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United Therapeutics Corporation(UTHR)

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EXPLORE ADVISORIES AND THEIR HISTORY
QUALITY SIGNAL RECENCY
4-STAR RATING
STRONG BUY
BUY for 17 days
PROFIT SINCE LAST BUY
+1.09% ▲
LAST CLOSE
$591.17
11/13/2026
(24-hour delay)

Advisory History & Simulated Performance *

*as per simulation (see disclosures)
  • ALL
  • 1Y
  • 1M
  • 1W
  • BUY Advisory
  • SELL Advisory (Profit)
  • SELL Advisory (Loss)
  • Profit
  • Loss
  • PASS (Skip)
Upturn Stock price based on last close iconStock price based on last close
Simulated performance—not actual client returns. Excludes advisory subscription fees, trading commissions, and taxes, which would reduce returns. Results depend on calculation assumptions and do not guarantee future outcomes. See Disclosures for full methodology, assumptions, and limitations.

Advisory Performance History (Simulated)Advisory Performance History info

Simulated performance—not actual client returns. Excludes advisory subscription fees, trading commissions, and taxes, which would reduce returns. Results depend on calculation assumptions and do not guarantee future outcomes. See Disclosures for full methodology, assumptions, and limitations.

Upturn Advisory & Investor View for UTHR

11/13/2026: UTHR (4-star) is a STRONG-BUY. BUY for 17 days. Simulated Profits (1.09%). Updated daily EoD!

United Therapeutics Corporation is a specialized biotechnology company focused on treating pulmonary arterial hypertension and pioneering organ manufacturing technologies. Its primary strengths lie in its successful delivery of innovative treprostinil-based therapies and a robust, founder-led business model. The investment story centers on the commercial success of products like Tyvaso and the long-term potential of its xenotransplantation pipeline. Key risks include heavy reliance on a narrow product portfolio, intensifying generic competition, and regulatory uncertainties. This stock typically suits growth-oriented investors with a high risk tolerance, and observers should monitor upcoming clinical trial results and patent litigation closely.

How to Read the Upturn Advisory

The Upturn Star Rating and the current BUY, SELL, or PASS advisory are generated by Upturn’s AI advisory engine based on proprietary signal analysis, price behavior, advisory history, and historical signal performance.

Company fundamentals, valuation, risks, and news provide supporting context about the business.

Investor Fit

Investor styleFitWhy
Growth investorStrong fitThe company's focus on innovative therapies and organ manufacturing provides a strong narrative for long-term capital appreciation.
Momentum investorMixed fitMomentum is often linked to clinical trial news and regulatory updates, requiring a positive trend signal.
Value investorMixed fitThe valuation reflects high growth expectations, which may not align with traditional value metrics.
Dividend investorWeak fitThe company does not pay a dividend as it prioritizes reinvestment into its R&D pipeline.
Low-risk investorWeak fitAs a biotechnology firm subject to clinical and regulatory risks, the stock exhibits higher volatility than stable blue-chip companies.

Risk Profile

Risk factorLevelWhy it matters
Price volatilityMedium / highBiotech stocks are highly sensitive to clinical data results and regulatory decisions.
Valuation riskMediumGrowth expectations are high, making the stock sensitive to earnings misses.
Competition risk (PAH market)HighGeneric entry and large pharma competitors put pressure on pricing and market share.
Business qualityStrongThe company has established a stable, profitable core business with a clear mission.
Dividend incomeLow / noneInvestors should not expect income from this equity investment.
Execution riskMediumSuccessfully bringing complex organ manufacturing to market involves significant operational challenges.

Key Highlights

Company Size Large-Cap Stock
Market Capitalization 25.18B USD
Price to earnings Ratio 22.32
1Y Target Price 687.14
Price to earnings Ratio 22.32
1Y Target Price 687.14
Volume (30-day avg) 636.1K shares
Beta 0.48
52 Weeks Range 455.63 - 614.23
Updated Date 11/13/2026
52 Weeks Range 455.63 - 614.23
Updated Date 11/13/2026
Dividends yield (FY) -
Basic EPS (TTM) 26.49

Sector & Industry Intelligence

Sector

Healthcare

Bullish
Sentiment
Strong Bullish
Momentum
Momentum Steady
BUY participation
62.6%
Active BUY / eligible
72 / 115
30-Day BUY Count Change
+35
Market state
Strong Bullish

The number of qualifying BUY stocks has remained relatively stable.

Industry

Drug Manufacturers - Specialty & Generic

BUY participation
66.7%
Active BUY / eligible
8 / 12
30-Day BUY Count Change
+3

Sector signal summarizes BUY breadth conditions for the sector. It does not override this stock’s BUY, SELL, or PASS advisory.

Price Behavior

Flat / Range-Bound
PRICE PATH

Flat / Range-Bound

The stock price has been trading within a narrow range with minimal directional movement.

Moderately Choppy
PRICE STABILITY

Moderately Choppy

The stock has experienced noticeable price swings while retaining some directional structure.

Analysis of Past Performance

Type Stock
Historic Profit 93.75%
Avg. Invested days 49
Today’s Advisory Strong Buy
Upturn Advisory Rating upturn star rating icon
Upturn Advisory Performance Upturn Advisory Performance icon 4.0
Stock Returns Performance Upturn Returns Performance icon 4.0
Upturn Profits based on simulation icon Profits based on simulation
Upturn last close icon Last Close 11/13/2026

Upturn Scorecard

Upturn Star Rating

★★★★★
UTHR receives a 4-star rating, supported by strong unit economics, solid company fundamentals, solid quantitative characteristics, and solid analyst coverage. The rating is constrained by weak price momentum.

Company Fundamentals

★★★★★
UTHR has solid overall fundamentals (4 stars), with strong financial health, solid growth momentum, and solid ownership. In FY2025 versus FY2024, solid earnings growth (+11.7%) and strong cash generation (FCF margin 32.7%) are partially offset by modest insider ownership of 2.02%.

Financial Health Rating

★★★★★
UTHR's financial health is supported by strong cash strength, including free-cash-flow generation of $1.0B (32.7% of revenue). Operating efficiency is solid (4 stars), which helps explain the 5-star overall score.

Growth Momentum Score

★★★★★
Earnings growth is UTHR's strongest growth driver at +11.7% FY2025 versus FY2024 (solid, 4 stars). By comparison, revenue growth (+10.6%, solid) is also solid, while free-cash-flow growth (-3.7%, slightly negative) holds the profile back, so recent growth is not broad-based across the business.

Ownership

★★★★★
Institutional ownership is 101.7% and approximately 91.4% of outstanding shares are publicly tradable, supporting liquidity and institutional participation. Insider ownership of 2.02% provides only moderate management-shareholder alignment.

Top 5 Institutional Investors

BlackRock Inc 12.43%
venBio Select Advisor LLC 6.52%
Vanguard Portfolio Management, LLC 4.51%
Vanguard Capital Management, LLC 4.50%
State Street Corp 4.46%

Unit Economics (Per $1K Revenue)

★★★★★
UTHR generates approximately $879 of gross profit, $477 of operating income, and $327 of free cash flow for every $1,000 of revenue. Based on FY2025 results. Strong margins, cash conversion, and capital efficiency support the rating.

Economic Dimensions

★★★★★
Effective Tax Rate: 22.12%

Quantitative Style Profile

★★★★★
UTHR has a high-quality, large-cap, liquid, relatively low-volatility profile. Weak momentum is the primary drawback, while valuation that is moderately attractive rather than deeply discounted.

Style Classification

Quality Focused

Quality TiltLow VolatilityLarge / Mega Cap StabilityShort Squeeze RiskHighly Liquid / Institution-Friendly

How Company Makes Money

Business areaWhat it includesRetail investor read
Commercialized PAH TherapiesTyvaso, Remodulin, and Orenitram sales.The company generates the vast majority of its revenue from specialty drugs used to treat pulmonary arterial hypertension.
Organ Transplantation TechnologyResearch and development in ex-vivo lung perfusion and xenotransplantation.This is a long-term R&D investment area designed to solve organ shortages and currently does not contribute significant revenue.

Analyzing Revenue: Products, Geography and Growth

Revenue by Products

Product revenue - Year on Year

Revenue by Geography

Geography revenue - Year on Year

Earnings Date

Report Date 2026-11-04
When Before Market
Estimate 5.85
Actual 5.71

Profitability

Profit Margin 38.61%
Operating Margin (TTM) 39.38%

Management Effectiveness

Return on Assets (TTM) 10.91%
Return on Equity (TTM) 19.13%

Valuation

Trailing PE 22.32
Forward PE 18.8
Enterprise Value 22.15B
Price to Sales(TTM) 7.9
Enterprise Value 22.15B
Price to Sales(TTM) 7.9
Enterprise Value to Revenue 6.95
Enterprise Value to EBITDA 13.71
Shares Outstanding 42.59M
Shares Floating 38.91M
Shares Outstanding 42.59M
Shares Floating 38.91M
Percent Insiders 2.02
Percent Institutions 101.71

Financial Metrics

🧭 Investment Snapshot

Total Revenue (Scale)

Information icon Total money earned from selling products or services before any costs. It is needed to understand the scale of the business and its ability to generate income.

Net Income (Profit)

Information icon Final profit after all expenses, interest, and taxes are deducted. It is needed to determine the overall profitability available to shareholders.

Free Cash Flow (Cash Strength)

Information icon Cash remaining after operating activities and capital expenditures, showing cash available for growth. It is needed to evaluate the company’s ability to invest, pay dividends, or reduce debt.

📈 Growth & Strength

Operating Income (Core Profit)

Information icon Profit from core operations after deducting all operating expenses. It is needed to measure how efficiently the company runs its primary business activities.

EBITDA (Cash Earnings)

Information icon Earnings before interest, taxes, depreciation, and amortization, indicating operating cash potential. It is needed to compare operating performance across companies without accounting or financing differences.

Gross Profit (Unit Profitability)

Information icon Revenue minus cost of revenue, showing profit after direct production costs. It is needed to evaluate core business profitability before overhead expenses.

🛡️ Financial Safety

Cash (Liquidity Buffer)

Information icon Total cash and cash equivalents on hand. It is needed to evaluate immediate liquidity and financial flexibility.

Total Debt (Leverage Risk)

Information icon Total debt including both short-term and long-term components. It is needed to assess the company’s leverage and financial risk.

Net Working Capital (Short-Term Health)

Information icon Current assets minus current liabilities, indicating short-term liquidity strength. It is needed to assess whether the company can meet its short-term obligations.

🧱 Balance Sheet Strength

Stockholder Equity (Net Worth)

Information icon Total equity value held by shareholders. It is needed to understand the net worth of the company from the owners’ perspective.

Total Assets (Asset Base)

Information icon The full value of everything the company owns, including cash, inventory, equipment, and investments. It is needed to understand the resource base used to generate revenue.

Income Before Tax (Pre-Tax Earnings)

Information icon Income before provision for income taxes. It is needed to analyze profitability independent of tax structures.

⚙️ Cost & Drag Factors

Cost of Revenue (Production Cost)

Information icon Direct costs required to produce and deliver the products or services sold. It is needed to assess efficiency in production and service delivery.

Total Operating Expenses (Operating Cost)

Information icon Indirect costs of running the business such as salaries, marketing, and administration. It is needed to understand how much it costs to sustain ongoing business operations.

Income Tax Expense (Tax Drag)

Information icon Amount of taxes paid or payable to the government. It is needed to evaluate the impact of taxation on overall profitability.

Form CRS provides a relationship summary of our automated advisory services, flat subscription fees, and conflicts of interest. Form ADV Part 2A brochure contains complete details on services, billing, and disclosures. If any summary differs from our current regulatory filings, the filed Form ADV controls.