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TriSalus Life Sciences Inc. (TLSI)

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Upturn Advisory Summary
12/05/2025: TLSI (1-star) has a low Upturn Star Rating. Not recommended to BUY.
1 Year Target Price $11.36
1 Year Target Price $11.36
| 6 | Strong Buy |
| 2 | Buy |
| 0 | Hold |
| 0 | Sell |
| 0 | Strong Sell |
Analysis of Past Performance
Type Stock | Historic Profit -23.06% | Avg. Invested days 45 | Today’s Advisory Consider higher Upturn Star rating |
Upturn Star Rating ![]() | Upturn Advisory Performance | Stock Returns Performance |
Key Highlights
Company Size Small-Cap Stock | Market Capitalization 352.75M USD | Price to earnings Ratio - | 1Y Target Price 11.36 |
Price to earnings Ratio - | 1Y Target Price 11.36 | ||
Volume (30-day avg) 8 | Beta 0.43 | 52 Weeks Range 3.42 - 7.32 | Updated Date 12/6/2025 |
52 Weeks Range 3.42 - 7.32 | Updated Date 12/6/2025 | ||
Dividends yield (FY) - | Basic EPS (TTM) -2.12 |
Earnings Date
Report Date 2025-11-13 | When - | Estimate -0.165 | Actual -0.96 |
Profitability
Profit Margin -98.45% | Operating Margin (TTM) -77.94% |
Management Effectiveness
Return on Assets (TTM) -61.1% | Return on Equity (TTM) -496.21% |
Valuation
Trailing PE - | Forward PE - | Enterprise Value 364185035 | Price to Sales(TTM) 8.77 |
Enterprise Value 364185035 | Price to Sales(TTM) 8.77 | ||
Enterprise Value to Revenue 9.06 | Enterprise Value to EBITDA -5.96 | Shares Outstanding 49964311 | Shares Floating 39539258 |
Shares Outstanding 49964311 | Shares Floating 39539258 | ||
Percent Insiders 42.41 | Percent Institutions 19.46 |
Upturn AI SWOT
TriSalus Life Sciences Inc.

Company Overview
History and Background
TriSalus Life Sciences Inc. is a privately held company focused on developing novel therapeutics and drug delivery systems for various medical conditions. Information on its founding year and specific historical milestones is not readily available in public domain as it is a private entity. Its evolution is centered around advancing its proprietary technology platforms.
Core Business Areas
- Therapeutic Development: Focuses on developing innovative drug candidates for unmet medical needs. This includes utilizing their proprietary drug delivery systems to enhance efficacy and reduce side effects.
- Drug Delivery Systems: Development and application of advanced drug delivery technologies, such as their proprietary platform for targeted delivery and sustained release of therapeutic agents.
Leadership and Structure
As a privately held company, detailed information about its leadership team and organizational structure is not publicly disclosed. Leadership is typically comprised of experienced professionals in the pharmaceutical and biotechnology sectors.
Top Products and Market Share
Key Offerings
- Description: A novel drug delivery technology designed for targeted and controlled release of therapeutic agents. This platform aims to improve drug efficacy, reduce systemic toxicity, and enhance patient compliance. Specific details on market share, user numbers, or revenue are not publicly available due to its private status. Competitors in the drug delivery space include established pharmaceutical companies and specialized biotechnology firms offering various advanced delivery methods (e.g., liposomes, nanoparticles, long-acting injectables).
- Product Name: TriSalus Proprietary Drug Delivery Platform
Market Dynamics
Industry Overview
TriSalus Life Sciences operates within the pharmaceutical and biotechnology sectors, specifically focusing on drug discovery, development, and advanced drug delivery systems. This industry is characterized by high R&D investment, long product development cycles, stringent regulatory requirements, and intense competition. Key trends include personalized medicine, biologics, and innovative delivery mechanisms.
Positioning
TriSalus Life Sciences positions itself as an innovator in drug delivery, aiming to differentiate its therapeutic candidates by leveraging its proprietary technology to improve existing treatments and address novel therapeutic targets. Its competitive advantage lies in its unique technological approach to drug delivery.
Total Addressable Market (TAM)
The TAM for TriSalus's potential products is vast, encompassing the global markets for various therapeutic areas it targets (e.g., oncology, infectious diseases, chronic conditions) and the market for advanced drug delivery technologies. The global drug delivery market alone is projected to reach hundreds of billions of dollars. TriSalus aims to capture a share of this market by offering differentiated solutions.
Upturn SWOT Analysis
Strengths
- Proprietary and innovative drug delivery technology platform.
- Potential for enhanced therapeutic efficacy and reduced side effects.
- Experienced leadership in pharmaceutical R&D (assumed).
- Focus on addressing unmet medical needs.
Weaknesses
- As a private company, limited public financial transparency.
- Long development timelines and high R&D costs inherent in drug development.
- Dependence on successful clinical trial outcomes.
- Need for significant capital investment for development and commercialization.
Opportunities
- Growing demand for advanced drug delivery systems.
- Partnership opportunities with larger pharmaceutical companies for co-development or licensing.
- Expansion into new therapeutic areas.
- Potential for out-licensing of its delivery technology.
Threats
- Intense competition from established and emerging biotechnology companies.
- Regulatory hurdles and the risk of trial failures.
- Patent expirations and generic competition for related drugs.
- Changes in healthcare policies and reimbursement landscapes.
Competitors and Market Share
Key Competitors
- Johnson & Johnson (JNJ)
- Pfizer Inc. (PFE)
- Merck & Co., Inc. (MRK)
- Novartis AG (NVS)
- Roche Holding AG (RHHBY)
Competitive Landscape
TriSalus Life Sciences Inc. operates in a highly competitive landscape dominated by large pharmaceutical and biotechnology companies with extensive R&D resources and established market presence. Its competitive advantages are its specialized focus on innovative drug delivery technology and its potential to develop differentiated therapies. However, it faces significant challenges in competing with the scale and established pipelines of larger players.
Growth Trajectory and Initiatives
Historical Growth: Growth trajectory for a private company is primarily driven by its success in R&D, securing funding, and achieving development milestones. Specific historical growth data is not public.
Future Projections: Future growth projections are speculative and would depend on the successful development and commercialization of its pipeline products and technologies. Analyst estimates are not publicly available.
Recent Initiatives: Specific recent strategic initiatives are not publicly disclosed but are likely focused on advancing its drug candidates through preclinical and clinical development, and potentially seeking strategic partnerships or funding rounds.
Summary
TriSalus Life Sciences Inc. is a promising private biotechnology company with a focus on advanced drug delivery systems. Its proprietary technology offers potential for improved therapeutic outcomes, a significant strength in a competitive market. However, as a private entity, its lack of financial transparency and the inherent risks of drug development are notable weaknesses. Capitalizing on the growing demand for innovative drug delivery and forging strategic partnerships are key opportunities, while regulatory hurdles and strong competition pose significant threats.
Similar Stocks
Sources and Disclaimers
Data Sources:
- General industry knowledge of pharmaceutical and biotechnology sectors.
- Publicly available information on drug delivery technologies.
- Hypothetical competitor data for illustrative purposes, as TriSalus is private.
Disclaimers:
This analysis is based on publicly available information and general industry knowledge. TriSalus Life Sciences Inc. is a privately held company, and therefore, detailed financial data and operational specifics are not publicly disclosed. Market share data for competitors is illustrative and based on broad industry segments. This information is for informational purposes only and should not be considered investment advice. Investors should conduct their own due diligence.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About TriSalus Life Sciences Inc.
Exchange NASDAQ | Headquaters Westminster, CO, United States | ||
IPO Launch date 2023-08-10 | CEO, President & Director Ms. Mary T. Szela B.S.N., M.B.A. | ||
Sector Healthcare | Industry Medical Devices | Full time employees 110 | Website https://trisaluslifesci.com |
Full time employees 110 | Website https://trisaluslifesci.com | ||
TriSalus Life Sciences, Inc. engages in the research, development, and commercialization of drug delivery technology platform and immuno-oncology therapeutics to improve outcomes for patients with difficult-to-treat liver and pancreatic cancers. It offers Pressure Enabled Drug Delivery infusion systems, such as the TriNav infusion system, which is used in transarterial radioembolization and chemoembolization procedures for patients with liver cancer and metastases; and the Pancreatic Retrograde Venous Infusion device, which is in Phase 1 clinical trial for treating locally advanced pancreatic cancer. The company is also developing nelitolimod, an investigational immunotherapeutic in Phase 1 clinical trial for the treatment of uveal melanoma, intrahepatic cholangiocarcinoma, hepatocellular carcinoma, and pancreatic cancer. It serves interventional radiologists, IR technicians, medical oncologists, nursing support, value analysis committee staff, and patients through its sales representatives and sales managers. The company was founded in 2009 and is headquartered in Westminster, Colorado.

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