Upturn unsubscribed user
$1.14/ day, billed weekly
Cancel anytime
(Ad-Free, Unlimited access)​
NO CREDIT CARD REQUIRED
ACAD logo ACAD
Upturn stock ratingUpturn stock rating
ACAD logo

ACADIA Pharmaceuticals Inc (ACAD)

Upturn stock ratingUpturn stock rating
$24.67
Last Close (24-hour delay)
Profit since last BUY37.59%
upturn advisory
SELL
SELL since 2 days
  • BUY Advisory
  • SELL Advisory (Profit)​
  • SELL Advisory (Loss)​
  • Profit
  • Loss
  • Pass (Skip investing)
Upturn Stock infoUpturn Stock info Stock price based on last close
*as per simulation
(see disclosures)
Time period over
  • ALL
  • YEAR
  • MONTH
  • WEEK

Upturn Advisory Summary

09/15/2025: ACAD (3-star) is a SELL. SELL since 2 days. Simulated Profits (37.59%). Updated daily EoD!

Upturn Star Rating

rating

Moderate Performance

These Stocks/ETFs, based on Upturn Advisory, typically align with the market average, offering steady but unremarkable returns.

Number of Analysts

rating

20 Analysts rated it

Well-followed company, solid analyst reports, reliable data for confident investing.

1 Year Target Price $30.32

1 Year Target Price $30.32

Analysts Price Target For last 52 week
$30.32 Target price
52w Low $13.4
Current$24.67
52w High $26.65

Analysis of Past Performance

Type Stock
Historic Profit 42.56%
Avg. Invested days 54
Today’s Advisory SELL
Upturn Star Rating Upturn stock ratingUpturn stock rating
Upturn Advisory Performance Upturn Advisory Performance 3.0
Stock Returns Performance Upturn Returns Performance 3.0
Upturn Profits based on simulationUpturn Profits based on simulation Profits based on simulation
Upturn Profits based on simulationUpturn Profits based on simulation Last Close 09/15/2025

Key Highlights

Company Size Mid-Cap Stock
Market Capitalization 3.98B USD
Price to earnings Ratio 17.75
1Y Target Price 30.32
Price to earnings Ratio 17.75
1Y Target Price 30.32
Volume (30-day avg) 20
Beta 0.75
52 Weeks Range 13.40 - 26.65
Updated Date 09/14/2025
52 Weeks Range 13.40 - 26.65
Updated Date 09/14/2025
Dividends yield (FY) -
Basic EPS (TTM) 1.33

Analyzing Revenue: Products, Geography and Growth

Revenue by Products

Earnings Date

Report Date -
When -
Estimate -
Actual -

Profitability

Profit Margin 21.8%
Operating Margin (TTM) 12.24%

Management Effectiveness

Return on Assets (TTM) 5.28%
Return on Equity (TTM) 33.18%

Valuation

Trailing PE 17.75
Forward PE 22.94
Enterprise Value 3277593514
Price to Sales(TTM) 3.91
Enterprise Value 3277593514
Price to Sales(TTM) 3.91
Enterprise Value to Revenue 3.22
Enterprise Value to EBITDA 31.53
Shares Outstanding 168712000
Shares Floating 115869866
Shares Outstanding 168712000
Shares Floating 115869866
Percent Insiders 0.55
Percent Institutions 103.22

ai summary icon Upturn AI SWOT

ACADIA Pharmaceuticals Inc

stock logo

Company Overview

overview logo History and Background

ACADIA Pharmaceuticals Inc. was founded in 1993. Initially focused on discovering drugs for neurodegenerative disorders, it later shifted its focus to neuropsychiatric disorders. A significant milestone was the FDA approval of Nuplazid in 2016, marking its transition to a commercial-stage company.

business area logo Core Business Areas

  • Neurology: Focuses on developing and commercializing therapies for neurological disorders, including Parkinson's disease psychosis.
  • Psychiatry: Focuses on developing and commercializing therapies for psychiatric disorders, including major depressive disorder.

leadership logo Leadership and Structure

The leadership team includes the CEO, Chief Medical Officer, and heads of various departments like research and development, commercial operations, and finance. The organizational structure is hierarchical, with departments reporting to senior management.

Top Products and Market Share

overview logo Key Offerings

  • Nuplazid (pimavanserin): Nuplazid is used to treat hallucinations and delusions associated with Parkinson's disease psychosis. ACADIA holds a dominant market share in the PDP treatment space. Competitors include generic antipsychotics, though Nuplazid is the only FDA-approved drug for PDP. 2023 Nuplazid net sales: $597.8 million.
  • Daybue (trofinetide): Daybue is used to treat Rett syndrome in adults and children 2 years of age and older. Competitors include symptomatic therapies. Daybue was approved by the FDA in March 2023.

Market Dynamics

industry overview logo Industry Overview

The pharmaceutical industry is highly competitive and regulated. It involves research, development, manufacturing, and marketing of drugs. Demand is driven by aging populations and increasing prevalence of chronic diseases.

Positioning

ACADIA is positioned as a specialty pharmaceutical company focusing on innovative therapies for central nervous system disorders. Its competitive advantage lies in its focus on underserved markets and its proprietary drug development platform.

Total Addressable Market (TAM)

The TAM for neurological and psychiatric disorders is significant and growing. ACADIA is well-positioned to capture a portion of this TAM through its targeted therapies. Estimates put the PDP market at several billion dollars, with Rett syndrome having a smaller but still substantial TAM.

Upturn SWOT Analysis

Strengths

  • FDA-approved products
  • Proprietary drug development platform
  • Strong market position in PDP
  • Experienced management team

Weaknesses

  • Reliance on a limited number of products
  • Dependence on patent protection
  • High research and development costs
  • Regulatory risks

Opportunities

  • Expanding product pipeline
  • Geographic expansion
  • Acquisitions and partnerships
  • New indications for existing products

Threats

  • Competition from other pharmaceutical companies
  • Generic entry of Nuplazid
  • Unfavorable regulatory changes
  • Product liability litigation

Competitors and Market Share

competitor logo Key Competitors

  • TEVA
  • VTRS
  • ITCI

Competitive Landscape

ACADIA's advantage lies in its FDA-approved therapies for underserved markets. Disadvantages include reliance on a limited product portfolio and competition from generic drugs.

Growth Trajectory and Initiatives

Historical Growth: ACADIA has experienced significant revenue growth following the approval and commercialization of Nuplazid. Daybue represents additional growth catalyst.

Future Projections: Analysts project continued revenue growth driven by increased Nuplazid sales and Daybue market penetration. Profitability is expected to improve as revenue scales.

Recent Initiatives: Recent initiatives include expanding the label for Nuplazid, the commercial launch of Daybue, and advancing pipeline programs.

Summary

ACADIA Pharmaceuticals is a growing specialty pharmaceutical company with a focus on central nervous system disorders. The commercialization of Nuplazid and Daybue drives growth, but high R&D costs contribute to ongoing net losses. The company must manage regulatory risks, competition, and potential generic entry of Nuplazid while continuing to expand its pipeline.

Peer Comparison

Sources and Disclaimers

Data Sources:

  • ACADIA Pharmaceuticals Inc. Investor Relations
  • SEC Filings
  • Analyst Reports
  • Company Press Releases

Disclaimers:

The information provided is for informational purposes only and should not be considered financial advice. Market share data are estimates and may vary. Investment decisions should be based on individual research and consultation with a financial advisor.

Upturn AI SummarizationUpturn AI Summarization AI Summarization is directionally correct and might not be accurate.

Upturn AI SummarizationUpturn AI Summarization Summarized information shown could be a few years old and not current.

Upturn AI SummarizationUpturn AI Summarization Fundamental Rating based on AI could be based on old data.

Upturn AI SummarizationUpturn AI Summarization AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.

About ACADIA Pharmaceuticals Inc

Exchange NASDAQ
Headquaters San Diego, CA, United States
IPO Launch date 2004-05-27
CEO & Director Ms. Catherine E. Owen Adams
Sector Healthcare
Industry Biotechnology
Full time employees 653
Full time employees 653

ACADIA Pharmaceuticals Inc., a biopharmaceutical company, focuses on the development and commercialization of medicines for central nervous system (CNS) disorders and rare diseases in the United States. The company offers NUPLAZID (pimavanserin) for the treatment of hallucinations and delusions associated with Parkinson's disease psychosis; and DAYBUE, a novel synthetic analog of the amino-terminal tripeptide of insulin-like growth factor 1 for treatment of Rett Syndrome. It also develops Pimavanserin which completed Phase III clinical trial to treat the negative symptoms of schizophrenia; ACP-101, which completed phase III clinical trial for the treatment of hyperphagia in Prader-Willi syndrome; ACP-204 that completed phase II clinical trial for the treatment of Alzheimer's disease psychosis and Lewy Body Dementia with psychosis; ACP-711, which is in phase I clinical trial for the treatment of essential tremor; ACP-211 that is in phase I clinical trial for the treatment of treatment-resistant depression; ACP-2591 that is in Phase I development for Rett syndrome and Fragile X syndrome; and ACP-271, a GPR88 agonist used in evaluation of neurology and is in the IND-enabling stage. The company has a license agreement with Neuren Pharmaceuticals Limited to trofinetide for Rett syndrome and other indications; and a license and collaboration agreement with Stoke Therapeutics, Inc. to discover, develop and commercialize novel RNA-based medicines for the potential treatment of severe and rare genetic neurodevelopmental diseases of the CNS. The company was formerly known as Receptor Technologies, Inc. and changed its name ACADIA Pharmaceuticals Inc. in 1997. ACADIA Pharmaceuticals Inc. was incorporated in 1993 and is headquartered in San Diego, California.