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Takeda Pharmaceutical Co Ltd ADR (TAK)

Upturn stock ratingUpturn stock rating
$15.06
Last Close (24-hour delay)
Profit since last BUY-2.71%
upturn advisory
Consider higher Upturn Star rating
BUY since 18 days
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Upturn Stock infoUpturn Stock info Stock price based on last close
*as per simulation
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Time period over
  • ALL
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Upturn Advisory Summary

09/15/2025: TAK (1-star) has a low Upturn Star Rating. Not recommended to BUY.

Upturn Star Rating

rating

Not Recommended Performance

These Stocks/ETFs, based on Upturn Advisory, consistently fall short of market performance, signaling caution before investing.

Number of Analysts

rating

4 Analysts rated it

Very few follow this stock; limited insights, higher-risk early investing.

1 Year Target Price $18.36

1 Year Target Price $18.36

Analysts Price Target For last 52 week
$18.36 Target price
52w Low $12.51
Current$15.06
52w High $15.69

Analysis of Past Performance

Type Stock
Historic Profit -13.6%
Avg. Invested days 28
Today’s Advisory Consider higher Upturn Star rating
Upturn Star Rating Upturn stock ratingUpturn stock rating
Upturn Advisory Performance Upturn Advisory Performance 2.0
Stock Returns Performance Upturn Returns Performance 1.0
Upturn Profits based on simulationUpturn Profits based on simulation Profits based on simulation
Upturn Profits based on simulationUpturn Profits based on simulation Last Close 09/15/2025

Key Highlights

Company Size Large-Cap Stock
Market Capitalization 48.19B USD
Price to earnings Ratio 51.93
1Y Target Price 18.36
Price to earnings Ratio 51.93
1Y Target Price 18.36
Volume (30-day avg) 4
Beta 0.27
52 Weeks Range 12.51 - 15.69
Updated Date 09/15/2025
52 Weeks Range 12.51 - 15.69
Updated Date 09/15/2025
Dividends yield (FY) 4.40%
Basic EPS (TTM) 0.29

Analyzing Revenue: Products, Geography and Growth

Revenue by Products

Product revenue - Year on Year

Revenue by Geography

Geography revenue - Year on Year

Earnings Date

Report Date -
When -
Estimate -
Actual -

Profitability

Profit Margin 3.06%
Operating Margin (TTM) 16.89%

Management Effectiveness

Return on Assets (TTM) 2.31%
Return on Equity (TTM) 1.87%

Valuation

Trailing PE 51.93
Forward PE 14.84
Enterprise Value 75948758000
Price to Sales(TTM) 0.01
Enterprise Value 75948758000
Price to Sales(TTM) 0.01
Enterprise Value to Revenue 2.5
Enterprise Value to EBITDA 9.94
Shares Outstanding 3158220032
Shares Floating 1561025417
Shares Outstanding 3158220032
Shares Floating 1561025417
Percent Insiders 0.01
Percent Institutions 2.51

ai summary icon Upturn AI SWOT

Takeda Pharmaceutical Co Ltd ADR

stock logo

Company Overview

overview logo History and Background

Takeda Pharmaceutical Company Limited was founded in 1781 in Osaka, Japan. Initially a medicine wholesaler, it evolved into a global pharmaceutical company through organic growth and strategic acquisitions.

business area logo Core Business Areas

  • Gastroenterology: Focuses on treatments for gastrointestinal disorders such as inflammatory bowel disease (IBD) and short bowel syndrome (SBS).
  • Rare Diseases: Develops and markets therapies for rare genetic and hematologic diseases.
  • Plasma-Derived Therapies: Offers plasma-derived products for immune deficiencies, bleeding disorders, and other conditions.
  • Oncology: Develops therapies for various types of cancer, including hematologic malignancies and solid tumors.
  • Neuroscience: Focuses on treatments for neurological and psychiatric disorders, such as ADHD and depression.

leadership logo Leadership and Structure

Takeda is led by Christophe Weber (CEO). The organizational structure includes global business units and regional operations.

Top Products and Market Share

overview logo Key Offerings

  • Entyvio: An integrin receptor antagonist used to treat ulcerative colitis and Crohn's disease. Competitors include: Stelara (JNJ), Humira (ABBV), Remicade (JNJ). 2023 Revenue: ~ $5 Billion. Market share is estimated at around 20% of the IBD biologics market.
  • Vyvanse/Elvanse: A central nervous system stimulant used to treat ADHD and binge eating disorder (marketed as Elvanse outside of the US). Competitors: Adderall (multiple generics), Concerta (JNJ). 2023 revenue ~$2.5 Billion. The market share is estimated at around 15% in the ADHD market.
  • Livtencity: An antiviral drug approved for post-transplant cytomegalovirus (CMV) infection. Competitors: Letermovir (Merck), Ganciclovir (multiple generics). 2023 revenue ~$200 Million. Estimated to grow to be a blockbuster drug. Market share is estimated around 40% in treating drug resistant CMV infections.

Market Dynamics

industry overview logo Industry Overview

The pharmaceutical industry is characterized by intense competition, high R&D costs, stringent regulatory requirements, and increasing pressure on pricing.

Positioning

Takeda is a global, research-driven pharmaceutical company with a focus on innovative medicines. It competes with large multinational corporations and smaller biotech firms.

Total Addressable Market (TAM)

The global pharmaceutical market is valued at over $1.4 trillion and is expected to continue to grow. Takeda is well positioned to capitalize on this growth through its diverse portfolio and focus on innovation.

Upturn SWOT Analysis

Strengths

  • Global Presence
  • Diversified Portfolio
  • Strong R&D Capabilities
  • Established Brands
  • Experienced Management Team

Weaknesses

  • High Debt Levels (related to Shire acquisition)
  • Patent Expiry Risks
  • Dependence on Key Products
  • Integration Challenges (Shire acquisition)
  • Generic Competition

Opportunities

  • Expansion into Emerging Markets
  • Development of New Therapies
  • Strategic Acquisitions
  • Collaboration with Biotech Firms
  • Growth in Personalized Medicine

Threats

  • Increased Competition
  • Pricing Pressures
  • Regulatory Changes
  • Economic Downturns
  • Patent Challenges

Competitors and Market Share

competitor logo Key Competitors

  • JNJ
  • MRK
  • PFE
  • ABBV
  • NVS

Competitive Landscape

Takeda faces intense competition from larger pharmaceutical companies. It differentiates itself through its focus on specific therapeutic areas and its global presence.

Major Acquisitions

Shire

  • Year: 2019
  • Acquisition Price (USD millions): 62000
  • Strategic Rationale: Expanded Takeda's portfolio in rare diseases and strengthened its global presence.

Nimbus Lakshmi, Inc

  • Year: 2023
  • Acquisition Price (USD millions): 4000
  • Strategic Rationale: Acquiring Nimbus Lakshmi reinforces Takedau2019s commitment to GI and creates an exciting opportunity to potentially bring best-in-class targeted therapies to patients living with Crohnu2019s disease.

Growth Trajectory and Initiatives

Historical Growth: Growth has been driven by key products and strategic acquisitions, particularly the acquisition of Shire.

Future Projections: Analysts expect continued growth, driven by new product launches and expansion into emerging markets.

Recent Initiatives: Recent initiatives include focusing on core therapeutic areas, divesting non-core assets, and investing in R&D.

Summary

Takeda is a global pharmaceutical company with a strong presence in key therapeutic areas, driven by innovative medicines and strategic acquisitions. While the Shire acquisition increased its debt, it also expanded its portfolio. Takeda needs to manage its debt, navigate generic competition, and capitalize on opportunities in emerging markets and personalized medicine. Takeda's success depends on continued investment in research and development and strategic execution.

Peer Comparison

Sources and Disclaimers

Data Sources:

  • Company Filings (SEC)
  • Analyst Reports (e.g., Reuters, Bloomberg)
  • Company Website
  • Industry Reports

Disclaimers:

This analysis is for informational purposes only and does not constitute financial advice. Investment decisions should be based on individual due diligence.

Upturn AI SummarizationUpturn AI Summarization AI Summarization is directionally correct and might not be accurate.

Upturn AI SummarizationUpturn AI Summarization Summarized information shown could be a few years old and not current.

Upturn AI SummarizationUpturn AI Summarization Fundamental Rating based on AI could be based on old data.

Upturn AI SummarizationUpturn AI Summarization AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.

About Takeda Pharmaceutical Co Ltd ADR

Exchange NYSE
Headquaters -
IPO Launch date 2008-10-27
President, CEO & Representative Director Mr. Christophe Weber
Sector Healthcare
Industry Drug Manufacturers - Specialty & Generic
Full time employees 47455
Full time employees 47455

Takeda Pharmaceutical Company Limited engages in the research, development, manufacture, marketing, and out-licensing of pharmaceutical products in Japan and internationally. It offers pharmaceutical products in the areas of gastroenterology, rare diseases, plasma derived therapies, immunology, oncology, and neuroscience. The company provides its products under the Entyvio, Gattex/Revestive, Takecab/Vocinti, EOHILIA, Alofisel, Dexilant, Pantoloc/Controloc, Adynovate/Adynovi, Feiba, Recombinate, Hemofil/Immunate/Immunine, Takhzyro, Livtencity, ADZYNMA, Elaprase, Replagal, Advate, Flexbumin, Vpriv, Gammagard Liquid/Kiovig, Hyqvia, Cuvitru, Exkivity, FRUZAQLA, Ninlaro, Velcade, Azilva-F, Lotriga, Iclusig, Leuplin/Enantone, Adcetris, vyvanse/elvanse, Trintellix, QDENGA, and Alunbrig brands. It has in-license agreement with BioMarin, Luxna Biotech, GlaxoSmithKline, Halozyme, and Kamada; collaboration with Neurocrine Biosciences, Inc., Seagen Inc., Anima Biotech, Denali Therapeutics, KSQ Therapeutics, Noile-Immune Biotech, Center for iPS Cell Research Application, Kyoto University (CiRA), and Charles River Laboratories; licensing agreement with Mirum Pharmaceuticals and Twist Bioscience, UCSD/Fortis Advisors, PeptiDream, MD Anderson Cancer Center, Teva Pharmaceutical Industries, and Xenetic Biosciences; collaboration and licensing agreement with Arrowhead Pharmaceuticals Inc., Engitix, Genevant Sciences Corporation, Sosei Heptares, Zedira/Dr. Falk Pharma, Exelixis, Inc., GlaxoSmithKline, Heidelberg Pharma, HUTCHMED, Presage Biosciences, Codexis, Inc., Ensoma, Envozyne, KM Biologics, and Selecta BioScience, and Ovid Therapeutics Inc.; and collaboration with ZEDIRA GmbH and Dr. Falk Pharma GmbH. It has research collaboration and licensing agreement with Crescendo Biologics, Code Bio, Immusoft, Poseida Therapeutics, and Selecta Biosciences. The company was founded in 1781 and is headquartered in Tokyo, Japan.