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OZEM
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Roundhill GLP-1 & Weight Loss ETF (OZEM)

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$24.58
Last Close (24-hour delay)
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PASS
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Upturn Advisory Summary

08/14/2025: OZEM (1-star) is currently NOT-A-BUY. Pass it for now.

Upturn Star Rating

rating

Not Recommended Performance

These Stocks/ETFs, based on Upturn Advisory, consistently fall short of market performance, signaling caution before investing.

Analysis of Past Performance

Type ETF
Historic Profit -7.04%
Avg. Invested days 28
Today’s Advisory PASS
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Upturn Advisory Performance Upturn Advisory Performance 1.0
ETF Returns Performance Upturn Returns Performance 1.0
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Upturn Profits based on simulationUpturn Profits based on simulation Last Close 08/14/2025

Key Highlights

Volume (30-day avg) -
Beta -
52 Weeks Range 20.01 - 29.15
Updated Date 06/30/2025
52 Weeks Range 20.01 - 29.15
Updated Date 06/30/2025

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Roundhill GLP-1 & Weight Loss ETF

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ETF Overview

overview logo Overview

The Roundhill GLP-1 & Weight Loss ETF (OZEM) seeks to provide investment results that correspond to the Roundhill GLP-1 & Weight Loss Index. The fund invests in companies that are engaged in the development, production, or sale of GLP-1 receptor agonists and other weight loss drugs.

reliability logo Reputation and Reliability

Roundhill Investments is known for its thematic ETFs focusing on emerging and disruptive technologies and trends. They have a moderate track record, with some successful niche funds.

reliability logo Management Expertise

Roundhill's management team has experience in ETF creation and thematic investing, leveraging market trends to build targeted investment products.

Investment Objective

overview logo Goal

The ETF aims to provide investors with exposure to companies involved in the rapidly growing GLP-1 and weight loss drug market.

Investment Approach and Strategy

Strategy: The ETF tracks the Roundhill GLP-1 & Weight Loss Index, a rules-based index designed to capture the performance of companies focused on weight loss treatments.

Composition The ETF primarily holds stocks of pharmaceutical companies, biotechnology firms, and other healthcare companies involved in the development, manufacturing, and distribution of GLP-1 receptor agonists and other weight loss related products and services.

Market Position

Market Share: OZEM is one of the first ETFs focusing specifically on GLP-1 and weight loss, giving it a relatively high market share in this nascent niche.

Total Net Assets (AUM): 116900000

Competitors

overview logo Key Competitors

  • DRUG
  • IHE
  • PJP
  • XHE

Competitive Landscape

The ETF industry for the GLP-1 and weight loss market is still in its early stages. OZEM, as one of the first entrants, benefits from a first-mover advantage. Competitors are more broadly diversified healthcare ETFs which don't focus solely on weight loss, providing less concentrated exposure. OZEM's specific focus is an advantage for investors seeking targeted exposure, but it can also be a disadvantage if the weight loss sector underperforms the broader healthcare market.

Financial Performance

Historical Performance: Historical performance data is relatively limited given the ETF's recent inception. Performance should be tracked against the Roundhill GLP-1 & Weight Loss Index.

Benchmark Comparison: The ETF's performance should be compared to its underlying index, the Roundhill GLP-1 & Weight Loss Index, to assess tracking error.

Expense Ratio: 0.59

Liquidity

Average Trading Volume

The average trading volume is moderate, which might impact the ease of buying and selling large blocks of shares.

Bid-Ask Spread

The bid-ask spread is generally reasonable, reflecting moderate liquidity, but investors should be mindful of this cost, especially for larger trades.

Market Dynamics

Market Environment Factors

Growth in the GLP-1 drug market is being driven by increasing awareness of obesity and diabetes, advancements in pharmaceutical research, and increased regulatory approvals. Changing demographics, such as aging populations and rising obesity rates, also contribute to growth.

Growth Trajectory

The ETF's growth trajectory is closely tied to the success and adoption of GLP-1 drugs. Potential changes in strategy could include expanding the index to include adjacent markets or modifying the weighting methodology.

Moat and Competitive Advantages

Competitive Edge

OZEM's primary advantage is its highly specialized focus on the GLP-1 and weight loss drug market, providing targeted exposure that broader healthcare ETFs cannot replicate. As a first mover in the thematic ETF space, it benefits from greater visibility and potential for asset growth. Furthermore, the association with Roundhill investments and their specialized ETF structure provides a competitive edge. The ETF may attract investors seeking a concentrated bet on the future of weight loss treatments.

Risk Analysis

Volatility

The ETF's volatility is expected to be relatively high, reflecting the growth-oriented nature of the companies it holds.

Market Risk

Specific risks include regulatory hurdles for new drugs, competition among pharmaceutical companies, and potential side effects or safety concerns related to GLP-1 drugs. Market sentiment towards the weight loss sector and overall healthcare industry can also impact performance.

Investor Profile

Ideal Investor Profile

The ideal investor is someone who is interested in the biotechnology and pharmaceutical industries, has a high-risk tolerance, and believes in the growth potential of the weight loss market.

Market Risk

This ETF is best suited for long-term investors who are comfortable with the potential volatility and are looking for targeted exposure to a specific growth area within the healthcare sector.

Summary

The Roundhill GLP-1 & Weight Loss ETF (OZEM) offers targeted exposure to companies involved in the burgeoning GLP-1 and weight loss drug market. As a thematic ETF, OZEM presents a focused investment opportunity with significant growth potential, although it's subject to higher volatility. Ideal investors are those with a high-risk tolerance and a long-term investment horizon. The success of OZEM is dependent on the continued growth and adoption of GLP-1 therapies, but also presents certain risk related to regulatory and political factors.

Peer Comparison

Sources and Disclaimers

Data Sources:

  • Roundhill Investments website
  • ETF.com
  • Bloomberg

Disclaimers:

The data provided is for informational purposes only and should not be considered financial advice. Past performance is not indicative of future results. Investors should consult with a qualified financial advisor before making any investment decisions.

Upturn AI SummarizationUpturn AI Summarization AI Summarization is directionally correct and might not be accurate.

Upturn AI SummarizationUpturn AI Summarization Summarized information shown could be a few years old and not current.

Upturn AI SummarizationUpturn AI Summarization Fundamental Rating based on AI could be based on old data.

Upturn AI SummarizationUpturn AI Summarization AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.

About Roundhill GLP-1 & Weight Loss ETF

Exchange NASDAQ
Headquaters -
IPO Launch date -
CEO -
Sector -
Industry -
Full time employees -
Website
Full time employees -
Website

The fund's manager will invest at least 80% of its net assets (plus any borrowings for investment purposes) in the equity securities of GLP-1 & Weight Loss Companies or any derivative instruments (such as swap agreements or forward contracts) that utilize one or more GLP-1 & Weight Loss Companies as the reference asset. The fund is non-diversified.