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Upturn AI Summary - About
Acrivon Therapeutics, Inc. Common Stock(ACRV)
Advisory History & Simulated Performance *
*as per simulation (see disclosures)- ALL
- 1Y
- 1M
- 1W
- BUY Advisory
- SELL Advisory (Profit)
- SELL Advisory (Loss)
- Profit
- Loss
- PASS (Skip)
Stock price based on last close Advisory Performance History (Simulated)
Upturn Advisory & Investor View for ACRV
11/05/2026: ACRV (1-star) is currently NOT-A-BUY. Pass it for now.
Acrivon Therapeutics is a clinical-stage biotechnology company focused on precision oncology, utilizing its proprietary AP3 proteomics platform to identify patients most likely to respond to its drug candidates. The company’s core strength lies in its novel diagnostic-led approach to drug development, which seeks to improve clinical success rates in solid tumors. Its primary investment story hinges on the success of its lead candidate, ACR-368, and the validation of its platform. Key risks include the pre-revenue nature of the business, high cash burn, and intense competition from large-cap pharmaceutical firms. The stock is best suited for high-risk, growth-oriented investors monitoring clinical trial readouts.
How to Read the Upturn Advisory
The Upturn Star Rating and the current BUY, SELL, or PASS advisory are generated by Upturn’s AI advisory engine based on proprietary signal analysis, price behavior, advisory history, and historical signal performance.
Company fundamentals, valuation, risks, and news provide supporting context about the business.
Investor Fit
| Investor style | Fit | Why |
|---|---|---|
| Growth investor | Mixed fit | The company offers high growth potential if its clinical trials succeed, but it is currently highly speculative. |
| Momentum investor | Strong fit while signal remains positive | Biotech stocks often experience strong momentum around positive clinical data readouts. |
| Value investor | Weak fit | The company lacks current earnings or assets to justify a value-based investment thesis. |
| Dividend investor | Weak fit | As a pre-revenue biotechnology company, it does not pay dividends. |
| Low-risk investor | Weak fit | The company carries extreme binary risk associated with clinical trial outcomes. |
Risk Profile
| Risk factor | Level | Why it matters |
|---|---|---|
| Price volatility | High | Clinical-stage biotech stocks are subject to sharp price swings based on trial results and market sentiment. |
| Valuation risk | High | Valuations are highly subjective and dependent on future, uncertain clinical successes. |
| Competition risk (DDR/Oncology) | Medium / high | Large pharmaceutical companies may develop superior therapies that render Acrivon's pipeline obsolete. |
| Business quality | Medium | The reliance on a single unproven diagnostic platform for pipeline selection presents a specific execution concentration risk. |
| Dividend income | Low / none | Investors should expect zero income from this equity. |
| Execution risk | High | The company must successfully navigate complex clinical and regulatory paths to reach commercialization. |
Price Behavior
Rolling Over
The price momentum is slowing down and beginning to turn downward.
Choppy
The stock has experienced frequent reversals and pronounced short-term price swings.
Analysis of Past Performance
Type Stock | Historic Profit -57.24% | Avg. Invested days 26 | Today’s Advisory PASS |
Upturn Advisory Rating  | Upturn Advisory Performance  2.0 | Stock Returns Performance  1.0 |
| Profits based on simulation | Last Close 11/05/2026 |
Upturn Scorecard
Upturn Star Rating 
Company Fundamentals
Financial Health Rating
Growth Momentum Score
Ownership
Top 5 Institutional Investors
Unit Economics (Per $1K Revenue)
Economic Dimensions
Quantitative Style Profile
Style Classification
Quality Focused
Key Highlights
Company Size Small-Cap Stock | Market Capitalization 74.56M USD | Price to earnings Ratio - | 1Y Target Price 11.5 |
Price to earnings Ratio - | 1Y Target Price 11.5 | ||
Volume (30-day avg) 207.1K shares | Beta 1.98 | 52 Weeks Range 1.27 - 3.56 | Updated Date 11/04/2026 |
52 Weeks Range 1.27 - 3.56 | Updated Date 11/04/2026 | ||
Dividends yield (FY) - | Basic EPS (TTM) -1.88 |
How Company Makes Money
| Business area | What it includes | Retail investor read |
|---|---|---|
| Clinical Development | Advancing drug candidates like ACR-368 through clinical trials for future potential FDA approval. | The company currently spends money to test drugs and is not yet selling products. |
| AP3 Platform Research | Using proprietary proteomics to identify patient populations for drug efficacy. | This is their core technology that aims to make their drugs more likely to work. |
Valuation
Trailing PE - | Forward PE - | Enterprise Value -17.14M | Price to Sales(TTM) - |
Enterprise Value -17.14M | Price to Sales(TTM) - | ||
Enterprise Value to Revenue - | Enterprise Value to EBITDA -0.43 | Shares Outstanding 42.85M | Shares Floating 25.83M |
Shares Outstanding 42.85M | Shares Floating 25.83M | ||
Percent Insiders 15.4 | Percent Institutions 50.34 |
Financial Metrics
🧭 Investment Snapshot
Total Revenue (Scale)
Total money earned from selling products or services before any costs. It is needed to understand the scale of the business and its ability to generate income.
Net Income (Profit)
Final profit after all expenses, interest, and taxes are deducted. It is needed to determine the overall profitability available to shareholders.
Free Cash Flow (Cash Strength)
Cash remaining after operating activities and capital expenditures, showing cash available for growth. It is needed to evaluate the company’s ability to invest, pay dividends, or reduce debt.
📈 Growth & Strength
Operating Income (Core Profit)
Profit from core operations after deducting all operating expenses. It is needed to measure how efficiently the company runs its primary business activities.
EBITDA (Cash Earnings)
Earnings before interest, taxes, depreciation, and amortization, indicating operating cash potential. It is needed to compare operating performance across companies without accounting or financing differences.
Gross Profit (Unit Profitability)
Revenue minus cost of revenue, showing profit after direct production costs. It is needed to evaluate core business profitability before overhead expenses.
🛡️ Financial Safety
Cash (Liquidity Buffer)
Total cash and cash equivalents on hand. It is needed to evaluate immediate liquidity and financial flexibility.
Total Debt (Leverage Risk)
Total debt including both short-term and long-term components. It is needed to assess the company’s leverage and financial risk.
Net Working Capital (Short-Term Health)
Current assets minus current liabilities, indicating short-term liquidity strength. It is needed to assess whether the company can meet its short-term obligations.
🧱 Balance Sheet Strength
Stockholder Equity (Net Worth)
Total equity value held by shareholders. It is needed to understand the net worth of the company from the owners’ perspective.
Total Assets (Asset Base)
The full value of everything the company owns, including cash, inventory, equipment, and investments. It is needed to understand the resource base used to generate revenue.
Income Before Tax (Pre-Tax Earnings)
Income before provision for income taxes. It is needed to analyze profitability independent of tax structures.
⚙️ Cost & Drag Factors
Cost of Revenue (Production Cost)
Direct costs required to produce and deliver the products or services sold. It is needed to assess efficiency in production and service delivery.
Total Operating Expenses (Operating Cost)
Indirect costs of running the business such as salaries, marketing, and administration. It is needed to understand how much it costs to sustain ongoing business operations.
Income Tax Expense (Tax Drag)
Amount of taxes paid or payable to the government. It is needed to evaluate the impact of taxation on overall profitability.
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