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Kyverna Therapeutics, Inc. Common Stock(KYTX)
Advisory History & Simulated Performance *
*as per simulation (see disclosures)- ALL
- 1Y
- 1M
- 1W
- BUY Advisory
- SELL Advisory (Profit)
- SELL Advisory (Loss)
- Profit
- Loss
- PASS (Skip)
Stock price based on last close Advisory Performance History (Simulated)
Upturn Advisory & Investor View for KYTX
11/13/2026: KYTX (1-star) is currently NOT-A-BUY. Pass it for now.
Kyverna Therapeutics is a clinical-stage biotechnology company focused on developing engineered CAR-T cell therapies for patients with autoimmune diseases. Its primary strength lies in its specialized technology platform and lead program, KYV-101, which aims to provide high-precision treatment for conditions like lupus nephritis. While the company holds a promising position in a high-growth sector, it faces significant risks, including the absence of approved products and intense competition from large pharmaceutical incumbents. The company is best suited for growth-oriented investors who can tolerate the high volatility and binary outcomes typical of clinical-stage biotech. Key developments to monitor include upcoming clinical trial data and progress in manufacturing scaling.
How to Read the Upturn Advisory
The Upturn Star Rating and the current BUY, SELL, or PASS advisory are generated by Upturn’s AI advisory engine based on proprietary signal analysis, price behavior, advisory history, and historical signal performance.
Company fundamentals, valuation, risks, and news provide supporting context about the business.
Investor Fit
| Investor style | Fit | Why |
|---|---|---|
| Growth investor | Strong fit | The company offers high-risk, high-reward exposure to the emerging field of autoimmune cell therapy. |
| Momentum investor | Mixed fit | Momentum is highly dependent on clinical trial catalysts and positive data readouts. |
| Value investor | Weak fit | The company lacks current earnings, making traditional value metrics inapplicable. |
| Dividend investor | Weak fit | No dividend payments are made as the company focuses on R&D. |
| Low-risk investor | Weak fit | Clinical-stage biotech involves significant volatility and binary risk. |
Risk Profile
| Risk factor | Level | Why it matters |
|---|---|---|
| Price volatility | High | Biotech stocks are highly sensitive to clinical data and regulatory news. |
| Valuation risk | High | Valuations are driven by speculative future cash flows from unapproved drugs. |
| Competition risk (cell therapy) | Medium / high | Larger companies with more resources are aggressively entering the autoimmune space. |
| Business quality | Medium | The company has strong scientific potential but lacks a proven commercial product. |
| Dividend income | Low / none | The company is in a capital-intensive growth phase. |
| Execution risk | High | The ability to successfully manufacture and scale complex cell therapies is a major hurdle. |
Key Highlights
Company Size Small-Cap Stock | Market Capitalization 311.07M USD | Price to earnings Ratio - | 1Y Target Price 30.4 |
Price to earnings Ratio - | 1Y Target Price 30.4 | ||
Volume (30-day avg) 849.6K shares | Beta 2.13 | 52 Weeks Range 4.50 - 13.67 | Updated Date 11/13/2026 |
52 Weeks Range 4.50 - 13.67 | Updated Date 11/13/2026 | ||
Dividends yield (FY) - | Basic EPS (TTM) -2.93 |
Sector & Industry Intelligence
Sector
Healthcare
Bullish- Sentiment
- Strong Bullish
- Momentum
- Momentum Steady
- BUY participation
- 62.6%
- Active BUY / eligible
- 72 / 115
- 30-Day BUY Count Change
- +35
- Market state
- Strong Bullish
The number of qualifying BUY stocks has remained relatively stable.
Industry
Biotechnology
- BUY participation
- 45.5%
- Active BUY / eligible
- 20 / 44
- 30-Day BUY Count Change
- +13
Sector signal summarizes BUY breadth conditions for the sector. It does not override this stock’s BUY, SELL, or PASS advisory.
Price Behavior
Steep Decline
The stock price has dropped sharply with strong downward pressure.
Choppy
The stock has experienced frequent reversals and pronounced short-term price swings.
Analysis of Past Performance
Type Stock | Historic Profit -45.28% | Avg. Invested days 13 | Today’s Advisory PASS |
Upturn Advisory Rating  | Upturn Advisory Performance  2.0 | Stock Returns Performance  1.0 |
| Profits based on simulation | Last Close 11/13/2026 |
Upturn Scorecard
Upturn Star Rating 
Company Fundamentals
Financial Health Rating
Growth Momentum Score
Ownership
Top 5 Institutional Investors
Unit Economics (Per $1K Revenue)
Economic Dimensions
Quantitative Style Profile
Style Classification
Quality Focused
How Company Makes Money
| Business area | What it includes | Retail investor read |
|---|---|---|
| Cell Therapy Development | Clinical trial development and intellectual property related to KYV-101 and pipeline assets. | The company generates no product revenue yet; value is tied to the success of its experimental drug trials. |
Valuation
Trailing PE - | Forward PE - | Enterprise Value 150.21M | Price to Sales(TTM) 3513.34 |
Enterprise Value 150.21M | Price to Sales(TTM) 3513.34 | ||
Enterprise Value to Revenue 3341.48 | Enterprise Value to EBITDA - | Shares Outstanding 61.84M | Shares Floating 36.07M |
Shares Outstanding 61.84M | Shares Floating 36.07M | ||
Percent Insiders 6.98 | Percent Institutions 82.24 |
Financial Metrics
🧭 Investment Snapshot
Total Revenue (Scale)
Total money earned from selling products or services before any costs. It is needed to understand the scale of the business and its ability to generate income.
Net Income (Profit)
Final profit after all expenses, interest, and taxes are deducted. It is needed to determine the overall profitability available to shareholders.
Free Cash Flow (Cash Strength)
Cash remaining after operating activities and capital expenditures, showing cash available for growth. It is needed to evaluate the company’s ability to invest, pay dividends, or reduce debt.
📈 Growth & Strength
Operating Income (Core Profit)
Profit from core operations after deducting all operating expenses. It is needed to measure how efficiently the company runs its primary business activities.
EBITDA (Cash Earnings)
Earnings before interest, taxes, depreciation, and amortization, indicating operating cash potential. It is needed to compare operating performance across companies without accounting or financing differences.
Gross Profit (Unit Profitability)
Revenue minus cost of revenue, showing profit after direct production costs. It is needed to evaluate core business profitability before overhead expenses.
🛡️ Financial Safety
Cash (Liquidity Buffer)
Total cash and cash equivalents on hand. It is needed to evaluate immediate liquidity and financial flexibility.
Total Debt (Leverage Risk)
Total debt including both short-term and long-term components. It is needed to assess the company’s leverage and financial risk.
Net Working Capital (Short-Term Health)
Current assets minus current liabilities, indicating short-term liquidity strength. It is needed to assess whether the company can meet its short-term obligations.
🧱 Balance Sheet Strength
Stockholder Equity (Net Worth)
Total equity value held by shareholders. It is needed to understand the net worth of the company from the owners’ perspective.
Total Assets (Asset Base)
The full value of everything the company owns, including cash, inventory, equipment, and investments. It is needed to understand the resource base used to generate revenue.
Income Before Tax (Pre-Tax Earnings)
Income before provision for income taxes. It is needed to analyze profitability independent of tax structures.
⚙️ Cost & Drag Factors
Cost of Revenue (Production Cost)
Direct costs required to produce and deliver the products or services sold. It is needed to assess efficiency in production and service delivery.
Total Operating Expenses (Operating Cost)
Indirect costs of running the business such as salaries, marketing, and administration. It is needed to understand how much it costs to sustain ongoing business operations.
Income Tax Expense (Tax Drag)
Amount of taxes paid or payable to the government. It is needed to evaluate the impact of taxation on overall profitability.
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