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Vertex Pharmaceuticals Inc (VRTX)

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Upturn Advisory Summary
01/09/2026: VRTX (1-star) has a low Upturn Star Rating. Not recommended to BUY.
1 Year Target Price $500.4
1 Year Target Price $500.4
| 14 | Strong Buy |
| 4 | Buy |
| 14 | Hold |
| 1 | Sell |
| 1 | Strong Sell |
Analysis of Past Performance
Type Stock | Historic Profit -14.42% | Avg. Invested days 41 | Today’s Advisory Consider higher Upturn Star rating |
Upturn Star Rating ![]() | Upturn Advisory Performance | Stock Returns Performance |
Key Highlights
Company Size Large-Cap Stock | Market Capitalization 118.93B USD | Price to earnings Ratio 32.69 | 1Y Target Price 500.4 |
Price to earnings Ratio 32.69 | 1Y Target Price 500.4 | ||
Volume (30-day avg) 34 | Beta 0.31 | 52 Weeks Range 362.50 - 519.68 | Updated Date 01/10/2026 |
52 Weeks Range 362.50 - 519.68 | Updated Date 01/10/2026 | ||
Dividends yield (FY) - | Basic EPS (TTM) 14.19 |
Analyzing Revenue: Products, Geography and Growth
Revenue by Products
Product revenue - Year on Year
Revenue by Geography
Geography revenue - Year on Year
Earnings Date
Report Date - | When - | Estimate - | Actual - |
Profitability
Profit Margin 31.35% | Operating Margin (TTM) 40.27% |
Management Effectiveness
Return on Assets (TTM) 12.04% | Return on Equity (TTM) 22.31% |
Valuation
Trailing PE 32.69 | Forward PE 24.63 | Enterprise Value 114714460544 | Price to Sales(TTM) 10.14 |
Enterprise Value 114714460544 | Price to Sales(TTM) 10.14 | ||
Enterprise Value to Revenue 9.79 | Enterprise Value to EBITDA 24.61 | Shares Outstanding 253718831 | Shares Floating 252957675 |
Shares Outstanding 253718831 | Shares Floating 252957675 | ||
Percent Insiders 0.13 | Percent Institutions 97.81 |
About Vertex Pharmaceuticals Inc
Exchange NASDAQ | Headquaters Boston, MA, United States | ||
IPO Launch date 1991-07-24 | CEO, President & Director Dr. Reshma Kewalramani FASN, M.D. | ||
Sector Healthcare | Industry Biotechnology | Full time employees 6100 | Website https://www.vrtx.com |
Full time employees 6100 | Website https://www.vrtx.com | ||
Vertex Pharmaceuticals Incorporated, a biotechnology company, engages in developing and commercializing therapies for treating cystic fibrosis (CF). It markets TRIKAFTA/KAFTRIO for people with CF with at least one F508del mutation for 2 years of age and older; ALYFTREK for the treatment for people with CF 6 years of age and older; SYMDEKO/SYMKEVI for treatment of patients with CF 6 years of age and older; ORKAMBI for CF patients 1 year or older; and KALYDECO for the treatment of patients with 1 month or older who have CF with ivacaftor. The company also develops CASGEVY for the treatment of sickle cell disease and transfusion-dependent beta thalassemia; JOURNAVX for the treatment of acute pain in adults; VX-522, a CFTR mRNA therapeutic designed to treat the underlying cause of CF, which is in Phase 1/2 clinical trial; inaxaplin for the treatment of APOL1-mediated kidney disease which is in single Phase 2; VX-880 and VX-264, treatment for Type 1 Diabetes; VX-670 for the treatment of myotonic dystrophy type 1; and VX-407, a small molecule corrector for the treatment of autosomal dominant polycystic kidney disease. Further, it sells the products to specialty pharmacy and specialty distributors in the United States, as well as retail pharmacies, hospitals, and clinics. Additionally, the company has collaborations with CRISPR Therapeutics AG.; Moderna, Inc.; and Entrada Therapeutics, Inc. Vertex Pharmaceuticals Incorporated was founded in 1989 and is headquartered in Boston, Massachusetts.

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