iShares Genomics Immunology and Healthcare ETF(IDNA)

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EXPLORE ADVISORIES AND THEIR HISTORY
QUALITY SIGNAL RECENCY
2-STAR RATING
Consider higher Upturn Star rating
BUY for 90 days
PROFIT SINCE LAST BUY
+39.46% ▲
LAST CLOSE
$43.47
10/28/2026
(24-hour delay)

Advisory History & Simulated Performance *

*as per simulation (see disclosures)
  • ALL
  • 1Y
  • 1M
  • 1W
  • BUY Advisory
  • SELL Advisory (Profit)
  • SELL Advisory (Loss)
  • Profit
  • Loss
  • PASS (Skip)
Upturn Stock price based on last close iconStock price based on last close
Simulated performance—not actual client returns. Excludes advisory subscription fees, trading commissions, and taxes, which would reduce returns. Results depend on calculation assumptions and do not guarantee future outcomes. See Disclosures for full methodology, assumptions, and limitations.

Advisory Performance History (Simulated)Advisory Performance History info

Simulated performance—not actual client returns. Excludes advisory subscription fees, trading commissions, and taxes, which would reduce returns. Results depend on calculation assumptions and do not guarantee future outcomes. See Disclosures for full methodology, assumptions, and limitations.

Upturn Advisory & Investor View for IDNA

10/28/2026: IDNA (2-star) has a low Upturn Star Rating. Not recommended to BUY.

IDNA provides targeted exposure to global companies leading the way in genomics, immunology, and bioengineering. Its main strengths are its low-cost index-based approach and the institutional oversight provided by iShares, making it a competitive choice for thematic investors. It is best used as a high-growth satellite position within a diversified portfolio. Key risks include significant volatility, regulatory uncertainty, and the speculative nature of pre-revenue biotechnology firms. It is most suitable for long-term growth investors who can handle sector-specific swings and understand the binary risks associated with pharmaceutical development.

How to Read the Upturn Advisory

The Upturn Star Rating and the current BUY, SELL, or PASS advisory are generated by Upturn’s AI advisory engine based on proprietary signal analysis, price behavior, advisory history, and historical signal performance.

ETF holdings, costs, diversification, valuation, risks, and market conditions provide supporting context about the fund.

Investor Fit

Investor styleFitWhy
Growth investorStrong fitThe fund focuses on disruptive technologies in healthcare, which are core holdings for long-term growth portfolios.
Momentum investorStrong fit while signal remains positiveBiotech innovation cycles often create strong momentum trends, making this a fit for traders during positive industry sentiment.
Value investorWeak fitThe portfolio contains many high-multiple, pre-revenue biotech firms that rarely meet standard value investing metrics.
Dividend/Income investorWeak fitMost companies in the genomics and immunology space prioritize R&D over dividend payments.
Low-risk investorWeak fitHigh exposure to speculative biotech development makes this fund unsuitable for risk-averse investors.

Investor Profile

Ideal Investor Profile

Growth-oriented investors seeking thematic exposure to healthcare innovation who have a high tolerance for risk and a multi-year investment horizon.

Suitability

Best for long-term investors aiming to add a thematic satellite position to a core portfolio, rather than for active traders or those needing steady income.

Risk Profile

Risk factorLevelWhy it matters
VolatilityHighThe biotechnology sector is prone to sharp price swings based on clinical trial results and regulatory outcomes.
Market riskMedium / highBroader economic downturns can significantly impact the valuation of high-growth, innovative equity sectors.
ConcentrationMediumThe fund is limited to the genomics and immunology niche, lacking the diversification of a total healthcare index.
Tracking/expenseLowiShares products generally track their indices with high precision and low tracking error.
LiquidityMediumSmaller-cap biotech holdings can face liquidity constraints during periods of market stress.
Business/sector qualityMedium / highThe success of many underlying holdings is binary, depending on FDA approval and successful clinical outcomes.

Risk Analysis

Volatility

IDNA exhibits significantly higher volatility than the S&P 500, reflective of its concentration in speculative, development-stage healthcare companies.

Market Risk

The fund is sensitive to interest rate fluctuations and regulatory policy, as the underlying firms often require external financing to continue research.

What the ETF Owns

Exposure TypeExposureWeight (%)Retail Investor Read
IndustryBiotechnology65This sector is the primary driver of the fund, capturing companies involved in genomic research and immunological therapies.
IndustryPharmaceuticals25Large and mid-cap pharma exposure provides stability and commercialization scale for innovative health technologies.
IndustryHealthcare Technology/Life Sciences8These firms provide the tools, diagnostics, and data infrastructure essential for genomic and immunological breakthroughs.
Cash/collateralCash and Cash Equivalents2Minimal cash reserves are held for liquidity and rebalancing purposes.

Price Behavior

Hockey-Stick Growth
PRICE PATH

Hockey-Stick Growth

The stock demonstrates a Hockey-Stick Growth price path pattern.

Smooth
PRICE STABILITY

Smooth

The stock has moved along a generally orderly path with only modest fluctuations.

Analysis of Past Performance

Type ETF
Historic Profit 58.15%
Avg. Invested days 62
Today’s Advisory Consider higher Upturn Star rating
Upturn Advisory Rating upturn star rating icon
Upturn Advisory Performance Upturn Advisory Performance icon 2.0
ETF Returns Performance Upturn Returns Performance icon 5.0
Upturn Profits based on simulation icon Profits based on simulation
Upturn last close icon Last Close 10/28/2026
Form CRS provides a relationship summary of our automated advisory services, flat subscription fees, and conflicts of interest. Form ADV Part 2A brochure contains complete details on services, billing, and disclosures. If any summary differs from our current regulatory filings, the filed Form ADV controls.