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Kymera Therapeutics Inc(KYMR)
Advisory History & Simulated Performance *
*as per simulation (see disclosures)- ALL
- 1Y
- 1M
- 1W
- BUY Advisory
- SELL Advisory (Profit)
- SELL Advisory (Loss)
- Profit
- Loss
- PASS (Skip)
Stock price based on last close Advisory Performance History (Simulated)
Upturn Advisory & Investor View for KYMR
10/23/2026: KYMR (4-star) is currently NOT-A-BUY. Pass it for now.
Kymera Therapeutics is a clinical-stage biotechnology company developing targeted protein degraders to address serious diseases in immunology and oncology. Its primary strength lies in its Pegasus platform, which enables the discovery of drugs for challenging therapeutic targets. The company's growth story centers on its lead candidates, KT-474 and KT-333, and strategic partnerships like the one with Sanofi. Risks include the typical challenges faced by clinical-stage firms, such as binary clinical trial outcomes, high cash burn, and intense competition from other biotech innovators. The stock is a suitable high-risk, high-reward investment for growth-oriented investors who should closely monitor upcoming clinical data releases and regulatory milestones.
How to Read the Upturn Advisory
The Upturn Star Rating and the current BUY, SELL, or PASS advisory are generated by Upturn’s AI advisory engine based on proprietary signal analysis, price behavior, advisory history, and historical signal performance.
Company fundamentals, valuation, risks, and news provide supporting context about the business.
Investor Fit
| Investor style | Fit | Why |
|---|---|---|
| Growth investor | Strong fit | Kymera is a classic high-growth potential biotech play focused on disruptive medical technology. |
| Momentum investor | Strong fit while signal remains positive | The stock can exhibit high momentum based on clinical trial updates and partnership announcements. |
| Value investor | Weak fit | The company lacks current earnings and traditional value metrics, making it unsuitable for conservative value strategies. |
| Dividend investor | Weak fit | Kymera pays no dividends and reinvests all capital into R&D. |
| Low-risk investor | Weak fit | The extreme volatility associated with clinical-stage biotech stocks poses significant risks to low-risk investors. |
Risk Profile
| Risk factor | Level | Why it matters |
|---|---|---|
| Price volatility | High | Clinical results often trigger large, binary stock price movements. |
| Valuation risk | High | Valuations are highly speculative and contingent on long-term drug development success. |
| Competition risk (TPD/Biotech peers) | Medium / high | Many companies are racing to develop similar targeted protein degradation therapies. |
| Business quality | Medium | The company has a strong platform but lacks the revenue stability of mature commercial biotech entities. |
| Dividend income | Low / none | The company does not pay dividends. |
| Execution risk | High | Success depends entirely on the ability to successfully navigate complex clinical trials and regulatory approval. |
Price Behavior
Strong Uptrend
The stock has maintained a strong upward price trend across the last three quarters.
Moderately Choppy
The stock has experienced noticeable price swings while retaining some directional structure.
Analysis of Past Performance
Type Stock | Historic Profit 98.77% | Avg. Invested days 33 | Today’s Advisory PASS |
Upturn Advisory Rating  | Upturn Advisory Performance  2.0 | Stock Returns Performance  4.0 |
| Profits based on simulation | Last Close 10/23/2026 |
Upturn Scorecard
Upturn Star Rating 
Company Fundamentals
Financial Health Rating
Growth Momentum Score
Ownership
Top 5 Institutional Investors
Unit Economics (Per $1K Revenue)
Economic Dimensions
Quantitative Style Profile
Style Classification
Quality Focused
Key Highlights
Company Size Mid-Cap Stock | Market Capitalization 9.11B USD | Price to earnings Ratio - | 1Y Target Price 139.35 |
Price to earnings Ratio - | 1Y Target Price 139.35 | ||
Volume (30-day avg) 841.4K shares | Beta 1.98 | 52 Weeks Range 55.66 - 130.05 | Updated Date 10/24/2026 |
52 Weeks Range 55.66 - 130.05 | Updated Date 10/24/2026 | ||
Dividends yield (FY) - | Basic EPS (TTM) -3.25 |
How Company Makes Money
| Business area | What it includes | Retail investor read |
|---|---|---|
| Collaboration and Licensing Agreements | Milestone payments and R&D funding from partners like Sanofi. | Revenue is not from sales of drugs but from payments made by large pharma partners to develop Kymera's technology. |
Valuation
Trailing PE - | Forward PE - | Enterprise Value 3.42B | Price to Sales(TTM) 86.77 |
Enterprise Value 3.42B | Price to Sales(TTM) 86.77 | ||
Enterprise Value to Revenue 76.58 | Enterprise Value to EBITDA -9.49 | Shares Outstanding 82.26M | Shares Floating 66.04M |
Shares Outstanding 82.26M | Shares Floating 66.04M | ||
Percent Insiders 2.12 | Percent Institutions 119.39 |
Financial Metrics
🧭 Investment Snapshot
Total Revenue (Scale)
Total money earned from selling products or services before any costs. It is needed to understand the scale of the business and its ability to generate income.
Net Income (Profit)
Final profit after all expenses, interest, and taxes are deducted. It is needed to determine the overall profitability available to shareholders.
Free Cash Flow (Cash Strength)
Cash remaining after operating activities and capital expenditures, showing cash available for growth. It is needed to evaluate the company’s ability to invest, pay dividends, or reduce debt.
📈 Growth & Strength
Operating Income (Core Profit)
Profit from core operations after deducting all operating expenses. It is needed to measure how efficiently the company runs its primary business activities.
EBITDA (Cash Earnings)
Earnings before interest, taxes, depreciation, and amortization, indicating operating cash potential. It is needed to compare operating performance across companies without accounting or financing differences.
Gross Profit (Unit Profitability)
Revenue minus cost of revenue, showing profit after direct production costs. It is needed to evaluate core business profitability before overhead expenses.
🛡️ Financial Safety
Cash (Liquidity Buffer)
Total cash and cash equivalents on hand. It is needed to evaluate immediate liquidity and financial flexibility.
Total Debt (Leverage Risk)
Total debt including both short-term and long-term components. It is needed to assess the company’s leverage and financial risk.
Net Working Capital (Short-Term Health)
Current assets minus current liabilities, indicating short-term liquidity strength. It is needed to assess whether the company can meet its short-term obligations.
🧱 Balance Sheet Strength
Stockholder Equity (Net Worth)
Total equity value held by shareholders. It is needed to understand the net worth of the company from the owners’ perspective.
Total Assets (Asset Base)
The full value of everything the company owns, including cash, inventory, equipment, and investments. It is needed to understand the resource base used to generate revenue.
Income Before Tax (Pre-Tax Earnings)
Income before provision for income taxes. It is needed to analyze profitability independent of tax structures.
⚙️ Cost & Drag Factors
Cost of Revenue (Production Cost)
Direct costs required to produce and deliver the products or services sold. It is needed to assess efficiency in production and service delivery.
Total Operating Expenses (Operating Cost)
Indirect costs of running the business such as salaries, marketing, and administration. It is needed to understand how much it costs to sustain ongoing business operations.
Income Tax Expense (Tax Drag)
Amount of taxes paid or payable to the government. It is needed to evaluate the impact of taxation on overall profitability.
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