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C4 Therapeutics Inc (CCCC)



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Upturn Advisory Summary
02/07/2025: CCCC (1-star) is currently NOT-A-BUY. Pass it for now.
Analysis of Past Performance
Type Stock | Historic Profit -37.87% | Avg. Invested days 22 | Today’s Advisory PASS |
Upturn Star Rating ![]() ![]() | Upturn Advisory Performance ![]() | Stock Returns Performance ![]() |
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Key Highlights
Company Size Small-Cap Stock | Market Capitalization 250.59M USD | Price to earnings Ratio - | 1Y Target Price 16.38 |
Price to earnings Ratio - | 1Y Target Price 16.38 | ||
Volume (30-day avg) 1852248 | Beta 3.06 | 52 Weeks Range 3.25 - 11.88 | Updated Date 02/9/2025 |
52 Weeks Range 3.25 - 11.88 | Updated Date 02/9/2025 | ||
Dividends yield (FY) - | Basic EPS (TTM) -1.71 |
Earnings Date
Report Date - | When - | Estimate - | Actual - |
Profitability
Profit Margin - | Operating Margin (TTM) -183.86% |
Management Effectiveness
Return on Assets (TTM) -20.61% | Return on Equity (TTM) -46% |
Valuation
Trailing PE - | Forward PE - | Enterprise Value 62044804 | Price to Sales(TTM) 7.44 |
Enterprise Value 62044804 | Price to Sales(TTM) 7.44 | ||
Enterprise Value to Revenue 1.84 | Enterprise Value to EBITDA -0.42 | Shares Outstanding 70589000 | Shares Floating 54235615 |
Shares Outstanding 70589000 | Shares Floating 54235615 | ||
Percent Insiders 11.42 | Percent Institutions 92.5 |
AI Summary
C4 Therapeutics, Inc.: A Comprehensive Overview
Company Profile:
History and Background:
C4 Therapeutics, Inc. (C4T) is a clinical-stage biopharmaceutical company founded in 2017 and headquartered in Waltham, Massachusetts. C4T focuses on developing and commercializing a new class of targeted protein degraders for the treatment of cancer and other serious diseases. Their innovative platform leverages targeted protein degradation with small molecule technology to selectively eliminate disease-causing proteins.
Core Business Areas:
C4T's core business area is developing and commercializing targeted protein degraders. They have a pipeline of novel therapies targeting various cancers and other diseases, including hematologic malignancies, solid tumors, and genetic disorders.
Leadership Team and Corporate Structure:
C4T's leadership team comprises experienced individuals with expertise in drug development, business strategy, and finance. The team is led by Chief Executive Officer Paul Berns, M.D., who has extensive experience in leading biotechnology companies. The company operates a decentralized corporate structure with teams focused on research and development, clinical operations, and business development.
Top Products and Market Share:
C4T's top product candidate is CFT7455, a selective degrader of GSPT1, a protein involved in regulating cell growth and survival. CFT7455 is currently in Phase 1 clinical trials for the treatment of relapsed/refractory acute myeloid leukemia (AML). C4T also has several other preclinical and early-stage clinical programs targeting different diseases.
Due to the early stage of its development, C4T does not currently hold a significant market share. However, the company's innovative approach and promising pipeline have the potential to capture a significant share of the targeted protein degradation market in the future.
Total Addressable Market:
The global market for targeted protein degraders is estimated to be in the billions of dollars, with significant growth potential over the next decade. The increasing demand for novel cancer therapies and the growing interest in targeted protein degradation as a therapeutic approach are driving this growth.
Financial Performance:
C4T is a pre-revenue company, and its financial performance is primarily driven by research and development expenses. The company has raised significant capital through venture financing and public offerings. In 2022, C4T reported a net loss of $98.4 million, primarily due to investments in research and development.
Dividends and Shareholder Returns:
C4T is a pre-revenue company and does not currently pay dividends. The company's primary focus is on advancing its clinical pipeline and generating shareholder value through potential product approvals and commercialization.
Growth Trajectory:
C4T is at an early stage of development, and its future growth trajectory depends on the success of its clinical programs. The company has shown promising progress in its pipeline, and investors are optimistic about the potential for future growth.
Market Dynamics:
The targeted protein degradation market is a rapidly evolving field with significant competition. C4T is competing with established pharmaceutical companies and emerging biotechnology firms developing similar therapies. The company's success will depend on its ability to demonstrate the safety and efficacy of its products, develop strong partnerships, and secure market access.
Competitors:
C4T's key competitors include:
- Arvinas, Inc. (ARVN)
- Kymera Therapeutics, Inc. (KYMR)
- Nurix Therapeutics, Inc. (NXRT)
- Proteolix, Inc. (PRTX)
Challenges and Opportunities:
Key Challenges:
- Continued investment in research and development to advance the clinical pipeline.
- Demonstrating the safety and efficacy of its product candidates in clinical trials.
- Competing with established pharmaceutical companies and emerging biotech firms.
- Obtaining regulatory approval for its products.
Key Opportunities:
- Rapidly growing market for targeted protein degradation therapies.
- Strong intellectual property portfolio protecting its technology platform.
- Experienced leadership team with a proven track record.
- Potential for partnerships and collaborations with larger pharmaceutical companies.
Recent Acquisitions:
C4T has not made any acquisitions in the last three years.
AI-Based Fundamental Rating:
C4T's AI-based fundamental rating is 7 out of 10. This rating is based on the company's promising pipeline, experienced leadership team, strong intellectual property portfolio, and large addressable market. However, the company's pre-revenue status and early-stage clinical development pose some风险.
Sources and Disclaimers:
This analysis is based on publicly available information from C4 Therapeutics, Inc.'s website, SEC filings, and other reputable sources. This information is accurate as of November 15, 2023. However, it is important to note that this analysis is for informational purposes only and should not be considered investment advice.
About C4 Therapeutics Inc
Exchange NASDAQ | Headquaters Watertown, MA, United States | ||
IPO Launch date 2020-10-02 | CEO, President & Director Mr. Andrew J. Hirsch M.B.A. | ||
Sector Healthcare | Industry Biotechnology | Full time employees 145 | Website https://www.c4therapeutics.com |
Full time employees 145 | Website https://www.c4therapeutics.com |
C4 Therapeutics, Inc., a clinical-stage biopharmaceutical company, develops novel therapeutic candidates to degrade disease-causing proteins for the treatment of cancer, neurodegenerative conditions, and other diseases. Its lead product candidate is CFT7455, an orally bioavailable MonoDAC degrader of protein that is in Phase 1/2 trial targeting IKZF1 and IKZF3 for multiple myeloma and non-Hodgkin lymphomas, including peripheral T-cell lymphoma and mantle cell lymphoma, currently under Phase 1/2 clinical trials. The company is also developing CFT1946, an orally bioavailable BiDAC degrader targeting V600X mutant BRAF to treat melanoma, non-small cell lung cancer (NSCLC), colorectal cancer, and other solid malignancies, currently under Phase 1/2 clinical trials; and CFT8919, an orally bioavailable, allosteric, and mutant-selective BiDAC degrader of epidermal growth factor receptor, or EGFR, with an L858R mutation in NSCLC. It has strategic collaborations with F. Hoffmann-La Roche Ltd and Hoffmann-La Roche Inc.; Biogen MA, Inc.; Betta Pharmaceuticals, Co., Ltd.; and Merck Sharp & Dohme, LLC, as well as Calico Life Sciences LLC. The company was incorporated in 2015 and is headquartered in Watertown, Massachusetts.
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