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Upturn AI SWOT - About
CASI Pharmaceuticals Inc (CASI)
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Upturn Advisory Summary
06/18/2025: CASI (1-star) is currently NOT-A-BUY. Pass it for now.
Upturn Star Rating
Not Recommended Performance
These Stocks/ETFs, based on Upturn Advisory, consistently fall short of market performance, signaling caution before investing.
Analysis of Past Performance
Type Stock | Historic Profit 81.96% | Avg. Invested days 38 | Today’s Advisory PASS |
Upturn Star Rating | Upturn Advisory Performance  3.0 | Stock Returns Performance  4.0 |
| Profits based on simulation | Last Close 06/18/2025 |
Key Highlights
Company Size Small-Cap Stock | Market Capitalization 22.77M USD | Price to earnings Ratio - | 1Y Target Price 4 |
Price to earnings Ratio - | 1Y Target Price 4 | ||
Volume (30-day avg) 191414 | Beta 0.63 | 52 Weeks Range 1.10 - 7.67 | Updated Date 06/19/2025 |
52 Weeks Range 1.10 - 7.67 | Updated Date 06/19/2025 | ||
Dividends yield (FY) - | Basic EPS (TTM) -2.35 |
Analyzing Revenue: Products, Geography and Growth
Revenue by Products
Earnings Date
Report Date - | When - | Estimate - | Actual - |
Profitability
Profit Margin -129.05% | Operating Margin (TTM) -163.99% |
Management Effectiveness
Return on Assets (TTM) -50.88% | Return on Equity (TTM) -1094.5% |
Valuation
Trailing PE - | Forward PE - | Enterprise Value 26863182 | Price to Sales(TTM) 0.73 |
Enterprise Value 26863182 | Price to Sales(TTM) 0.73 | ||
Enterprise Value to Revenue 0.86 | Enterprise Value to EBITDA 0.07 | Shares Outstanding 15492800 | Shares Floating 6366252 |
Shares Outstanding 15492800 | Shares Floating 6366252 | ||
Percent Insiders 41.45 | Percent Institutions 23.64 |
Analyst Ratings
Rating 4 | Target Price 4 | Buy 1 | Strong Buy - |
Buy 1 | Strong Buy - | ||
Hold - | Sell - | Strong Sell - | |
Strong Sell - |
Upturn AI SWOT
CASI Pharmaceuticals Inc
Company Overview
History and Background
CASI Pharmaceuticals Inc. was founded in 1991. Initially focused on specialty pharmaceuticals in China, it has shifted its focus to developing and commercializing innovative therapeutics and pharmaceutical products across a broad spectrum of areas including hematology-oncology.
Core Business Areas
- Hematology-Oncology: Focuses on the development and commercialization of pharmaceutical products for the treatment of hematological malignancies and solid tumors.
Leadership and Structure
Wei-Wu He, Ph.D., is the Chairman and CEO. The company operates with a structure common for biotechnology companies, consisting of R&D, clinical development, regulatory affairs, and commercial operations.
Top Products and Market Share
Key Offerings
- EVOMELA (melphalan for injection): An intravenous formulation of melphalan used as a high-dose conditioning treatment prior to stem cell transplantation in patients with multiple myeloma. Market share data is unavailable. Competitors include generics such as melphalan.
- MARQIBO (vincristine sulfate liposome injection): A sphingomyelin/cholesterol liposome-encapsulated formulation of vincristine sulfate used to treat adults with Philadelphia chromosome-negative acute lymphoblastic leukemia (Ph- ALL). Market share data unavailable. Competitors include generic vincristine.
- CNCT19 (CIDR-101/oclacitinib):: An anti-CD19 chimeric antigen receptor (CAR)-T cell therapy being developed in China to treat relapsed or refractory B-cell acute lymphoblastic leukemia (B-ALL) and relapsed or refractory diffuse large B-cell lymphoma (DLBCL). Market share data unavailable. Competitors include autologous anti-CD19 CAR-T cell therapies such as Kymriah and Yescarta.
- BI-1206: A monoclonal antibody designed to block CD47 which is being developed for the treatment of advanced hematologic malignancies and solid tumors. Market share data unavailable. Competitors include magrolimab.
Market Dynamics
Industry Overview
The biopharmaceutical industry is characterized by high R&D costs, lengthy regulatory approval processes, and intense competition. The market for oncology drugs is rapidly growing, driven by an aging population and advancements in personalized medicine.
Positioning
CASI Pharmaceuticals is positioned as a specialty pharmaceutical company focused on bringing innovative oncology products to market, particularly in China and the US. Their strategy involves both developing proprietary products and licensing or acquiring promising candidates.
Total Addressable Market (TAM)
The global oncology drugs market is expected to reach hundreds of billions of dollars. CASI is positioned to capture a portion of this TAM with its portfolio of oncology-focused therapeutics. Specific TAM is difficult to define due to drug approval specifics, indications and global rollout.
Upturn SWOT Analysis
Strengths
- Focus on oncology therapeutics
- Strategic partnerships for product development and commercialization
- Experienced management team
- Access to the Chinese pharmaceutical market
- Portfolio of approved and pipeline products
Weaknesses
- Limited financial resources compared to larger pharmaceutical companies
- Reliance on partnerships for revenue generation
- Dependence on regulatory approvals for product commercialization
- Geographical concentration of operations
Opportunities
- Expanding product portfolio through strategic acquisitions and licensing deals
- Entering new geographical markets
- Developing innovative therapies targeting unmet medical needs in oncology
- Leveraging the growing demand for oncology drugs in China
- Capitalizing on advancements in personalized medicine and targeted therapies
Threats
- Competition from established pharmaceutical companies
- Regulatory hurdles and delays in product approvals
- Pricing pressures and reimbursement challenges
- Intellectual property infringement
- Economic downturns affecting healthcare spending
Competitors and Market Share
Key Competitors
- JAZZ (JAZZ)
- MRTX (MRTX)
- ARVN (ARVN)
Competitive Landscape
CASI faces strong competition from larger pharmaceutical companies with greater resources and established market positions. CASI differentiates itself through a focus on niche oncology markets and strategic partnerships.
Major Acquisitions
Growth Trajectory and Initiatives
Historical Growth: Historical growth is dependent on revenue and product sales, which are not available in this context.
Future Projections: Future growth projections are dependent on market conditions, drug approvals, and commercialization efforts, which are subject to change.
Recent Initiatives: Recent initiatives are centered on progressing clinical development programs, securing regulatory approvals for new products, and expanding commercial operations.
Summary
CASI Pharmaceuticals is a small company with a focus on oncology, leveraging partnerships to develop and commercialize its products, particularly in China. While it has a promising pipeline, its financial resources are limited and it faces significant competition. Approval of lead products is important to drive revenues. CASI needs to successfully navigate the regulatory landscape to ensure commercial success of its portfolio.
Peer Comparison
Sources and Disclaimers
Data Sources:
- Company SEC Filings
- Industry Reports
- Analyst Reports
- Company Website
Disclaimers:
The data and analysis provided are for informational purposes only and should not be considered investment advice. Market share data is approximate and may vary. Financial data is subject to change.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About CASI Pharmaceuticals Inc
Exchange NASDAQ | Headquaters - | ||
IPO Launch date 1996-06-11 | Chairman & CEO Dr. Wei-Wu He Ph.D. | ||
Sector Healthcare | Industry Biotechnology | Full time employees 233 | |
Full time employees 233 | |||
CASI Pharmaceuticals, Inc., a biopharmaceutical company, develops and commercializes therapeutics and pharmaceutical products in the People's Republic of China, the United States, and internationally. It offers EVOMELA, an intravenous formulation of melphalan for use as a conditioning treatment prior to stem cell transplantation and as a palliative treatment for patients with multiple myeloma. The company's hematology/oncology assets in pipeline include CNCT19, an autologous CD19 CAR-T investigative product; BI-1206, an novel anti-Fc"RIIB antibody for the treatment of solid tumors and relapsed/refractory non-hodgkin lymphoma; CB-5339, a novel VCP/p97 inhibitor that focuses on valosin-containing protein (VCP)/p97 as a novel target in protein homeostasis, DNA damage response, and other cellular stress pathways for therapeutic use in the treatment of patients with various malignancies; CID-103, a human IgG1 anti-CD38 monoclonal antibody; and Thiotepa, a chemotherapeutic agent, which has various indications, including use as a conditioning treatment for use prior to certain allogeneic haemopoietic stem cell transplants. It has licensing agreements with Juventas Cell Therapy Ltd.; BioInvent International AB; Black Belt Therapeutics Limited; Cleave Therapeutics, Inc.; and Acrotech Biopharma L.L.C. to develop and commercialize its commercial product EVOMELA. CASI Pharmaceuticals, Inc. was incorporated in 1991 and is based in Beijing, the People's Republic of China.
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