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DYN logo DYN
Upturn stock rating
DYN logo

Dyne Therapeutics Inc (DYN)

Upturn stock rating
$16.38
Last Close (24-hour delay)
Profit since last BUY11.58%
upturn advisory
Strong Buy
BUY since 7 days
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Upturn Stock info Stock price based on last close
*as per simulation
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Time period over
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Upturn Advisory Summary

10/17/2025: DYN (3-star) is a STRONG-BUY. BUY since 7 days. Simulated Profits (11.58%). Updated daily EoD!

Upturn Star Rating

rating

Moderate Performance

These Stocks/ETFs, based on Upturn Advisory, typically align with the market average, offering steady but unremarkable returns.

Number of Analysts

rating

14 Analysts rated it

Moderately tracked stock, growing coverage, gaining market and investor attention.

1 Year Target Price $34.53

1 Year Target Price $34.53

Analysts Price Target For last 52 week
$34.53 Target price
52w Low $6.36
Current$16.38
52w High $35.68

Analysis of Past Performance

Type Stock
Historic Profit 136.22%
Avg. Invested days 43
Today’s Advisory Strong Buy
Upturn Star Rating upturn star rating icon
Upturn Advisory Performance Upturn Advisory Performance 4.0
Stock Returns Performance Upturn Returns Performance 5.0
Upturn Profits based on simulation Profits based on simulation
Upturn Profits based on simulation Last Close 10/17/2025

Key Highlights

Company Size Mid-Cap Stock
Market Capitalization 2.34B USD
Price to earnings Ratio -
1Y Target Price 34.53
Price to earnings Ratio -
1Y Target Price 34.53
Volume (30-day avg) 14
Beta 1.08
52 Weeks Range 6.36 - 35.68
Updated Date 10/17/2025
52 Weeks Range 6.36 - 35.68
Updated Date 10/17/2025
Dividends yield (FY) -
Basic EPS (TTM) -3.88

Earnings Date

Report Date -
When -
Estimate -
Actual -

Profitability

Profit Margin -
Operating Margin (TTM) -

Management Effectiveness

Return on Assets (TTM) -35.45%
Return on Equity (TTM) -61.32%

Valuation

Trailing PE -
Forward PE -
Enterprise Value 1222561937
Price to Sales(TTM) -
Enterprise Value 1222561937
Price to Sales(TTM) -
Enterprise Value to Revenue -
Enterprise Value to EBITDA -8.87
Shares Outstanding 142263740
Shares Floating 122622808
Shares Outstanding 142263740
Shares Floating 122622808
Percent Insiders 0.5
Percent Institutions 94.69

ai summary icon Upturn AI SWOT

Dyne Therapeutics Inc

stock logo

Company Overview

overview logo History and Background

Dyne Therapeutics, Inc. was founded in 2017. The company focuses on developing therapies for serious muscle diseases using its proprietary FORCE platform.

business area logo Core Business Areas

  • Muscle Disease Therapeutics: Dyne develops targeted therapeutics for various muscle diseases, including myotonic dystrophy type 1 (DM1), Duchenne muscular dystrophy (DMD), and facioscapulohumeral muscular dystrophy (FSHD).

leadership logo Leadership and Structure

Dyne is led by CEO John Crowley. The company has a board of directors and a management team focused on research, development, and clinical operations.

Top Products and Market Share

overview logo Key Offerings

  • DMT-101 (DM1 Program): DMT-101 is Dyne's lead program, targeting myotonic dystrophy type 1 (DM1). It is currently in clinical trials. Market share data is not yet available as it is pre-commercialization. Competitors are focused on symptom management and gene therapy approaches such as those from Avidity Biosciences (RNA targeting therapies).
  • Duchenne Muscular Dystrophy (DMD) Programs: Dyne is developing multiple programs for DMD, including compounds targeting specific exons. Market share is not yet applicable. Competitors include Sarepta Therapeutics (exon skipping) and Solid Biosciences (gene therapy).
  • FSHD Program: Dyne also has a program targeting facioscapulohumeral muscular dystrophy (FSHD). Market share not available, as it is in early stages of development. Competitors are focusing on gene editing such as Fulcrum Therapeutics.

Market Dynamics

industry overview logo Industry Overview

The industry focuses on developing therapies for rare genetic diseases, especially muscle disorders. There's growing interest in targeted therapies and gene editing technologies.

Positioning

Dyne Therapeutics is positioned as a leader in targeted oligonucleotide therapies for muscle diseases. Its FORCE platform offers a competitive advantage in drug delivery and specificity.

Total Addressable Market (TAM)

The total addressable market for muscle disease therapies is estimated to be in the billions of dollars, considering the high unmet need and the high cost of rare disease treatments. Dyne is positioned to capture a significant portion of this market with successful clinical trials and commercialization.

Upturn SWOT Analysis

Strengths

  • Proprietary FORCE platform
  • Strong intellectual property
  • Experienced management team
  • Promising preclinical and clinical data

Weaknesses

  • Dependence on successful clinical trial outcomes
  • High cash burn rate
  • Limited commercial infrastructure
  • Risk of regulatory setbacks

Opportunities

  • Expansion to other muscle diseases
  • Partnerships with larger pharmaceutical companies
  • Accelerated regulatory pathways for rare diseases
  • Positive clinical trial results driving market adoption

Threats

  • Competition from other gene therapy and oligonucleotide companies
  • Clinical trial failures
  • Regulatory hurdles
  • Pricing pressures

Competitors and Market Share

competitor logo Key Competitors

  • SRPT
  • AVDL
  • PTCT

Competitive Landscape

Dyne's advantages lie in its FORCE platform and targeted approach. Disadvantages stem from its early stage of development compared to more established competitors. The above market share data is an estimate for the overall muscle disease therapeutics market.

Growth Trajectory and Initiatives

Historical Growth: Dyne's historical growth has been driven by preclinical and clinical advancements.

Future Projections: Future growth depends on successful clinical trial outcomes and regulatory approvals. Analyst projections are highly variable based on clinical trial readouts.

Recent Initiatives: Dyne's recent initiatives include advancing its clinical programs for DM1 and DMD, as well as expanding its research pipeline.

Summary

Dyne Therapeutics is a promising biotechnology company focused on developing therapies for muscle diseases. Its FORCE platform offers a potential advantage. However, the company faces risks associated with clinical trial outcomes and competition. The company has a high cash burn rate so it needs to secure future sources of funding.

Peer Comparison

Sources and Disclaimers

Data Sources:

  • Dyne Therapeutics Investor Relations
  • SEC Filings
  • Analyst Reports
  • Company Press Releases

Disclaimers:

The information provided is for informational purposes only and should not be considered financial advice. Market share data are estimates based on available information and may not be precise. Investment decisions should be based on individual research and consultation with a financial advisor.

Upturn AI Summarization AI Summarization is directionally correct and might not be accurate.

Upturn AI Summarization Summarized information shown could be a few years old and not current.

Upturn AI Summarization Fundamental Rating based on AI could be based on old data.

Upturn AI Summarization AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.

About Dyne Therapeutics Inc

Exchange NASDAQ
Headquaters Waltham, MA, United States
IPO Launch date 2020-09-17
CEO, President & Director Mr. John G. Cox M.B.A.
Sector Healthcare
Industry Biotechnology
Full time employees 206
Full time employees 206

Dyne Therapeutics, Inc., a clinical-stage neuromuscular disease company, focuses on discovering and developing therapeutics for neuromuscular diseases in the United States. It is developing a portfolio of muscle disease therapeutics, including programs in myotonic dystrophy type 1; duchenne muscular dystrophy; facioscapulohumeral dystrophy; and Pompe disease, as well as rare skeletal muscle, and cardiac and metabolic muscle diseases using its FORCE platform that delivers disease-modifying therapeutics. The company was incorporated in 2017 and is headquartered in Waltham, Massachusetts.