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OZEM
Upturn stock rating

Roundhill GLP-1 & Weight Loss ETF (OZEM)

Upturn stock rating
$27.56
Last Close (24-hour delay)
Profit since last BUY4.95%
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Consider higher Upturn Star rating
BUY since 36 days
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Upturn Advisory Summary

10/24/2025: OZEM (1-star) has a low Upturn Star Rating. Not recommended to BUY.

Upturn Star Rating

rating

Not Recommended Performance

These Stocks/ETFs, based on Upturn Advisory, consistently fall short of market performance, signaling caution before investing.

Analysis of Past Performance

Type ETF
Historic Profit -2.44%
Avg. Invested days 30
Today’s Advisory Consider higher Upturn Star rating
Upturn Star Rating upturn star rating icon
Upturn Advisory Performance Upturn Advisory Performance 2.0
ETF Returns Performance Upturn Returns Performance 1.0
Upturn Profits based on simulation Profits based on simulation
Upturn Profits based on simulation Last Close 10/24/2025

Key Highlights

Volume (30-day avg) -
Beta -
52 Weeks Range 20.01 - 29.15
Updated Date 06/30/2025
52 Weeks Range 20.01 - 29.15
Updated Date 06/30/2025

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Roundhill GLP-1 & Weight Loss ETF

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ETF Overview

overview logo Overview

The Roundhill GLP-1 & Weight Loss ETF (OZEM) seeks to provide investment results that closely correspond, before fees and expenses, to the performance of the Solactive Global OSEM Weight Loss Index. The fund focuses on companies expected to derive significant revenue from GLP-1 drugs and weight loss products.

reliability logo Reputation and Reliability

Roundhill Investments is known for thematic ETFs focusing on innovative sectors. They are generally considered a reliable issuer, although they are a smaller player compared to established giants like BlackRock or Vanguard.

reliability logo Management Expertise

Roundhill's management team has experience in the ETF industry, focusing on identifying and developing thematic investment strategies.

Investment Objective

overview logo Goal

To track the performance of the Solactive Global OSEM Weight Loss Index, which focuses on companies involved in the GLP-1 and weight loss market.

Investment Approach and Strategy

Strategy: The ETF aims to replicate the performance of the Solactive Global OSEM Weight Loss Index.

Composition The ETF primarily holds stocks of companies involved in the development, production, and distribution of GLP-1 drugs and weight loss products.

Market Position

Market Share: OZEM is a relatively new entrant in the weight loss ETF market, and its market share is growing, but is still much smaller than broader healthcare ETFs.

Total Net Assets (AUM): 34000000.0

Competitors

overview logo Key Competitors

  • IShares US Pharmaceuticals ETF (IHE)
  • SPDR S&P Biotech ETF (XBI)
  • VanEck Biotech ETF (BBH)

Competitive Landscape

The competitive landscape includes broader healthcare and biotech ETFs as well as any potential future thematic weight loss ETFs. OZEM has the advantage of a highly focused approach on GLP-1 and weight loss but faces the disadvantage of being a niche ETF with lower AUM compared to diversified and established players.

Financial Performance

Historical Performance: Historical performance data is still limited due to the ETF's recent inception. Performance will be highly correlated to the performance of GLP-1 related stocks.

Benchmark Comparison: The ETF's performance can be compared to the Solactive Global OSEM Weight Loss Index, although the performance history is short.

Expense Ratio: 0.59

Liquidity

Average Trading Volume

The ETF's average trading volume is moderate, indicating reasonable liquidity for most investors.

Bid-Ask Spread

The bid-ask spread is generally moderate, but may widen during periods of market volatility or low trading volume.

Market Dynamics

Market Environment Factors

The ETF is affected by factors influencing the pharmaceutical and biotechnology industries, including regulatory approvals, clinical trial results, and competition in the GLP-1 market.

Growth Trajectory

The ETF's growth trajectory depends on the continued growth and adoption of GLP-1 drugs for weight loss and diabetes management. It may be subject to changes in index methodology or holdings based on market developments.

Moat and Competitive Advantages

Competitive Edge

OZEM offers a targeted approach to investing in the growing GLP-1 and weight loss market, potentially offering higher returns than broader healthcare ETFs. The ETF's focused strategy allows investors to specifically target this niche market. Roundhill's expertise in thematic ETFs provides an advantage. It is designed to benefit from the growing popularity of GLP-1 drugs for weight loss and diabetes management.

Risk Analysis

Volatility

The ETF's volatility can be expected to be high due to its concentration in a specific sector and the potential for fluctuations in the performance of GLP-1 related stocks.

Market Risk

The ETF is subject to market risk, including the risk of changes in investor sentiment, regulatory changes, and competition in the pharmaceutical and biotechnology industries.

Investor Profile

Ideal Investor Profile

The ideal investor is someone who is bullish on the long-term growth prospects of the GLP-1 and weight loss market and is willing to accept higher risk for potentially higher returns.

Market Risk

The ETF is suitable for long-term investors who are looking for targeted exposure to the GLP-1 and weight loss sector.

Summary

The Roundhill GLP-1 & Weight Loss ETF (OZEM) provides targeted exposure to companies involved in the GLP-1 and weight loss market. While a niche ETF, its highly focused strategy sets it apart from broader healthcare ETFs. OZEM carries higher risk and volatility due to its concentration in a specific sector. Investors should carefully consider their risk tolerance and investment objectives before investing.

Peer Comparison

Sources and Disclaimers

Data Sources:

  • Roundhill Investments website
  • Solactive website
  • ETF.com
  • Morningstar

Disclaimers:

The data provided is for informational purposes only and should not be considered investment advice. Investors should consult with a qualified financial advisor before making any investment decisions. Market share data is based on the last available data and may not reflect current market conditions.

Upturn AI Summarization AI Summarization is directionally correct and might not be accurate.

Upturn AI Summarization Summarized information shown could be a few years old and not current.

Upturn AI Summarization Fundamental Rating based on AI could be based on old data.

Upturn AI Summarization AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.

About Roundhill GLP-1 & Weight Loss ETF

Exchange NASDAQ
Headquaters -
IPO Launch date -
CEO -
Sector -
Industry -
Full time employees -
Website
Full time employees -
Website

The fund's manager will invest at least 80% of its net assets (plus any borrowings for investment purposes) in the equity securities of GLP-1 & Weight Loss Companies or any derivative instruments (such as swap agreements or forward contracts) that utilize one or more GLP-1 & Weight Loss Companies as the reference asset. The fund is non-diversified.