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BioLineRx Ltd (BLRX)



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Upturn Advisory Summary
09/16/2025: BLRX (1-star) is currently NOT-A-BUY. Pass it for now.
1 Year Target Price $26
1 Year Target Price $26
1 | Strong Buy |
1 | Buy |
0 | Hold |
0 | Sell |
0 | Strong Sell |
Analysis of Past Performance
Type Stock | Historic Profit 23.62% | Avg. Invested days 32 | Today’s Advisory PASS |
Upturn Star Rating ![]() ![]() | Upturn Advisory Performance ![]() | Stock Returns Performance ![]() |
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Key Highlights
Company Size Small-Cap Stock | Market Capitalization 16.07M USD | Price to earnings Ratio - | 1Y Target Price 26 |
Price to earnings Ratio - | 1Y Target Price 26 | ||
Volume (30-day avg) 2 | Beta 0.89 | 52 Weeks Range 2.30 - 26.80 | Updated Date 09/16/2025 |
52 Weeks Range 2.30 - 26.80 | Updated Date 09/16/2025 | ||
Dividends yield (FY) - | Basic EPS (TTM) -6 |
Earnings Date
Report Date - | When - | Estimate - | Actual - |
Profitability
Profit Margin -45.34% | Operating Margin (TTM) -757.57% |
Management Effectiveness
Return on Assets (TTM) -15.36% | Return on Equity (TTM) -45.94% |
Valuation
Trailing PE - | Forward PE 93.46 | Enterprise Value 1373362 | Price to Sales(TTM) 0.98 |
Enterprise Value 1373362 | Price to Sales(TTM) 0.98 | ||
Enterprise Value to Revenue 0.08 | Enterprise Value to EBITDA 0.7 | Shares Outstanding 4262680 | Shares Floating 2450907651 |
Shares Outstanding 4262680 | Shares Floating 2450907651 | ||
Percent Insiders 4.08 | Percent Institutions 1.55 |
Upturn AI SWOT
BioLineRx Ltd

Company Overview
History and Background
BioLineRx Ltd. is a biopharmaceutical company focused on oncology. Founded in 2003, it initially focused on out-licensing early-stage drug candidates. Over time, it shifted its strategy to developing and commercializing its own pipeline, achieving a significant milestone with the FDA approval of APHARDAu00ae (motixafortide).
Core Business Areas
- Oncology Therapeutics: Focuses on developing and commercializing novel oncology therapies, primarily centered around its lead product, APHARDA (motixafortide).
Leadership and Structure
The leadership team consists of executives with experience in drug development, commercialization, and finance. The company structure is typical of a publicly traded biopharmaceutical company, with a board of directors overseeing management.
Top Products and Market Share
Key Offerings
- APHARDA (motixafortide): A CXCR4 inhibitor approved by the FDA for use in combination with filgrastim to mobilize hematopoietic stem cells to the peripheral blood for collection and subsequent autologous transplantation in patients with multiple myeloma. Market share data is still evolving as APHARDA is a relatively new product. Key competitors include drugs that stimulate hematopoietic stem cell mobilization, such as plerixafor (Mozobil) from Sanofi.
Market Dynamics
Industry Overview
The biopharmaceutical industry, particularly the oncology segment, is characterized by high R&D costs, lengthy regulatory approval processes, and intense competition. The market for stem cell mobilization therapies is driven by the increasing incidence of hematological malignancies and the growing demand for autologous stem cell transplantation.
Positioning
BioLineRx positions itself as a company focused on innovative oncology therapies. APHARDA provides a novel option for stem cell mobilization, addressing a specific need in multiple myeloma treatment.
Total Addressable Market (TAM)
The global stem cell mobilization market is estimated to be in the hundreds of millions USD annually and is expected to grow. BioLineRx is positioned to capture a share of this market with APHARDA.
Upturn SWOT Analysis
Strengths
- FDA-approved product (APHARDA)
- Novel mechanism of action (CXCR4 inhibition)
- Strong IP protection for APHARDA
Weaknesses
- Reliance on a single product (APHARDA)
- Limited commercial infrastructure
- High operating expenses associated with drug development and commercialization
- Need for additional financing
Opportunities
- Expansion of APHARDA label to other indications
- Strategic partnerships for commercialization in new territories
- Development of new pipeline candidates
Threats
- Competition from existing stem cell mobilization therapies
- Potential for generic versions of APHARDA after patent expiry
- Unfavorable regulatory decisions
- Failure to secure additional financing
Competitors and Market Share
Key Competitors
- SNY
- AMGN
Competitive Landscape
BioLineRx faces competition from established pharmaceutical companies with existing stem cell mobilization therapies. APHARDA's novel mechanism of action provides a competitive advantage.
Growth Trajectory and Initiatives
Historical Growth: Growth has been tied to clinical trial progress and regulatory approvals. The approval of APHARDA marks a significant growth milestone.
Future Projections: Future growth depends on the successful commercialization of APHARDA, potential label expansion, and development of new pipeline candidates. Analyst projections vary.
Recent Initiatives: Recent initiatives include launching APHARDA in the US market, pursuing partnerships for ex-US commercialization, and advancing other pipeline programs.
Summary
BioLineRx is a biopharmaceutical company with an FDA-approved product, APHARDA, targeting stem cell mobilization. The company faces challenges related to commercialization, competition, and financing. Success hinges on APHARDA's market penetration and future pipeline development. Securing partnerships and managing cash flow will be crucial.
Peer Comparison
Sources and Disclaimers
Data Sources:
- Company website
- SEC filings
- Press releases
- Analyst reports
Disclaimers:
This analysis is for informational purposes only and does not constitute financial advice. Market share data is estimated and may vary. Please consult with a qualified financial advisor before making any investment decisions.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About BioLineRx Ltd
Exchange NASDAQ | Headquaters - | ||
IPO Launch date 2011-07-25 | CEO - | ||
Sector Healthcare | Industry Biotechnology | Full time employees 28 | Website https://www.biolinerx.com |
Full time employees 28 | Website https://www.biolinerx.com |
BioLineRx Ltd., a commercial stage biopharmaceutical company, develops and commercializes therapeutics for oncology and rare diseases. The company's pipeline includes APHEXDA (motixafortide), a peptide that is in Phase 1 clinical trial for the treatment of sickle cell disease, and Phase 2b clinical trial for the treatment of pancreatic cancer, as well as completed Phase 3 clinical trial for the treatment of multiple myeloma. It develops BL-5010, a pen-like applicator containing an acidic aqueous solution for the non-surgical removal of skin lesions. BioLineRx Ltd. was incorporated in 2003 and is headquartered in Hevel Modi'in, Israel.

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