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TYRA
Upturn stock ratingUpturn stock rating

Tyra Biosciences Inc (TYRA)

Upturn stock ratingUpturn stock rating
$9.57
Last Close (24-hour delay)
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PASS
  • BUY Advisory
  • SELL Advisory (Profit)​
  • SELL Advisory (Loss)​
  • Profit
  • Loss
  • Pass (Skip investing)
Upturn Stock infoUpturn Stock info Stock price based on last close
*as per simulation
(see disclosures)
Time period over
  • ALL
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Upturn Advisory Summary

06/30/2025: TYRA (1-star) is currently NOT-A-BUY. Pass it for now.

Upturn Star Rating

rating

Not Recommended Performance

These Stocks/ETFs, based on Upturn Advisory, consistently fall short of market performance, signaling caution before investing.

Number of Analysts

rating

8 Analysts rated it

Moderately tracked stock, growing coverage, gaining market and investor attention.

1 Year Target Price $30.14

1 Year Target Price $30.14

Analysts Price Target For last 52 week
$30.14Target price
Low$6.42
Current$9.57
high$29.6

Analysis of Past Performance

Type Stock
Historic Profit -69.98%
Avg. Invested days 18
Today’s Advisory PASS
Upturn Star Rating Upturn stock ratingUpturn stock rating
Upturn Advisory Performance Upturn Advisory Performance 1.0
Stock Returns Performance Upturn Returns Performance 1.0
Upturn Profits based on simulationUpturn Profits based on simulation Profits based on simulation
Upturn Profits based on simulationUpturn Profits based on simulation Last Close 06/30/2025

Key Highlights

Company Size Small-Cap Stock
Market Capitalization 483.92M USD
Price to earnings Ratio -
1Y Target Price 30.14
Price to earnings Ratio -
1Y Target Price 30.14
Volume (30-day avg) 8
Beta 1.07
52 Weeks Range 6.42 - 29.60
Updated Date 06/29/2025
52 Weeks Range 6.42 - 29.60
Updated Date 06/29/2025
Dividends yield (FY) -
Basic EPS (TTM) -1.63

Earnings Date

Report Date -
When -
Estimate -
Actual -

Profitability

Profit Margin -
Operating Margin (TTM) -

Management Effectiveness

Return on Assets (TTM) -19%
Return on Equity (TTM) -27.04%

Valuation

Trailing PE -
Forward PE -
Enterprise Value 172694048
Price to Sales(TTM) -
Enterprise Value 172694048
Price to Sales(TTM) -
Enterprise Value to Revenue -
Enterprise Value to EBITDA -6.95
Shares Outstanding 53178000
Shares Floating 14033672
Shares Outstanding 53178000
Shares Floating 14033672
Percent Insiders 3.69
Percent Institutions 109.09

Analyst Ratings

Rating 3
Target Price 30.14
Buy 2
Strong Buy 6
Buy 2
Strong Buy 6
Hold -
Sell -
Strong Sell -
Strong Sell -

ai summary icon Upturn AI SWOT

Tyra Biosciences Inc

stock logo

Company Overview

overview logo History and Background

Tyra Biosciences Inc. was founded in 2018. It focuses on developing precision medicines to overcome tumor resistance and improve outcomes for cancer patients. The company has advanced multiple programs into clinical development since its inception.

business area logo Core Business Areas

  • Oncology Drug Development: Focuses on developing small molecule inhibitors for genetically defined cancers.

leadership logo Leadership and Structure

The company is led by a management team with experience in oncology drug development and business strategy. The organizational structure is typical of a biotech company, with distinct departments for research, development, clinical operations, and business development.

Top Products and Market Share

overview logo Key Offerings

  • TYRA-300: TYRA-300 is an investigational selective inhibitor of fibroblast growth factor receptor (FGFR) being developed for metastatic urothelial cancer and other FGFR-altered solid tumors. Clinical trials are ongoing. Competitors include existing FGFR inhibitors and other emerging therapies. Market share data is currently unavailable.
  • Next Generation RET Inhibitors: Tyra Biosciences is developing novel RET inhibitors that target resistance mutations. Clinical trials are in early stages. Competitors include approved RET inhibitors such as selpercatinib (Retevmo) and pralsetinib (Gavreto). Market share data is currently unavailable.

Market Dynamics

industry overview logo Industry Overview

The oncology market is a large and rapidly growing market, driven by increasing cancer incidence and advancements in targeted therapies. The market is characterized by intense competition and a high degree of innovation.

Positioning

Tyra Biosciences is positioned as a precision oncology company focused on overcoming drug resistance. Its competitive advantage lies in its ability to design and develop novel small molecule inhibitors that target specific genetic alterations.

Total Addressable Market (TAM)

The TAM for targeted oncology therapies is estimated to be in the tens of billions of dollars. Tyra Biosciences is positioned to capture a portion of this market through the successful development and commercialization of its pipeline.

Upturn SWOT Analysis

Strengths

  • Novel drug discovery platform
  • Experienced management team
  • Strong intellectual property portfolio
  • Focus on overcoming drug resistance

Weaknesses

  • Limited clinical data
  • Dependence on successful clinical trial outcomes
  • High cash burn rate
  • No approved products

Opportunities

  • Partnerships with larger pharmaceutical companies
  • Expansion of pipeline into new cancer targets
  • Accelerated regulatory pathways
  • Growing demand for personalized cancer therapies

Threats

  • Clinical trial failures
  • Competition from established pharmaceutical companies
  • Regulatory hurdles
  • Patent challenges

Competitors and Market Share

competitor logo Key Competitors

  • LLY
  • BLU
  • AVXL

Competitive Landscape

Tyra Biosciences competes with both established pharmaceutical companies and other biotech companies developing targeted oncology therapies. It needs to demonstrate improved efficacy or safety compared to existing therapies.

Growth Trajectory and Initiatives

Historical Growth: Historical growth is characterized by preclinical research and clinical trial initiation.

Future Projections: Future growth is dependent on clinical trial success and potential regulatory approvals. Analyst estimates vary based on clinical data and market potential.

Recent Initiatives: Recent initiatives include advancing TYRA-300 into later-stage clinical trials and expanding the RET inhibitor program.

Summary

Tyra Biosciences is a clinical-stage biotech company focused on developing precision oncology therapies. Its strength lies in its novel drug discovery platform and experienced management team. The company faces risks associated with clinical trial outcomes and competition. Successful clinical trials and potential partnerships could drive future growth.

Peer Comparison

Sources and Disclaimers

Data Sources:

  • Company website
  • SEC filings
  • Analyst reports

Disclaimers:

This analysis is for informational purposes only and does not constitute investment advice. Information is based on available public data and may be subject to change.

Upturn AI SummarizationUpturn AI Summarization AI Summarization is directionally correct and might not be accurate.

Upturn AI SummarizationUpturn AI Summarization Summarized information shown could be a few years old and not current.

Upturn AI SummarizationUpturn AI Summarization Fundamental Rating based on AI could be based on old data.

Upturn AI SummarizationUpturn AI Summarization AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.

About Tyra Biosciences Inc

Exchange NASDAQ
Headquaters Carlsbad, CA, United States
IPO Launch date 2021-09-15
Co-Founder, President, CEO, Secretary, Treasurer & Director Dr. Todd Harris Ph.D.
Sector Healthcare
Industry Biotechnology
Full time employees 60
Full time employees 60

Tyra Biosciences, Inc., a clinical-stage biotechnology company, develops precision medicines for fibroblast growth factor receptor (FGFR) biology in the United States. The company offers SNÅP, a precision medicine platform that enables drug design through iterative molecular snapshots to predict genetic alterations for developing therapies targeting oncology and genetically defined conditions. Its lead product candidate is TYRA-300, which is in clinical trials for the treatment of patients with metastatic urothelial carcinoma and other solid tumors. The company is also developing TYRA-300 for skeletal conditions, including achondroplasia, hypochondroplasia, thanatophoric dysplasia, and other FGFR3-driven genetic syndromes; TYRA-200, a candidate in clinical trial for bile duct and solid tumors; and TYRA-430 for the treatment of hepatocellular carcinoma. The company was incorporated in 2018 and is headquartered in Carlsbad, California.