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Kymera Therapeutics Inc (KYMR)

Upturn stock ratingUpturn stock rating
$46.2
Last Close (24-hour delay)
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PASS
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Upturn Stock infoUpturn Stock info Stock price based on last close
*as per simulation
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Time period over
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Upturn Advisory Summary

09/11/2025: KYMR (1-star) is currently NOT-A-BUY. Pass it for now.

Upturn Star Rating

rating

Not Recommended Performance

These Stocks/ETFs, based on Upturn Advisory, consistently fall short of market performance, signaling caution before investing.

Number of Analysts

rating

20 Analysts rated it

Well-followed company, solid analyst reports, reliable data for confident investing.

1 Year Target Price $62.21

1 Year Target Price $62.21

Analysts Price Target For last 52 week
$62.21 Target price
52w Low $19.45
Current$46.2
52w High $53.27

Analysis of Past Performance

Type Stock
Historic Profit 72.93%
Avg. Invested days 31
Today’s Advisory PASS
Upturn Star Rating Upturn stock ratingUpturn stock rating
Upturn Advisory Performance Upturn Advisory Performance 2.0
Stock Returns Performance Upturn Returns Performance 4.0
Upturn Profits based on simulationUpturn Profits based on simulation Profits based on simulation
Upturn Profits based on simulationUpturn Profits based on simulation Last Close 09/11/2025

Key Highlights

Company Size Mid-Cap Stock
Market Capitalization 3.30B USD
Price to earnings Ratio -
1Y Target Price 62.21
Price to earnings Ratio -
1Y Target Price 62.21
Volume (30-day avg) 20
Beta 2.18
52 Weeks Range 19.45 - 53.27
Updated Date 09/12/2025
52 Weeks Range 19.45 - 53.27
Updated Date 09/12/2025
Dividends yield (FY) -
Basic EPS (TTM) -3.49

Earnings Date

Report Date -
When -
Estimate -
Actual -

Profitability

Profit Margin -
Operating Margin (TTM) -736.82%

Management Effectiveness

Return on Assets (TTM) -19.92%
Return on Equity (TTM) -33.26%

Valuation

Trailing PE -
Forward PE -
Enterprise Value 2528984517
Price to Sales(TTM) 73.88
Enterprise Value 2528984517
Price to Sales(TTM) 73.88
Enterprise Value to Revenue 56.56
Enterprise Value to EBITDA -9.49
Shares Outstanding 71497600
Shares Floating 46960337
Shares Outstanding 71497600
Shares Floating 46960337
Percent Insiders 2.53
Percent Institutions 109.99

ai summary icon Upturn AI SWOT

Kymera Therapeutics Inc

stock logo

Company Overview

overview logo History and Background

Kymera Therapeutics Inc. was founded in 2016 and focuses on developing protein degradation therapies. It has achieved milestones in advancing its pipeline of targeted protein degraders and securing strategic partnerships.

business area logo Core Business Areas

  • Targeted Protein Degradation: Kymera focuses on discovering and developing novel small molecule therapeutics that selectively degrade disease-causing proteins. This is their primary and almost sole business area.

leadership logo Leadership and Structure

The leadership team consists of experienced executives in drug discovery and development. The organizational structure is typical of a biotech company, with research, development, and commercial functions.

Top Products and Market Share

overview logo Key Offerings

  • KT-474 (IRAK4 degrader): KT-474 is a lead product candidate targeting IRAK4, currently in clinical trials for immune-inflammatory diseases. Market share data is not yet available as the product is pre-commercial. Competitors are companies developing therapies for immune-inflammatory diseases, including those targeting IRAK4 with different mechanisms (e.g., inhibitors).
  • STAT3 degrader: Kymera is developing a STAT3 degrader. It is in preclinical stages and is intended for specific types of cancer. Market share data is not yet available. Competitors are companies developing STAT3 inhibitors or other cancer therapies.

Market Dynamics

industry overview logo Industry Overview

The industry is focused on developing innovative therapies for diseases with unmet medical needs. Targeted protein degradation is an emerging field with significant potential.

Positioning

Kymera is a leader in the targeted protein degradation space, with a proprietary platform and a pipeline of promising drug candidates. Its competitive advantage lies in its expertise and intellectual property in this field.

Total Addressable Market (TAM)

The TAM for targeted protein degradation therapies is potentially very large, addressing various diseases including oncology and immunology. Kymera is positioned to capture a significant portion of this market if its products are successful.

Upturn SWOT Analysis

Strengths

  • Pioneer in targeted protein degradation
  • Proprietary platform technology
  • Strong pipeline of drug candidates
  • Experienced management team
  • Strategic partnerships with established pharmaceutical companies

Weaknesses

  • High risk of drug development failure
  • Limited commercial experience
  • Dependence on key partnerships
  • Cash burn rate associated with R&D
  • Relatively early stage compared to larger pharmaceutical companies.

Opportunities

  • Expanding into new therapeutic areas
  • Securing additional partnerships
  • Acquiring complementary technologies
  • Advancing pipeline candidates through clinical trials
  • Potential for breakthrough therapies in diseases with unmet needs.

Threats

  • Competition from other drug developers
  • Regulatory hurdles
  • Patent challenges
  • Clinical trial failures
  • Changes in the market for targeted protein degradation therapies.

Competitors and Market Share

competitor logo Key Competitors

  • VRTX
  • ARRY
  • GILD
  • BMY
  • MRK

Competitive Landscape

Kymera's competitive advantage lies in its specialized focus on targeted protein degradation. However, it faces competition from larger pharmaceutical companies with broader pipelines and greater resources. Market share is negligible while in development stage.

Growth Trajectory and Initiatives

Historical Growth: Historical growth is measured by pipeline advancement and partnership deals.

Future Projections: Future growth is contingent on clinical trial success and regulatory approvals. Analyst estimates vary based on pipeline progress.

Recent Initiatives: Recent initiatives include advancing KT-474 into later-stage clinical trials and expanding its pipeline through internal discovery and partnerships.

Summary

Kymera Therapeutics is a pioneering company in the field of targeted protein degradation, with a promising pipeline of novel therapeutics. As a pre-revenue company, its success depends on the progress of its clinical trials and regulatory approvals. The company's strategic partnerships and strong platform technology provide a solid foundation, but it faces risks associated with drug development and competition from larger pharmaceutical companies.

Peer Comparison

Sources and Disclaimers

Data Sources:

  • SEC Filings
  • Company Website
  • Analyst Reports

Disclaimers:

This analysis is for informational purposes only and does not constitute investment advice. Market share values are approximations and subject to change.

Upturn AI SummarizationUpturn AI Summarization AI Summarization is directionally correct and might not be accurate.

Upturn AI SummarizationUpturn AI Summarization Summarized information shown could be a few years old and not current.

Upturn AI SummarizationUpturn AI Summarization Fundamental Rating based on AI could be based on old data.

Upturn AI SummarizationUpturn AI Summarization AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.

About Kymera Therapeutics Inc

Exchange NASDAQ
Headquaters Watertown, MA, United States
IPO Launch date 2020-08-21
Co-Founder, President, CEO & Director Dr. Nello Mainolfi M.D., Ph.D.
Sector Healthcare
Industry Biotechnology
Full time employees 218
Full time employees 218

Kymera Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on discovering and developing small molecule therapeutics that selectively degrade disease-causing proteins by harnessing the body's own natural protein degradation system. It engages in developing IRAK4 program, which is in Phase II clinical trial for the treatment of immunology-inflammation diseases, including hidradenitis suppurativa and atopic dermatitis. The company also develops STAT6, a type 2 inflammation in allergic and atopic diseases; and TYK2 to treat autoimmune and inflammatory diseases. The company has a strategic alliance with Sanofi S.A. for the development of drug candidates targeting IRAK4 outside of the oncology and immuno-oncology fields. Kymera Therapeutics, Inc. was incorporated in 2015 and is headquartered in Watertown, Massachusetts.