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Alto Neuroscience, Inc. (ANRO)

Upturn stock ratingUpturn stock rating
$3.81
Last Close (24-hour delay)
Profit since last BUY37.05%
upturn advisory
Consider higher Upturn Star rating
BUY since 30 days
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Upturn Stock infoUpturn Stock info Stock price based on last close
*as per simulation
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Upturn Advisory Summary

08/28/2025: ANRO (1-star) has a low Upturn Star Rating. Not recommended to BUY.

Upturn Star Rating

rating

Not Recommended Performance

These Stocks/ETFs, based on Upturn Advisory, consistently fall short of market performance, signaling caution before investing.

Number of Analysts

rating

8 Analysts rated it

Limited analyst coverage, niche firm, research info may be scarce.

1 Year Target Price $10.33

1 Year Target Price $10.33

Analysts Price Target For last 52 week
$10.33 Target price
52w Low $1.6
Current$3.81
52w High $15.04

Analysis of Past Performance

Type Stock
Historic Profit -85.78%
Avg. Invested days 18
Today’s Advisory Consider higher Upturn Star rating
Upturn Star Rating Upturn stock ratingUpturn stock rating
Upturn Advisory Performance Upturn Advisory Performance 2.0
Stock Returns Performance Upturn Returns Performance 1.0
Upturn Profits based on simulationUpturn Profits based on simulation Profits based on simulation
Upturn Profits based on simulationUpturn Profits based on simulation Last Close 08/28/2025

Key Highlights

Company Size Small-Cap Stock
Market Capitalization 103.16M USD
Price to earnings Ratio -
1Y Target Price 10.33
Price to earnings Ratio -
1Y Target Price 10.33
Volume (30-day avg) 8
Beta -
52 Weeks Range 1.60 - 15.04
Updated Date 08/29/2025
52 Weeks Range 1.60 - 15.04
Updated Date 08/29/2025
Dividends yield (FY) -
Basic EPS (TTM) -2.39

Earnings Date

Report Date 2025-08-13
When -
Estimate -0.6
Actual -0.65

Profitability

Profit Margin -
Operating Margin (TTM) -

Management Effectiveness

Return on Assets (TTM) -24.72%
Return on Equity (TTM) -42.79%

Valuation

Trailing PE -
Forward PE -
Enterprise Value -17114044
Price to Sales(TTM) -
Enterprise Value -17114044
Price to Sales(TTM) -
Enterprise Value to Revenue -
Enterprise Value to EBITDA -
Shares Outstanding 27076600
Shares Floating 17884113
Shares Outstanding 27076600
Shares Floating 17884113
Percent Insiders 7.48
Percent Institutions 64.06

ai summary icon Upturn AI SWOT

Alto Neuroscience, Inc.

stock logo

Company Overview

overview logo History and Background

Alto Neuroscience, Inc. is a clinical-stage biopharmaceutical company focused on developing precision therapies for mental health. Founded to address the significant unmet need in treating mental illnesses by leveraging neurobiological data to identify patients most likely to respond to specific treatments.

business area logo Core Business Areas

  • Drug Development: Focuses on the research, development, and clinical trials of novel therapeutics for various mental health conditions.
  • Precision Psychiatry Platform: Utilizes brain biomarkers, such as EEG activity and cognitive assessments, to identify patient subgroups and predict treatment response.

leadership logo Leadership and Structure

The leadership team includes experienced professionals in drug development, neuroscience, and business management. The company's structure includes research and development, clinical operations, and commercial strategy divisions.

Top Products and Market Share

overview logo Key Offerings

  • ALTO-100: A novel compound in clinical development for major depressive disorder (MDD). Market share is currently N/A as it's not yet approved. Competitors include SSRIs and other antidepressants from companies like Eli Lilly (LLY) and Pfizer (PFE).
  • ALTO-203: Being developed for PTSD. Market share is N/A, as it is in clinical trials. Competitors include drugs from companies like Bausch Health Companies (BHC) and generic versions of existing treatments.

Market Dynamics

industry overview logo Industry Overview

The mental health therapeutics market is large and growing, driven by increased awareness, diagnosis rates, and the need for more effective treatments. There's a growing emphasis on precision medicine approaches to improve treatment outcomes.

Positioning

Alto Neuroscience is positioned as a leader in precision psychiatry, using biomarkers to develop targeted therapies. This differentiates them from traditional pharmaceutical companies that rely on a broader approach.

Total Addressable Market (TAM)

The global mental health market is estimated at hundreds of billions of dollars. Alto Neuroscience is positioned to capture a significant share of this market by developing more effective and targeted treatments.

Upturn SWOT Analysis

Strengths

  • Proprietary precision psychiatry platform
  • Strong focus on biomarker-driven drug development
  • Experienced management team
  • Pipeline of novel drug candidates

Weaknesses

  • Clinical trial risks
  • High R&D expenses
  • Reliance on successful clinical trial outcomes
  • Limited commercialization experience

Opportunities

  • Partnerships with pharmaceutical companies
  • Expansion of the precision psychiatry platform to other therapeutic areas
  • Increased adoption of biomarker-based diagnostics
  • Growing demand for personalized mental health treatments

Threats

  • Regulatory hurdles
  • Competition from established pharmaceutical companies
  • Failure of clinical trials
  • Reimbursement challenges

Competitors and Market Share

competitor logo Key Competitors

  • Eli Lilly (LLY)
  • Pfizer (PFE)
  • Bausch Health Companies (BHC)

Competitive Landscape

Alto Neuroscience differentiates itself through its precision psychiatry approach. Competitors have established products and market share, but Alto's focus on biomarkers may provide a competitive advantage in the long run.

Growth Trajectory and Initiatives

Historical Growth: N/A due to limited operating history as a public entity.

Future Projections: Future growth is dependent on successful clinical trials and regulatory approvals. Analyst estimates will become available post-IPO.

Recent Initiatives: Focusing on advancing its clinical pipeline, securing partnerships, and expanding its precision psychiatry platform.

Summary

Alto Neuroscience is a promising clinical-stage company focused on precision psychiatry, leveraging biomarkers for targeted mental health treatments. Its success hinges on positive clinical trial results and regulatory approvals. The company faces competition from established pharmaceutical players but has a unique approach that could drive future growth and requires funding to sustain.

Peer Comparison

Sources and Disclaimers

Data Sources:

  • Company Website
  • Industry Reports
  • ClinicalTrials.gov
  • SEC Filings (Post IPO)

Disclaimers:

This analysis is based on currently available information and is subject to change. Market share data are estimates. Investment decisions should be based on thorough research and consultation with a financial advisor.

Upturn AI SummarizationUpturn AI Summarization AI Summarization is directionally correct and might not be accurate.

Upturn AI SummarizationUpturn AI Summarization Summarized information shown could be a few years old and not current.

Upturn AI SummarizationUpturn AI Summarization Fundamental Rating based on AI could be based on old data.

Upturn AI SummarizationUpturn AI Summarization AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.

About Alto Neuroscience, Inc.

Exchange NYSE
Headquaters Mountain View, CA, United States
IPO Launch date 2024-02-02
Founder, Chairman of the Board, CEO & President Dr. Amit Etkin M.D., Ph.D.
Sector Healthcare
Industry Biotechnology
Full time employees 76
Full time employees 76

Alto Neuroscience, Inc. operates as a clinical-stage biopharmaceutical company in the United States. The company's product pipeline includes ALTO-100, which is in Phase 2b clinical trial for the treatment of patients with bipolar depression (BPD). It also develops ALTO-300, a small molecule melatonergic agonist and serotonergic antagonist with antidepressant properties, which is in Phase 2b clinical trial to treat patients with major depressive disorder (MDD); ALTO-101, a novel small molecule phosphodiesterase 4 inhibitor that is in Phase 2 proof-of-concept (POC) trial for the treatment of cognitive impairment associated with schizophrenia; ALTO-203, a novel small-molecule histamine H3 receptor inverse agonist, which is in Phase 2 POC trial to treat patients with MDD and higher levels of anhedonia; and ALTO-202, an investigational orally bioavailable antagonist of the GluN2B subunit of the NMDA receptor that is in Phase 1 clinical trial for the treatment of MDD. The company was incorporated in 2019 and is headquartered in Mountain View, California.