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VRTX 1-star rating from Upturn Advisory
Vertex Pharmaceuticals Inc (VRTX) company logo

Vertex Pharmaceuticals Inc (VRTX)

Vertex Pharmaceuticals Inc (VRTX) 1-star rating from Upturn Advisory
$463.86
Last Close (24-hour delay)
Profit since last BUY11.29%
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BUY since 58 days
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Upturn Advisory Summary

01/09/2026: VRTX (1-star) has a low Upturn Star Rating. Not recommended to BUY.

Upturn Star Rating

Upturn 1 star rating for performance

Not Recommended Performance

These Stocks/ETFs, based on Upturn Advisory, consistently fall short of market performance, signaling caution before investing.

Number of Analysts

5 star rating from financial analysts

34 Analysts rated it

Highly popular stock, broad analyst coverage, trusted insights, strong investor interest.

1 Year Target Price $500.4

1 Year Target Price $500.4

Analysts Price Target For last 52 week
$500.4 Target price
52w Low $362.5
Current$463.86
52w High $519.68

Analysis of Past Performance

Type Stock
Historic Profit -14.42%
Avg. Invested days 41
Today’s Advisory Consider higher Upturn Star rating
Upturn Star Rating upturn star rating icon
Upturn Advisory Performance Upturn Advisory Performance icon 3.0
Stock Returns Performance Upturn Returns Performance icon 1.0
Upturn Profits based on simulation icon Profits based on simulation
Upturn last close icon Last Close 01/09/2026

Key Highlights

Company Size Large-Cap Stock
Market Capitalization 118.93B USD
Price to earnings Ratio 32.69
1Y Target Price 500.4
Price to earnings Ratio 32.69
1Y Target Price 500.4
Volume (30-day avg) 34
Beta 0.31
52 Weeks Range 362.50 - 519.68
Updated Date 01/10/2026
52 Weeks Range 362.50 - 519.68
Updated Date 01/10/2026
Dividends yield (FY) -
Basic EPS (TTM) 14.19

Analyzing Revenue: Products, Geography and Growth

Revenue by Products

Product revenue - Year on Year

Revenue by Geography

Geography revenue - Year on Year

Earnings Date

Report Date -
When -
Estimate -
Actual -

Profitability

Profit Margin 31.35%
Operating Margin (TTM) 40.27%

Management Effectiveness

Return on Assets (TTM) 12.04%
Return on Equity (TTM) 22.31%

Valuation

Trailing PE 32.69
Forward PE 24.63
Enterprise Value 114714460544
Price to Sales(TTM) 10.14
Enterprise Value 114714460544
Price to Sales(TTM) 10.14
Enterprise Value to Revenue 9.79
Enterprise Value to EBITDA 24.61
Shares Outstanding 253718831
Shares Floating 252957675
Shares Outstanding 253718831
Shares Floating 252957675
Percent Insiders 0.13
Percent Institutions 97.81

About Vertex Pharmaceuticals Inc

Exchange NASDAQ
Headquaters Boston, MA, United States
IPO Launch date 1991-07-24
CEO, President & Director Dr. Reshma Kewalramani FASN, M.D.
Sector Healthcare
Industry Biotechnology
Full time employees 6100
Full time employees 6100

Vertex Pharmaceuticals Incorporated, a biotechnology company, engages in developing and commercializing therapies for treating cystic fibrosis (CF). It markets TRIKAFTA/KAFTRIO for people with CF with at least one F508del mutation for 2 years of age and older; ALYFTREK for the treatment for people with CF 6 years of age and older; SYMDEKO/SYMKEVI for treatment of patients with CF 6 years of age and older; ORKAMBI for CF patients 1 year or older; and KALYDECO for the treatment of patients with 1 month or older who have CF with ivacaftor. The company also develops CASGEVY for the treatment of sickle cell disease and transfusion-dependent beta thalassemia; JOURNAVX for the treatment of acute pain in adults; VX-522, a CFTR mRNA therapeutic designed to treat the underlying cause of CF, which is in Phase 1/2 clinical trial; inaxaplin for the treatment of APOL1-mediated kidney disease which is in single Phase 2; VX-880 and VX-264, treatment for Type 1 Diabetes; VX-670 for the treatment of myotonic dystrophy type 1; and VX-407, a small molecule corrector for the treatment of autosomal dominant polycystic kidney disease. Further, it sells the products to specialty pharmacy and specialty distributors in the United States, as well as retail pharmacies, hospitals, and clinics. Additionally, the company has collaborations with CRISPR Therapeutics AG.; Moderna, Inc.; and Entrada Therapeutics, Inc. Vertex Pharmaceuticals Incorporated was founded in 1989 and is headquartered in Boston, Massachusetts.