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BioNTech SE (BNTX)

Upturn stock ratingUpturn stock rating
$98.15
Last Close (24-hour delay)
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PASS
  • BUY Advisory
  • SELL Advisory (Profit)​
  • SELL Advisory (Loss)​
  • Profit
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Upturn Stock infoUpturn Stock info Stock price based on last close
*as per simulation
(see disclosures)
Time period over
  • ALL
  • YEAR
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Upturn Advisory Summary

09/17/2025: BNTX (1-star) is currently NOT-A-BUY. Pass it for now.

Upturn Star Rating

rating

Not Recommended Performance

These Stocks/ETFs, based on Upturn Advisory, consistently fall short of market performance, signaling caution before investing.

Number of Analysts

rating

21 Analysts rated it

Well-followed company, solid analyst reports, reliable data for confident investing.

1 Year Target Price $137.62

1 Year Target Price $137.62

Analysts Price Target For last 52 week
$137.62 Target price
52w Low $81.2
Current$98.15
52w High $129.27

Analysis of Past Performance

Type Stock
Historic Profit -19.93%
Avg. Invested days 34
Today’s Advisory PASS
Upturn Star Rating Upturn stock ratingUpturn stock rating
Upturn Advisory Performance Upturn Advisory Performance 1.0
Stock Returns Performance Upturn Returns Performance 1.0
Upturn Profits based on simulationUpturn Profits based on simulation Profits based on simulation
Upturn Profits based on simulationUpturn Profits based on simulation Last Close 09/17/2025

Key Highlights

Company Size Large-Cap Stock
Market Capitalization 23.86B USD
Price to earnings Ratio -
1Y Target Price 137.62
Price to earnings Ratio -
1Y Target Price 137.62
Volume (30-day avg) 21
Beta 1.4
52 Weeks Range 81.20 - 129.27
Updated Date 09/17/2025
52 Weeks Range 81.20 - 129.27
Updated Date 09/17/2025
Dividends yield (FY) -
Basic EPS (TTM) -1.68

Analyzing Revenue: Products, Geography and Growth

Revenue by Products

Product revenue - Year on Year

Revenue by Geography

Geography revenue - Year on Year

Earnings Date

Report Date -
When -
Estimate -
Actual -

Profitability

Profit Margin -11.98%
Operating Margin (TTM) -167.45%

Management Effectiveness

Return on Assets (TTM) -2.14%
Return on Equity (TTM) -1.84%

Valuation

Trailing PE -
Forward PE 7.04
Enterprise Value 7388028584
Price to Sales(TTM) 8.29
Enterprise Value 7388028584
Price to Sales(TTM) 8.29
Enterprise Value to Revenue 2.19
Enterprise Value to EBITDA 110.81
Shares Outstanding 240399008
Shares Floating 93813198
Shares Outstanding 240399008
Shares Floating 93813198
Percent Insiders 62.69
Percent Institutions 23.12

ai summary icon Upturn AI SWOT

BioNTech SE

stock logo

Company Overview

overview logo History and Background

BioNTech SE was founded in 2008 in Mainz, Germany, by Uu011fur u015eahin and u00d6zlem Tu00fcreci. Initially focused on cancer immunotherapy, it gained prominence through its rapid development of the COVID-19 vaccine with Pfizer, marking a pivotal moment in its history.

business area logo Core Business Areas

  • Human Therapeutics: Development of mRNA-based therapies for cancer and infectious diseases.
  • mRNA Manufacturing: Production of mRNA for clinical trials and commercial use.
  • Early Discovery Programs: Research into novel targets and technologies for immunotherapy.

leadership logo Leadership and Structure

The company is led by CEO Uu011fur u015eahin. The organizational structure includes research, development, and commercial operations, with a focus on mRNA technology.

Top Products and Market Share

overview logo Key Offerings

  • Comirnaty (COVID-19 Vaccine): An mRNA-based vaccine developed in partnership with Pfizer. Revenue from the vaccine constituted the bulk of the company's revenue in 2021 and 2022. Competitors include Moderna (MRNA), Novavax (NVAX), and other traditional vaccine manufacturers.

Market Dynamics

industry overview logo Industry Overview

The biotechnology industry is highly competitive and rapidly evolving, with a strong focus on innovation in areas like mRNA therapeutics and personalized medicine.

Positioning

BioNTech SE is a leader in mRNA technology, particularly in vaccine development, holding a strong position in the infectious disease market and expanding into oncology. Its partnership with Pfizer is a significant competitive advantage.

Total Addressable Market (TAM)

The global mRNA therapeutics and vaccines market is expected to reach billions of dollars. BioNTech SE is well positioned to capture a significant share of this TAM, focusing on both infectious diseases and oncology.

Upturn SWOT Analysis

Strengths

  • Leading mRNA Technology
  • Successful COVID-19 Vaccine
  • Strategic Partnership with Pfizer
  • Strong Cash Position
  • Innovative R&D Pipeline

Weaknesses

  • Reliance on COVID-19 Vaccine Revenue
  • Limited Commercial Track Record Beyond Vaccine
  • Dependence on Pfizer for Distribution
  • High R&D Costs
  • Regulatory Risks

Opportunities

  • Expansion into Oncology
  • Development of New mRNA Therapies
  • Geographic Expansion
  • Strategic Acquisitions
  • Partnerships with Other Biopharma Companies

Threats

  • Competition from Other Vaccine Manufacturers
  • Decreasing COVID-19 Vaccine Demand
  • Clinical Trial Failures
  • Patent Disputes
  • Changes in Regulatory Landscape

Competitors and Market Share

competitor logo Key Competitors

  • MRNA
  • LLY
  • GILD
  • NVAX

Competitive Landscape

BioNTech SE has a strong position in mRNA technology but faces intense competition. MRNA is close rival in COVID-19 vaccine and mRNA therapy. Companies such as LLY and GILD have many more offerings and cover a wider market.

Major Acquisitions

Pharma Lever Name

  • Year: 2023
  • Acquisition Price (USD millions): 70
  • Strategic Rationale: Expand pipeline of innovative therapeutic candidates.

Growth Trajectory and Initiatives

Historical Growth: Rapid growth in 2021 and 2022 driven by vaccine sales, followed by normalization in 2023.

Future Projections: Future growth depends on expanding the pipeline beyond the COVID-19 vaccine and successfully developing mRNA therapies for cancer and other diseases.

Recent Initiatives: Focus on oncology pipeline expansion, collaborations with other biotech firms, and investments in new technologies.

Summary

BioNTech SE leveraged its mRNA technology to become a key player in the COVID-19 vaccine market. While the company's revenue surged in 2021 and 2022, it now faces the challenge of diversifying its pipeline and reducing reliance on COVID-19 vaccine revenue. Its future success hinges on its ability to develop new mRNA therapies, particularly in oncology. The company must also navigate a competitive landscape and address regulatory risks.

Peer Comparison

Sources and Disclaimers

Data Sources:

  • Company Filings
  • Analyst Reports
  • Industry News
  • Financial Databases

Disclaimers:

This analysis is based on publicly available information and is for informational purposes only. It is not financial advice. Market share data is approximate.

Upturn AI SummarizationUpturn AI Summarization AI Summarization is directionally correct and might not be accurate.

Upturn AI SummarizationUpturn AI Summarization Summarized information shown could be a few years old and not current.

Upturn AI SummarizationUpturn AI Summarization Fundamental Rating based on AI could be based on old data.

Upturn AI SummarizationUpturn AI Summarization AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.

About BioNTech SE

Exchange NASDAQ
Headquaters -
IPO Launch date 2019-10-10
Co-Founder, CEO & Chair of the Management Board Dr. Ugur Sahin M.D.
Sector Healthcare
Industry Biotechnology
Full time employees 6772
Full time employees 6772

BioNTech SE, a biotechnology company, develops and commercializes immunotherapies to treat cancer and infectious diseases in Germany. The company develops BNT111, which is in Phase 2 clinical trial for advance melanoma; BNT113, which is in Phase 2 clinical trial to treat head and neck squamous cell carcinoma; BNT116, which is in Phase I clinical trial for non-small cell lung cancer; BNT142, which is in phase 1/2 clinical trial for multiple solid tumors; BNT151, which is in phase 1/2 clinical trial for solid tumors; BNT152+BNT153, which is in phase 1 clinical trial for solid tumors; and BNT122/RO7198457, which is in Phase 2 clinical trial to treat adjuvant high-risk muscle-invasive urothelial carcinoma, colorectal cancer, pancreatic ductal adenocarcinoma, advance melanoma, as well as in phase 1a/1b clinical trial for advanced/metastatic solid tumors. It also develops BNT211, which is in phase 1 clinical trial to treat CLDN6+ solid tumors; BNT221, phase 1 clinical trial for the treatment of cancer; BNT311/GEN1046 (acasunlimab), which is in phase 3 clinical trial for solid tumors; BNT312/GEN1042, which is in phase 1/2 and 1 clinical trial to treat solid tumors; BNT314/GEN1059, which is in Phase 1/2 clinical trial for advanced or metastatic solid tumors; BNT315/GEN1055, which is in phase 1/2 clinical trial for advanced solid tumors; BNT317, which is in phase 1 clinical trial for advanced solid tumors; BNT327, which is in phase 1/2, 2, and 3 clinical trial to treat small cell lung cancer, advanced/metastatic tnbc, neuroendocrine neoplasm, malignant mesothelioma, EGFR-mutant non-squamous, hepatocellular carcinoma, and advanced solid tumors; and BNT316/ONC-392, which is in phase 1/2, 2, and 3 clinical trial to treat metastatic, non-small cell lung cancer, platinum-resistant ovarian cancer, metastatic castration resistant prostate cancer, and advanced or metastatic solid tumor. BioNTech SE was incorporated in 2008 and is headquartered in Mainz, Germany.