BioNTech SE logo

BioNTech SE(BNTX)

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ADVISORIES YOU CAN VERIFY
QUALITY SIGNAL
1-STAR RATING
PASS
LAST CLOSE
$98.52
09/25/2026
(24-hour delay)

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*as per simulation (see disclosures)
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Upturn Advisory & Investor View for BNTX

09/25/2026: BNTX (1-star) is currently NOT-A-BUY. Pass it for now.

BioNTech SE is a biotechnology company focused on developing personalized immunotherapies, most notably through its validated mRNA platform. While the company achieved historic financial success due to the global rollout of its COVID-19 vaccine, it is currently in a transition phase. The primary investment story rests on its pipeline of oncology candidates, which could unlock significant future value. However, investors face high execution and clinical trial risks, alongside intense competition from both large pharmaceutical firms and biotech peers. The stock is best suited for growth-oriented investors with a high risk tolerance who are monitoring clinical trial data as the key driver of long-term development.

How to Read the Upturn Advisory

The Upturn Star Rating and the current BUY, SELL, or PASS advisory are generated by Upturn’s AI advisory engine based on proprietary signal analysis, price behavior, advisory history, and historical signal performance.

Company fundamentals, valuation, risks, and news provide supporting context about the business.

Investor Fit

Investor styleFitWhy
Growth investorStrong fitThe company offers high-growth potential linked to its mRNA pipeline and innovation.
Momentum investorMixed fitMomentum depends heavily on clinical trial news and is conditional on positive market signals.
Value investorWeak fitThe company's valuation is tied to future pipeline potential rather than current earnings.
Dividend investorWeak fitBioNTech does not pay dividends, as it focuses entirely on reinvestment.
Low-risk investorWeak fitBiotech stocks are inherently volatile due to clinical and regulatory uncertainties.

Risk Profile

Risk factorLevelWhy it matters
Price volatilityHighThe stock is highly sensitive to news regarding clinical trials and pandemic-era revenue trends.
Valuation riskMedium / highCurrent valuations are speculative, relying on the future success of cancer therapies.
Competition risk (mRNA and Oncology)HighLarge-cap firms and peers like Moderna pose significant competitive threats to pipeline development.
Business qualityMediumWhile the platform technology is strong, the transition from a single-product success is ongoing.
Dividend incomeLow / noneInvestors should not expect income as capital is reserved for operations.
Execution riskHighTranslating promising early data into approved oncology products is historically difficult.

Price Behavior

Downtrend
PRICE PATH

Downtrend

The stock has experienced a sustained decline in price over recent periods.

Choppy
PRICE STABILITY

Choppy

The stock has experienced frequent reversals and pronounced short-term price swings.

Analysis of Past Performance

Type Stock
Historic Profit -41.33%
Avg. Invested days 28
Today’s Advisory PASS
Upturn Advisory Rating upturn star rating icon
Upturn Advisory Performance Upturn Advisory Performance icon 1.0
Stock Returns Performance Upturn Returns Performance icon 1.0
Upturn Profits based on simulation icon Profits based on simulation
Upturn last close icon Last Close 09/25/2026

Upturn Scorecard

Upturn Star Rating

★★★★★
BNTX receives a 3-star rating, supported by solid analyst coverage. The rating is constrained by soft unit economics, and weak price momentum.

Company Fundamentals

★★★★★
BNTX has moderate overall fundamentals (3 stars), with moderate financial health, moderate growth momentum, and solid ownership. In FY2025 versus FY2024, solid cash generation (FCF margin 9.8%) is partially offset by negative earnings growth (-64.0%), moderate revenue growth (+0.2%), soft profitability (net margin -39.6%).

Financial Health Rating

★★★★★
BNTX's financial health is supported by solid liquidity, including working-capital and asset support (WC/assets 63.7%). Profitability is soft (2 stars), which helps explain the 3-star overall score.

Growth Momentum Score

★★★★★
Free-cash-flow growth is BNTX's strongest growth driver at +210.3% FY2025 versus FY2024 (strong, 5 stars). By comparison, while revenue growth (+0.2%, moderate) and earnings growth (-64.0%, negative) hold the profile back, so recent growth is not broad-based across the business.

Ownership

★★★★★
Institutional ownership is 20.4% and approximately 43.3% of outstanding shares are publicly tradable, supporting liquidity and institutional participation. Insider ownership of 57.36% supports management-shareholder alignment.

Top 5 Institutional Investors

T. Rowe Price Investment Management,Inc. 2.33%
FMR Inc 2.27%
PRIMECAP Management Company 1.50%
Dodge & Cox 1.46%
Flossbach von Storch AG 0.89%

Unit Economics (Per $1K Revenue)

★★★★★
BNTX generates approximately $776 of gross profit, $-226 of operating income, and $98 of free cash flow for every $1,000 of revenue. Based on FY2025 results. Strong cash conversion and healthy margins support the rating, although capital efficiency remains below the highest tier.

Economic Dimensions

★★★★★
Effective Tax Rate: -8.12% (Tax Credit)

Quantitative Style Profile

★★★★★
BNTX has a large-cap profile. Weak momentum is the primary drawback, while valuation that is moderately attractive rather than deeply discounted.

Style Classification

Quality Focused

High VolatilityLarge / Mega Cap Stability

Key Highlights

Company Size Large-Cap Stock
Market Capitalization 24.93B USD
Price to earnings Ratio -
1Y Target Price 117.24
Price to earnings Ratio -
1Y Target Price 117.24
Volume (30-day avg) 1.4M shares
Beta 1.29
52 Weeks Range 79.52 - 124.00
Updated Date 09/25/2026
52 Weeks Range 79.52 - 124.00
Updated Date 09/25/2026
Dividends yield (FY) -
Basic EPS (TTM) -7.75

How Company Makes Money

Business areaWhat it includesRetail investor read
COVID-19 Vaccine (Comirnaty)Global sales and royalties from the mRNA vaccine.The main historical revenue source, currently experiencing lower demand.
Collaborations and R&DUpfront and milestone payments from pharma partners.Revenue from partners who license or co-develop BioNTech's technology.

Analyzing Revenue: Products, Geography and Growth

Revenue by Products

Product revenue - Year on Year

Revenue by Geography

Geography revenue - Year on Year

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Valuation

Trailing PE -
Forward PE 7.04
Enterprise Value 8.18B
Price to Sales(TTM) 9.41
Enterprise Value 8.18B
Price to Sales(TTM) 9.41
Enterprise Value to Revenue 2.7
Enterprise Value to EBITDA 110.81
Shares Outstanding 251.20M
Shares Floating 108.79M
Shares Outstanding 251.20M
Shares Floating 108.79M
Percent Insiders 57.36
Percent Institutions 20.43

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Financial Metrics

🧭 Investment Snapshot

Total Revenue (Scale)

Information icon Total money earned from selling products or services before any costs. It is needed to understand the scale of the business and its ability to generate income.

Net Income (Profit)

Information icon Final profit after all expenses, interest, and taxes are deducted. It is needed to determine the overall profitability available to shareholders.

Free Cash Flow (Cash Strength)

Information icon Cash remaining after operating activities and capital expenditures, showing cash available for growth. It is needed to evaluate the company’s ability to invest, pay dividends, or reduce debt.

📈 Growth & Strength

Operating Income (Core Profit)

Information icon Profit from core operations after deducting all operating expenses. It is needed to measure how efficiently the company runs its primary business activities.

EBITDA (Cash Earnings)

Information icon Earnings before interest, taxes, depreciation, and amortization, indicating operating cash potential. It is needed to compare operating performance across companies without accounting or financing differences.

Gross Profit (Unit Profitability)

Information icon Revenue minus cost of revenue, showing profit after direct production costs. It is needed to evaluate core business profitability before overhead expenses.

🛡️ Financial Safety

Cash (Liquidity Buffer)

Information icon Total cash and cash equivalents on hand. It is needed to evaluate immediate liquidity and financial flexibility.

Total Debt (Leverage Risk)

Information icon Total debt including both short-term and long-term components. It is needed to assess the company’s leverage and financial risk.

Net Working Capital (Short-Term Health)

Information icon Current assets minus current liabilities, indicating short-term liquidity strength. It is needed to assess whether the company can meet its short-term obligations.

🧱 Balance Sheet Strength

Stockholder Equity (Net Worth)

Information icon Total equity value held by shareholders. It is needed to understand the net worth of the company from the owners’ perspective.

Total Assets (Asset Base)

Information icon The full value of everything the company owns, including cash, inventory, equipment, and investments. It is needed to understand the resource base used to generate revenue.

Income Before Tax (Pre-Tax Earnings)

Information icon Income before provision for income taxes. It is needed to analyze profitability independent of tax structures.

⚙️ Cost & Drag Factors

Cost of Revenue (Production Cost)

Information icon Direct costs required to produce and deliver the products or services sold. It is needed to assess efficiency in production and service delivery.

Total Operating Expenses (Operating Cost)

Information icon Indirect costs of running the business such as salaries, marketing, and administration. It is needed to understand how much it costs to sustain ongoing business operations.

Income Tax Expense (Tax Drag)

Information icon Amount of taxes paid or payable to the government. It is needed to evaluate the impact of taxation on overall profitability.

About BioNTech SE

Exchange NASDAQ
Headquarters -
IPO Launch date 2019-10-10
Co-Founder, CEO & Chair of the Management Board Dr. Ugur Sahin M.D.
Sector Healthcare
Industry Biotechnology
Full time employees 7807
Full time employees 7807

BioNTech SE, together with its subsidiaries, engages in the development and commercialization of immunotherapies in Germany. The company offers BNT162, an mRNA vaccine for the treatment of SARS-CoV-2 virus. It also develops oncology drugs under Phase III clinical trial, including Gotistobart for metastatic non-small cell lung cancer, Pumitamig for small cell lung cancer and advanced/metastatic triple-negative breast cancer, and Trastuzumab pamirtecan for metastatic breast cancer and epirubicin and cyclophosphamide; and drugs under Phase 2/3 clinical trial, such as BNT113 for human papillomavirus and head and neck squamous cell carcinoma, as well as Pumitamig for metastatic colorectal and non-small cell lung cancer. In addition, the company engages in the development of oncology drugs under Phase II clinical trial comprising BNT116 for advance non-small cell lung cancer, BNT326/YL202 for multiple solid tumors and advanced/metastatic breast cancer, Autogene cevumeran for advance colorectal cancer, and Gotistobart for platinum-resistant ovarian cancer, as well as Pumitamig for glioblastoma, hepatocellular carcinoma, malignant pleural mesothelioma, neuroendocrine neoplasms, and metastatic pancreatic ductal adenocarcinoma. Further, it develops BNT166 which is Phase II clinical trial for mpox virus; and infectious diseases drugs under Phase 1/2 clinical trial, which include BNT162 + BNT161 for SARS-CoV-2 and influenza, BNT164 for tuberculosis, BNT165 for malaria, and BNT166 for mpox. The company was incorporated in 2008 and is headquartered in Mainz, Germany.