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Precision BioSciences Inc(DTIL)
Advisory History & Simulated Performance *
*as per simulation (see disclosures)- ALL
- 1Y
- 1M
- 1W
- BUY Advisory
- SELL Advisory (Profit)
- SELL Advisory (Loss)
- Profit
- Loss
- PASS (Skip)
Stock price based on last close Advisory Performance History (Simulated)
Upturn Advisory & Investor View for DTIL
10/16/2026: DTIL (1-star) is currently NOT-A-BUY. Pass it for now.
Precision BioSciences is an early-stage biotechnology company that utilizes its proprietary ARCUS genome-editing platform to develop in vivo therapies for challenging genetic and infectious diseases. Its primary strength lies in the unique, versatile nature of the ARCUS enzyme, which is supported by strategic partnerships with major pharmaceutical entities. While the firm offers significant growth potential through its clinical-stage pipeline, investors face high risks related to product development, financial sustainability, and intense competition from well-funded CRISPR-based firms. It is best suited for risk-tolerant investors looking for long-term exposure to the gene-editing sector. Key developments to monitor include clinical trial outcomes and the acquisition of new licensing partnerships.
How to Read the Upturn Advisory
The Upturn Star Rating and the current BUY, SELL, or PASS advisory are generated by Upturn’s AI advisory engine based on proprietary signal analysis, price behavior, advisory history, and historical signal performance.
Company fundamentals, valuation, risks, and news provide supporting context about the business.
Investor Fit
| Investor style | Fit | Why |
|---|---|---|
| Growth investor | Mixed fit | The company offers exposure to high-growth gene editing technology but remains in a speculative, pre-commercial stage. |
| Momentum investor | Mixed fit | Stock price movement is often event-driven, requiring a positive upturn signal to match momentum strategies. |
| Value investor | Weak fit | As a pre-revenue biotechnology company, traditional value metrics like P/E ratios are not applicable. |
| Dividend investor | Weak fit | The company does not pay dividends and reinvests all capital into research. |
| Low-risk investor | Weak fit | High clinical, regulatory, and financial risks make this unsuitable for risk-averse portfolios. |
Risk Profile
| Risk factor | Level | Why it matters |
|---|---|---|
| Price volatility | High | Clinical trial results and partnership news can cause sudden and sharp stock price swings. |
| Valuation risk | High | Valuations are highly speculative and based on the potential success of unproven therapeutic candidates. |
| Competition risk (CRISPR technology) | High | Established players with better-funded CRISPR platforms could outpace or obsolete the ARCUS technology. |
| Business quality | Medium | While the technology is innovative, the company lacks a commercial-stage product engine. |
| Dividend income | Low / none | There is no income generation for shareholders. |
| Execution risk | High | Success depends entirely on the technical and clinical validation of ARCUS-based therapies. |
Price Behavior
Rolling Over
The price momentum is slowing down and beginning to turn downward.
Choppy
The stock has experienced frequent reversals and pronounced short-term price swings.
Analysis of Past Performance
Type Stock | Historic Profit -64.46% | Avg. Invested days 20 | Today’s Advisory PASS |
Upturn Advisory Rating  | Upturn Advisory Performance  1.0 | Stock Returns Performance  1.0 |
| Profits based on simulation | Last Close 10/16/2026 |
Upturn Scorecard
Upturn Star Rating 
Company Fundamentals
Financial Health Rating
Growth Momentum Score
Ownership
Top 5 Institutional Investors
Unit Economics (Per $1K Revenue)
Economic Dimensions
Quantitative Style Profile
Style Classification
Quality Focused
Key Highlights
Company Size Small-Cap Stock | Market Capitalization 159.26M USD | Price to earnings Ratio - | 1Y Target Price 29.4 |
Price to earnings Ratio - | 1Y Target Price 29.4 | ||
Volume (30-day avg) 257.3K shares | Beta 1.27 | 52 Weeks Range 3.53 - 9.62 | Updated Date 10/18/2026 |
52 Weeks Range 3.53 - 9.62 | Updated Date 10/18/2026 | ||
Dividends yield (FY) - | Basic EPS (TTM) -1.35 |
How Company Makes Money
| Business area | What it includes | Retail investor read |
|---|---|---|
| Collaboration and Licensing Revenue | Upfront payments, R&D funding, milestone payments, and potential royalties from partnerships. | The company generates cash by leasing its gene-editing technology to larger drug companies. |
Analyzing Revenue: Products, Geography and Growth
Revenue by Products
Product revenue - Year on Year
Valuation
Trailing PE - | Forward PE 11.78 | Enterprise Value 116.10M | Price to Sales(TTM) 3.53 |
Enterprise Value 116.10M | Price to Sales(TTM) 3.53 | ||
Enterprise Value to Revenue 2.58 | Enterprise Value to EBITDA -0.27 | Shares Outstanding 27.60M | Shares Floating 25.45M |
Shares Outstanding 27.60M | Shares Floating 25.45M | ||
Percent Insiders 8.04 | Percent Institutions 68.7 |
Financial Metrics
🧭 Investment Snapshot
Total Revenue (Scale)
Total money earned from selling products or services before any costs. It is needed to understand the scale of the business and its ability to generate income.
Net Income (Profit)
Final profit after all expenses, interest, and taxes are deducted. It is needed to determine the overall profitability available to shareholders.
Free Cash Flow (Cash Strength)
Cash remaining after operating activities and capital expenditures, showing cash available for growth. It is needed to evaluate the company’s ability to invest, pay dividends, or reduce debt.
📈 Growth & Strength
Operating Income (Core Profit)
Profit from core operations after deducting all operating expenses. It is needed to measure how efficiently the company runs its primary business activities.
EBITDA (Cash Earnings)
Earnings before interest, taxes, depreciation, and amortization, indicating operating cash potential. It is needed to compare operating performance across companies without accounting or financing differences.
Gross Profit (Unit Profitability)
Revenue minus cost of revenue, showing profit after direct production costs. It is needed to evaluate core business profitability before overhead expenses.
🛡️ Financial Safety
Cash (Liquidity Buffer)
Total cash and cash equivalents on hand. It is needed to evaluate immediate liquidity and financial flexibility.
Total Debt (Leverage Risk)
Total debt including both short-term and long-term components. It is needed to assess the company’s leverage and financial risk.
Net Working Capital (Short-Term Health)
Current assets minus current liabilities, indicating short-term liquidity strength. It is needed to assess whether the company can meet its short-term obligations.
🧱 Balance Sheet Strength
Stockholder Equity (Net Worth)
Total equity value held by shareholders. It is needed to understand the net worth of the company from the owners’ perspective.
Total Assets (Asset Base)
The full value of everything the company owns, including cash, inventory, equipment, and investments. It is needed to understand the resource base used to generate revenue.
Income Before Tax (Pre-Tax Earnings)
Income before provision for income taxes. It is needed to analyze profitability independent of tax structures.
⚙️ Cost & Drag Factors
Cost of Revenue (Production Cost)
Direct costs required to produce and deliver the products or services sold. It is needed to assess efficiency in production and service delivery.
Total Operating Expenses (Operating Cost)
Indirect costs of running the business such as salaries, marketing, and administration. It is needed to understand how much it costs to sustain ongoing business operations.
Income Tax Expense (Tax Drag)
Amount of taxes paid or payable to the government. It is needed to evaluate the impact of taxation on overall profitability.
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