based on clinical trial results and financing news.
Valuation riskHighValuation is speculative and heavily dependent on the projected future success of its clinical pipeline.
Competition risk (Cardiovascular)Medium / highThe company competes with much larger, well-capitalized firms in the cardiovascular drug market.
Business qualityMediumThe company is in the process of validating its business model through clinical trial success.
Dividend incomeLow / noneThere is no income component to the investment.
Execution riskHighFailure to meet clinical endpoints would severely impact the viability of the company.

Price Behavior

Steep Decline
PRICE PATH

Steep Decline

The stock price has dropped sharply with strong downward pressure.

Extreme Price Shocks
PRICE STABILITY

Extreme Price Shocks

The stock has experienced exceptionally large and disruptive price movements during the period.

Analysis of Past Performance

Type Stock
Historic Profit 161.96%
Avg. Invested days 53
Today’s Advisory PASS
Upturn Advisory Rating upturn star rating icon
Upturn Advisory Performance Upturn Advisory Performance icon 4.0
Stock Returns Performance Upturn Returns Performance icon 5.0
Upturn Profits based on simulation icon Profits based on simulation
Upturn last close icon Last Close 09/25/2026

Upturn Scorecard

Upturn Star Rating

★★★★★
TENX receives a 3-star rating, supported by solid analyst coverage. The rating is constrained by weak unit economics, soft quantitative characteristics, and weak price momentum.

Company Fundamentals

★★★★★
TENX has moderate overall fundamentals (3 stars), with moderate financial health, soft growth momentum, and solid ownership. In FY2025 versus FY2024, growth and ownership metrics are mixed: negative earnings growth (-198.8%), soft cash generation (FCF margin 0.0%), slightly negative revenue growth (+0.0%).

Financial Health Rating

★★★★★
TENX's financial health is supported by strong efficiency, including operating-expense and cost-of-revenue discipline (opex 0.0% of revenue). Profitability is weak (1 stars), which helps explain the 3-star overall score.

Growth Momentum Score

★★★★★
TENX's growth profile is soft, with the least-weak measure being revenue growth at +0.0% FY2025 versus FY2024. By comparison, while earnings growth (-198.8%, negative) and free-cash-flow growth (-141.7%, negative) hold the profile back, so recent growth is not broad-based across the business.

Ownership

★★★★★
Institutional ownership is 110.8% and approximately 82.2% of outstanding shares are publicly tradable, supporting liquidity and institutional participation. Insider ownership is only 0.15%, which materially reduces the ownership score.

Top 5 Institutional Investors

T. Rowe Price Associates, Inc. 7.89%
Vivo Capital, LLC 6.68%
HHG PLC 4.85%
Perceptive Advisors LLC 4.54%
VR Adviser, LLC 4.48%

Unit Economics (Per $1K Revenue)

★★★★★
TENX generates approximately $0 of gross profit, $-0 of operating income, and $-0 of free cash flow for every $1,000 of revenue. Based on FY2025 results. Strong margins, cash conversion, and capital efficiency support the rating.

Economic Dimensions

★★★★★
Effective Tax Rate: 0.00%

Quantitative Style Profile

★★★★★
TENX has a liquid profile. Weak momentum is the primary drawback, while valuation that is moderately attractive rather than deeply discounted.

Style Classification

Quality Focused

Small / Mid Cap RiskShort Squeeze RiskHighly Liquid / Institution-Friendly

Key Highlights

Company Size Small-Cap Stock
Market Capitalization 67.74M USD
Price to earnings Ratio -
1Y Target Price 12.56
Price to earnings Ratio -
1Y Target Price 12.56
Volume (30-day avg) 5.9M shares
Beta 0.82
52 Weeks Range 1.31 - 19.40
Updated Date 09/27/2026
52 Weeks Range 1.31 - 19.40
Updated Date 09/27/2026
Dividends yield (FY) -
Basic EPS (TTM) -1.48

How Company Makes Money

Business areaWhat it includesRetail investor read
Cardiovascular TherapeuticsClinical development of Levosimendan for PH-HFpEF.The company is currently not generating commercial sales and is funding development through investor capital.

Analyzing Revenue: Products, Geography and Growth

Revenue by Products

Product revenue - Year on Year

Revenue by Geography

Geography revenue - Year on Year

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Valuation

Trailing PE -
Forward PE 0.3
Enterprise Value -46.31M
Price to Sales(TTM) 414.72
Enterprise Value -46.31M
Price to Sales(TTM) 414.72
Enterprise Value to Revenue 263.34
Enterprise Value to EBITDA -0.14
Shares Outstanding 37.42M
Shares Floating 30.78M
Shares Outstanding 37.42M
Shares Floating 30.78M
Percent Insiders 0.15
Percent Institutions 110.81

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Financial Metrics

🧭 Investment Snapshot

Total Revenue (Scale)

Information icon Total money earned from selling products or services before any costs. It is needed to understand the scale of the business and its ability to generate income.

Net Income (Profit)

Information icon Final profit after all expenses, interest, and taxes are deducted. It is needed to determine the overall profitability available to shareholders.

Free Cash Flow (Cash Strength)

Information icon Cash remaining after operating activities and capital expenditures, showing cash available for growth. It is needed to evaluate the company’s ability to invest, pay dividends, or reduce debt.

📈 Growth & Strength

Operating Income (Core Profit)

Information icon Profit from core operations after deducting all operating expenses. It is needed to measure how efficiently the company runs its primary business activities.

EBITDA (Cash Earnings)

Information icon Earnings before interest, taxes, depreciation, and amortization, indicating operating cash potential. It is needed to compare operating performance across companies without accounting or financing differences.

Gross Profit (Unit Profitability)

Information icon Revenue minus cost of revenue, showing profit after direct production costs. It is needed to evaluate core business profitability before overhead expenses.

🛡️ Financial Safety

Cash (Liquidity Buffer)

Information icon Total cash and cash equivalents on hand. It is needed to evaluate immediate liquidity and financial flexibility.

Total Debt (Leverage Risk)

Information icon Total debt including both short-term and long-term components. It is needed to assess the company’s leverage and financial risk.

Net Working Capital (Short-Term Health)

Information icon Current assets minus current liabilities, indicating short-term liquidity strength. It is needed to assess whether the company can meet its short-term obligations.

🧱 Balance Sheet Strength

Stockholder Equity (Net Worth)

Information icon Total equity value held by shareholders. It is needed to understand the net worth of the company from the owners’ perspective.

Total Assets (Asset Base)

Information icon The full value of everything the company owns, including cash, inventory, equipment, and investments. It is needed to understand the resource base used to generate revenue.

Income Before Tax (Pre-Tax Earnings)

Information icon Income before provision for income taxes. It is needed to analyze profitability independent of tax structures.

⚙️ Cost & Drag Factors

Cost of Revenue (Production Cost)

Information icon Direct costs required to produce and deliver the products or services sold. It is needed to assess efficiency in production and service delivery.

Total Operating Expenses (Operating Cost)

Information icon Indirect costs of running the business such as salaries, marketing, and administration. It is needed to understand how much it costs to sustain ongoing business operations.

Income Tax Expense (Tax Drag)

Information icon Amount of taxes paid or payable to the government. It is needed to evaluate the impact of taxation on overall profitability.

About Tenax Therapeutics Inc

Exchange NASDAQ
Headquarters Chapel Hill, NC, United States
IPO Launch date 1997-01-02
CEO, President & Director Mr. Christopher T. Giordano
Sector Healthcare
Industry Biotechnology
Full time employees 14
Full time employees 14

Tenax Therapeutics, Inc., a development-stage pharmaceutical company, develops novel cardiopulmonary therapies in the United States. It develops TNX-101, TNX-102, and TNX-103 (levosimendan) that have completed phase II clinical trials for the treatment of patients with pulmonary hypertension in heart failure with preserved ejection fraction and associated pulmonary hypertension; and TNX-201 (imatinib), a tyrosine kinase inhibitor for the treatment of chronic myeloid leukemia. The company was formerly known as Oxygen Biotherapeutics, Inc. and changed its name to Tenax Therapeutics, Inc. in September 2014. Tenax Therapeutics, Inc. was founded in 1967 and is headquartered in Chapel Hill, North Carolina.