Gain Therapeutics Inc logo

Gain Therapeutics Inc(GANX)

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EXPLORE ADVISORIES AND THEIR HISTORY
QUALITY SIGNAL
1-STAR RATING
PASS
LAST CLOSE
$1.64
10/09/2026
(24-hour delay)

Advisory History & Simulated Performance *

*as per simulation (see disclosures)
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  • 1M
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  • BUY Advisory
  • SELL Advisory (Profit)
  • SELL Advisory (Loss)
  • Profit
  • Loss
  • PASS (Skip)
Upturn Stock price based on last close iconStock price based on last close
Simulated performance—not actual client returns. Results depend on calculation assumptions and do not guarantee future outcomes. See Disclosures for methodology, assumptions, and limitations.

Advisory Performance History (Simulated)Advisory Performance History info

Simulated performance—not actual client returns. Results depend on calculation assumptions and do not guarantee future outcomes. See Disclosures for methodology, assumptions, and limitations.

Upturn Advisory & Investor View for GANX

10/09/2026: GANX (1-star) is currently NOT-A-BUY. Pass it for now.

Gain Therapeutics is a clinical-stage biotechnology firm dedicated to creating small-molecule treatments for lysosomal and protein-misfolding diseases. The company's main strength is its proprietary SEE-Tx platform, which enables the discovery of novel therapeutic binding sites. Its primary growth opportunity lies in moving lead candidates like GT-02287 through clinical trials to potential commercialization or strategic licensing. However, the company faces significant risks, including the inherent uncertainty of clinical development, a lack of current revenue, and the need for ongoing capital raises. This stock is best suited for risk-tolerant investors seeking exposure to drug discovery; investors should monitor clinical milestones and potential partnership announcements closely.

How to Read the Upturn Advisory

The Upturn Star Rating and the current BUY, SELL, or PASS advisory are generated by Upturn’s AI advisory engine based on proprietary signal analysis, price behavior, advisory history, and historical signal performance.

Company fundamentals, valuation, risks, and news provide supporting context about the business.

Investor Fit

Investor styleFitWhy
Growth investorMixed fitThe company offers high growth potential linked to R&D milestones, but carries the extreme risk of clinical-stage biotech.
Momentum investorMixed fitMomentum may occur around clinical data releases, but the stock lacks the consistent trend history required for long-term momentum strategies.
Value investorWeak fitAs a non-profitable, early-stage biotech firm, traditional valuation metrics are not applicable.
Dividend investorWeak fitThe company does not pay dividends and reinvests all capital.
Low-risk investorWeak fitThe high volatility and clinical success risks are unsuitable for low-risk portfolios.

Risk Profile

Risk factorLevelWhy it matters
Price volatilityHighClinical trial results can cause significant, rapid share price fluctuations.
Valuation riskHighSpeculative valuations based on future outcomes present significant downside if milestones are missed.
Competition risk (rare disease therapeutics)HighLarger, better-capitalized competitors can out-invest and out-market smaller biotech firms.
Business qualityMediumThe company is early-stage without a commercial franchise or proven revenue stream.
Dividend incomeLow / noneInvestors should expect no income, only speculative capital gain.
Execution riskHighThe complexity of drug development and regulatory approval poses significant operational hurdles.

Price Behavior

Downtrend
PRICE PATH

Downtrend

The stock has experienced a sustained decline in price over recent periods.

Extreme Price Shocks
PRICE STABILITY

Extreme Price Shocks

The stock has experienced exceptionally large and disruptive price movements during the period.

Analysis of Past Performance

Type Stock
Historic Profit -61.05%
Avg. Invested days 24
Today’s Advisory PASS
Upturn Advisory Rating upturn star rating icon
Upturn Advisory Performance Upturn Advisory Performance icon 2.0
Stock Returns Performance Upturn Returns Performance icon 1.0
Upturn Profits based on simulation icon Profits based on simulation
Upturn last close icon Last Close 10/09/2026

Upturn Scorecard

Upturn Star Rating

★★★★★
GANX receives a 3-star rating, supported by solid analyst coverage. The rating is constrained by weak unit economics, and weak price momentum.

Company Fundamentals

★★★★★
GANX has moderate overall fundamentals (3 stars), with moderate financial health, moderate growth momentum, and moderate ownership. In FY2025 versus FY2024, moderate earnings growth (+1.2%) is partially offset by soft cash generation (FCF margin 0.0%), slightly negative revenue growth (+0.0%), soft profitability (net margin 0.0%).

Financial Health Rating

★★★★★
GANX's financial health is supported by strong efficiency, including operating-expense and cost-of-revenue discipline (opex 0.0% of revenue). Profitability is weak (1 stars), which helps explain the 3-star overall score.

Growth Momentum Score

★★★★★
Free-cash-flow growth is GANX's strongest growth driver at +2.3% FY2025 versus FY2024 (moderate, 3 stars). By comparison, while revenue growth (+0.0%, slightly negative) holds the profile back, so recent growth is not broad-based across the business.

Ownership

★★★★★
Institutional ownership is 19.8% (soft) and 97.7% of outstanding shares are publicly tradable (strong). Insider ownership of 2.23% provides only moderate management-shareholder alignment.

Top 5 Institutional Investors

Marshall Wace Asset Management Ltd 4.41%
CAMBRIDGE Invest RESEARCH ADVISORS, INC. 2.61%
Potomac Capital Management, Inc. 2.17%
GSA Capital Partners LLP 1.45%
JONES FINANCIAL COMPANIES LLLP 1.39%

Unit Economics (Per $1K Revenue)

★★★★★
GANX generates approximately $-0 of gross profit, $-0 of operating income, and $-0 of free cash flow for every $1,000 of revenue. Based on FY2025 results. Weak margins explain the 1-star rating, with weak cash conversion and strong capital efficiency.

Economic Dimensions

★★★★★
Effective Tax Rate: -4.46% (Tax Credit)

Quantitative Style Profile

★★★★★
GANX has a liquid, relatively low-volatility profile. Weak momentum is the primary drawback, while soft valuation.

Style Classification

Quality Focused

Low VolatilitySmall / Mid Cap RiskShort Squeeze RiskHighly Liquid / Institution-Friendly

Key Highlights

Company Size Small-Cap Stock
Market Capitalization 71.58M USD
Price to earnings Ratio -
1Y Target Price 7.2
Price to earnings Ratio -
1Y Target Price 7.2
Volume (30-day avg) 417.1K shares
Beta 0.19
52 Weeks Range 1.53 - 4.34
Updated Date 10/11/2026
52 Weeks Range 1.53 - 4.34
Updated Date 10/11/2026
Dividends yield (FY) -
Basic EPS (TTM) -0.5

How Company Makes Money

Business areaWhat it includesRetail investor read
Drug DevelopmentResearch, development, and eventual licensing of small-molecule therapeutics for rare diseases.The company burns cash to create drugs; revenue will only arrive through future drug sales or licensing deals.
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Valuation

Trailing PE -
Forward PE -
Enterprise Value 68.05M
Price to Sales(TTM) 255.5
Enterprise Value 68.05M
Price to Sales(TTM) 255.5
Enterprise Value to Revenue 138.33
Enterprise Value to EBITDA -1.55
Shares Outstanding 43.64M
Shares Floating 42.64M
Shares Outstanding 43.64M
Shares Floating 42.64M
Percent Insiders 2.23
Percent Institutions 19.82

Financial Metrics

🧭 Investment Snapshot

Total Revenue (Scale)

Information icon Total money earned from selling products or services before any costs. It is needed to understand the scale of the business and its ability to generate income.

Net Income (Profit)

Information icon Final profit after all expenses, interest, and taxes are deducted. It is needed to determine the overall profitability available to shareholders.

Free Cash Flow (Cash Strength)

Information icon Cash remaining after operating activities and capital expenditures, showing cash available for growth. It is needed to evaluate the company’s ability to invest, pay dividends, or reduce debt.

📈 Growth & Strength

Operating Income (Core Profit)

Information icon Profit from core operations after deducting all operating expenses. It is needed to measure how efficiently the company runs its primary business activities.

EBITDA (Cash Earnings)

Information icon Earnings before interest, taxes, depreciation, and amortization, indicating operating cash potential. It is needed to compare operating performance across companies without accounting or financing differences.

Gross Profit (Unit Profitability)

Information icon Revenue minus cost of revenue, showing profit after direct production costs. It is needed to evaluate core business profitability before overhead expenses.

🛡️ Financial Safety

Cash (Liquidity Buffer)

Information icon Total cash and cash equivalents on hand. It is needed to evaluate immediate liquidity and financial flexibility.

Total Debt (Leverage Risk)

Information icon Total debt including both short-term and long-term components. It is needed to assess the company’s leverage and financial risk.

Net Working Capital (Short-Term Health)

Information icon Current assets minus current liabilities, indicating short-term liquidity strength. It is needed to assess whether the company can meet its short-term obligations.

🧱 Balance Sheet Strength

Stockholder Equity (Net Worth)

Information icon Total equity value held by shareholders. It is needed to understand the net worth of the company from the owners’ perspective.

Total Assets (Asset Base)

Information icon The full value of everything the company owns, including cash, inventory, equipment, and investments. It is needed to understand the resource base used to generate revenue.

Income Before Tax (Pre-Tax Earnings)

Information icon Income before provision for income taxes. It is needed to analyze profitability independent of tax structures.

⚙️ Cost & Drag Factors

Cost of Revenue (Production Cost)

Information icon Direct costs required to produce and deliver the products or services sold. It is needed to assess efficiency in production and service delivery.

Total Operating Expenses (Operating Cost)

Information icon Indirect costs of running the business such as salaries, marketing, and administration. It is needed to understand how much it costs to sustain ongoing business operations.

Income Tax Expense (Tax Drag)

Information icon Amount of taxes paid or payable to the government. It is needed to evaluate the impact of taxation on overall profitability.

Form CRS provides a relationship summary of our automated advisory services, flat subscription fees, and conflicts of interest. Form ADV Part 2A brochure contains complete details on services, billing, and disclosures. If any summary differs from our current regulatory filings, the filed Form ADV controls.