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22nd Century Group Inc (XXII)


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Upturn Advisory Summary
10/15/2025: XXII (1-star) is currently NOT-A-BUY. Pass it for now.
1 Year Target Price $720
1 Year Target Price $720
0 | Strong Buy |
0 | Buy |
1 | Hold |
0 | Sell |
0 | Strong Sell |
Analysis of Past Performance
Type Stock | Historic Profit 0% | Avg. Invested days 0 | Today’s Advisory PASS |
Upturn Star Rating ![]() | Upturn Advisory Performance ![]() | Stock Returns Performance ![]() |
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Key Highlights
Company Size Small-Cap Stock | Market Capitalization 5.60M USD | Price to earnings Ratio - | 1Y Target Price 720 |
Price to earnings Ratio - | 1Y Target Price 720 | ||
Volume (30-day avg) 1 | Beta 1.95 | 52 Weeks Range 1.44 - 434.70 | Updated Date 10/17/2025 |
52 Weeks Range 1.44 - 434.70 | Updated Date 10/17/2025 | ||
Dividends yield (FY) - | Basic EPS (TTM) 1500.24 |
Analyzing Revenue: Products, Geography and Growth
Revenue by Products
Product revenue - Year on Year
Earnings Date
Report Date - | When - | Estimate - | Actual - |
Profitability
Profit Margin -75.12% | Operating Margin (TTM) -133.8% |
Management Effectiveness
Return on Assets (TTM) -34.67% | Return on Equity (TTM) -616.13% |
Valuation
Trailing PE - | Forward PE - | Enterprise Value 8508831 | Price to Sales(TTM) 0.26 |
Enterprise Value 8508831 | Price to Sales(TTM) 0.26 | ||
Enterprise Value to Revenue 0.96 | Enterprise Value to EBITDA -0.47 | Shares Outstanding 3781492 | Shares Floating 3450693 |
Shares Outstanding 3781492 | Shares Floating 3450693 | ||
Percent Insiders 1.91 | Percent Institutions 0.88 |
Upturn AI SWOT
22nd Century Group Inc

Company Overview
History and Background
22nd Century Group, Inc. was founded in 1998. Initially focused on tobacco harm reduction, it has evolved to include plant biotechnology, focusing on reduced nicotine tobacco, hemp/cannabis, and sustainable agriculture.
Core Business Areas
- Tobacco: Developing and commercializing reduced nicotine content (RNC) cigarettes, targeting the FDA's proposed nicotine cap in cigarettes. Also engaged in research on tobacco plant characteristics.
- Hemp/Cannabis: Developing and commercializing hemp/cannabis varieties with improved agronomic traits and cannabinoid profiles.
- Contract Manufacturing: Provides contract manufacturing of CBD products and cigarettes
Leadership and Structure
James A. Mish is the Chief Executive Officer. The company has a board of directors overseeing its operations. Organizational structure is based on its key divisions, with dedicated teams for tobacco, hemp/cannabis, and research & development.
Top Products and Market Share
Key Offerings
- VLN Cigarettes: Very Low Nicotine cigarettes, positioned as a potential harm reduction product pending FDA authorization. Limited market share currently. Competitors include major tobacco companies like Philip Morris International (PM) and British American Tobacco (BTI).
- Hemp and Cannabis Genetics: Developing and licensing proprietary hemp and cannabis genetics for various applications. Revenue and market share still developing as the business is relatively new. Competitors include companies like Cronos Group (CRON) and Canopy Growth Corporation (CGC).
Market Dynamics
Industry Overview
The tobacco industry is facing increasing regulatory pressure to reduce nicotine levels. The hemp/cannabis industry is rapidly evolving with varying legal landscapes across different regions.
Positioning
22nd Century Group aims to disrupt the tobacco industry with its reduced nicotine cigarettes and establish a presence in the hemp/cannabis market with its proprietary genetics. Their competitive advantage lies in their intellectual property and scientific expertise.
Total Addressable Market (TAM)
The tobacco harm reduction market is potentially in the billions. The legal cannabis market has an even higher TAM, projected at $50 billion in the US by 2026. 22nd Century Group is positioning itself to capture market share in these growing sectors.
Upturn SWOT Analysis
Strengths
- Proprietary technology for reduced nicotine tobacco
- Scientific expertise in plant biotechnology
- Intellectual property portfolio
- FDA authorization potential for VLN cigarettes
Weaknesses
- Limited commercialization success to date
- High operating expenses
- Dependence on regulatory approvals
- History of net losses
Opportunities
- FDA mandate for reduced nicotine in cigarettes
- Expansion into the legal cannabis market
- Partnerships with major tobacco companies
- Growing demand for tobacco harm reduction products
Threats
- Resistance from major tobacco companies
- Regulatory uncertainty in the cannabis industry
- Competition from other tobacco harm reduction products
- Potential changes in government regulations
Competitors and Market Share
Key Competitors
- PM
- MO
- BTI
- CRON
- CGC
- SMG
Competitive Landscape
22nd Century Group faces intense competition from established tobacco companies with vast resources and brand recognition. It also competes with other cannabis companies in the rapidly growing cannabis market. XXII competitive advantage is its intellectual property around VLN tobacco.
Major Acquisitions
Hemp Rise, LLC
- Year: 2020
- Acquisition Price (USD millions): 15
- Strategic Rationale: Expanded 22nd Century Group's presence in the hemp/cannabis market.
Growth Trajectory and Initiatives
Historical Growth: Historical growth has been limited, with fluctuating revenues and consistent net losses.
Future Projections: Future growth depends heavily on regulatory approvals and successful commercialization of VLN cigarettes and hemp/cannabis products. Analyst estimates vary widely.
Recent Initiatives: Focus on securing FDA authorization for VLN, expanding hemp/cannabis operations, and exploring strategic partnerships.
Summary
22nd Century Group is a high-risk, high-reward investment. Its success hinges on regulatory approvals and successful commercialization of its products. The company has promising technology but faces strong competition and financial challenges. Investors should carefully consider the risks before investing in XXII.
Peer Comparison
Sources and Disclaimers
Data Sources:
- Company Website
- SEC Filings
- Analyst Reports
- Industry Publications
Disclaimers:
This analysis is for informational purposes only and should not be considered investment advice. Financial data is based on available information and may be subject to change. Market share data are estimates and may not be precise.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About 22nd Century Group Inc
Exchange NASDAQ | Headquaters Mocksville, NC, United States | ||
IPO Launch date 2011-01-26 | President & CEO Mr. Lawrence D. Firestone | ||
Sector Consumer Defensive | Industry Tobacco | Full time employees 56 | Website https://www.xxiicentury.com |
Full time employees 56 | Website https://www.xxiicentury.com |
22nd Century Group, Inc., a tobacco products company, manufactures, distributes, and sells proprietary new reduced nicotine tobacco products in the United States. The company offers reduced nicotine content tobacco and very low nicotine combustible cigarette products. It also provides contract manufacturing services for conventional combustible tobacco products for third-party brands, as well as turnkey contract manufacturing of cigarettes and filtered cigars for other established tobacco brands. 22nd Century Group, Inc. was founded in 1998 and is headquartered in Mocksville, North Carolina.

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