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Upturn AI Summary - About
Curis Inc(CRIS)
Advisory History & Simulated Performance *
*as per simulation (see disclosures)- ALL
- 1Y
- 1M
- 1W
- BUY Advisory
- SELL Advisory (Profit)
- SELL Advisory (Loss)
- Profit
- Loss
- PASS (Skip)
Stock price based on last close Advisory Performance History (Simulated)
Upturn Advisory & Investor View for CRIS
11/06/2026: CRIS (1-star) is currently NOT-A-BUY. Pass it for now.
Curis Inc is a clinical-stage biotechnology company that funds its development of novel oncology drugs primarily through royalty income from its licensed hedgehog inhibitor, Erivedge. The company's main business strength lies in this consistent royalty stream and its focused pipeline, centered on targeted kinase inhibitors like emavusertib. The primary growth story involves the successful development and potential regulatory approval of emavusertib for blood cancers. Key risks include the high probability of clinical trial failure and the need for ongoing capital, which often results in share dilution. Curis may best suit speculative investors comfortable with high volatility and long-term research development cycles.
How to Read the Upturn Advisory
The Upturn Star Rating and the current BUY, SELL, or PASS advisory are generated by Upturn’s AI advisory engine based on proprietary signal analysis, price behavior, advisory history, and historical signal performance.
Company fundamentals, valuation, risks, and news provide supporting context about the business.
Investor Fit
| Investor style | Fit | Why |
|---|---|---|
| Growth investor | Mixed fit | The potential for growth depends on high-risk, binary outcomes in clinical trials. |
| Momentum investor | Mixed fit | The stock can exhibit momentum during clinical data readouts, but often faces volatility. |
| Value investor | Weak fit | The company lacks stable earnings or a dividend, making traditional value metrics inapplicable. |
| Dividend investor | Weak fit | Curis pays no dividends and focuses all capital on pipeline development. |
| Low-risk investor | Weak fit | Clinical-stage biotechnology carries significant downside risk and high volatility. |
Risk Profile
| Risk factor | Level | Why it matters |
|---|---|---|
| Price volatility | High | Clinical-stage biotech stocks fluctuate significantly based on regulatory and trial updates. |
| Valuation risk | Medium / high | Valuations are highly speculative, relying on the projected success of pipeline assets. |
| Competition risk (Oncology drug development) | High | The company faces immense competition from large pharma companies with superior resources. |
| Business quality | Medium | The company maintains a lean, specialized R&D team but relies on third-party commercial partners. |
| Dividend income | Low / none | The company is in a growth and development phase, not an income-generating phase. |
| Execution risk | High | Success depends entirely on the ability to successfully execute complex clinical trials. |
Price Behavior
Steep Decline
The stock price has dropped sharply with strong downward pressure.
Extreme Price Shocks
The stock has experienced exceptionally large and disruptive price movements during the period.
Analysis of Past Performance
Type Stock | Historic Profit -38.06% | Avg. Invested days 20 | Today’s Advisory PASS |
Upturn Advisory Rating  | Upturn Advisory Performance  2.0 | Stock Returns Performance  1.0 |
| Profits based on simulation | Last Close 11/06/2026 |
Upturn Scorecard
Upturn Star Rating 
Company Fundamentals
Financial Health Rating
Growth Momentum Score
Ownership
Top 5 Institutional Investors
Unit Economics (Per $1K Revenue)
Economic Dimensions
Quantitative Style Profile
Style Classification
Quality Focused
Key Highlights
Company Size Small-Cap Stock | Market Capitalization 6.05M USD | Price to earnings Ratio 0.69 | 1Y Target Price 42.67 |
Price to earnings Ratio 0.69 | 1Y Target Price 42.67 | ||
Volume (30-day avg) 8.1M shares | Beta 3.25 | 52 Weeks Range 0.33 - 28.40 | Updated Date 11/08/2026 |
52 Weeks Range 0.33 - 28.40 | Updated Date 11/08/2026 | ||
Dividends yield (FY) - | Basic EPS (TTM) 1.32 |
How Company Makes Money
| Business area | What it includes | Retail investor read |
|---|---|---|
| Royalties | Royalty revenue from sales of Erivedge by Genentech/Roche. | This is a small but steady stream of income that helps fund the company's research. |
| Clinical Development | Advancing proprietary assets like emavusertib toward potential regulatory approval. | This is a high-stakes area; success could lead to significant value, while failure results in financial loss. |
Analyzing Revenue: Products, Geography and Growth
Revenue by Products
Product revenue - Year on Year
Valuation
Trailing PE 0.69 | Forward PE - | Enterprise Value -1.89M | Price to Sales(TTM) 1.4 |
Enterprise Value -1.89M | Price to Sales(TTM) 1.4 | ||
Enterprise Value to Revenue 0.03 | Enterprise Value to EBITDA 0.56 | Shares Outstanding 6.68M | Shares Floating 2.05M |
Shares Outstanding 6.68M | Shares Floating 2.05M | ||
Percent Insiders 5.77 | Percent Institutions 10.65 |
Financial Metrics
🧭 Investment Snapshot
Total Revenue (Scale)
Total money earned from selling products or services before any costs. It is needed to understand the scale of the business and its ability to generate income.
Net Income (Profit)
Final profit after all expenses, interest, and taxes are deducted. It is needed to determine the overall profitability available to shareholders.
Free Cash Flow (Cash Strength)
Cash remaining after operating activities and capital expenditures, showing cash available for growth. It is needed to evaluate the company’s ability to invest, pay dividends, or reduce debt.
📈 Growth & Strength
Operating Income (Core Profit)
Profit from core operations after deducting all operating expenses. It is needed to measure how efficiently the company runs its primary business activities.
EBITDA (Cash Earnings)
Earnings before interest, taxes, depreciation, and amortization, indicating operating cash potential. It is needed to compare operating performance across companies without accounting or financing differences.
Gross Profit (Unit Profitability)
Revenue minus cost of revenue, showing profit after direct production costs. It is needed to evaluate core business profitability before overhead expenses.
🛡️ Financial Safety
Cash (Liquidity Buffer)
Total cash and cash equivalents on hand. It is needed to evaluate immediate liquidity and financial flexibility.
Total Debt (Leverage Risk)
Total debt including both short-term and long-term components. It is needed to assess the company’s leverage and financial risk.
Net Working Capital (Short-Term Health)
Current assets minus current liabilities, indicating short-term liquidity strength. It is needed to assess whether the company can meet its short-term obligations.
🧱 Balance Sheet Strength
Stockholder Equity (Net Worth)
Total equity value held by shareholders. It is needed to understand the net worth of the company from the owners’ perspective.
Total Assets (Asset Base)
The full value of everything the company owns, including cash, inventory, equipment, and investments. It is needed to understand the resource base used to generate revenue.
Income Before Tax (Pre-Tax Earnings)
Income before provision for income taxes. It is needed to analyze profitability independent of tax structures.
⚙️ Cost & Drag Factors
Cost of Revenue (Production Cost)
Direct costs required to produce and deliver the products or services sold. It is needed to assess efficiency in production and service delivery.
Total Operating Expenses (Operating Cost)
Indirect costs of running the business such as salaries, marketing, and administration. It is needed to understand how much it costs to sustain ongoing business operations.
Income Tax Expense (Tax Drag)
Amount of taxes paid or payable to the government. It is needed to evaluate the impact of taxation on overall profitability.
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