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Upturn stock ratingUpturn stock rating
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Codexis Inc (CDXS)

Upturn stock ratingUpturn stock rating
$2.72
Last Close (24-hour delay)
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PASS
  • BUY Advisory
  • SELL Advisory (Profit)​
  • SELL Advisory (Loss)​
  • Profit
  • Loss
  • Pass (Skip investing)
Upturn Stock infoUpturn Stock info Stock price based on last close
*as per simulation
(see disclosures)
Time period over
  • ALL
  • YEAR
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Upturn Advisory Summary

08/28/2025: CDXS (1-star) is currently NOT-A-BUY. Pass it for now.

Upturn Star Rating

rating

Not Recommended Performance

These Stocks/ETFs, based on Upturn Advisory, consistently fall short of market performance, signaling caution before investing.

Number of Analysts

rating

7 Analysts rated it

Limited analyst coverage, niche firm, research info may be scarce.

1 Year Target Price $7.08

1 Year Target Price $7.08

Analysts Price Target For last 52 week
$7.08 Target price
52w Low $1.9
Current$2.72
52w High $6.08

Analysis of Past Performance

Type Stock
Historic Profit -25.29%
Avg. Invested days 27
Today’s Advisory PASS
Upturn Star Rating Upturn stock ratingUpturn stock rating
Upturn Advisory Performance Upturn Advisory Performance 3.0
Stock Returns Performance Upturn Returns Performance 1.0
Upturn Profits based on simulationUpturn Profits based on simulation Profits based on simulation
Upturn Profits based on simulationUpturn Profits based on simulation Last Close 08/28/2025

Key Highlights

Company Size Small-Cap Stock
Market Capitalization 245.53M USD
Price to earnings Ratio -
1Y Target Price 7.08
Price to earnings Ratio -
1Y Target Price 7.08
Volume (30-day avg) 7
Beta 2.55
52 Weeks Range 1.90 - 6.08
Updated Date 08/28/2025
52 Weeks Range 1.90 - 6.08
Updated Date 08/28/2025
Dividends yield (FY) -
Basic EPS (TTM) -0.8

Analyzing Revenue: Products, Geography and Growth

Revenue by Products

Product revenue - Year on Year

Revenue by Geography

Geography revenue - Year on Year

Earnings Date

Report Date 2025-08-13
When -
Estimate -0.19
Actual -0.16

Profitability

Profit Margin -113.67%
Operating Margin (TTM) -83.91%

Management Effectiveness

Return on Assets (TTM) -26.48%
Return on Equity (TTM) -111%

Valuation

Trailing PE -
Forward PE 138.89
Enterprise Value 243664128
Price to Sales(TTM) 4.3
Enterprise Value 243664128
Price to Sales(TTM) 4.3
Enterprise Value to Revenue 4.26
Enterprise Value to EBITDA -10.67
Shares Outstanding 90267504
Shares Floating 68485925
Shares Outstanding 90267504
Shares Floating 68485925
Percent Insiders 2.28
Percent Institutions 80.71

ai summary icon Upturn AI SWOT

Codexis Inc

stock logo

Company Overview

overview logo History and Background

Codexis, Inc. was founded in 2002. It's evolved from a computational protein design company to a leader in enzyme engineering, developing high-performance enzymes for various industries.

business area logo Core Business Areas

  • Codexis BioSolutionsu2122: Development and sale of novel enzymes to enable the synthesis of small molecule therapeutics and other fine chemicals. These enzymes are used by pharmaceutical companies to improve manufacturing processes.
  • Sustainable Manufacturing: Enzymes for biocatalytic manufacturing solutions, supporting sustainable and cost-effective chemical processes, including applications beyond pharmaceuticals.
  • Life Science Tools: Development of reagents used in next-generation sequencing (NGS) workflows to improve accuracy and performance.

leadership logo Leadership and Structure

The company has a CEO, board of directors, and a leadership team overseeing R&D, commercial operations, and finance. Organizational structure is function-based to promote expertise and efficiency.

Top Products and Market Share

overview logo Key Offerings

  • Codexu00ae HiFi Hot Start DNA Polymerase: A high-fidelity polymerase used in PCR for NGS applications. Improves accuracy and reduces errors in DNA amplification. The market share is not publicly disclosed. Competitors include Thermo Fisher Scientific (TMO), Illumina (ILMN), and QIAGEN (QGEN).
  • Enzyme engineering services for pharmaceutical manufacturing: Customized enzyme development for specific pharmaceutical processes, leading to more efficient and sustainable manufacturing. Revenue is not broken out publicly. Competitors include companies offering similar enzyme engineering services and traditional chemical synthesis methods.

Market Dynamics

industry overview logo Industry Overview

The enzyme engineering and biocatalysis market is growing due to increasing demand for sustainable manufacturing processes and advanced life science tools. Key trends include the adoption of biocatalysis in pharmaceuticals and the use of enzymes in NGS workflows.

Positioning

Codexis is a leader in enzyme engineering with a strong technology platform. Its competitive advantage lies in its ability to design and optimize enzymes for specific applications with high performance.

Total Addressable Market (TAM)

The estimated TAM for enzyme engineering and biocatalysis is in the billions of dollars. Codexis is well-positioned to capture a significant share of this market through its innovative enzyme solutions and collaborations with leading companies.

Upturn SWOT Analysis

Strengths

  • Proprietary CodeEvolveru00ae technology platform
  • Strong R&D capabilities in enzyme engineering
  • Established partnerships with leading companies
  • Focus on sustainable manufacturing solutions

Weaknesses

  • Reliance on partnerships for revenue
  • Competition from larger companies with more resources
  • Long development cycles for new enzymes
  • Potential regulatory hurdles for enzyme-based products

Opportunities

  • Expanding applications of enzymes in pharmaceuticals and other industries
  • Growing demand for sustainable manufacturing processes
  • Increasing adoption of NGS technologies
  • Potential for new partnerships and collaborations

Threats

  • Competition from companies with similar technologies
  • Technological advancements that could render current enzyme solutions obsolete
  • Changes in regulatory requirements
  • Economic downturn that could reduce demand for enzyme-based products

Competitors and Market Share

competitor logo Key Competitors

  • TMO
  • ILMN
  • QGEN
  • DSM.AS
  • NOVO.CO

Competitive Landscape

Codexis has a strong technology platform, but faces competition from larger companies with more resources. Its competitive advantage lies in its ability to develop customized enzyme solutions with high performance.

Major Acquisitions

Verdant Chem Group

  • Year: 2022
  • Acquisition Price (USD millions): 74
  • Strategic Rationale: Expanded Codexis's access to a broader range of biocatalysis technology and expertise and the revenue stream of the company's specialty chemical intermediates products.

Growth Trajectory and Initiatives

Historical Growth: Codexis's growth has been driven by the increasing adoption of its enzyme engineering solutions in various industries.

Future Projections: Analyst estimates for Codexis's future growth should be sourced independently from financial news providers.

Recent Initiatives: Recent strategic initiatives may include new partnerships, product launches, and expansions into new markets.

Summary

Codexis is a solid enzyme engineering company with a compelling technology platform and strategic partnerships. Its growth is tied to the expanding market for sustainable manufacturing and advanced life science tools. Challenges include competition and the reliance on partnerships. Its success will hinge on continued innovation and effective commercialization.

Peer Comparison

Sources and Disclaimers

Data Sources:

  • Company filings, SEC filings, financial news outlets, market research reports

Disclaimers:

This analysis is for informational purposes only and does not constitute financial advice. Invest at your own risk.

Upturn AI SummarizationUpturn AI Summarization AI Summarization is directionally correct and might not be accurate.

Upturn AI SummarizationUpturn AI Summarization Summarized information shown could be a few years old and not current.

Upturn AI SummarizationUpturn AI Summarization Fundamental Rating based on AI could be based on old data.

Upturn AI SummarizationUpturn AI Summarization AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.

About Codexis Inc

Exchange NASDAQ
Headquaters Redwood City, CA, United States
IPO Launch date 2010-04-22
President, CEO & Chairman Dr. Stephen George Dilly MBBS, Ph.D.
Sector Healthcare
Industry Biotechnology
Full time employees 188
Full time employees 188

Codexis, Inc. provides enzymatic solutions for therapeutics manufacturing, leveraging its proprietary CodeEvolver technology platform to discover, develop, and enhance novel enzymes in the United States, Canada, Latin America, Europe, the Middle East, Africa, Australia, New Zealand, Southeast Asia, and China. The company develops its proprietary ECO Synthesis manufacturing platform to enable the scaled manufacture of RNAi therapeutics through an enzymatic route. It has a license agreement with Aldevron LLC and Pfizer Inc. The company was incorporated in 2002 and is headquartered in Redwood City, California.