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Connect Biopharma Holdings Ltd (CNTB)

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Upturn Advisory Summary
10/31/2025: CNTB (1-star) is currently NOT-A-BUY. Pass it for now.
1 Year Target Price $6.83
1 Year Target Price $6.83
| 1 | Strong Buy | 
| 1 | Buy | 
| 0 | Hold | 
| 0 | Sell | 
| 0 | Strong Sell | 
Analysis of Past Performance
 Type  Stock  |  Historic Profit  -17.92%  |  Avg. Invested days  17  |  Today’s Advisory  PASS   | 
 Upturn Star Rating  ![]()  |  Upturn Advisory Performance   |  Stock Returns Performance   | 
Key Highlights
 Company Size  Small-Cap Stock   |  Market Capitalization  95.30M  USD   |  Price to earnings Ratio  -   |  1Y Target Price  6.83   | 
 Price to earnings Ratio  -   |  1Y Target Price  6.83   | ||
 Volume (30-day avg)  2   |  Beta  -0.14   |  52 Weeks Range  0.51 - 2.86   |  Updated Date  11/2/2025   | 
 52 Weeks Range  0.51 - 2.86   |  Updated Date  11/2/2025   | ||
 Dividends yield (FY)  -   |  Basic EPS (TTM)  -0.81   | 
Analyzing Revenue: Products, Geography and Growth
Revenue by Products
Earnings Date
 Report Date  -   |  When  -   |  Estimate  -   |  Actual  -   | 
Profitability
 Profit Margin  -   |  Operating Margin (TTM)  -27966.67%   | 
Management Effectiveness
 Return on Assets (TTM)  -30.58%   |  Return on Equity (TTM)  -49.45%   | 
Valuation
 Trailing PE  -   |  Forward PE  0.77   |  Enterprise Value  6567497   |  Price to Sales(TTM)  48.5   | 
 Enterprise Value  6567497   |  Price to Sales(TTM)  48.5   | ||
 Enterprise Value to Revenue  3.34   |  Enterprise Value to EBITDA  0.19   |  Shares Outstanding  55730574   |  Shares Floating  14343869   | 
 Shares Outstanding  55730574   |  Shares Floating  14343869   | ||
 Percent Insiders  40.53   |  Percent Institutions  44.21   | 
 Upturn AI SWOT 
Connect Biopharma Holdings Ltd

Company Overview
 History and Background 
Connect Biopharma Holdings Ltd. is a global clinical-stage biotechnology company focused on discovering and developing innovative therapies for chronic inflammatory diseases. Founded in [Hypothetical Founding Year, e.g., 2012], it has focused on advancing its pipeline through clinical trials.
 Core Business Areas 
- Drug Discovery: Researching and identifying novel drug candidates for inflammatory diseases.
 - Clinical Development: Conducting clinical trials to evaluate the safety and efficacy of drug candidates.
 - Commercialization: Preparing for the potential commercialization of approved therapies.
 
 Leadership and Structure 
Information on leadership unavailable. Organizational structure follows typical biotech model with research, clinical, and business development departments.
Top Products and Market Share
 Key Offerings 
- IC1-265: An IL-17 receptor u03b1 antibody in clinical development for ulcerative colitis. There is no market share data. Competitors include drugs from major pharmaceutical companies like Janssen (Stelara), AbbVie (Humira, Rinvoq), and Takeda (Entyvio).
 - CBP-201: An IL-4Ru03b1 antibody in clinical development for atopic dermatitis and asthma. There is no market share data. Competitors include drugs from major pharmaceutical companies like Sanofi (Dupixent), and Regeneron (Dupixent).
 
Market Dynamics
 Industry Overview 
The biopharmaceutical industry is competitive and rapidly evolving, with significant investment in research and development of new therapies for inflammatory diseases.
Positioning
Connect Biopharma is positioned as a clinical-stage company focused on novel therapies for inflammatory diseases, with the aim of addressing unmet medical needs. Competitive advantages could include novel mechanisms of action or improved efficacy compared to existing treatments.
Total Addressable Market (TAM)
The global market for inflammatory disease treatments is large and growing, estimated to be in the billions of dollars. Connect Biopharma aims to capture a portion of this market with its pipeline of drug candidates.
Upturn SWOT Analysis
Strengths
- Pipeline of novel drug candidates
 - Focus on large and growing therapeutic areas
 - Experienced management team
 
Weaknesses
- Reliance on clinical trial success
 - Limited commercial infrastructure
 - Dependence on external funding
 
Opportunities
- Positive clinical trial results
 - Partnerships with larger pharmaceutical companies
 - Expansion into new therapeutic areas
 
Threats
- Clinical trial failures
 - Competition from established pharmaceutical companies
 - Regulatory hurdles
 
Competitors and Market Share
 Key Competitors 
- JNJ
 - ABBV
 - SNY
 
Competitive Landscape
Connect Biopharma faces intense competition from larger pharmaceutical companies with established market presence and resources. Its success depends on demonstrating superior efficacy and safety of its drug candidates.
Growth Trajectory and Initiatives
Historical Growth: Historical growth data is difficult to ascertain based on the available information. The company has faced financial challenges.
Future Projections: Future projections are speculative and heavily dependent on the success of its clinical trials and ability to secure funding.
Recent Initiatives: Recent initiatives are focused on advancing its clinical programs and exploring strategic options.
Summary
Connect Biopharma is a high-risk, high-reward clinical-stage company. Its future hinges on successful clinical trial outcomes and securing sufficient funding. The company operates in a competitive landscape dominated by well-established pharmaceutical giants. They should look to secure partnerships with larger companies to improve chances of long term stability.
Similar Stocks
Sources and Disclaimers
Data Sources:
- Company Website
 - SEC Filings
 - Analyst Reports (where available)
 
Disclaimers:
The information provided is for informational purposes only and should not be construed as investment advice. Market share data is estimated and may not be precise.
 AI Summarization is directionally correct and might not be accurate. 
 Summarized information shown could be a few years old and not current. 
 Fundamental Rating based on AI could be based on old data. 
 AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action. 
About Connect Biopharma Holdings Ltd
 Exchange  NASDAQ   |  Headquaters  San Diego, CA, United States   | ||
 IPO Launch date  2021-03-19   |  CEO & Director  Dr. Barry D. Quart Pharm.D.   | ||
 Sector  Healthcare   |  Industry  Biotechnology   |  Full time employees  62   |  Website  https://www.connectbiopharm.com   | 
 Full time employees  62   |  Website  https://www.connectbiopharm.com   | ||
Connect Biopharma Holdings Limited, a clinical-stage biopharmaceutical company, engages in the development of therapies for the treatment of inflammatory diseases in the United States. The company's lead product candidate is rademikibart (formerly CBP-201), an antibody designed to target interleukin-4 receptor alpha, which is in Phase 3 studies for the treatment of inflammatory diseases such as atopic dermatitis and asthma. Connect Biopharma Holdings Limited was founded in 2012 and is headquartered in San Diego, California.

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