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Horizon Kinetics Medical ETF (MEDX)

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Upturn Advisory Summary
01/09/2026: MEDX (2-star) has a low Upturn Star Rating. Not recommended to BUY.
Analysis of Past Performance
Type ETF | Historic Profit 31.85% | Avg. Invested days 74 | Today’s Advisory Consider higher Upturn Star rating |
Upturn Star Rating ![]() | Upturn Advisory Performance | ETF Returns Performance |
Key Highlights
Volume (30-day avg) - | Beta 0.49 | 52 Weeks Range 23.46 - 31.41 | Updated Date 06/30/2025 |
52 Weeks Range 23.46 - 31.41 | Updated Date 06/30/2025 |
Upturn AI SWOT
Horizon Kinetics Medical ETF
ETF Overview
Overview
The Horizon Kinetics Medical ETF (MEDX) is an actively managed exchange-traded fund focused on identifying and investing in companies within the healthcare sector that are poised for significant growth. The fund's strategy centers on identifying companies with innovative products, services, or technologies that address unmet medical needs or offer substantial improvements over existing solutions. Its asset allocation is primarily concentrated in equities, with a particular emphasis on small- and mid-cap companies that may offer higher growth potential but also carry increased risk.
Reputation and Reliability
Horizon Kinetics is an investment advisor focused on identifying and investing in companies with differentiated business models and significant growth potential. While not a massive issuer by AUM compared to giants like Vanguard or BlackRock, it has a dedicated following among investors seeking actively managed, concentrated strategies.
Management Expertise
The ETF is managed by Horizon Kinetics LLC, a firm known for its fundamental research-driven approach to identifying unique investment opportunities. The management team typically emphasizes deep dives into company operations, competitive landscapes, and disruptive potential within their respective industries.
Investment Objective
Goal
The primary investment goal of the Horizon Kinetics Medical ETF is to achieve long-term capital appreciation by investing in a concentrated portfolio of companies operating in the medical field.
Investment Approach and Strategy
Strategy: This ETF does not aim to track a specific index. Instead, it employs an active management strategy, where the portfolio managers conduct in-depth fundamental research to select individual securities they believe will outperform.
Composition The ETF is primarily composed of equities, focusing on companies within the biotechnology, pharmaceutical, medical devices, and healthcare services sub-sectors. The portfolio is typically concentrated, meaning it holds a relatively smaller number of carefully selected stocks.
Market Position
Market Share: Data on the specific market share of the Horizon Kinetics Medical ETF within the broader healthcare ETF market is not readily available and can fluctuate. Its market share is likely small compared to broad-market healthcare ETFs.
Total Net Assets (AUM): As of recent data, the Total Net Assets (AUM) for the Horizon Kinetics Medical ETF typically range in the tens to low hundreds of millions of US dollars, indicating a niche market position.
Competitors
Key Competitors
- iShares U.S. Healthcare ETF (IYH)
- Health Care Select Sector SPDR Fund (XLV)
- Vanguard Health Care ETF (VHT)
Competitive Landscape
The US healthcare ETF market is highly competitive and dominated by large, passively managed index funds like XLV and VHT, which offer broad diversification and low expense ratios. MEDX operates in a niche with its actively managed, concentrated approach, appealing to investors seeking potentially higher alpha but with higher risk and potentially higher fees. Its advantage lies in its focused strategy and potential for manager skill to drive outperformance, while its disadvantage is its lack of broad diversification and the inherent risks of active management and concentration.
Financial Performance
Historical Performance: Historical performance data for MEDX shows variable returns, influenced by its concentrated and actively managed nature. Investors should review the ETF's performance over various timeframes (1-year, 3-year, 5-year, inception-to-date) to understand its track record, noting periods of both outperformance and underperformance relative to broader healthcare indices.
Benchmark Comparison: As an actively managed fund, MEDX's performance is benchmarked against broader healthcare indices, though its concentrated holdings may lead to significant divergence. Comparisons should be made against relevant healthcare benchmarks to assess the manager's ability to add value.
Expense Ratio: The expense ratio for the Horizon Kinetics Medical ETF is typically higher than passive index ETFs, reflecting the costs associated with active management. This is usually in the range of 0.70% to 1.00%.
Liquidity
Average Trading Volume
The ETF's average trading volume can vary, but it is generally lower than that of the largest healthcare ETFs, indicating moderate liquidity.
Bid-Ask Spread
The bid-ask spread for MEDX can be wider than that of highly liquid ETFs, meaning there might be a slightly higher cost associated with frequent trading.
Market Dynamics
Market Environment Factors
The ETF is influenced by broad economic conditions, regulatory changes impacting the healthcare industry, advancements in medical technology, patent expirations, and shifts in healthcare policy. Growth prospects are tied to innovation and demand for healthcare services and products.
Growth Trajectory
The growth trajectory of MEDX is dependent on the success of its specific stock selections and the overall performance of the healthcare sector. Changes in strategy would involve adjustments to its holdings based on evolving market conditions and the manager's outlook on individual companies.
Moat and Competitive Advantages
Competitive Edge
MEDX's competitive edge lies in its active management and concentrated approach, seeking to exploit inefficiencies and undiscovered growth opportunities within the medical sector. The managers aim to identify companies with disruptive technologies or strong competitive moats in their specific niches. This focused strategy allows for potentially higher alpha generation compared to broad-market index funds, by hand-picking promising, under-the-radar medical innovators.
Risk Analysis
Volatility
The historical volatility of MEDX is likely to be higher than broad-market healthcare ETFs due to its concentrated portfolio and focus on smaller-cap, growth-oriented companies. These companies can experience more significant price swings.
Market Risk
Specific market risks include regulatory changes affecting drug approvals or healthcare services, patent cliff events, competition from generic alternatives, and shifts in investor sentiment towards growth stocks. The concentrated nature of the portfolio means that the poor performance of a few key holdings could significantly impact overall returns.
Investor Profile
Ideal Investor Profile
The ideal investor for MEDX is an individual seeking long-term capital appreciation, comfortable with higher risk and volatility, and who believes in the potential of actively managed strategies in the healthcare sector. They should have a strong understanding of the medical industry and the specific investment thesis of the fund.
Market Risk
MEDX is generally best suited for long-term investors who are looking for concentrated exposure to high-growth medical companies and are willing to accept the risks associated with active management and a less diversified portfolio. It is not typically recommended for short-term traders or those seeking broad, passive market exposure.
Summary
The Horizon Kinetics Medical ETF (MEDX) is an actively managed fund focusing on high-growth medical companies. It seeks long-term capital appreciation through a concentrated portfolio of innovative healthcare stocks. While offering potential for alpha generation, it carries higher risk and volatility compared to passive healthcare ETFs due to its active management and concentrated holdings. Its expense ratio is also higher than index-tracking alternatives. MEDX is best suited for risk-tolerant, long-term investors with a conviction in the fund's active management strategy within the dynamic healthcare sector.
Similar ETFs
Sources and Disclaimers
Data Sources:
- Horizon Kinetics Official Website (Hypothetical - actual data requires live access)
- Financial Data Providers (e.g., Morningstar, ETF Database, Bloomberg - Hypothetical)
- SEC Filings (Hypothetical)
Disclaimers:
This information is for illustrative purposes only and should not be considered investment advice. ETF performance can vary, and past performance is not indicative of future results. Investors should conduct their own due diligence and consult with a financial advisor before making investment decisions. Market share data and competitor information are estimates and subject to change.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About Horizon Kinetics Medical ETF
Exchange NASDAQ | Headquaters - | ||
IPO Launch date - | CEO - | ||
Sector - | Industry - | Full time employees - | Website |
Full time employees - | Website | ||
The fund is an actively-managed exchange-traded fund ("ETF") that pursues its investment objective by investing, under normal circumstances, at least 80% of its net assets plus any borrowings for investment purposes in common stocks, convertible securities, warrants and other equity securities having the characteristics of common stocks of U.S. and foreign companies engaged in medical research, pharmaceutical and medical technology industries and related technology industries. The fund is non-diversified.

Note: This website is maintained by Upturn Corporation, which is an investment adviser registered with the U.S. Securities and Exchange Commission. Such registration does not imply a certain level of skill or training. Investing in securities has risks. Past performance is no guarantee of future returns. No assurance is provided as to any particular investment return, and you may lose money using our services. You are strongly advised to consult appropriate counsel before making any investments in companies you learn about through our services. You should obtain appropriate legal, tax, investment, accounting, and other advice that takes into account your investment portfolio and overall financial situation. You are solely responsible for conducting due diligence on a potential investment. We do not affect trades for you. You will select your own broker through which to transact. Investments are not FDIC insured, they are not guaranteed, and they may lose value. Please see the Privacy Policy, Terms of Use, and Disclosure for more information.
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