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ZVRA
Upturn stock ratingUpturn stock rating

Zevra Therapeutics Inc. (ZVRA)

Upturn stock ratingUpturn stock rating
$8.9
Last Close (24-hour delay)
Profit since last BUY9.34%
upturn advisory
SELL
SELL since 1 day
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  • SELL Advisory (Loss)​
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Upturn Stock infoUpturn Stock info Stock price based on last close
*as per simulation
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Upturn Advisory Summary

08/14/2025: ZVRA (4-star) is a SELL. SELL since 1 days. Profits (9.34%). Updated daily EoD!

Upturn Star Rating

rating

Above Average Performance

These Stocks/ETFs, based on Upturn Advisory, frequently surpass the market, reflecting reliable and trustworthy advice.

Number of Analysts

rating

7 Analysts rated it

Limited analyst coverage, niche firm, research info may be scarce.

1 Year Target Price $23.22

1 Year Target Price $23.22

Analysts Price Target For last 52 week
$23.22 Target price
52w Low $6.19
Current$8.9
52w High $13.16

Analysis of Past Performance

Type Stock
Historic Profit 32.34%
Avg. Invested days 44
Today’s Advisory SELL
Upturn Star Rating Upturn stock ratingUpturn stock rating
Upturn Advisory Performance Upturn Advisory Performance 3.0
Stock Returns Performance Upturn Returns Performance 3.0
Upturn Profits based on simulationUpturn Profits based on simulation Profits based on simulation
Upturn Profits based on simulationUpturn Profits based on simulation Last Close 08/14/2025

Key Highlights

Company Size Small-Cap Stock
Market Capitalization 519.44M USD
Price to earnings Ratio -
1Y Target Price 23.22
Price to earnings Ratio -
1Y Target Price 23.22
Volume (30-day avg) 7
Beta 1.87
52 Weeks Range 6.19 - 13.16
Updated Date 08/14/2025
52 Weeks Range 6.19 - 13.16
Updated Date 08/14/2025
Dividends yield (FY) -
Basic EPS (TTM) -0.25

Analyzing Revenue: Products, Geography and Growth

Revenue by Products

Earnings Date

Report Date 2025-08-19
When -
Estimate 2.19
Actual -0.06

Profitability

Profit Margin 4.26%
Operating Margin (TTM) -47.64%

Management Effectiveness

Return on Assets (TTM) -18.85%
Return on Equity (TTM) 3.53%

Valuation

Trailing PE -
Forward PE 17.48
Enterprise Value 379109043
Price to Sales(TTM) 8.38
Enterprise Value 379109043
Price to Sales(TTM) 8.38
Enterprise Value to Revenue 6.11
Enterprise Value to EBITDA 10.4
Shares Outstanding 54679600
Shares Floating 47234311
Shares Outstanding 54679600
Shares Floating 47234311
Percent Insiders 0.69
Percent Institutions 62.1

ai summary icon Upturn AI SWOT

Zevra Therapeutics Inc.

stock logo

Company Overview

overview logo History and Background

Zevra Therapeutics, formerly KemPharm, was founded in 2006. The company initially focused on prodrugs and has evolved to focus on rare diseases. They have rebranded to reflect their shift in focus.

business area logo Core Business Areas

  • Rare Disease Therapeutics: Focuses on developing and commercializing therapies for rare diseases, including those affecting the central nervous system.

leadership logo Leadership and Structure

Richard A. Pascoe serves as the Chief Executive Officer. The company has a typical organizational structure for a publicly traded pharmaceutical company, with various departments focused on research and development, commercialization, and administration.

Top Products and Market Share

overview logo Key Offerings

  • OLPRUVA (sodium phenylbutyrate): Indicated for use as a nitrogen-binding agent for long-term management of urea cycle disorders (UCDs). Market share is difficult to ascertain precisely, but Zevra is actively competing with established therapies. Competitors include Horizon Therapeutics (Ravicti, Buphenyl).
  • KEMDYSA (methylphenidate hydrochloride) Chewable Tablets: KEMDYSA is a treatment for attention deficit hyperactivity disorder (ADHD) in patients 6 years and older. It is sold by another company under agreement. Competitors include other ADHD medications like Adderall, Concerta, and Ritalin.

Market Dynamics

industry overview logo Industry Overview

The rare disease therapeutics market is growing rapidly, driven by increased awareness, orphan drug designations, and advancements in genetic research. This sector faces challenges such as high development costs and complex regulatory pathways.

Positioning

Zevra is positioning itself as a player in the rare disease space, focusing on areas with unmet medical needs. Their competitive advantage lies in their ability to acquire and develop therapies for niche markets.

Total Addressable Market (TAM)

The global rare disease market is projected to reach hundreds of billions of dollars. Zevra is positioned to capture a share of this TAM by focusing on specific rare diseases and developing targeted therapies.

Upturn SWOT Analysis

Strengths

  • Focus on rare diseases
  • Experienced management team
  • Established commercial infrastructure
  • Growing revenue

Weaknesses

  • Limited product pipeline
  • Dependence on key products
  • Small market capitalization
  • Potential for regulatory setbacks

Opportunities

  • Expansion into new rare disease areas
  • Acquisition of additional product candidates
  • Strategic partnerships
  • Potential for orphan drug designations

Threats

  • Competition from larger pharmaceutical companies
  • Generic erosion of key products
  • Changes in regulatory landscape
  • Economic downturn

Competitors and Market Share

competitor logo Key Competitors

  • Horizon Therapeutics (HZNP)

Competitive Landscape

Zevra is a smaller player compared to larger pharmaceutical companies. Their competitive advantage lies in focusing on niche rare disease markets.

Major Acquisitions

Azevan Pharmaceuticals, Inc.

  • Year: 2023
  • Acquisition Price (USD millions): 15
  • Strategic Rationale: The acquisition of Azevan Pharmaceuticals, Inc. added arimoclomol, a Phase 2b asset with orphan drug and rare pediatric disease designations, being developed for Niemann-Pick disease type C (NPC), to Zevrau2019s development pipeline.

Growth Trajectory and Initiatives

Historical Growth: Historical growth trends would need to be extracted from Zevra's financial statements over the past several years.

Future Projections: Future projections are typically based on analyst estimates and company guidance. These estimates can be found on financial websites.

Recent Initiatives: Recent initiatives include the acquisition of new product candidates and efforts to expand commercial reach.

Summary

Zevra Therapeutics is a growing pharmaceutical company focused on rare diseases. Its revenue streams and key products show promise. The small market cap presents challenges as they compete with larger companies with deeper pockets. Continued pipeline development and strategic acquisitions are critical for sustained growth.

Peer Comparison

Sources and Disclaimers

Data Sources:

  • Company SEC Filings (10-K, 10-Q)
  • Company Investor Relations Website
  • Third-Party Financial Data Providers
  • Industry News and Reports

Disclaimers:

The information provided is for informational purposes only and should not be construed as investment advice. Market share estimates are approximate and subject to change. Actual results may vary.

Upturn AI SummarizationUpturn AI Summarization AI Summarization is directionally correct and might not be accurate.

Upturn AI SummarizationUpturn AI Summarization Summarized information shown could be a few years old and not current.

Upturn AI SummarizationUpturn AI Summarization Fundamental Rating based on AI could be based on old data.

Upturn AI SummarizationUpturn AI Summarization AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.

About Zevra Therapeutics Inc.

Exchange NASDAQ
Headquaters Celebration, FL, United States
IPO Launch date 2015-04-16
President, CEO & Director Mr. Neil F. McFarlane
Sector Healthcare
Industry Biotechnology
Full time employees 59
Full time employees 59

Zevra Therapeutics, Inc., a commercial-stage company, focuses on addressing unmet needs for the treatment of rare diseases in the United States. The company develops its products through Ligand Activated Technology platform. Its lead product candidate is KP1077, consisting of KP1077IH, which is under Phase 2 clinical trial for the treatment of idiopathic hypersomnia, and KP1077N, which is under Phase 1/2 clinical trial to treat narcolepsy. The company is also developing Celiprolol, a prodrug product candidate that is under Phase 3 clinical trial for the treatment of vascular Ehlers Danlos syndrome. In addition, it offers AZSTARYS, a once-daily treatment for attention deficit and hyperactivity disorder in patients aged six years and older; OLPRUVA to treat urea cycle disorders; and MIPLYFFA for the treatment of niemann pick disease type C, an ultra-rare neurodegenerative lysosomal storage disorder. The company has collaboration and license agreement with Commave Therapeutics SA to develop, manufacture and commercialize the company's product candidates containing SDX and d-methylphenidate; and license agreement with Acer and Relief Therapeutics, Inc. to develop and commercialize rights for OLPRUVA. The company was formerly known as KemPharm, Inc. and changed its name to Zevra Therapeutics, Inc. in February 2023. Zevra Therapeutics, Inc. was incorporated in 2006 and is headquartered in Celebration, Florida.