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Dyne Therapeutics Inc (DYN)



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Upturn Advisory Summary
08/29/2025: DYN (3-star) is a STRONG-BUY. BUY since 14 days. Profits (16.09%). Updated daily EoD!
1 Year Target Price $35.35
1 Year Target Price $35.35
7 | Strong Buy |
6 | Buy |
1 | Hold |
0 | Sell |
0 | Strong Sell |
Analysis of Past Performance
Type Stock | Historic Profit 127.02% | Avg. Invested days 47 | Today’s Advisory Regular Buy |
Upturn Star Rating ![]() ![]() | Upturn Advisory Performance ![]() | Stock Returns Performance ![]() |
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Key Highlights
Company Size Small-Cap Stock | Market Capitalization 1.96B USD | Price to earnings Ratio - | 1Y Target Price 35.35 |
Price to earnings Ratio - | 1Y Target Price 35.35 | ||
Volume (30-day avg) 14 | Beta 1.08 | 52 Weeks Range 6.36 - 37.08 | Updated Date 08/29/2025 |
52 Weeks Range 6.36 - 37.08 | Updated Date 08/29/2025 | ||
Dividends yield (FY) - | Basic EPS (TTM) -3.88 |
Earnings Date
Report Date - | When - | Estimate - | Actual - |
Profitability
Profit Margin - | Operating Margin (TTM) - |
Management Effectiveness
Return on Assets (TTM) -35.45% | Return on Equity (TTM) -61.32% |
Valuation
Trailing PE - | Forward PE - | Enterprise Value 1393278425 | Price to Sales(TTM) - |
Enterprise Value 1393278425 | Price to Sales(TTM) - | ||
Enterprise Value to Revenue - | Enterprise Value to EBITDA -8.87 | Shares Outstanding 142264000 | Shares Floating 122664065 |
Shares Outstanding 142264000 | Shares Floating 122664065 | ||
Percent Insiders 0.49 | Percent Institutions 95.55 |
Upturn AI SWOT
Dyne Therapeutics Inc

Company Overview
History and Background
Dyne Therapeutics, Inc. (NASDAQ: DYN) was founded in 2017. It is a clinical-stage biotechnology company focused on developing therapies for serious muscle diseases. The company has built a proprietary FORCE platform designed to deliver oligonucleotides to muscle tissue.
Core Business Areas
- Muscle Disease Therapies: Dyne focuses on developing therapies for myotonic dystrophy type 1 (DM1), Duchenne muscular dystrophy (DMD), and facioscapulohumeral muscular dystrophy (FSHD).
- FORCE Platform: The FORCE platform is a key technology for developing targeted oligonucleotide therapies. It enables efficient delivery of therapies to muscle tissue.
Leadership and Structure
Farhad Khosravi, M.D., Ph.D., is the President and CEO. The company has a board of directors with expertise in biotechnology and drug development. Dyne operates with a typical biotechnology company structure, including research and development, clinical operations, and business development departments.
Top Products and Market Share
Key Offerings
- DMT1: DYNE-101: DYNE-101 is being developed for the treatment of myotonic dystrophy type 1 (DM1). It is currently in clinical trials (Phase 1/2). The market opportunity is significant given the lack of effective treatments for DM1. Competitors include companies developing gene therapies and other oligonucleotide-based therapies for DM1.
- DMD: DYNE-251: DYNE-251 is in development for Duchenne muscular dystrophy (DMD) amenable to exon 51 skipping. It is also in clinical trials. Competitors in the DMD space include Sarepta Therapeutics (SRPT) and Vertex Pharmaceuticals (VRTX).
- FSHD: DYNE-301: DYNE-301 is in development for Facioscapulohumeral Muscular Dystrophy (FSHD). Competitors are trying to target the same area as DYNE.
Market Dynamics
Industry Overview
The industry is characterized by intense research and development, high regulatory hurdles, and a growing demand for treatments for rare and genetic diseases. Significant advancements are being made in gene therapy, RNA therapeutics, and targeted drug delivery systems.
Positioning
Dyne Therapeutics is positioning itself as a leader in developing targeted oligonucleotide therapies for muscle diseases using its FORCE platform. Its competitive advantage lies in its ability to efficiently deliver therapies to muscle tissue.
Total Addressable Market (TAM)
The combined TAM for DM1, DMD, and FSHD is estimated to be several billion dollars. Dyne is positioned to capture a significant portion of this market if its therapies are successful.
Upturn SWOT Analysis
Strengths
- Proprietary FORCE platform for targeted drug delivery
- Pipeline of therapies for serious muscle diseases
- Strong management team with expertise in drug development
- Solid financial position
Weaknesses
- Clinical trial risks and uncertainties
- Dependence on successful development of pipeline products
- Competition from larger pharmaceutical companies
Opportunities
- Expanding the FORCE platform to other disease areas
- Securing regulatory approvals for pipeline products
- Partnering with larger pharmaceutical companies
- Acquiring complementary technologies or companies
Threats
- Clinical trial failures
- Regulatory setbacks
- Competition from other companies developing muscle disease therapies
- Economic downturn impacting funding for biotechnology companies
Competitors and Market Share
Key Competitors
- SRPT
- VRTX
- IONS
Competitive Landscape
Dyne's advantages lie in its FORCE platform and focus on targeted muscle delivery. Disadvantages include being a smaller company with less resources compared to larger pharmaceutical firms such as Sarepta Therapeutics and Vertex Pharmaceuticals.
Growth Trajectory and Initiatives
Historical Growth: The company's growth has been driven by advancements in its FORCE platform and the progression of its pipeline products through preclinical and clinical development.
Future Projections: Future growth is dependent on successful clinical trial outcomes and regulatory approvals. Analyst estimates vary, but generally project significant revenue growth in the coming years if therapies are approved.
Recent Initiatives: Recent initiatives include advancing DYNE-101, DYNE-251, and DYNE-301 through clinical trials and expanding its FORCE platform.
Summary
Dyne Therapeutics is a clinical-stage biotechnology company with a promising technology platform for delivering therapies to muscle tissue. Its future success hinges on the clinical trial outcomes of its pipeline candidates. While the company faces strong competition, the unmet medical need in muscle diseases provides a significant market opportunity. A key factor for success will be obtaining regulatory approval for its therapies and out-competing SRPT, VRTX, and IONS.
Peer Comparison
Sources and Disclaimers
Data Sources:
- Dyne Therapeutics Investor Relations
- SEC Filings
- Analyst Reports
- Company Press Releases
Disclaimers:
This analysis is for informational purposes only and does not constitute financial advice. Investment decisions should be made based on individual risk tolerance and thorough research.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About Dyne Therapeutics Inc
Exchange NASDAQ | Headquaters Waltham, MA, United States | ||
IPO Launch date 2020-09-17 | CEO, President & Director Mr. John G. Cox M.B.A. | ||
Sector Healthcare | Industry Biotechnology | Full time employees 206 | Website https://www.dyne-tx.com |
Full time employees 206 | Website https://www.dyne-tx.com |
Dyne Therapeutics, Inc., a clinical-stage neuromuscular disease company, focuses on discovering and developing therapeutics for neuromuscular diseases in the United States. It is developing a portfolio of muscle disease therapeutics, including programs in myotonic dystrophy type 1; duchenne muscular dystrophy; facioscapulohumeral dystrophy; and Pompe disease, as well as rare skeletal muscle, and cardiac and metabolic muscle diseases using its FORCE platform that delivers disease-modifying therapeutics. The company was incorporated in 2017 and is headquartered in Waltham, Massachusetts.

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