Cytosorbents Crp logo

Cytosorbents Crp(CTSO)

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ADVISORIES YOU CAN VERIFY
QUALITY SIGNAL
1-STAR RATING
PASS
LAST CLOSE
$4.02
09/28/2026
(24-hour delay)

Advisory History & Simulated Performance *

*as per simulation (see disclosures)
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Upturn Advisory & Investor View for CTSO

09/28/2026: CTSO (1-star) is currently NOT-A-BUY. Pass it for now.

Cytosorbents is a medical technology company focused on blood purification, with its primary product, CytoSorb, used to remove inflammatory mediators in critical care settings. The company's main strength lies in its specialized hemadsorption technology, which has achieved a foothold in European markets. Its long-term investment story centers on potential US regulatory approval, which could significantly expand its market access. However, investors must weigh this against financial risks, including a lack of profitability and reliance on a narrow product portfolio. The stock may best suit growth-oriented investors with a high tolerance for risk, while market participants should closely monitor clinical trial updates and FDA engagement.

How to Read the Upturn Advisory

The Upturn Star Rating and the current BUY, SELL, or PASS advisory are generated by Upturn’s AI advisory engine based on proprietary signal analysis, price behavior, advisory history, and historical signal performance.

Company fundamentals, valuation, risks, and news provide supporting context about the business.

Investor Fit

Investor styleFitWhy
Growth investorMixed fitThe growth narrative is highly dependent on binary outcomes like FDA approvals.
Momentum investorMixed fitThe stock often exhibits high volatility surrounding clinical trial updates.
Value investorWeak fitThe company is not currently profitable, making traditional valuation metrics difficult to apply.
Dividend investorWeak fitThe company does not pay dividends.
Low-risk investorWeak fitHigh clinical and execution risks lead to significant price volatility.

Risk Profile

Risk factorLevelWhy it matters
Price volatilityHighClinical-stage biotech stocks are sensitive to news, causing rapid price swings.
Valuation riskMedium / highLack of profitability makes the stock price highly sensitive to future growth assumptions.
Competition risk (Major MedTech)Medium / highLarger players can exert pricing pressure or bundle competing technologies.
Business qualityMediumThe firm relies on a single technology platform which limits diversification.
Dividend incomeLow / noneInvestors should not expect income from this investment.
Execution riskHighSuccess depends on complex regulatory pathways and hospital adoption cycles.

Price Behavior

Steep Decline
PRICE PATH

Steep Decline

The stock price has dropped sharply with strong downward pressure.

Extreme Price Shocks
PRICE STABILITY

Extreme Price Shocks

The stock has experienced exceptionally large and disruptive price movements during the period.

Analysis of Past Performance

Type Stock
Historic Profit -73.79%
Avg. Invested days 17
Today’s Advisory PASS
Upturn Advisory Rating upturn star rating icon
Upturn Advisory Performance Upturn Advisory Performance icon 1.0
Stock Returns Performance Upturn Returns Performance icon 1.0
Upturn Profits based on simulation icon Profits based on simulation
Upturn last close icon Last Close 09/28/2026

Upturn Scorecard

Upturn Star Rating

★★★★★
CTSO receives a 3-star rating based on the available scored pillars. The rating is constrained by weak unit economics, and weak price momentum.

Company Fundamentals

★★★★★
CTSO has moderate overall fundamentals (3 stars), with soft financial health, solid growth momentum, and solid ownership. In FY2025 versus FY2024, strong earnings growth (+60.4%) is partially offset by weak cash generation (FCF margin -33.8%), moderate revenue growth (+4.1%), weak profitability (net margin -22.1%).

Financial Health Rating

★★★★★
CTSO's financial health is soft, with the relatively strongest area being moderate liquidity, including working-capital and asset support (WC/assets 24.7%). Cash strength is soft (2 stars), which helps explain the 2-star overall score.

Growth Momentum Score

★★★★★
Earnings growth is CTSO's strongest growth driver at +60.4% FY2025 versus FY2024 (strong, 5 stars). By comparison, free-cash-flow growth (+14.8%, solid) is also solid, while revenue growth (+4.1%, moderate) holds the profile back, so recent growth is not broad-based across the business.

Ownership

★★★★★
Institutional ownership is 25.8% and approximately 85.1% of outstanding shares are publicly tradable, supporting liquidity and institutional participation. Insider ownership of 15.99% supports management-shareholder alignment.

Top 5 Institutional Investors

Avenir Corporation 8.30%
Vanguard Capital Management, LLC 2.99%
Neuberger Berman Group LLC 2.68%
CM Management, LLC 2.35%
Skylands Capital, LLC 1.93%

Unit Economics (Per $1K Revenue)

★★★★★
CTSO generates approximately $715 of gross profit, $-384 of operating income, and $-338 of free cash flow for every $1,000 of revenue. Based on FY2025 results. Operating losses and cash burn explain the 1-star rating, with weak cash conversion and weak capital efficiency.

Economic Dimensions

★★★★★
Effective Tax Rate: 4.66%

Quantitative Style Profile

★★★★★
CTSO has a liquid profile. Weak momentum is the primary drawback, while elevated volatility.

Style Classification

Quality Focused

Value-OrientedHigh VolatilitySmall / Mid Cap RiskHighly Liquid / Institution-Friendly

Key Highlights

Company Size Small-Cap Stock
Market Capitalization 12.67M USD
Price to earnings Ratio -
1Y Target Price 47.5
Price to earnings Ratio -
1Y Target Price 47.5
Volume (30-day avg) 20.6K shares
Beta 1.34
52 Weeks Range 3.94 - 20.40
Updated Date 09/28/2026
52 Weeks Range 3.94 - 20.40
Updated Date 09/28/2026
Dividends yield (FY) -
Basic EPS (TTM) -5.32

How Company Makes Money

Business areaWhat it includesRetail investor read
Critical CareSales of the CytoSorb hemadsorption cartridge.The company makes money by selling specialized filters used in hospital intensive care units.
Geography: EuropePrimary revenue generation region for current operations.Most current sales occur in European hospitals where the device is currently approved.

Analyzing Revenue: Products, Geography and Growth

Revenue by Products

Product revenue - Year on Year

Revenue by Geography

Geography revenue - Year on Year

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Valuation

Trailing PE -
Forward PE 7.2
Enterprise Value 40.48M
Price to Sales(TTM) 0.34
Enterprise Value 40.48M
Price to Sales(TTM) 0.34
Enterprise Value to Revenue 1.09
Enterprise Value to EBITDA -1.92
Shares Outstanding 3.15M
Shares Floating 2.68M
Shares Outstanding 3.15M
Shares Floating 2.68M
Percent Insiders 15.99
Percent Institutions 25.78

Icon representing Upturn AI-generated SWOT analysis summary Upturn AI Summary

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Financial Metrics

🧭 Investment Snapshot

Total Revenue (Scale)

Information icon Total money earned from selling products or services before any costs. It is needed to understand the scale of the business and its ability to generate income.

Net Income (Profit)

Information icon Final profit after all expenses, interest, and taxes are deducted. It is needed to determine the overall profitability available to shareholders.

Free Cash Flow (Cash Strength)

Information icon Cash remaining after operating activities and capital expenditures, showing cash available for growth. It is needed to evaluate the company’s ability to invest, pay dividends, or reduce debt.

📈 Growth & Strength

Operating Income (Core Profit)

Information icon Profit from core operations after deducting all operating expenses. It is needed to measure how efficiently the company runs its primary business activities.

EBITDA (Cash Earnings)

Information icon Earnings before interest, taxes, depreciation, and amortization, indicating operating cash potential. It is needed to compare operating performance across companies without accounting or financing differences.

Gross Profit (Unit Profitability)

Information icon Revenue minus cost of revenue, showing profit after direct production costs. It is needed to evaluate core business profitability before overhead expenses.

🛡️ Financial Safety

Cash (Liquidity Buffer)

Information icon Total cash and cash equivalents on hand. It is needed to evaluate immediate liquidity and financial flexibility.

Total Debt (Leverage Risk)

Information icon Total debt including both short-term and long-term components. It is needed to assess the company’s leverage and financial risk.

Net Working Capital (Short-Term Health)

Information icon Current assets minus current liabilities, indicating short-term liquidity strength. It is needed to assess whether the company can meet its short-term obligations.

🧱 Balance Sheet Strength

Stockholder Equity (Net Worth)

Information icon Total equity value held by shareholders. It is needed to understand the net worth of the company from the owners’ perspective.

Total Assets (Asset Base)

Information icon The full value of everything the company owns, including cash, inventory, equipment, and investments. It is needed to understand the resource base used to generate revenue.

Income Before Tax (Pre-Tax Earnings)

Information icon Income before provision for income taxes. It is needed to analyze profitability independent of tax structures.

⚙️ Cost & Drag Factors

Cost of Revenue (Production Cost)

Information icon Direct costs required to produce and deliver the products or services sold. It is needed to assess efficiency in production and service delivery.

Total Operating Expenses (Operating Cost)

Information icon Indirect costs of running the business such as salaries, marketing, and administration. It is needed to understand how much it costs to sustain ongoing business operations.

Income Tax Expense (Tax Drag)

Information icon Amount of taxes paid or payable to the government. It is needed to evaluate the impact of taxation on overall profitability.

About Cytosorbents Crp

Exchange NASDAQ
Headquarters Princeton, NJ, United States
IPO Launch date 2013-11-07
CEO & Director Dr. Phillip P. Chan M.D., Ph.D.
Sector Healthcare
Industry Medical Devices
Full time employees 129
Full time employees 129

Cytosorbents Corporation engages in the research, development, and commercialization of medical devices with its blood purification technology platform in the United States, Germany, and internationally. Its flagship product, CytoSorb, is an extracorporeal blood purification cartridge to reduce cytokine storms in common critical illnesses, bilirubin in liver failure, myoglobin in trauma and critical illnesses, and inflammatory mediators and blood thinners in cardiac surgery applications, as well as to remove antithrombotic drugs and inflammatory mediators in cardiothoracic surgery applications. The company also develops DrugSorb-ATR antithrombotic removal system, an investigational device to reduce the severity of perioperative bleeding in high-risk surgery due to blood thinning drugs; ECOS-300CY to reduce cytokines and other inflammatory mediators when used in an ex vivo organ perfusion system; VetResQ, a broad-spectrum blood purification adsorber for the treatment of septic shock, toxic shock syndrome, toxin-mediated diseases, pancreatitis, trauma, liver failure, heat stroke, and lung injury in animals; and PuriFi, an advanced hemoperfusion pump for blood purification therapies. In addition, it develops HemoDefend-BGA, a blood purification technology platform to reduce anti-A and anti-B antibodies in plasma and whole blood. The company was formerly known as MedaSorb Technologies Corporation and changed its name to Cytosorbents Corporation in May 2010. Cytosorbents Corporation was founded in 1997 and is headquartered in Princeton, New Jersey.