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XRTX
Upturn stock rating

XORTX Therapeutics Inc (XRTX)

Upturn stock rating
$1.1
Last Close (24-hour delay)
Profit since last BUY25%
upturn advisory
Consider higher Upturn Star rating
BUY since 5 days
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Upturn Stock info Stock price based on last close
*as per simulation
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Time period over
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Upturn Advisory Summary

10/17/2025: XRTX (1-star) has a low Upturn Star Rating. Not recommended to BUY.

Upturn Star Rating

rating

Not Recommended Performance

These Stocks/ETFs, based on Upturn Advisory, consistently fall short of market performance, signaling caution before investing.

Number of Analysts

rating

1 Analysts rated it

Very few follow this stock; limited insights, higher-risk early investing.

1 Year Target Price $13.74

1 Year Target Price $13.74

Analysts Price Target For last 52 week
$13.74 Target price
52w Low $0.66
Current$1.1
52w High $1.99

Analysis of Past Performance

Type Stock
Historic Profit -3.39%
Avg. Invested days 17
Today’s Advisory Consider higher Upturn Star rating
Upturn Star Rating upturn star rating icon
Upturn Advisory Performance Upturn Advisory Performance 3.0
Stock Returns Performance Upturn Returns Performance 1.0
Upturn Profits based on simulation Profits based on simulation
Upturn Profits based on simulation Last Close 10/17/2025

Key Highlights

Company Size Small-Cap Stock
Market Capitalization 5.73M USD
Price to earnings Ratio -
1Y Target Price 13.74
Price to earnings Ratio -
1Y Target Price 13.74
Volume (30-day avg) 1
Beta -0.18
52 Weeks Range 0.66 - 1.99
Updated Date 10/18/2025
52 Weeks Range 0.66 - 1.99
Updated Date 10/18/2025
Dividends yield (FY) -
Basic EPS (TTM) -0.46

Earnings Date

Report Date -
When -
Estimate -
Actual -

Profitability

Profit Margin -
Operating Margin (TTM) -

Management Effectiveness

Return on Assets (TTM) -42.15%
Return on Equity (TTM) -79.44%

Valuation

Trailing PE -
Forward PE 0.96
Enterprise Value 3204483
Price to Sales(TTM) -
Enterprise Value 3204483
Price to Sales(TTM) -
Enterprise Value to Revenue -
Enterprise Value to EBITDA 0.09
Shares Outstanding 5212218
Shares Floating 5069038
Shares Outstanding 5212218
Shares Floating 5069038
Percent Insiders 2.63
Percent Institutions 4.64

ai summary icon Upturn AI SWOT

XORTX Therapeutics Inc

stock logo

Company Overview

overview logo History and Background

XORTX Therapeutics Inc. is a biopharmaceutical company focused on developing therapies to treat progressive kidney disease, with a focus on orphan diseases. Founded to address unmet needs in kidney health, the company is developing treatments for diseases such as focal segmental glomerulosclerosis (FSGS).

business area logo Core Business Areas

  • Drug Development: XORTX focuses on developing and commercializing therapies for progressive kidney disease, specifically treatments targeting purine metabolism and uric acid production.

leadership logo Leadership and Structure

The leadership team consists of experienced professionals in drug development, clinical trials, and regulatory affairs. The organizational structure includes departments for research and development, clinical operations, and corporate management.

Top Products and Market Share

overview logo Key Offerings

  • XRx-008: XRx-008 is XORTX's lead product candidate, a selective xanthine oxidase inhibitor (sXOI) being developed for the treatment of ADPKD and other progressive kidney diseases. Market share data is not publicly available as it is still in development stage. Competitors include companies developing therapies for ADPKD.

Market Dynamics

industry overview logo Industry Overview

The biopharmaceutical industry focused on kidney disease is characterized by a growing need for effective therapies, especially for progressive and rare kidney conditions. There is a rising prevalence of chronic kidney disease worldwide, driving the demand for new treatment options.

Positioning

XORTX is positioned as a company focused on developing innovative therapies for progressive kidney disease, with a focus on purine metabolism. Its competitive advantage lies in its targeted approach and potential to address unmet medical needs.

Total Addressable Market (TAM)

The market for kidney disease therapies is substantial and growing, estimated to be in the billions of dollars. XORTX is positioned to capture a share of this market with its pipeline of product candidates.

Upturn SWOT Analysis

Strengths

  • Focus on unmet needs in kidney disease
  • Proprietary technology and intellectual property
  • Experienced management team

Weaknesses

  • Limited financial resources
  • Dependence on successful clinical trials
  • Small company size compared to competitors

Opportunities

  • Potential for orphan drug designation
  • Partnerships and collaborations with larger pharmaceutical companies
  • Expansion of product pipeline

Threats

  • Regulatory hurdles
  • Competition from established pharmaceutical companies
  • Failure of clinical trials

Competitors and Market Share

competitor logo Key Competitors

  • VRTX
  • ALNY

Competitive Landscape

XORTX is disadvantaged compared to major pharmaceutical companies due to smaller size and resources. However, it has an advantage of focusing on one target, whereas others have many things to consider.

Growth Trajectory and Initiatives

Historical Growth: Growth is related to the successful advancement of clinical trials. There has not been any revenue history to speak of as of yet.

Future Projections: Future growth depends on successful clinical trials and potential regulatory approvals. Analyst estimates suggest potential upside if XRx-008 is successful.

Recent Initiatives: Recent initiatives include advancing XRx-008 through clinical trials and seeking partnerships.

Summary

XORTX Therapeutics Inc. is a biopharmaceutical company focused on kidney diseases, particularly ADPKD. As a small company with limited resources, they are highly dependent on successful clinical trial outcomes for XRx-008 and future funding. The company faces competition from larger, established pharmaceutical companies, making partnerships crucial. While focused on an unmet need, the company's future growth hinges on navigating regulatory hurdles and achieving positive clinical trial results.

Peer Comparison

Sources and Disclaimers

Data Sources:

  • Company website
  • SEC filings
  • Analyst reports

Disclaimers:

The information provided is for informational purposes only and should not be considered investment advice. The analysis is based on publicly available information and may not be complete or accurate. Investing in XORTX Therapeutics Inc. involves significant risks, including the risk of loss.

Upturn AI Summarization AI Summarization is directionally correct and might not be accurate.

Upturn AI Summarization Summarized information shown could be a few years old and not current.

Upturn AI Summarization Fundamental Rating based on AI could be based on old data.

Upturn AI Summarization AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.

About XORTX Therapeutics Inc

Exchange NASDAQ
Headquaters Calgary, AB, Canada
IPO Launch date 2018-11-28
Founder, CEO, President & Director Dr. Allen Warren Davidoff Ph.D.
Sector Healthcare
Industry Biotechnology
Full time employees -
Full time employees -

XORTX Therapeutics Inc., a late-stage clinical pharmaceutical company, engages in the development and commercialization of therapies to treat gout and progressive kidney disease. Its drug development programs include XRx-026, which is in the third phase for the treatment of gout; XRx-008, which is in the second phase to treat autosomal dominant polycystic kidney disease; XRx-101, which is in the second phase to treat acute kidney injury associated with respiratory virus infection; and XRX-225, which is in the preclinical stage for the treatment of type 2 diabetic nephropathy. It has a license agreement with the University of Florida Research Foundation, Inc. for the use of uric acid lowering agent to treat insulin resistance. The company is based in Calgary, Canada.