Cadrenal Therapeutics, Inc. Common Stock logo

Cadrenal Therapeutics, Inc. Common Stock(CVKD)

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ADVISORIES YOU CAN VERIFY
QUALITY SIGNAL
1-STAR RATING
PASS
LAST CLOSE
$1.15
09/25/2026
(24-hour delay)

Advisory History & Simulated Performance *

*as per simulation (see disclosures)
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Upturn Advisory & Investor View for CVKD

09/25/2026: CVKD (1-star) is currently NOT-A-BUY. Pass it for now.

Cadrenal Therapeutics, Inc. is a pre-revenue, clinical-stage biotechnology company developing tecarfarin, a therapy targeting cardiovascular issues in patients with end-stage renal disease. Its primary strength lies in its specialized focus on an underserved patient population, potentially offering a unique metabolic alternative to current anticoagulants. The investment story is centered on the potential success of tecarfarin in clinical trials and its subsequent regulatory approval. However, the company faces significant execution and financial risks, as it currently lacks revenue and relies entirely on research success. This stock best suits growth-oriented investors with high risk tolerance who are capable of monitoring clinical milestones and regulatory progress in the biotechnology sector.

How to Read the Upturn Advisory

The Upturn Star Rating and the current BUY, SELL, or PASS advisory are generated by Upturn’s AI advisory engine based on proprietary signal analysis, price behavior, advisory history, and historical signal performance.

Company fundamentals, valuation, risks, and news provide supporting context about the business.

Investor Fit

Investor styleFitWhy
Growth investorMixed fitThe company offers high-risk, high-reward exposure to drug development but lacks the revenue growth track record of established firms.
Momentum investorWeak fitMomentum is generally tied to positive clinical data releases or regulatory catalysts rather than sustained trading trends.
Value investorWeak fitAs a pre-revenue company, traditional valuation metrics are not applicable, making it unsuitable for value-based investment strategies.
Dividend investorWeak fitThe company does not generate revenue or profit and pays no dividends.
Low-risk investorWeak fitThe speculative nature of clinical-stage biotechnology poses high volatility and capital risk.

Risk Profile

Risk factorLevelWhy it matters
Price volatilityHighThe stock is highly sensitive to news regarding clinical trial outcomes and financing events.
Valuation riskHighValuation is based on the perceived future potential of tecarfarin rather than existing fundamentals.
Competition risk (Direct Oral Anticoagulants)HighEntrenched competitors dominate the market, making market penetration difficult for any new entrant.
Business qualityMediumThe company is a single-asset developer, which concentrates risk on the outcome of one product.
Dividend incomeLow / noneInvestors should expect no income, as cash is reinvested into development.
Execution riskHighSuccessfully managing clinical trials and obtaining regulatory approval is a complex, multi-year endeavor.

Price Behavior

Steep Decline
PRICE PATH

Steep Decline

The stock price has dropped sharply with strong downward pressure.

Highly Choppy
PRICE STABILITY

Highly Choppy

The stock has experienced frequent, large price swings that make its near-term movement less predictable.

Analysis of Past Performance

Type Stock
Historic Profit 55.53%
Avg. Invested days 43
Today’s Advisory PASS
Upturn Advisory Rating upturn star rating icon
Upturn Advisory Performance Upturn Advisory Performance icon 3.0
Stock Returns Performance Upturn Returns Performance icon 3.0
Upturn Profits based on simulation icon Profits based on simulation
Upturn last close icon Last Close 09/25/2026

Upturn Scorecard

Upturn Star Rating

★★★★★
CVKD receives a 3-star rating, supported by solid analyst coverage. The rating is constrained by weak unit economics, and weak price momentum.

Company Fundamentals

★★★★★
CVKD has moderate overall fundamentals (3 stars), with moderate financial health, soft growth momentum, and solid ownership. In FY2025 versus FY2024, growth and ownership metrics are mixed: negative earnings growth (-24.3%), soft cash generation (FCF margin 0.0%), slightly negative revenue growth (+0.0%).

Financial Health Rating

★★★★★
CVKD's financial health is supported by strong efficiency, including operating-expense and cost-of-revenue discipline (opex 0.0% of revenue). Profitability is weak (1 stars), which helps explain the 3-star overall score.

Growth Momentum Score

★★★★★
CVKD's growth profile is soft, with the least-weak measure being revenue growth at +0.0% FY2025 versus FY2024. By comparison, while earnings growth (-24.3%, negative) and free-cash-flow growth (-71.1%, negative) hold the profile back, so recent growth is not broad-based across the business.

Ownership

★★★★★
Institutional ownership is 9.7% and approximately 88.1% of outstanding shares are publicly tradable, supporting liquidity and institutional participation. Insider ownership of 11.93% supports management-shareholder alignment.

Top 5 Institutional Investors

Vanguard Capital Management, LLC 1.27%
Geode Capital Management, LLC 0.61%
Vanguard Fiduciary Trust Co 0.23%
JPMorgan Chase & Co 0.21%
BlackRock Inc 0.15%

Unit Economics (Per $1K Revenue)

★★★★★
CVKD generates approximately $0 of gross profit, $-0 of operating income, and $-0 of free cash flow for every $1,000 of revenue. Based on FY2025 results. Strong margins, cash conversion, and capital efficiency support the rating.

Economic Dimensions

★★★★★
Effective Tax Rate: 0.00%

Quantitative Style Profile

★★★★★
CVKD has a liquid profile. Weak momentum is the primary drawback, while elevated volatility.

Style Classification

Quality Focused

Value-OrientedHigh VolatilitySmall / Mid Cap RiskHighly Liquid / Institution-Friendly

Key Highlights

Company Size Small-Cap Stock
Market Capitalization 4.10M USD
Price to earnings Ratio -
1Y Target Price 14
Price to earnings Ratio -
1Y Target Price 14
Volume (30-day avg) 843.1K shares
Beta 1.84
52 Weeks Range 1.00 - 14.64
Updated Date 09/25/2026
52 Weeks Range 1.00 - 14.64
Updated Date 09/25/2026
Dividends yield (FY) -
Basic EPS (TTM) -4.88

How Company Makes Money

Business areaWhat it includesRetail investor read
Drug DevelopmentClinical trial development for tecarfarin.The company earns no money currently and is solely focused on proving that its drug works.
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Valuation

Trailing PE -
Forward PE -
Enterprise Value 347.55K
Price to Sales(TTM) -
Enterprise Value 347.55K
Price to Sales(TTM) -
Enterprise Value to Revenue -
Enterprise Value to EBITDA 0.21
Shares Outstanding 3.57M
Shares Floating 3.14M
Shares Outstanding 3.57M
Shares Floating 3.14M
Percent Insiders 11.93
Percent Institutions 9.75

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Financial Metrics

🧭 Investment Snapshot

Total Revenue (Scale)

Information icon Total money earned from selling products or services before any costs. It is needed to understand the scale of the business and its ability to generate income.

Net Income (Profit)

Information icon Final profit after all expenses, interest, and taxes are deducted. It is needed to determine the overall profitability available to shareholders.

Free Cash Flow (Cash Strength)

Information icon Cash remaining after operating activities and capital expenditures, showing cash available for growth. It is needed to evaluate the company’s ability to invest, pay dividends, or reduce debt.

📈 Growth & Strength

Operating Income (Core Profit)

Information icon Profit from core operations after deducting all operating expenses. It is needed to measure how efficiently the company runs its primary business activities.

EBITDA (Cash Earnings)

Information icon Earnings before interest, taxes, depreciation, and amortization, indicating operating cash potential. It is needed to compare operating performance across companies without accounting or financing differences.

Gross Profit (Unit Profitability)

Information icon Revenue minus cost of revenue, showing profit after direct production costs. It is needed to evaluate core business profitability before overhead expenses.

🛡️ Financial Safety

Cash (Liquidity Buffer)

Information icon Total cash and cash equivalents on hand. It is needed to evaluate immediate liquidity and financial flexibility.

Total Debt (Leverage Risk)

Information icon Total debt including both short-term and long-term components. It is needed to assess the company’s leverage and financial risk.

Net Working Capital (Short-Term Health)

Information icon Current assets minus current liabilities, indicating short-term liquidity strength. It is needed to assess whether the company can meet its short-term obligations.

🧱 Balance Sheet Strength

Stockholder Equity (Net Worth)

Information icon Total equity value held by shareholders. It is needed to understand the net worth of the company from the owners’ perspective.

Total Assets (Asset Base)

Information icon The full value of everything the company owns, including cash, inventory, equipment, and investments. It is needed to understand the resource base used to generate revenue.

Income Before Tax (Pre-Tax Earnings)

Information icon Income before provision for income taxes. It is needed to analyze profitability independent of tax structures.

⚙️ Cost & Drag Factors

Cost of Revenue (Production Cost)

Information icon Direct costs required to produce and deliver the products or services sold. It is needed to assess efficiency in production and service delivery.

Total Operating Expenses (Operating Cost)

Information icon Indirect costs of running the business such as salaries, marketing, and administration. It is needed to understand how much it costs to sustain ongoing business operations.

Income Tax Expense (Tax Drag)

Information icon Amount of taxes paid or payable to the government. It is needed to evaluate the impact of taxation on overall profitability.

About Cadrenal Therapeutics, Inc. Common Stock

Exchange NASDAQ
Headquarters Ponte Vedra, FL, United States
IPO Launch date 2023-01-20
Chairman & CEO Mr. Quang X. Pham
Sector Healthcare
Industry Biotechnology
Full time employees 5
Full time employees 5

Cadrenal Therapeutics, Inc. operates as a late-stage biopharmaceutical company that develops novel therapies for life-threatening immune and thrombotic conditions. The company is developing Tecarfarin, an oral vitamin K antagonist that is in Phase 3 clinical trial designed to prevent heart attacks, strokes, and deaths due to blood clots in patients requiring chronic anticoagulation, such as patients with left ventricular assist devices, end-stage kidney disease, and atrial fibrillation; CAD-1005, a first-in-class 12-LOX inhibitor for the treatment of heparin-induced thrombocytopenia, a deadly immune-mediated thrombotic disorder that has completed Phase 2 clinical trial; and Frunexian, a parenteral clinical-stage factor XIa inhibitor designed for use in acute hospital settings that has completed Phase 1 clinical trial. It has a collaboration agreement with Abbott Global Enterprises Limited to evaluate the efficacy and safety of Tecarfarin in patients with a left-ventricular assist device. The company was incorporated in 2022 and is headquartered in Ponte Vedra, Florida.