Cabaletta Bio Inc logo

Cabaletta Bio Inc(CABA)

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ADVISORIES YOU CAN VERIFY
QUALITY SIGNAL
1-STAR RATING
PASS
LAST CLOSE
$2.15
09/24/2026
(24-hour delay)

Advisory History & Simulated Performance *

*as per simulation (see disclosures)
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Upturn Advisory & Investor View for CABA

09/24/2026: CABA (1-star) is currently NOT-A-BUY. Pass it for now.

Cabaletta Bio is a clinical-stage biotechnology company developing engineered T cell therapies intended to address B cell-mediated autoimmune diseases. Its primary value proposition lies in the potential of its CABA platform to provide targeted, potentially curative treatments for complex conditions. While the company has a promising pipeline, most notably CABA-201, it remains a pre-revenue entity facing high financial and clinical execution risks. Investors should monitor clinical data readouts and the company's ability to maintain its cash runway through future development milestones. This stock is best suited for growth-oriented investors with a high tolerance for the volatility typical of clinical-stage biotechnology equities.

How to Read the Upturn Advisory

The Upturn Star Rating and the current BUY, SELL, or PASS advisory are generated by Upturn’s AI advisory engine based on proprietary signal analysis, price behavior, advisory history, and historical signal performance.

Company fundamentals, valuation, risks, and news provide supporting context about the business.

Investor Fit

Investor styleFitWhy
Growth investorMixed fitThe company offers high-growth potential via clinical development, but carries the inherent risks of a pre-revenue biotech firm.
Momentum investorStrong fit while signal remains positiveMomentum investors may find the stock attractive during positive clinical data news cycles or potential partnership announcements.
Value investorWeak fitThe company lacks earnings, cash flow, or a long-term revenue base, making it unsuitable for traditional value-based strategies.
Dividend investorWeak fitCabaletta Bio is a clinical-stage biotech and does not pay dividends.
Low-risk investorWeak fitThe high volatility and binary nature of clinical biotech risks make this unsuitable for low-risk portfolios.

Risk Profile

Risk factorLevelWhy it matters
Price volatilityHighThe stock is susceptible to significant price swings based on clinical trial updates and biotech market sentiment.
Valuation riskHighValuation is highly speculative, relying on future probabilities of regulatory success rather than current earnings.
Competition risk (Large Pharma/Biotech)Medium / highLarge competitors with more resources could develop superior therapies or gain market share more effectively.
Business qualityMediumWhile the platform technology is innovative, the lack of commercialized products limits the quality assessment to clinical potential.
Dividend incomeLow / noneThe company reinvests all capital into R&D and provides no income.
Execution riskHighThe company must successfully navigate complex clinical trials and regulatory approval processes to survive and grow.

Price Behavior

Rolling Over
PRICE PATH

Rolling Over

The price momentum is slowing down and beginning to turn downward.

Extreme Price Shocks
PRICE STABILITY

Extreme Price Shocks

The stock has experienced exceptionally large and disruptive price movements during the period.

Analysis of Past Performance

Type Stock
Historic Profit -82.36%
Avg. Invested days 16
Today’s Advisory PASS
Upturn Advisory Rating upturn star rating icon
Upturn Advisory Performance Upturn Advisory Performance icon 1.0
Stock Returns Performance Upturn Returns Performance icon 1.0
Upturn Profits based on simulation icon Profits based on simulation
Upturn last close icon Last Close 09/24/2026

Upturn Scorecard

Upturn Star Rating

★★★★★
CABA receives a 2-star rating, supported by solid analyst coverage. The rating is constrained by weak unit economics, soft quantitative characteristics, and weak price momentum.

Company Fundamentals

★★★★★
CABA has moderate overall fundamentals (3 stars), with moderate financial health, soft growth momentum, and solid ownership. In FY2025 versus FY2024, growth and ownership metrics are mixed: negative earnings growth (-44.9%), soft cash generation (FCF margin 0.0%), slightly negative revenue growth (+0.0%).

Financial Health Rating

★★★★★
CABA's financial health is supported by strong efficiency, including operating-expense and cost-of-revenue discipline (opex 0.0% of revenue). Profitability is weak (1 stars), which helps explain the 3-star overall score.

Growth Momentum Score

★★★★★
CABA's growth profile is soft, with the least-weak measure being revenue growth at +0.0% FY2025 versus FY2024. By comparison, while earnings growth (-44.9%, negative) and free-cash-flow growth (-46.3%, negative) hold the profile back, so recent growth is not broad-based across the business.

Ownership

★★★★★
Institutional ownership is 94.1% and approximately 83.4% of outstanding shares are publicly tradable, supporting liquidity and institutional participation. Insider ownership is only 0.97%, which materially reduces the ownership score.

Top 5 Institutional Investors

Jennison Associates LLC 11.82%
T. Rowe Price Investment Management,Inc. 6.54%
Bain Capital Life Sciences Investors, LLC 5.71%
Adage Capital Partners Gp LLC 5.41%
Cormorant Asset Management, LLC 3.24%

Unit Economics (Per $1K Revenue)

★★★★★
CABA generates approximately $-0 of gross profit, $-0 of operating income, and $-0 of free cash flow for every $1,000 of revenue. Based on FY2025 results. Strong cash conversion and healthy margins support the rating, although capital efficiency remains below the highest tier.

Economic Dimensions

★★★★★
Effective Tax Rate: 0.00%

Quantitative Style Profile

★★★★★
CABA has a liquid profile. Weak momentum is the primary drawback, while elevated volatility.

Style Classification

Quality Focused

High VolatilitySmall / Mid Cap RiskShort Squeeze RiskHighly Liquid / Institution-Friendly

Key Highlights

Company Size Small-Cap Stock
Market Capitalization 376.39M USD
Price to earnings Ratio -
1Y Target Price 13.25
Price to earnings Ratio -
1Y Target Price 13.25
Volume (30-day avg) 5.7M shares
Beta 3.26
52 Weeks Range 2.00 - 4.23
Updated Date 09/24/2026
52 Weeks Range 2.00 - 4.23
Updated Date 09/24/2026
Dividends yield (FY) -
Basic EPS (TTM) -1.22

How Company Makes Money

Business areaWhat it includesRetail investor read
Clinical Development / R&DThe business relies on capital raises to fund research for CABA-201 and other pipeline assets.The company is currently not generating revenue and relies on selling stock to fund its research projects.
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Valuation

Trailing PE -
Forward PE -
Enterprise Value 223.63M
Price to Sales(TTM) -
Enterprise Value 223.63M
Price to Sales(TTM) -
Enterprise Value to Revenue -
Enterprise Value to EBITDA -3.44
Shares Outstanding 169.55M
Shares Floating 141.48M
Shares Outstanding 169.55M
Shares Floating 141.48M
Percent Insiders 0.97
Percent Institutions 94.08

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Financial Metrics

🧭 Investment Snapshot

Total Revenue (Scale)

Information icon Total money earned from selling products or services before any costs. It is needed to understand the scale of the business and its ability to generate income.

Net Income (Profit)

Information icon Final profit after all expenses, interest, and taxes are deducted. It is needed to determine the overall profitability available to shareholders.

Free Cash Flow (Cash Strength)

Information icon Cash remaining after operating activities and capital expenditures, showing cash available for growth. It is needed to evaluate the company’s ability to invest, pay dividends, or reduce debt.

📈 Growth & Strength

Operating Income (Core Profit)

Information icon Profit from core operations after deducting all operating expenses. It is needed to measure how efficiently the company runs its primary business activities.

EBITDA (Cash Earnings)

Information icon Earnings before interest, taxes, depreciation, and amortization, indicating operating cash potential. It is needed to compare operating performance across companies without accounting or financing differences.

Gross Profit (Unit Profitability)

Information icon Revenue minus cost of revenue, showing profit after direct production costs. It is needed to evaluate core business profitability before overhead expenses.

🛡️ Financial Safety

Cash (Liquidity Buffer)

Information icon Total cash and cash equivalents on hand. It is needed to evaluate immediate liquidity and financial flexibility.

Total Debt (Leverage Risk)

Information icon Total debt including both short-term and long-term components. It is needed to assess the company’s leverage and financial risk.

Net Working Capital (Short-Term Health)

Information icon Current assets minus current liabilities, indicating short-term liquidity strength. It is needed to assess whether the company can meet its short-term obligations.

🧱 Balance Sheet Strength

Stockholder Equity (Net Worth)

Information icon Total equity value held by shareholders. It is needed to understand the net worth of the company from the owners’ perspective.

Total Assets (Asset Base)

Information icon The full value of everything the company owns, including cash, inventory, equipment, and investments. It is needed to understand the resource base used to generate revenue.

Income Before Tax (Pre-Tax Earnings)

Information icon Income before provision for income taxes. It is needed to analyze profitability independent of tax structures.

⚙️ Cost & Drag Factors

Cost of Revenue (Production Cost)

Information icon Direct costs required to produce and deliver the products or services sold. It is needed to assess efficiency in production and service delivery.

Total Operating Expenses (Operating Cost)

Information icon Indirect costs of running the business such as salaries, marketing, and administration. It is needed to understand how much it costs to sustain ongoing business operations.

Income Tax Expense (Tax Drag)

Information icon Amount of taxes paid or payable to the government. It is needed to evaluate the impact of taxation on overall profitability.

About Cabaletta Bio Inc

Exchange NASDAQ
Headquarters Philadelphia, PA, United States
IPO Launch date 2019-10-25
Co-Founder, Chairman, CEO & President Dr. Steven A. Nichtberger M.D.
Sector Healthcare
Industry Biotechnology
Full time employees 154
Full time employees 154

Cabaletta Bio, Inc., a clinical-stage biotechnology company, focuses on the discovery and development of engineered T cell therapies for patients with autoimmune diseases. The company's lead product candidate is resecabtagene autoleucel, a 4-1BB co-stimulatory domain-containing fully human CD19-CAR T, which is in Phase 1/2 clinical trials for the treatment of dermatomyositis, anti-synthetase syndrome, immune-mediated necrotizing myopathy, juvenile myositis, lupus nephritis, systemic lupus erythematosus, relapsing and progressive multiple sclerosis, mucocutaneous and mucosal pemphigus vulgaris (PV), systemic sclerosis, and generalized myasthenia gravis. It also develops DSG3-CAART, a CAAR T cell therapy that is in Phase 1 clinical trial for the treatment of mucosal PV; and MuSK-CAART, an investigational cell therapy in Phase 1 trial for treating patients with anti-muscle-specific kinase (MuSK) antibody positive myasthenia gravis. It has collaborations with the University of Pennsylvania and the Children's Hospital of Philadelphia; Nanjing IASO Biotherapeutics Co., Ltd; Oxford Biomedica; Autolus Holdings (UK) Limited; and WuXi Advanced Therapies, Inc. The company was formerly known as Tycho Therapeutics, Inc. and changed its name to Cabaletta Bio, Inc. in August 2018. Cabaletta Bio, Inc. was incorporated in 2017 and is headquartered in Philadelphia, Pennsylvania.