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Corvus Pharmaceuticals Inc (CRVS)

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Upturn Advisory Summary
01/09/2026: CRVS (4-star) is currently NOT-A-BUY. Pass it for now.
1 Year Target Price $15.33
1 Year Target Price $15.33
| 5 | Strong Buy |
| 1 | Buy |
| 0 | Hold |
| 0 | Sell |
| 0 | Strong Sell |
Analysis of Past Performance
Type Stock | Historic Profit 1375.24% | Avg. Invested days 37 | Today’s Advisory PASS |
Upturn Star Rating ![]() | Upturn Advisory Performance | Stock Returns Performance |
Key Highlights
Company Size Small-Cap Stock | Market Capitalization 516.80M USD | Price to earnings Ratio - | 1Y Target Price 15.33 |
Price to earnings Ratio - | 1Y Target Price 15.33 | ||
Volume (30-day avg) 6 | Beta 0.69 | 52 Weeks Range 2.54 - 9.60 | Updated Date 01/9/2026 |
52 Weeks Range 2.54 - 9.60 | Updated Date 01/9/2026 | ||
Dividends yield (FY) - | Basic EPS (TTM) -0.54 |
Earnings Date
Report Date - | When - | Estimate - | Actual - |
Profitability
Profit Margin - | Operating Margin (TTM) - |
Management Effectiveness
Return on Assets (TTM) -34.87% | Return on Equity (TTM) -35.82% |
Valuation
Trailing PE - | Forward PE - | Enterprise Value 452120554 | Price to Sales(TTM) - |
Enterprise Value 452120554 | Price to Sales(TTM) - | ||
Enterprise Value to Revenue - | Enterprise Value to EBITDA 0.36 | Shares Outstanding 74681872 | Shares Floating 58112205 |
Shares Outstanding 74681872 | Shares Floating 58112205 | ||
Percent Insiders 3.95 | Percent Institutions 57.41 |
Upturn AI SWOT
Corvus Pharmaceuticals Inc

Company Overview
History and Background
Corvus Pharmaceuticals Inc. was founded in 2014 by Dr. Richard A. Miller and Dr. Peter Van Vlasselaer. The company is a clinical-stage biopharmaceutical company focused on developing and commercializing novel cancer treatments and infectious disease therapies. Its evolution has been marked by the progression of its lead drug candidates through various clinical trial phases and strategic collaborations.
Core Business Areas
- Oncology: Development of small molecule drugs targeting cancer pathways, with a focus on immune-oncology and cancer metabolism.
- Infectious Diseases: Exploration of novel therapeutics for viral and bacterial infections.
Leadership and Structure
Corvus Pharmaceuticals Inc. is led by a management team with extensive experience in drug development and biopharmaceutical management. The organizational structure is typical for a clinical-stage biopharmaceutical company, with specialized departments for research and development, clinical operations, regulatory affairs, and business development.
Top Products and Market Share
Key Offerings
- CRV418 (Adenosine Receptor Antagonist): CRV418 is a selective antagonist of the adenosine A2A receptor, designed to enhance the anti-tumor immune response. It is currently in clinical trials for various solid tumors. Competitors in the adenosine receptor antagonist space include companies developing similar molecules. Market share data is not yet applicable as the product is in clinical development.
- CRV662 (ITK Inhibitor): CRV662 is an inhibitor of inducible T cell kinase (ITK), intended to modulate T cell function. It is being investigated for autoimmune diseases and certain cancers. Competitors include other companies developing ITK inhibitors. Market share data is not yet applicable as the product is in clinical development.
- CRV701 (MTV Vaccine): CRV701 is a candidate vaccine targeting multiple tumor virus (MTV) antigens, aimed at stimulating an immune response against virus-associated cancers. Competitors include other companies developing cancer vaccines and immunotherapies. Market share data is not yet applicable as the product is in clinical development.
Market Dynamics
Industry Overview
The biopharmaceutical industry, particularly the oncology and infectious disease sectors, is characterized by rapid innovation, significant R&D investment, and a complex regulatory environment. The market is driven by unmet medical needs, advancements in scientific understanding of diseases, and the potential for high returns on successful drug development.
Positioning
Corvus Pharmaceuticals Inc. is positioned as a clinical-stage biopharmaceutical company with a pipeline of novel drug candidates. Its competitive advantage lies in its scientific approach, targeting pathways with potential for significant therapeutic impact, and its focus on areas with substantial unmet needs.
Total Addressable Market (TAM)
The TAM for oncology therapeutics is in the hundreds of billions of dollars globally, with significant growth expected. The TAM for infectious disease therapeutics is also substantial. Corvus Pharmaceuticals Inc. is positioned to address specific segments within these large markets with its targeted therapies, but its current market penetration is negligible due to its stage of development.
Upturn SWOT Analysis
Strengths
- Experienced management and scientific team.
- Pipeline of novel drug candidates targeting significant unmet medical needs.
- Focus on innovative therapeutic approaches (e.g., immune-oncology, adenosine receptor antagonism).
Weaknesses
- Clinical-stage company with no approved products, leading to significant financial risk.
- Dependence on successful clinical trial outcomes and regulatory approvals.
- Limited financial resources compared to larger pharmaceutical companies.
- Need for substantial future funding.
Opportunities
- Potential for significant breakthroughs in cancer and infectious disease treatment.
- Strategic partnerships and collaborations with larger pharmaceutical companies.
- Expansion into new therapeutic indications.
- Growth in the overall biopharmaceutical market.
Threats
- Failure of clinical trials.
- Regulatory hurdles and delays.
- Intense competition from established and emerging biopharmaceutical companies.
- Changes in healthcare policy and reimbursement.
- Patent expirations of competing therapies.
Competitors and Market Share
Key Competitors
- Merck & Co., Inc. (MRK)
- Bristol Myers Squibb Company (BMY)
- Pfizer Inc. (PFE)
- Roche Holding AG (RHHBY)
Competitive Landscape
Corvus Pharmaceuticals Inc. faces intense competition from large pharmaceutical companies with established oncology and infectious disease portfolios, as well as other emerging biotechs. Its advantage lies in its potentially novel mechanisms of action and targeted approach. However, it lacks the scale, commercialization infrastructure, and diversified revenue streams of larger competitors.
Growth Trajectory and Initiatives
Historical Growth: Corvus Pharmaceuticals Inc.'s growth has been primarily characterized by scientific and clinical progress, moving its drug candidates through successive stages of development. Financial growth is characterized by increasing investment in R&D and efforts to secure funding.
Future Projections: Future growth projections for Corvus Pharmaceuticals Inc. are heavily contingent on the successful progression and regulatory approval of its lead drug candidates. Analyst estimates, if available, would focus on potential future revenue streams upon market entry. Without approved products, precise future revenue projections are highly uncertain.
Recent Initiatives: Recent initiatives likely include advancing ongoing clinical trials, exploring new therapeutic applications for existing candidates, and securing funding through equity offerings or strategic partnerships.
Summary
Corvus Pharmaceuticals Inc. is a clinical-stage biopharmaceutical company with a promising pipeline in oncology and infectious diseases, leveraging innovative therapeutic approaches. Its strengths lie in its scientific focus and experienced team. However, it faces significant weaknesses due to its lack of approved products, substantial financial risks, and dependence on clinical trial success. Opportunities exist in market growth and strategic partnerships, but threats from competition, regulatory hurdles, and clinical trial failures are considerable. Careful monitoring of its clinical progress and funding status is crucial.
Similar Stocks
Sources and Disclaimers
Data Sources:
- Company investor relations website
- SEC filings (10-K, 10-Q)
- Financial news and analysis platforms (e.g., Yahoo Finance, Bloomberg - for general industry and competitor information, not direct Corvus financial data which is limited)
- Biopharmaceutical industry reports
Disclaimers:
This JSON output is generated based on publicly available information and AI analysis. It is not financial advice and should not be used as the sole basis for investment decisions. All financial data for clinical-stage companies is subject to significant change and uncertainty. Market share data for clinical-stage products is indicative and not based on actual sales. Readers should conduct their own due diligence.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About Corvus Pharmaceuticals Inc
Exchange NASDAQ | Headquaters South San Francisco, CA, United States | ||
IPO Launch date 2016-03-23 | Co-Founder, President, CEO & Chairman of the Board Dr. Richard A. Miller M.D. | ||
Sector Healthcare | Industry Biotechnology | Full time employees 31 | Website https://www.corvuspharma.com |
Full time employees 31 | Website https://www.corvuspharma.com | ||
Corvus Pharmaceuticals, Inc., a clinical stage biopharmaceutical company, engages in the development of product candidates that precisely target proteins that are critical to immune cell maturation and function in the United States. The company's lead product candidate is soquelitinib (CPI-818), a selective covalent inhibitor of interleukin 2 inducible T cell kinase (ITK), which is in a multi-center Phase 1/1b clinical trial for the treatment of peripheral T cell atopic dermatitis, asthma, psoriasis, and fibrotic diseases. It also developing ciforadenant (CPI-444), an oral small molecule antagonist of the A2A receptor that is in Phase 2 clinical trial for the treatment of metastatic renal cell cancer; and mupadolimab (CPI-006), a humanized monoclonal antibody, which is in Phase 1b clinical trial for the treatment of non-small cell lung cancer. It has a license agreement with Monash University to research, develop, and commercialize certain antibodies directed to CXCR2 for the treatment of human diseases; and Vernalis (R&D) Limited to develop, manufacture, and commercialize products containing certain adenosine receptor antagonists, including ciforadenant, as well as strategic collaboration with Angel Pharmaceuticals Co. Ltd. for the development and commercialization of mupadolimab. Corvus Pharmaceuticals, Inc. was incorporated in 2014 and is based in South San Francisco, California.

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