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Benitec Biopharma Ltd ADR (BNTC)



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Upturn Advisory Summary
09/16/2025: BNTC (1-star) has a low Upturn Star Rating. Not recommended to BUY.
1 Year Target Price $25.71
1 Year Target Price $25.71
4 | Strong Buy |
3 | Buy |
0 | Hold |
0 | Sell |
0 | Strong Sell |
Analysis of Past Performance
Type Stock | Historic Profit -6.75% | Avg. Invested days 26 | Today’s Advisory Consider higher Upturn Star rating |
Upturn Star Rating ![]() ![]() | Upturn Advisory Performance ![]() | Stock Returns Performance ![]() |
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Key Highlights
Company Size Small-Cap Stock | Market Capitalization 359.63M USD | Price to earnings Ratio - | 1Y Target Price 25.71 |
Price to earnings Ratio - | 1Y Target Price 25.71 | ||
Volume (30-day avg) 7 | Beta 0.43 | 52 Weeks Range 8.20 - 17.15 | Updated Date 09/16/2025 |
52 Weeks Range 8.20 - 17.15 | Updated Date 09/16/2025 | ||
Dividends yield (FY) - | Basic EPS (TTM) -5.03 |
Analyzing Revenue: Products, Geography and Growth
Revenue by Products
Product revenue - Year on Year
Revenue by Geography
Geography revenue - Year on Year
Earnings Date
Report Date - | When - | Estimate - | Actual - |
Profitability
Profit Margin - | Operating Margin (TTM) - |
Management Effectiveness
Return on Assets (TTM) -31.34% | Return on Equity (TTM) -48.57% |
Valuation
Trailing PE - | Forward PE - | Enterprise Value 260944995 | Price to Sales(TTM) 2770.13 |
Enterprise Value 260944995 | Price to Sales(TTM) 2770.13 | ||
Enterprise Value to Revenue 10457.68 | Enterprise Value to EBITDA 0.27 | Shares Outstanding 26250500 | Shares Floating 12567143 |
Shares Outstanding 26250500 | Shares Floating 12567143 | ||
Percent Insiders 3.12 | Percent Institutions 90.69 |
Upturn AI SWOT
Benitec Biopharma Ltd ADR

Company Overview
History and Background
Benitec Biopharma Limited is a biotechnology company specializing in the development of gene silencing therapeutics based on RNA interference (RNAi). Founded in 1997, it has focused on developing novel treatments for diseases with unmet medical needs, primarily in ophthalmology and liver diseases. Originally based in Australia, the company has evolved through various partnerships and strategic shifts.
Core Business Areas
- Ophthalmology: Development of gene silencing therapeutics for ocular diseases, focusing on conditions like Oculopharyngeal Muscular Dystrophy (OPMD).
- Liver Diseases: Research and development of treatments for liver diseases, leveraging their RNAi platform.
Leadership and Structure
Information about the leadership team and organizational structure is not readily available. The current structure likely includes a CEO, CFO, and heads of research and development, as well as a board of directors.
Top Products and Market Share
Key Offerings
- BB-301 (for OPMD): BB-301 is an adeno-associated virus (AAV) based gene therapy designed to treat OPMD. The competitors include companies working on gene therapies for neuromuscular disorders, such as Sarepta Therapeutics. Market share data not available due to development stage.
Market Dynamics
Industry Overview
The gene therapy market is experiencing rapid growth, driven by advancements in technology and increasing regulatory approvals. The industry is competitive, with many companies developing novel therapies for a range of diseases.
Positioning
Benitec Biopharma is positioned as a specialized gene therapy company focusing on specific diseases. Their competitive advantage lies in their RNAi technology and focus on unmet medical needs.
Total Addressable Market (TAM)
The TAM for gene therapies targeting specific diseases like OPMD is estimated to be in the hundreds of millions of dollars. Benitec's position depends on the success of BB-301 and its ability to capture a significant share of the OPMD market if approved.
Upturn SWOT Analysis
Strengths
- Proprietary RNAi technology
- Focus on unmet medical needs
- Potential for breakthrough therapies
Weaknesses
- Limited financial resources
- Reliance on a small number of pipeline products
- High regulatory risk
Opportunities
- Partnerships with larger pharmaceutical companies
- Expansion into new disease areas
- Advancements in gene therapy technology
Threats
- Competition from other gene therapy companies
- Regulatory hurdles
- Clinical trial failures
- Patent challenges
Competitors and Market Share
Key Competitors
- SRPT
- BMY
- VRTX
Competitive Landscape
Benitec Biopharma faces intense competition from larger pharmaceutical companies with greater resources and established market presence. Its success depends on demonstrating the efficacy and safety of its gene therapy products.
Growth Trajectory and Initiatives
Historical Growth: Historical growth has been limited due to the company's stage of development, primarily focused on research and clinical trials.
Future Projections: Future growth projections are highly dependent on the success of BB-301 and other pipeline products.
Recent Initiatives: Recent initiatives likely include advancing BB-301 through clinical trials and exploring potential partnerships.
Summary
Benitec Biopharma is a clinical-stage biotechnology company with promising gene silencing technology. They focus on diseases with limited treatment options. The company's future hinges on the success of its lead product, BB-301, and its ability to secure funding. Competition is high, and regulatory risks are substantial, requiring Benitec to achieve clear clinical milestones.
Peer Comparison
Sources and Disclaimers
Data Sources:
- Company Website
- SEC Filings
- Third-party Market Research Reports
Disclaimers:
The information provided is for informational purposes only and does not constitute investment advice. Investment decisions should be based on individual research and due diligence. Market share estimates are based on available data and may not be precise.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About Benitec Biopharma Ltd ADR
Exchange NASDAQ | Headquaters Hayward, CA, United States | ||
IPO Launch date 2015-08-18 | Executive Chairman & CEO Dr. Jerel A. Banks M.D., Ph.D. | ||
Sector Healthcare | Industry Biotechnology | Full time employees 16 | Website https://benitec.com |
Full time employees 16 | Website https://benitec.com |
Benitec Biopharma Inc., a clinical-stage biotechnology company, focuses on the development of novel genetic medicines. The company develops DNA-directed RNA interference-based therapeutics for chronic and life-threatening human conditions. It is developing BB-301, an adeno-associated virus based gene therapy agent for treating oculopharyngeal muscular dystrophy. Benitec Biopharma Inc. was incorporated in 1995 and is headquartered in Hayward, California.

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