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Adicet Bio Inc (ACET)

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Upturn Advisory Summary
10/27/2025: ACET (1-star) has a low Upturn Star Rating. Not recommended to BUY.
1 Year Target Price $6.17
1 Year Target Price $6.17
| 6 | Strong Buy |
| 0 | Buy |
| 1 | Hold |
| 0 | Sell |
| 0 | Strong Sell |
Analysis of Past Performance
Type Stock | Historic Profit -32.79% | Avg. Invested days 31 | Today’s Advisory Consider higher Upturn Star rating |
Upturn Star Rating ![]() | Upturn Advisory Performance | Stock Returns Performance |
Key Highlights
Company Size Small-Cap Stock | Market Capitalization 136.40M USD | Price to earnings Ratio - | 1Y Target Price 6.17 |
Price to earnings Ratio - | 1Y Target Price 6.17 | ||
Volume (30-day avg) 7 | Beta 1.63 | 52 Weeks Range 0.45 - 1.45 | Updated Date 10/26/2025 |
52 Weeks Range 0.45 - 1.45 | Updated Date 10/26/2025 | ||
Dividends yield (FY) - | Basic EPS (TTM) -1.3 |
Analyzing Revenue: Products, Geography and Growth
Revenue by Products
Product revenue - Year on Year
Revenue by Geography
Geography revenue - Year on Year
Earnings Date
Report Date - | When - | Estimate - | Actual - |
Profitability
Profit Margin - | Operating Margin (TTM) - |
Management Effectiveness
Return on Assets (TTM) -36.52% | Return on Equity (TTM) -64.39% |
Valuation
Trailing PE - | Forward PE - | Enterprise Value -40679197 | Price to Sales(TTM) 9.72 |
Enterprise Value -40679197 | Price to Sales(TTM) 9.72 | ||
Enterprise Value to Revenue 2.14 | Enterprise Value to EBITDA -1.21 | Shares Outstanding 153254779 | Shares Floating 76293661 |
Shares Outstanding 153254779 | Shares Floating 76293661 | ||
Percent Insiders 2.74 | Percent Institutions 66.92 |
Upturn AI SWOT
Adicet Bio Inc

Company Overview
History and Background
Adicet Bio, Inc. is a biotechnology company focused on developing allogeneic gamma delta T-cell therapies for cancer. Founded in 2014, the company has progressed through preclinical and clinical stages, focusing on developing novel immunotherapies to address unmet needs in oncology.
Core Business Areas
- Gamma Delta T-Cell Therapies: Adicet Bio focuses on developing allogeneic gamma delta T-cell therapies for cancer. They engineer and manufacture these cells to enhance their anti-tumor activity.
- Pipeline Development: The company develops and advances its pipeline of therapeutic candidates from discovery to clinical trials.
Leadership and Structure
Chen Schor serves as the President and Chief Executive Officer. The company has a structured leadership team responsible for research and development, clinical operations, and corporate strategy.
Top Products and Market Share
Key Offerings
- ADI-001: ADI-001 is Adicet Bio's lead product candidate, an allogeneic gamma delta T-cell therapy targeting CD20-positive B-cell lymphomas. Clinical trials are ongoing. Competitors include autologous CAR-T therapies such as Yescarta and Kymriah. No current Market Share data available.
- ADI-270: ADI-270 is an allogeneic gamma delta T-cell therapy engineered to target solid tumors expressing EGFR. The product is in preclinical development. Competitors include companies developing other EGFR-targeted therapies. No current Market Share data available.
Market Dynamics
Industry Overview
The oncology therapeutics market is a large and rapidly growing market. Immunotherapy, including cell therapies, is a significant area of focus.
Positioning
Adicet Bio is positioned within the allogeneic cell therapy space, aiming to provide off-the-shelf therapies. Competitive advantages include its gamma delta T-cell platform and engineering capabilities.
Total Addressable Market (TAM)
The TAM for cell therapies in oncology is estimated to be in the tens of billions of dollars. Adicet Bio is positioned to capture a portion of this market by addressing specific cancer types with its therapies. The TAM is expected to grow as the market matures.
Upturn SWOT Analysis
Strengths
- Novel gamma delta T-cell platform
- Allogeneic approach (off-the-shelf)
- Strong preclinical data
- Experienced management team
Weaknesses
- Early stage clinical development
- High R&D costs
- Limited clinical data to date
- Dependence on successful clinical trials
Opportunities
- Partnerships with larger pharmaceutical companies
- Expansion of pipeline to other cancer types
- Positive clinical trial results
- Advancements in cell engineering technologies
Threats
- Competition from established cell therapy companies
- Clinical trial failures
- Regulatory hurdles
- Manufacturing challenges
Competitors and Market Share
Key Competitors
- GILD
- BMY
- TMO
- NVS
Competitive Landscape
Adicet Bio competes with both large pharmaceutical companies and smaller biotech companies in the cell therapy space. Its allogeneic approach offers advantages over autologous therapies but faces challenges in terms of efficacy and safety compared to autologous competitors. Gilead (kite) and Bristol Myers Squibb are 2 of the leading cell therapy companies in the USA.
Growth Trajectory and Initiatives
Historical Growth: Historical growth would be characterized by pipeline development, partnerships, and financing activities.
Future Projections: Future growth is dependent on clinical trial success, regulatory approvals, and market adoption of its therapies. Analyst estimates would be needed to provide concrete projections.
Recent Initiatives: Recent initiatives include advancing clinical trials for ADI-001, progressing preclinical programs, and exploring partnerships.
Summary
Adicet Bio is a biotechnology company focused on developing allogeneic gamma delta T-cell therapies for cancer. Their novel approach offers potential advantages over traditional cell therapies, however, they are in early-stage development. Success depends on positive clinical trial outcomes and regulatory approvals. They need to watch out for manufacturing challenges and competition from established players.
Peer Comparison
Sources and Disclaimers
Data Sources:
- Company Website
- SEC Filings
- Analyst Reports (Estimates)
Disclaimers:
The information provided is for informational purposes only and should not be considered financial advice. Market share is estimated and subject to change. Investment decisions should be made based on thorough research and consultation with a financial advisor.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About Adicet Bio Inc
Exchange NASDAQ | Headquaters Boston, MA, United States | ||
IPO Launch date 2018-01-26 | CEO, President & Director Mr. Chen Schor BA, CPA, M.B.A. | ||
Sector Healthcare | Industry Biotechnology | Full time employees 152 | Website https://www.adicetbio.com |
Full time employees 152 | Website https://www.adicetbio.com | ||
Adicet Bio, Inc., a clinical stage biotechnology company, discovers and develops allogeneic gamma delta T cell therapies for autoimmune diseases and cancer in the United States. It offers gamma delta T cells engineered with chimeric antigen receptors (CARs) to facilitate durable activity in patients. The company's lead product candidate is ADI-001, an allogeneic gamma delta T cell therapy expressing a CAR targeting CD20, which is in Phase I clinical trial for the potential treatment of autoimmune diseases and relapsed/refractory B-cell non-hodgkin's lymphoma. It also develops ADI-270, an armored gamma delta CAR T cell product candidate to treat multiple CD70+ solid tumor and hematological malignancies indications, with renal cell carcinoma. The company was founded in 2014 and is based in Boston, Massachusetts.

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