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Crispr Therapeutics AG (CRSP)

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Upturn Advisory Summary
12/12/2025: CRSP (1-star) is currently NOT-A-BUY. Pass it for now.
1 Year Target Price $81.33
1 Year Target Price $81.33
| 12 | Strong Buy |
| 5 | Buy |
| 10 | Hold |
| 0 | Sell |
| 1 | Strong Sell |
Analysis of Past Performance
Type Stock | Historic Profit 16.52% | Avg. Invested days 24 | Today’s Advisory PASS |
Upturn Star Rating ![]() | Upturn Advisory Performance | Stock Returns Performance |
Key Highlights
Company Size Mid-Cap Stock | Market Capitalization 5.40B USD | Price to earnings Ratio - | 1Y Target Price 81.33 |
Price to earnings Ratio - | 1Y Target Price 81.33 | ||
Volume (30-day avg) 28 | Beta 1.73 | 52 Weeks Range 30.04 - 78.48 | Updated Date 12/13/2025 |
52 Weeks Range 30.04 - 78.48 | Updated Date 12/13/2025 | ||
Dividends yield (FY) - | Basic EPS (TTM) -5.54 |
Analyzing Revenue: Products, Geography and Growth
Revenue by Products
Product revenue - Year on Year
Earnings Date
Report Date - | When - | Estimate - | Actual - |
Profitability
Profit Margin - | Operating Margin (TTM) -14854.78% |
Management Effectiveness
Return on Assets (TTM) -13.28% | Return on Equity (TTM) -25.33% |
Valuation
Trailing PE - | Forward PE 23.36 | Enterprise Value 3831304534 | Price to Sales(TTM) 140.9 |
Enterprise Value 3831304534 | Price to Sales(TTM) 140.9 | ||
Enterprise Value to Revenue 109.47 | Enterprise Value to EBITDA 14.16 | Shares Outstanding 95300233 | Shares Floating 94801813 |
Shares Outstanding 95300233 | Shares Floating 94801813 | ||
Percent Insiders 1.61 | Percent Institutions 77.94 |
About Crispr Therapeutics AG
Exchange NASDAQ | Headquaters - | ||
IPO Launch date 2016-10-19 | CEO & Chairman Dr. Samarth Kulkarni Ph.D. | ||
Sector Healthcare | Industry Biotechnology | Full time employees 393 | Website https://www.crisprtx.com |
Full time employees 393 | Website https://www.crisprtx.com | ||
CRISPR Therapeutics AG, a gene editing company, focuses on developing gene-based medicines for serious human diseases using its Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/CRISPR-associated protein 9 (Cas9) platform. The company's CRISPR/Cas9 is a revolutionary technology for gene editing which is the process of precisely altering specific sequences of genomic DNA. It has a portfolio of therapeutic programs across a range of disease areas, including hemoglobinopathies, CAR T cell therapies, in vivo, and type 1 diabetes, as well as develops investigational CAR T programs, including an autologous, gene-edited CAR T program targeting glypican-3 (GPC3) for the potential treatment of solid tumors. The company's lead product candidate is CASGEVY, an ex vivo CRISPR/Cas9 gene-edited cell therapy for treating patients suffering from transfusion-dependent beta-thalassemia, severe sickle cell disease (SCD), and hemoglobinopathies in which a patient's hematopoietic stem and progenitor cells are edited to produce high levels of fetal hemoglobin in red blood cells. It also develops CAR T cell therapies, including CTX112 targeting cluster of differentiation 19 (CD19) and CTX131 targeting CD70 for oncology and autoimmune indications; CTX310 and CTX320, in vivo gene editing to address the cardiovascular disease by disrupting the validated targets angiopoietin-like protein 3 and lipoprotein; and CTX211, an allogeneic, gene-edited, hypoimmune stem cell-derived product candidate for the treatment of T1D. It has strategic partnerships with Vertex Pharmaceuticals Incorporated, Nkarta, Inc., and Capsida Biotherapeutics. CRISPR Therapeutics AG was incorporated in 2013 and is headquartered in Zug, Switzerland.

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