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Edgewise Therapeutics Inc(EWTX)
Advisory History & Simulated Performance *
*as per simulation (see disclosures)- ALL
- 1Y
- 1M
- 1W
- BUY Advisory
- SELL Advisory (Profit)
- SELL Advisory (Loss)
- Profit
- Loss
- PASS (Skip)
Stock price based on last close Advisory Performance History (Simulated)
Upturn Advisory & Investor View for EWTX
11/10/2026: EWTX (2-star) has a low Upturn Star Rating. Not recommended to BUY.
Edgewise Therapeutics is a clinical-stage biotechnology company focused on developing oral small-molecule therapies for rare muscle disorders like Duchenne muscular dystrophy. Its primary strength lies in its specialized scientific approach to treating muscle damage, which offers a potentially convenient alternative to injectable therapies. The investment story centers on the clinical success of its lead candidate, Sevasemten. However, the company faces significant execution and competitive risks, including potential challenges from gene-therapy competitors and the inherent uncertainty of clinical trial outcomes. This stock is best suited for growth-oriented investors with high risk tolerance who are willing to monitor critical clinical trial milestones and regulatory developments.
How to Read the Upturn Advisory
The Upturn Star Rating and the current BUY, SELL, or PASS advisory are generated by Upturn’s AI advisory engine based on proprietary signal analysis, price behavior, advisory history, and historical signal performance.
Company fundamentals, valuation, risks, and news provide supporting context about the business.
Investor Fit
| Investor style | Fit | Why |
|---|---|---|
| Growth investor | Mixed fit | The company offers high growth potential dependent on binary clinical trial outcomes. |
| Momentum investor | Mixed fit | This is a conditional fit based on positive clinical data readouts driving share price upturns. |
| Value investor | Weak fit | As a pre-revenue company, traditional valuation metrics like P/E are not applicable. |
| Dividend investor | Weak fit | The company does not pay dividends and reinvests all capital into research. |
| Low-risk investor | Weak fit | High clinical and financial risk makes this unsuitable for conservative portfolios. |
Risk Profile
| Risk factor | Level | Why it matters |
|---|---|---|
| Price volatility | High | Clinical-stage biotech stocks often experience significant price swings based on trial results. |
| Valuation risk | High | Valuations are speculative and highly dependent on future market share assumptions. |
| Competition risk (Rare Disease Therapies) | Medium / high | Competitors have larger resources and may reach market faster with alternative therapies. |
| Business quality | Medium | The company has strong intellectual property but lacks a commercial track record. |
| Dividend income | Low / none | Investors should expect no income return from this stock. |
| Execution risk | High | The success of the company relies entirely on complex clinical development and regulatory approval. |
Price Behavior
Strong Uptrend
The stock has maintained a strong upward price trend across the last three quarters.
Choppy
The stock has experienced frequent reversals and pronounced short-term price swings.
Analysis of Past Performance
Type Stock | Historic Profit -11.64% | Avg. Invested days 24 | Today’s Advisory Consider higher Upturn Star rating |
Upturn Advisory Rating  | Upturn Advisory Performance  2.0 | Stock Returns Performance  1.0 |
| Profits based on simulation | Last Close 11/10/2026 |
Upturn Scorecard
Upturn Star Rating 
Company Fundamentals
Financial Health Rating
Growth Momentum Score
Ownership
Top 5 Institutional Investors
Unit Economics (Per $1K Revenue)
Economic Dimensions
Quantitative Style Profile
Style Classification
Quality Focused
Key Highlights
Company Size Mid-Cap Stock | Market Capitalization 5.34B USD | Price to earnings Ratio 5.82 | 1Y Target Price 55.42 |
Price to earnings Ratio 5.82 | 1Y Target Price 55.42 | ||
Volume (30-day avg) 1.6M shares | Beta 0.4 | 52 Weeks Range 19.76 - 48.78 | Updated Date 11/10/2026 |
52 Weeks Range 19.76 - 48.78 | Updated Date 11/10/2026 | ||
Dividends yield (FY) - | Basic EPS (TTM) 8.38 |
How Company Makes Money
| Business area | What it includes | Retail investor read |
|---|---|---|
| Drug Development | Clinical trial advancement of proprietary small-molecule candidates. | The company does not currently generate revenue; its value is tied to the potential future success of its clinical pipeline. |
Earnings Date
Report Date 2026-11-04 | When After Market | Estimate -0.55 | Actual 0.84 |
Profitability
Profit Margin - | Operating Margin (TTM) - |
Management Effectiveness
Return on Assets (TTM) -11.54% | Return on Equity (TTM) 92.14% |
Valuation
Trailing PE 5.82 | Forward PE - | Enterprise Value 3.19B | Price to Sales(TTM) - |
Enterprise Value 3.19B | Price to Sales(TTM) - | ||
Enterprise Value to Revenue - | Enterprise Value to EBITDA -2.6 | Shares Outstanding 109.48M | Shares Floating 75.15M |
Shares Outstanding 109.48M | Shares Floating 75.15M | ||
Percent Insiders 0.48 | Percent Institutions 111.74 |
Financial Metrics
🧭 Investment Snapshot
Total Revenue (Scale)
Total money earned from selling products or services before any costs. It is needed to understand the scale of the business and its ability to generate income.
Net Income (Profit)
Final profit after all expenses, interest, and taxes are deducted. It is needed to determine the overall profitability available to shareholders.
Free Cash Flow (Cash Strength)
Cash remaining after operating activities and capital expenditures, showing cash available for growth. It is needed to evaluate the company’s ability to invest, pay dividends, or reduce debt.
📈 Growth & Strength
Operating Income (Core Profit)
Profit from core operations after deducting all operating expenses. It is needed to measure how efficiently the company runs its primary business activities.
EBITDA (Cash Earnings)
Earnings before interest, taxes, depreciation, and amortization, indicating operating cash potential. It is needed to compare operating performance across companies without accounting or financing differences.
Gross Profit (Unit Profitability)
Revenue minus cost of revenue, showing profit after direct production costs. It is needed to evaluate core business profitability before overhead expenses.
🛡️ Financial Safety
Cash (Liquidity Buffer)
Total cash and cash equivalents on hand. It is needed to evaluate immediate liquidity and financial flexibility.
Total Debt (Leverage Risk)
Total debt including both short-term and long-term components. It is needed to assess the company’s leverage and financial risk.
Net Working Capital (Short-Term Health)
Current assets minus current liabilities, indicating short-term liquidity strength. It is needed to assess whether the company can meet its short-term obligations.
🧱 Balance Sheet Strength
Stockholder Equity (Net Worth)
Total equity value held by shareholders. It is needed to understand the net worth of the company from the owners’ perspective.
Total Assets (Asset Base)
The full value of everything the company owns, including cash, inventory, equipment, and investments. It is needed to understand the resource base used to generate revenue.
Income Before Tax (Pre-Tax Earnings)
Income before provision for income taxes. It is needed to analyze profitability independent of tax structures.
⚙️ Cost & Drag Factors
Cost of Revenue (Production Cost)
Direct costs required to produce and deliver the products or services sold. It is needed to assess efficiency in production and service delivery.
Total Operating Expenses (Operating Cost)
Indirect costs of running the business such as salaries, marketing, and administration. It is needed to understand how much it costs to sustain ongoing business operations.
Income Tax Expense (Tax Drag)
Amount of taxes paid or payable to the government. It is needed to evaluate the impact of taxation on overall profitability.
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