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Compass Pathways Plc (CMPS)

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Upturn Advisory Summary
11/14/2025: CMPS (1-star) is a SELL. SELL since 5 days. Simulated Profits (-13.42%). Updated daily EoD!
1 Year Target Price $16.8
1 Year Target Price $16.8
| 7 | Strong Buy |
| 4 | Buy |
| 0 | Hold |
| 0 | Sell |
| 0 | Strong Sell |
Analysis of Past Performance
Type Stock | Historic Profit -62.69% | Avg. Invested days 30 | Today’s Advisory SELL |
Upturn Star Rating ![]() | Upturn Advisory Performance | Stock Returns Performance |
Key Highlights
Company Size Small-Cap Stock | Market Capitalization 507.93M USD | Price to earnings Ratio - | 1Y Target Price 16.8 |
Price to earnings Ratio - | 1Y Target Price 16.8 | ||
Volume (30-day avg) 11 | Beta 1.94 | 52 Weeks Range 2.25 - 7.08 | Updated Date 11/16/2025 |
52 Weeks Range 2.25 - 7.08 | Updated Date 11/16/2025 | ||
Dividends yield (FY) - | Basic EPS (TTM) -2.72 |
Earnings Date
Report Date 2025-10-30 | When - | Estimate -0.3955 | Actual -0.3836 |
Profitability
Profit Margin - | Operating Margin (TTM) - |
Management Effectiveness
Return on Assets (TTM) -38.43% | Return on Equity (TTM) -205.81% |
Valuation
Trailing PE - | Forward PE - | Enterprise Value 349015714 | Price to Sales(TTM) - |
Enterprise Value 349015714 | Price to Sales(TTM) - | ||
Enterprise Value to Revenue - | Enterprise Value to EBITDA -3.51 | Shares Outstanding 96017044 | Shares Floating 59710119 |
Shares Outstanding 96017044 | Shares Floating 59710119 | ||
Percent Insiders 12.12 | Percent Institutions 59.54 |
Upturn AI SWOT
Compass Pathways Plc

Company Overview
History and Background
Compass Pathways Plc was founded in 2016 and is focused on accelerating patient access to evidence-based innovation in mental health. It is pioneering the development of psilocybin therapy for treatment-resistant depression (TRD) and other mental health disorders.
Core Business Areas
- Psilocybin Therapy Development: Researching and developing COMP360, a proprietary formulation of synthetic psilocybin, in conjunction with psychological support, for mental health conditions.
- Clinical Trials and Research: Conducting clinical trials to evaluate the safety and efficacy of COMP360 for TRD and other mental health indications, as well as other innovative therapies.
- Digital Therapies: Exploration and potential development of digital tools and platforms to support mental health treatment.
Leadership and Structure
The leadership team includes Kabir Nath (CEO), Guy Goodwin (Chief Medical Officer). The company has a board of directors with expertise in drug development, finance, and mental health care.
Top Products and Market Share
Key Offerings
- COMP360: A proprietary formulation of synthetic psilocybin being developed for treatment-resistant depression. Currently, there is no direct market share data as the product is still in clinical trials. Competitors include other companies developing psychedelic-assisted therapies, such as GH Research, Cybin, Atai Life Sciences.
Market Dynamics
Industry Overview
The mental health market is substantial and growing, driven by increased awareness, unmet needs, and innovation in treatment options. The psychedelic-assisted therapy market is emerging, with significant interest from investors and pharmaceutical companies.
Positioning
Compass Pathways is a leading company in the psychedelic-assisted therapy space, particularly in the development of psilocybin therapy for TRD. Its competitive advantages include its first-mover advantage, extensive clinical trial data, and intellectual property portfolio.
Total Addressable Market (TAM)
The TAM for TRD treatment is estimated to be several billion dollars globally. Compass Pathways is positioned to capture a significant share of this market if COMP360 is approved and adopted.
Upturn SWOT Analysis
Strengths
- First-mover advantage in psilocybin therapy
- Extensive clinical trial data for COMP360
- Strong intellectual property portfolio
- Experienced leadership team
- Strong cash position
Weaknesses
- Reliance on regulatory approval of COMP360
- High cash burn rate
- Uncertainty surrounding market acceptance of psychedelic therapies
- Potential for competition from other companies
- Limited revenue generation at this stage
Opportunities
- Expansion of COMP360 to other mental health indications
- Partnerships with pharmaceutical companies and healthcare providers
- Development of digital tools and platforms to support mental health treatment
- Increased awareness and acceptance of psychedelic therapies
- Favorable regulatory changes
Threats
- Regulatory hurdles and delays
- Competition from other companies in the psychedelic space
- Negative publicity or safety concerns related to psilocybin
- Lack of reimbursement for psychedelic therapies
- Ethical concerns surrounding the use of psychedelics
Competitors and Market Share
Key Competitors
- GHRS
- CMPS
- MNMD
- ATAI
Competitive Landscape
Compass Pathways is a leading player in the psychedelic-assisted therapy space, but faces increasing competition from other companies. Compass Pathways has a headstart but needs regulatory approval to maintain position.
Growth Trajectory and Initiatives
Historical Growth: Historical growth is limited due to the company's development stage.
Future Projections: Future growth depends on the successful development and commercialization of COMP360 and other therapies. Analyst estimates vary widely.
Recent Initiatives: Recent initiatives include advancing clinical trials for COMP360, expanding research into other mental health indications, and exploring partnerships with pharmaceutical companies.
Summary
Compass Pathways is a leading company in the emerging psychedelic-assisted therapy market, with a strong first-mover advantage in the development of psilocybin therapy for TRD. However, the company faces significant risks related to regulatory approval, competition, and market acceptance. The company's strong cash position provides a buffer, but it needs to manage its cash burn rate carefully. Success hinges on clinical trial success and regulatory approval.
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Sources and Disclaimers
Data Sources:
- Company filings, investor presentations, press releases, analyst reports
Disclaimers:
The information provided is for informational purposes only and does not constitute financial advice. Investment decisions should be based on individual research and consultation with a qualified financial advisor.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About Compass Pathways Plc
Exchange NASDAQ | Headquaters - | ||
IPO Launch date 2020-09-18 | CEO & Director Mr. Kabir Kumar Nath M.A., M.B.A. | ||
Sector Healthcare | Industry Medical Care Facilities | Full time employees 166 | Website https://compasspathways.com |
Full time employees 166 | Website https://compasspathways.com | ||
COMPASS Pathways plc operates as a biotechnology company that focuses on mental health in the United Kingdom and the United States. It develops COMP360, a psilocybin therapy, which is in Phase III clinical trial for the treatment of treatment-resistant depression; and is in Phase II clinical trial for treating post-traumatic stress disorder and anorexia nervosa. The company was formerly known as COMPASS Rx Limited and changed its name to COMPASS Pathways plc in August 2020. The company was incorporated in 2020 and is headquartered in London, the United Kingdom.

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