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AKRO
Upturn stock ratingUpturn stock rating

Akero Therapeutics Inc (AKRO)

Upturn stock ratingUpturn stock rating
$53.36
Last Close (24-hour delay)
Profit since last BUY11.1%
upturn advisory
Consider higher Upturn Star rating
BUY since 22 days
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  • SELL Advisory (Loss)​
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Upturn Stock infoUpturn Stock info Stock price based on last close
*as per simulation
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Time period over
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Upturn Advisory Summary

06/30/2025: AKRO (1-star) has a low Upturn Star Rating. Not recommended to BUY.

Upturn Star Rating

rating

Not Recommended Performance

These Stocks/ETFs, based on Upturn Advisory, consistently fall short of market performance, signaling caution before investing.

Number of Analysts

rating

12 Analysts rated it

Well-followed company, solid analyst reports, reliable data for confident investing.

1 Year Target Price $76.3

1 Year Target Price $76.3

Analysts Price Target For last 52 week
$76.3Target price
Low$21.02
Current$53.36
high$58.4

Analysis of Past Performance

Type Stock
Historic Profit -37.91%
Avg. Invested days 28
Today’s Advisory Consider higher Upturn Star rating
Upturn Star Rating Upturn stock ratingUpturn stock rating
Upturn Advisory Performance Upturn Advisory Performance 2.0
Stock Returns Performance Upturn Returns Performance 1.0
Upturn Profits based on simulationUpturn Profits based on simulation Profits based on simulation
Upturn Profits based on simulationUpturn Profits based on simulation Last Close 06/30/2025

Key Highlights

Company Size Mid-Cap Stock
Market Capitalization 4.48B USD
Price to earnings Ratio -
1Y Target Price 76.3
Price to earnings Ratio -
1Y Target Price 76.3
Volume (30-day avg) 12
Beta -0.16
52 Weeks Range 21.02 - 58.40
Updated Date 06/30/2025
52 Weeks Range 21.02 - 58.40
Updated Date 06/30/2025
Dividends yield (FY) -
Basic EPS (TTM) -3.75

Earnings Date

Report Date -
When -
Estimate -
Actual -

Profitability

Profit Margin -
Operating Margin (TTM) -

Management Effectiveness

Return on Assets (TTM) -18.52%
Return on Equity (TTM) -27.92%

Valuation

Trailing PE -
Forward PE -
Enterprise Value 3835587076
Price to Sales(TTM) -
Enterprise Value 3835587076
Price to Sales(TTM) -
Enterprise Value to Revenue -
Enterprise Value to EBITDA -6.77
Shares Outstanding 79717600
Shares Floating 66004554
Shares Outstanding 79717600
Shares Floating 66004554
Percent Insiders 1.39
Percent Institutions 109.29

Analyst Ratings

Rating 4
Target Price 76.3
Buy 3
Strong Buy 9
Buy 3
Strong Buy 9
Hold -
Sell -
Strong Sell -
Strong Sell -

ai summary icon Upturn AI SWOT

Akero Therapeutics Inc

stock logo

Company Overview

overview logo History and Background

Akero Therapeutics, Inc. is a clinical-stage biopharmaceutical company focused on developing transformative treatments for patients with serious metabolic diseases, including non-alcoholic steatohepatitis (NASH). It was founded in 2017. The company's lead product candidate is efruxifermin (EFX).

business area logo Core Business Areas

  • NASH Drug Development: Akero's primary focus is on the research, development, and commercialization of therapies for NASH and other metabolic diseases. This includes clinical trials, regulatory submissions, and potential future manufacturing and marketing activities.

leadership logo Leadership and Structure

Andrew Cheng, M.D., Ph.D., is the President and CEO. The company has a board of directors and a management team overseeing research, development, clinical trials, finance, and other key functions.

Top Products and Market Share

overview logo Key Offerings

  • Efruxifermin (EFX): EFX is Akero's lead product candidate, a fibroblast growth factor 21 (FGF21) analogue being developed for the treatment of NASH. It is currently in Phase 2b/3 clinical trials. There is no current revenue from this product since it is not yet approved. Competitors include Viking Therapeutics (VKTX), Madrigal Pharmaceuticals (MDGL), 89bio (ETNB).

Market Dynamics

industry overview logo Industry Overview

The NASH market is a large and rapidly growing market due to the increasing prevalence of obesity and diabetes, which are risk factors for NASH. There are currently limited approved treatments for NASH, creating a significant unmet medical need.

Positioning

Akero aims to be a leader in the NASH treatment space with EFX, which has shown promising results in clinical trials. The company's FGF21 analogue approach differentiates it from some competitors.

Total Addressable Market (TAM)

The NASH market is estimated to be tens of billions of dollars. Akero, if successful, is positioned to capture a significant portion of the TAM with EFX.

Upturn SWOT Analysis

Strengths

  • Promising clinical trial data for EFX
  • Experienced management team
  • Strong intellectual property position
  • Focused approach on NASH

Weaknesses

  • Dependence on successful development and approval of EFX
  • High cash burn rate
  • No currently approved products
  • Potential for clinical trial setbacks

Opportunities

  • Potential for accelerated regulatory approval
  • Partnerships with larger pharmaceutical companies
  • Expansion into other metabolic disease indications
  • Acquisition by a larger pharmaceutical company

Threats

  • Competition from other companies developing NASH treatments
  • Regulatory hurdles
  • Clinical trial failures
  • Pricing and reimbursement pressures

Competitors and Market Share

competitor logo Key Competitors

  • MDGL
  • VKTX
  • ETNB

Competitive Landscape

Akero has a competitive FGF21 analogue approach with promising data. Competition is stiff from larger pharma and other biotech companies with different mechanisms of action.

Growth Trajectory and Initiatives

Historical Growth: Historically, growth is defined by expansion of the clinical trials. As of now there are no marketable products

Future Projections: Future growth is dependent on the successful commercialization of EFX and expansion into other metabolic disease indications. Analyst projections vary, but generally anticipate significant revenue growth upon potential approval of EFX.

Recent Initiatives: Recent initiatives include progressing EFX through Phase 2b/3 clinical trials and preparing for potential regulatory submissions.

Summary

Akero Therapeutics is a clinical-stage biopharmaceutical company focused on NASH. Its lead drug, efruxifermin, shows promise but faces competition and regulatory hurdles. The company has a strong financial position to continue clinical trials, but its future is tied to the success of EFX. It requires successful navigation of clinical trials and regulatory processes to realize its potential.

Peer Comparison

Sources and Disclaimers

Data Sources:

  • Company SEC Filings, Company Website, Analyst Reports (Yahoo Finance, Google Finance, etc.)

Disclaimers:

This analysis is for informational purposes only and should not be considered investment advice. Investment decisions should be made based on individual research and consultation with a qualified financial advisor. Market share estimates are approximate and subject to change.

Upturn AI SummarizationUpturn AI Summarization AI Summarization is directionally correct and might not be accurate.

Upturn AI SummarizationUpturn AI Summarization Summarized information shown could be a few years old and not current.

Upturn AI SummarizationUpturn AI Summarization Fundamental Rating based on AI could be based on old data.

Upturn AI SummarizationUpturn AI Summarization AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.

About Akero Therapeutics Inc

Exchange NASDAQ
Headquaters South San Francisco, CA, United States
IPO Launch date 2019-06-20
President, CEO & Director Dr. Andrew Cheng M.D., Ph.D.
Sector Healthcare
Industry Biotechnology
Full time employees 69
Full time employees 69

Akero Therapeutics, Inc. engages in the development of treatments for patients with serious metabolic diseases in the United States. The company's lead product candidate is efruxifermin (EFX), an analog of fibroblast growth factor 21 that protects against cellular stress and regulates the metabolism of lipids, carbohydrates, and proteins throughout the body for the treatment of metabolic dysfunction-associated steatohepatitis (MASH) patients. It has a license agreement with Amgen Inc. to develop, manufacture, use, distribute, and sell EFX as a treatment for MASH and other metabolic diseases. The company was formerly known as Pippin Pharmaceuticals, Inc. and changed its name to Akero Therapeutics, Inc. in May 2018. Akero Therapeutics, Inc. was incorporated in 2017 and is headquartered in South San Francisco, California.