Ardelyx Inc logo

Ardelyx Inc(ARDX)

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ADVISORIES YOU CAN VERIFY
QUALITY SIGNAL
3-STAR RATING
PASS
LAST CLOSE
$3.41
09/28/2026
(24-hour delay)

Advisory History & Simulated Performance *

*as per simulation (see disclosures)
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Upturn Advisory & Investor View for ARDX

09/28/2026: ARDX (3-star) is currently NOT-A-BUY. Pass it for now.

Ardelyx is a commercial-stage biotechnology company focused on developing therapies for cardiorenal and gastrointestinal diseases, most notably through its FDA-approved products IBSRELA and XPHOZAH. The company's main strength lies in its ability to bring first-in-class, non-systemic small molecule therapies to market, creating a differentiated niche in competitive therapeutic areas. Its primary growth story centers on the continued market adoption and expansion of these two products. However, investors must monitor significant risks, including intense competition from established pharmaceutical incumbents and the challenge of reaching consistent profitability. Ardelyx may best suit growth-oriented investors with a high risk tolerance for the volatile nature of the biotech sector.

How to Read the Upturn Advisory

The Upturn Star Rating and the current BUY, SELL, or PASS advisory are generated by Upturn’s AI advisory engine based on proprietary signal analysis, price behavior, advisory history, and historical signal performance.

Company fundamentals, valuation, risks, and news provide supporting context about the business.

Investor Fit

Investor styleFitWhy
Growth investorStrong fitThe company is in an active commercial expansion phase with significant potential for revenue scaling.
Momentum investorMixed fitMomentum appeal depends on positive market adoption signals and successful execution of sales targets.
Value investorWeak fitThe company is not yet consistently profitable, making traditional value metrics like P/E difficult to apply.
Dividend investorWeak fitThe company is focused on growth and reinvestment, not income distribution.
Low-risk investorWeak fitSmall-cap biotech stocks inherently carry high volatility and execution risk.

Risk Profile

Risk factorLevelWhy it matters
Price volatilityHighBiotech stocks are highly sensitive to clinical, regulatory, and commercial updates.
Valuation riskMedium / highInvestors often pay for future growth that is sensitive to commercial execution.
Competition risk (pharmaceutical incumbents)HighLarge incumbents have significant resources to defend their market share.
Business qualityMediumThe business is transitioning well but still lacks a long track record of sustained profitability.
Dividend incomeLow / noneThe company does not provide income, only capital appreciation potential.
Execution riskHighSuccess relies heavily on the continued adoption of IBSRELA and XPHOZAH in competitive markets.

Price Behavior

Steep Decline
PRICE PATH

Steep Decline

The stock price has dropped sharply with strong downward pressure.

Choppy
PRICE STABILITY

Choppy

The stock has experienced frequent reversals and pronounced short-term price swings.

Analysis of Past Performance

Type Stock
Historic Profit 128.3%
Avg. Invested days 36
Today’s Advisory PASS
Upturn Advisory Rating upturn star rating icon
Upturn Advisory Performance Upturn Advisory Performance icon 3.0
Stock Returns Performance Upturn Returns Performance icon 5.0
Upturn Profits based on simulation icon Profits based on simulation
Upturn last close icon Last Close 09/28/2026

Upturn Scorecard

Upturn Star Rating

★★★★★
ARDX receives a 3-star rating, supported by solid analyst coverage. The rating is constrained by weak unit economics, and weak price momentum.

Company Fundamentals

★★★★★
ARDX has moderate overall fundamentals (3 stars), with moderate financial health, moderate growth momentum, and solid ownership. In FY2025 versus FY2024, solid revenue growth (+22.1%) is partially offset by negative earnings growth (-57.4%), weak cash generation (FCF margin -10.8%), weak profitability (net margin -15.1%).

Financial Health Rating

★★★★★
ARDX's financial health is supported by solid liquidity, including working-capital and asset support (WC/assets 58.6%). Cash strength is soft (2 stars), which helps explain the 3-star overall score.

Growth Momentum Score

★★★★★
Revenue growth is ARDX's strongest growth driver at +22.1% FY2025 versus FY2024 (solid, 4 stars). By comparison, while earnings growth (-57.4%, negative) holds the profile back, so recent growth is not broad-based across the business.

Ownership

★★★★★
Institutional ownership is 73.2% and approximately 81.6% of outstanding shares are publicly tradable, supporting liquidity and institutional participation. Insider ownership of 3.17% provides only moderate management-shareholder alignment.

Top 5 Institutional Investors

BlackRock Inc 8.20%
Millennium Management LLC 5.38%
State Street Corp 5.27%
Vanguard Capital Management, LLC 4.01%
HHG PLC 3.24%

Unit Economics (Per $1K Revenue)

★★★★★
ARDX generates approximately $895 of gross profit, $-101 of operating income, and $-108 of free cash flow for every $1,000 of revenue. Based on FY2025 results. Operating losses and cash burn explain the 1-star rating, with weak cash conversion and weak capital efficiency.

Economic Dimensions

★★★★★
Effective Tax Rate: -1.60% (Tax Credit)

Quantitative Style Profile

★★★★★
ARDX has a liquid, relatively low-volatility profile. Weak momentum is the primary drawback, while valuation that is moderately attractive rather than deeply discounted.

Style Classification

Quality Focused

Low VolatilitySmall / Mid Cap RiskShort Squeeze RiskHighly Liquid / Institution-Friendly

Key Highlights

Company Size Small-Cap Stock
Market Capitalization 883.00M USD
Price to earnings Ratio -
1Y Target Price 12.9
Price to earnings Ratio -
1Y Target Price 12.9
Volume (30-day avg) 4.0M shares
Beta 0.69
52 Weeks Range 3.33 - 8.40
Updated Date 09/27/2026
52 Weeks Range 3.33 - 8.40
Updated Date 09/27/2026
Dividends yield (FY) -
Basic EPS (TTM) -0.23

How Company Makes Money

Business areaWhat it includesRetail investor read
Product RevenueDirect sales of IBSRELA and XPHOZAH to specialty pharmacies and distributors.The company earns money by selling its two FDA-approved drugs directly to the healthcare market.
Collaboration and LicensingRevenue from licensing agreements or partnerships for international markets.Additional revenue may come from licensing its drug technology to partners in other regions.

Analyzing Revenue: Products, Geography and Growth

Revenue by Products

Product revenue - Year on Year

Revenue by Geography

Geography revenue - Year on Year

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Valuation

Trailing PE -
Forward PE 9.93
Enterprise Value 871.56M
Price to Sales(TTM) 1.96
Enterprise Value 871.56M
Price to Sales(TTM) 1.96
Enterprise Value to Revenue 1.93
Enterprise Value to EBITDA 130.88
Shares Outstanding 258.19M
Shares Floating 210.66M
Shares Outstanding 258.19M
Shares Floating 210.66M
Percent Insiders 3.17
Percent Institutions 73.22

Icon representing Upturn AI-generated SWOT analysis summary Upturn AI Summary

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Financial Metrics

🧭 Investment Snapshot

Total Revenue (Scale)

Information icon Total money earned from selling products or services before any costs. It is needed to understand the scale of the business and its ability to generate income.

Net Income (Profit)

Information icon Final profit after all expenses, interest, and taxes are deducted. It is needed to determine the overall profitability available to shareholders.

Free Cash Flow (Cash Strength)

Information icon Cash remaining after operating activities and capital expenditures, showing cash available for growth. It is needed to evaluate the company’s ability to invest, pay dividends, or reduce debt.

📈 Growth & Strength

Operating Income (Core Profit)

Information icon Profit from core operations after deducting all operating expenses. It is needed to measure how efficiently the company runs its primary business activities.

EBITDA (Cash Earnings)

Information icon Earnings before interest, taxes, depreciation, and amortization, indicating operating cash potential. It is needed to compare operating performance across companies without accounting or financing differences.

Gross Profit (Unit Profitability)

Information icon Revenue minus cost of revenue, showing profit after direct production costs. It is needed to evaluate core business profitability before overhead expenses.

🛡️ Financial Safety

Cash (Liquidity Buffer)

Information icon Total cash and cash equivalents on hand. It is needed to evaluate immediate liquidity and financial flexibility.

Total Debt (Leverage Risk)

Information icon Total debt including both short-term and long-term components. It is needed to assess the company’s leverage and financial risk.

Net Working Capital (Short-Term Health)

Information icon Current assets minus current liabilities, indicating short-term liquidity strength. It is needed to assess whether the company can meet its short-term obligations.

🧱 Balance Sheet Strength

Stockholder Equity (Net Worth)

Information icon Total equity value held by shareholders. It is needed to understand the net worth of the company from the owners’ perspective.

Total Assets (Asset Base)

Information icon The full value of everything the company owns, including cash, inventory, equipment, and investments. It is needed to understand the resource base used to generate revenue.

Income Before Tax (Pre-Tax Earnings)

Information icon Income before provision for income taxes. It is needed to analyze profitability independent of tax structures.

⚙️ Cost & Drag Factors

Cost of Revenue (Production Cost)

Information icon Direct costs required to produce and deliver the products or services sold. It is needed to assess efficiency in production and service delivery.

Total Operating Expenses (Operating Cost)

Information icon Indirect costs of running the business such as salaries, marketing, and administration. It is needed to understand how much it costs to sustain ongoing business operations.

Income Tax Expense (Tax Drag)

Information icon Amount of taxes paid or payable to the government. It is needed to evaluate the impact of taxation on overall profitability.

About Ardelyx Inc

Exchange NASDAQ
Headquarters Waltham, MA, United States
IPO Launch date 2014-06-19
President, CEO & Director Mr. Michael G. Raab
Sector Healthcare
Industry Biotechnology
Full time employees 489
Full time employees 489

Ardelyx, Inc. discovers, develops, and commercializes medicines to treat unmet medical needs in the United States and internationally. The company offers IBSRELA, a minimally absorbed small molecule therapy for the treatment of patients with irritable bowel syndrome with constipation; and XPHOZAH, a phosphate absorption inhibitor to reduce serum phosphorus in adults with chronic kidney disease on dialysis. Ardelyx, Inc. was formerly known as Nteryx, Inc. and changed its name to Ardelyx, Inc. in June 2008. The company was incorporated in 2007 and is headquartered in Waltham, Massachusetts.