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Biomea Fusion Inc(BMEA)
Advisory History & Simulated Performance *
*as per simulation (see disclosures)- ALL
- 1Y
- 1M
- 1W
- BUY Advisory
- SELL Advisory (Profit)
- SELL Advisory (Loss)
- Profit
- Loss
- PASS (Skip)
Stock price based on last close Advisory Performance History (Simulated)
Upturn Advisory & Investor View for BMEA
11/09/2026: BMEA (1-star) is currently NOT-A-BUY. Pass it for now.
Biomea Fusion is a clinical-stage biotechnology company focused on developing covalent small molecule medicines for oncology and metabolic conditions. Its main strength lies in its proprietary drug discovery platform, which enables the creation of highly targeted therapies. The investment story centers on the potential for its lead asset, BMF-219, to treat large markets such as diabetes. However, the company faces substantial risks, including the absence of commercial revenue, high development costs, and competition from better-funded peers. This stock is best suited for high-risk investors who can tolerate significant volatility, and stakeholders should closely monitor clinical trial updates and capital management initiatives.
How to Read the Upturn Advisory
The Upturn Star Rating and the current BUY, SELL, or PASS advisory are generated by Upturn’s AI advisory engine based on proprietary signal analysis, price behavior, advisory history, and historical signal performance.
Company fundamentals, valuation, risks, and news provide supporting context about the business.
Investor Fit
| Investor style | Fit | Why |
|---|---|---|
| Growth investor | Mixed fit | The company represents a speculative growth opportunity tied to clinical trial success. |
| Momentum investor | Mixed fit | Momentum is highly dependent on binary clinical trial news flow rather than fundamental performance. |
| Value investor | Weak fit | The lack of revenue and earnings makes traditional value metrics inapplicable. |
| Dividend investor | Weak fit | The company does not pay dividends and requires all cash for development. |
| Low-risk investor | Weak fit | Clinical-stage biotechnology stocks exhibit high volatility and binary risk. |
Risk Profile
| Risk factor | Level | Why it matters |
|---|---|---|
| Price volatility | High | Stock prices for clinical-stage firms react sharply to clinical data announcements. |
| Valuation risk | High | Valuations are speculative and based on long-term potential outcomes. |
| Competition risk (Oncology/Metabolic) | High | Many competitors are targeting the same pathways with well-funded programs. |
| Business quality | Medium | The platform is proprietary, but the business remains pre-revenue. |
| Dividend income | Low / none | No capital return program exists for investors. |
| Execution risk | High | Success depends entirely on the technical and regulatory outcome of clinical trials. |
Price Behavior
Steep Decline
The stock price has dropped sharply with strong downward pressure.
Extreme Price Shocks
The stock has experienced exceptionally large and disruptive price movements during the period.
Analysis of Past Performance
Type Stock | Historic Profit -63.31% | Avg. Invested days 18 | Today’s Advisory PASS |
Upturn Advisory Rating  | Upturn Advisory Performance  2.0 | Stock Returns Performance  1.0 |
| Profits based on simulation | Last Close 11/09/2026 |
Upturn Scorecard
Upturn Star Rating 
Company Fundamentals
Financial Health Rating
Growth Momentum Score
Ownership
Top 5 Institutional Investors
Unit Economics (Per $1K Revenue)
Economic Dimensions
Quantitative Style Profile
Style Classification
Quality Focused
Key Highlights
Company Size Small-Cap Stock | Market Capitalization 40.98M USD | Price to earnings Ratio - | 1Y Target Price 6.17 |
Price to earnings Ratio - | 1Y Target Price 6.17 | ||
Volume (30-day avg) 2.2M shares | Beta -0.14 | 52 Weeks Range 0.54 - 2.24 | Updated Date 11/08/2026 |
52 Weeks Range 0.54 - 2.24 | Updated Date 11/08/2026 | ||
Dividends yield (FY) - | Basic EPS (TTM) -0.29 |
How Company Makes Money
| Business area | What it includes | Retail investor read |
|---|---|---|
| Clinical Development | Researching and developing covalent inhibitors. | The company does not currently generate sales; it spends money to develop drugs it hopes will eventually be approved and sold. |
Valuation
Trailing PE - | Forward PE - | Enterprise Value 7.14M | Price to Sales(TTM) - |
Enterprise Value 7.14M | Price to Sales(TTM) - | ||
Enterprise Value to Revenue - | Enterprise Value to EBITDA -3.75 | Shares Outstanding 72.30M | Shares Floating 67.67M |
Shares Outstanding 72.30M | Shares Floating 67.67M | ||
Percent Insiders 7.15 | Percent Institutions 39.45 |
Financial Metrics
🧭 Investment Snapshot
Total Revenue (Scale)
Total money earned from selling products or services before any costs. It is needed to understand the scale of the business and its ability to generate income.
Net Income (Profit)
Final profit after all expenses, interest, and taxes are deducted. It is needed to determine the overall profitability available to shareholders.
Free Cash Flow (Cash Strength)
Cash remaining after operating activities and capital expenditures, showing cash available for growth. It is needed to evaluate the company’s ability to invest, pay dividends, or reduce debt.
📈 Growth & Strength
Operating Income (Core Profit)
Profit from core operations after deducting all operating expenses. It is needed to measure how efficiently the company runs its primary business activities.
EBITDA (Cash Earnings)
Earnings before interest, taxes, depreciation, and amortization, indicating operating cash potential. It is needed to compare operating performance across companies without accounting or financing differences.
Gross Profit (Unit Profitability)
Revenue minus cost of revenue, showing profit after direct production costs. It is needed to evaluate core business profitability before overhead expenses.
🛡️ Financial Safety
Cash (Liquidity Buffer)
Total cash and cash equivalents on hand. It is needed to evaluate immediate liquidity and financial flexibility.
Total Debt (Leverage Risk)
Total debt including both short-term and long-term components. It is needed to assess the company’s leverage and financial risk.
Net Working Capital (Short-Term Health)
Current assets minus current liabilities, indicating short-term liquidity strength. It is needed to assess whether the company can meet its short-term obligations.
🧱 Balance Sheet Strength
Stockholder Equity (Net Worth)
Total equity value held by shareholders. It is needed to understand the net worth of the company from the owners’ perspective.
Total Assets (Asset Base)
The full value of everything the company owns, including cash, inventory, equipment, and investments. It is needed to understand the resource base used to generate revenue.
Income Before Tax (Pre-Tax Earnings)
Income before provision for income taxes. It is needed to analyze profitability independent of tax structures.
⚙️ Cost & Drag Factors
Cost of Revenue (Production Cost)
Direct costs required to produce and deliver the products or services sold. It is needed to assess efficiency in production and service delivery.
Total Operating Expenses (Operating Cost)
Indirect costs of running the business such as salaries, marketing, and administration. It is needed to understand how much it costs to sustain ongoing business operations.
Income Tax Expense (Tax Drag)
Amount of taxes paid or payable to the government. It is needed to evaluate the impact of taxation on overall profitability.
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