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TLSI
Upturn stock ratingUpturn stock rating

TriSalus Life Sciences Inc. (TLSI)

Upturn stock ratingUpturn stock rating
$5.45
Last Close (24-hour delay)
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PASS
  • BUY Advisory
  • SELL Advisory (Profit)​
  • SELL Advisory (Loss)​
  • Profit
  • Loss
  • Pass (Skip investing)
Upturn Stock infoUpturn Stock info Stock price based on last close
*as per simulation
(see disclosures)
Time period over
  • ALL
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Upturn Advisory Summary

06/30/2025: TLSI (1-star) is currently NOT-A-BUY. Pass it for now.

Upturn Star Rating

rating

Not Recommended Performance

These Stocks/ETFs, based on Upturn Advisory, consistently fall short of market performance, signaling caution before investing.

Number of Analysts

rating

8 Analysts rated it

Moderately tracked stock, growing coverage, gaining market and investor attention.

1 Year Target Price $11.31

1 Year Target Price $11.31

Analysts Price Target For last 52 week
$11.31Target price
Low$3.5
Current$5.45
high$6.04

Analysis of Past Performance

Type Stock
Historic Profit -17.6%
Avg. Invested days 64
Today’s Advisory PASS
Upturn Star Rating Upturn stock ratingUpturn stock rating
Upturn Advisory Performance Upturn Advisory Performance 3.0
Stock Returns Performance Upturn Returns Performance 1.0
Upturn Profits based on simulationUpturn Profits based on simulation Profits based on simulation
Upturn Profits based on simulationUpturn Profits based on simulation Last Close 06/30/2025

Key Highlights

Company Size Small-Cap Stock
Market Capitalization 206.97M USD
Price to earnings Ratio -
1Y Target Price 11.31
Price to earnings Ratio -
1Y Target Price 11.31
Volume (30-day avg) 8
Beta 0.47
52 Weeks Range 3.50 - 6.04
Updated Date 07/1/2025
52 Weeks Range 3.50 - 6.04
Updated Date 07/1/2025
Dividends yield (FY) -
Basic EPS (TTM) -1.1

Earnings Date

Report Date -
When -
Estimate -
Actual -

Profitability

Profit Margin -84.67%
Operating Margin (TTM) -79.95%

Management Effectiveness

Return on Assets (TTM) -85.52%
Return on Equity (TTM) -496.21%

Valuation

Trailing PE -
Forward PE -
Enterprise Value 226324675
Price to Sales(TTM) 6.44
Enterprise Value 226324675
Price to Sales(TTM) 6.44
Enterprise Value to Revenue 7.04
Enterprise Value to EBITDA -5.96
Shares Outstanding 37975800
Shares Floating 29370602
Shares Outstanding 37975800
Shares Floating 29370602
Percent Insiders 50.44
Percent Institutions 8.11

Analyst Ratings

Rating 3
Target Price 11.31
Buy 2
Strong Buy 6
Buy 2
Strong Buy 6
Hold -
Sell -
Strong Sell -
Strong Sell -

ai summary icon Upturn AI SWOT

TriSalus Life Sciences Inc.

stock logo

Company Overview

overview logo History and Background

TriSalus Life Sciences Inc. focuses on developing and commercializing technologies to treat liver and pancreatic tumors. The company was formerly known as Surefire Medical, Inc. and changed its name in July 2020. It went public through a SPAC merger in 2023.

business area logo Core Business Areas

  • Drug-eluting System: TriSalus is dedicated to improving patient outcomes through the development of innovative delivery systems, particularly focused on regional cancer therapies.
  • Pressure-Enabled Drug Delivery: Their core technology centers around pressure-enabled drug delivery to improve the penetration and efficacy of therapeutics in solid tumors of the liver and pancreas.

leadership logo Leadership and Structure

The leadership team includes individuals with experience in medical device development and commercialization. The organizational structure reflects a focus on research and development, clinical trials, and commercial operations.

Top Products and Market Share

overview logo Key Offerings

  • TriNav Infusion System: TriNav is their primary product, designed to deliver cancer therapeutics directly to liver tumors under pressure. Market share data is not widely published but the product competes with conventional TACE. Competitors: Boston Scientific, Cook Medical, Terumo.
  • MATCH-ITSM Clinical Study: This study explores the use of TriNav in combination with immunotherapy for liver tumors. Early results suggest improved response rates. Competitors include researchers employing other drug delivery systems in combination with immunotherapies.

Market Dynamics

industry overview logo Industry Overview

The interventional oncology market is growing due to increasing cancer incidence and advancements in minimally invasive techniques. There is a strong need for more effective therapies for liver and pancreatic cancer.

Positioning

TriSalus positions itself as a leader in pressure-enabled drug delivery for liver and pancreatic tumors. Their competitive advantage lies in their proprietary technology and focus on regional therapy.

Total Addressable Market (TAM)

The TAM for liver and pancreatic cancer therapeutics is estimated to be several billion dollars annually. TriSalus is positioning themselves to capture a share of this market by addressing unmet needs in drug delivery.

Upturn SWOT Analysis

Strengths

  • Proprietary pressure-enabled drug delivery technology
  • Focus on difficult-to-treat liver and pancreatic tumors
  • Potential for synergistic combination with immunotherapies
  • Experienced leadership team

Weaknesses

  • Limited commercial history as a public company
  • Dependence on regulatory approvals for product expansion
  • Potential for competition from established players
  • Reliance on clinical trial outcomes

Opportunities

  • Expansion into new indications and markets
  • Partnerships with pharmaceutical companies
  • Development of next-generation drug delivery systems
  • Positive clinical trial results driving adoption

Threats

  • Regulatory setbacks
  • Competition from established medical device companies
  • Negative clinical trial results
  • Changes in reimbursement policies

Competitors and Market Share

competitor logo Key Competitors

  • BSX
  • COOK
  • TRMO

Competitive Landscape

TriSalus is a smaller player in a market dominated by larger medical device companies. Its advantage is its novel technology, but it faces challenges in competing with the established sales and marketing infrastructure of its competitors.

Growth Trajectory and Initiatives

Historical Growth: Historical growth data is limited due to the recent public offering.

Future Projections: Future growth is expected to be driven by the adoption of TriNav and potential approvals of new products and indications. Analyst estimates vary.

Recent Initiatives: Recent initiatives include the ongoing MATCH-ITSM clinical study and efforts to expand the commercial reach of TriNav.

Summary

TriSalus Life Sciences Inc. is a promising company with a novel drug delivery technology focused on difficult-to-treat cancers. Its success depends on positive clinical trial results and successful commercialization efforts. The company faces competition from larger players and relies on regulatory approvals. Monitoring their financial performance and clinical development will be crucial in assessing their long-term viability.

Peer Comparison

Sources and Disclaimers

Data Sources:

  • TriSalus Life Sciences Inc. SEC Filings
  • Company Website
  • Analyst Reports
  • Industry Reports

Disclaimers:

This analysis is for informational purposes only and should not be considered financial advice. Market share data is based on available information and may not be precise. Investment decisions should be based on thorough research and consultation with a financial professional.

Upturn AI SummarizationUpturn AI Summarization AI Summarization is directionally correct and might not be accurate.

Upturn AI SummarizationUpturn AI Summarization Summarized information shown could be a few years old and not current.

Upturn AI SummarizationUpturn AI Summarization Fundamental Rating based on AI could be based on old data.

Upturn AI SummarizationUpturn AI Summarization AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.

About TriSalus Life Sciences Inc.

Exchange NASDAQ
Headquaters Westminster, CO, United States
IPO Launch date 2023-08-10
CEO, President & Director Ms. Mary T. Szela B.S.N., M.B.A.
Sector Healthcare
Industry Medical Devices
Full time employees 110
Full time employees 110

TriSalus Life Sciences, Inc. engages in the research, development, and commercialization of drug delivery technology platform and immuno-oncology therapeutics to improve outcomes for patients with difficult-to-treat liver and pancreatic cancers. It offers Pressure Enabled Drug Delivery infusion systems, such as the TriNav infusion system, which is used in transarterial radioembolization and chemoembolization procedures for patients with liver cancer and metastases; and the Pancreatic Retrograde Venous Infusion device, which is in Phase 1 clinical trial for treating locally advanced pancreatic cancer. The company is also developing nelitolimod, an investigational immunotherapeutic in Phase 1 clinical trial for the treatment of uveal melanoma, intrahepatic cholangiocarcinoma, hepatocellular carcinoma, and pancreatic cancer. It serves interventional radiologists, IR technicians, medical oncologists, nursing support, value analysis committee staff, and patients through its sales representatives and sales managers. The company was founded in 2009 and is headquartered in Westminster, Colorado.