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Upturn AI Summary - About
GRI Bio Inc.(GRI)
Advisory History & Simulated Performance *
*as per simulation (see disclosures)- ALL
- 1Y
- 1M
- 1W
- BUY Advisory
- SELL Advisory (Profit)
- SELL Advisory (Loss)
- Profit
- Loss
- PASS (Skip)
Advisory Performance History (Simulated)
Upturn Advisory & Investor View for GRI
11/05/2026: GRI (1-star) is currently NOT-A-BUY. Pass it for now.
GRI Bio Inc. is a small-cap, clinical-stage biotechnology company focused on treating inflammatory and fibrotic diseases by modulating NKT cell activity. Its primary growth story revolves around the potential success of its lead candidate, GRI-0621, in treating idiopathic pulmonary fibrosis. While the company possesses a research-heavy platform, it is currently pre-revenue and faces high risks related to clinical trial outcomes, limited cash resources, and intense competition from larger pharmaceutical entities. The stock is best suited for speculative investors with a high risk tolerance who are closely monitoring clinical developments and dilution trends. It is not currently suitable for value or dividend-focused portfolios.
How to Read the Upturn Advisory
The Upturn Star Rating and the current BUY, SELL, or PASS advisory are generated by Upturn’s AI advisory engine based on proprietary signal analysis, price behavior, advisory history, and historical signal performance.
Company fundamentals, valuation, risks, and news provide supporting context about the business.
Investor Fit
| Investor style | Fit | Why |
|---|---|---|
| Growth investor | Mixed fit | While the company focuses on high-growth biotech, its extreme early-stage risk makes it a speculative rather than traditional growth play. |
| Momentum investor | Strong fit while signal remains positive | This stock is highly volatile and often subject to intense trading activity around clinical trial updates. |
| Value investor | Weak fit | The company is pre-revenue and clinical-stage, offering no traditional value metrics to evaluate. |
| Dividend investor | Weak fit | GRI Bio does not pay dividends and is focused on cash burn for R&D. |
| Low-risk investor | Weak fit | The company's clinical-stage nature and extreme price volatility are unsuitable for low-risk portfolios. |
Risk Profile
| Risk factor | Level | Why it matters |
|---|---|---|
| Price volatility | High | The stock is highly sensitive to news flow regarding clinical trials and financing needs. |
| Valuation risk | High | With limited assets and no revenue, the company's valuation is speculative and subject to rapid adjustment. |
| Competition risk (clinical/biotech) | High | Well-funded competitors in fibrosis and autoimmune disease could render GRI's pipeline less attractive. |
| Business quality | Low | The firm is in the early research phase with limited commercial infrastructure or revenue. |
| Dividend income | Low / none | There is no dividend income and the firm is cash-burning. |
| Execution risk | High | Clinical success is uncertain and failure could be catastrophic for the business model. |
Price Behavior

Steep Decline
The stock price has dropped sharply with strong downward pressure.

Extreme Price Shocks
The stock has experienced exceptionally large and disruptive price movements during the period.
Analysis of Past Performance
Type Stock | Historic Profit -73.47% | Avg. Invested days 11 | Today’s Advisory PASS |
Upturn Advisory Rating ![]() | Upturn Advisory Performance | Stock Returns Performance |
Upturn Scorecard
Upturn Star Rating 
Company Fundamentals 
Financial Health Rating 
Growth Momentum Score 
Ownership 
Top 5 Institutional Investors
Unit Economics (Per $1K Revenue) 
Economic Dimensions
Quantitative Style Profile 
Style Classification
Quality Focused
Key Highlights
Company Size Small-Cap Stock | Market Capitalization 3.13M USD | Price to earnings Ratio - | 1Y Target Price 18.5 |
Price to earnings Ratio - | 1Y Target Price 18.5 | ||
Volume (30-day avg) 46.0K shares | Beta -0.59 | 52 Weeks Range 1.36 - 64.12 | Updated Date 11/04/2026 |
52 Weeks Range 1.36 - 64.12 | Updated Date 11/04/2026 | ||
Dividends yield (FY) - | Basic EPS (TTM) -13.75 |
How Company Makes Money
| Business area | What it includes | Retail investor read |
|---|---|---|
| Drug Development | Clinical testing and development of NKT cell modulators like GRI-0621. | The company currently spends money on research and does not generate regular revenue from product sales. |
Valuation
Trailing PE - | Forward PE - | Enterprise Value -7.56M | Price to Sales(TTM) - |
Enterprise Value -7.56M | Price to Sales(TTM) - | ||
Enterprise Value to Revenue - | Enterprise Value to EBITDA - | Shares Outstanding 2.19M | Shares Floating 2.19M |
Shares Outstanding 2.19M | Shares Floating 2.19M | ||
Percent Insiders 0.38 | Percent Institutions 4.28 |
Financial Metrics
🧭 Investment Snapshot
Total Revenue (Scale)
Total money earned from selling products or services before any costs. It is needed to understand the scale of the business and its ability to generate income.
Net Income (Profit)
Final profit after all expenses, interest, and taxes are deducted. It is needed to determine the overall profitability available to shareholders.
Free Cash Flow (Cash Strength)
Cash remaining after operating activities and capital expenditures, showing cash available for growth. It is needed to evaluate the company’s ability to invest, pay dividends, or reduce debt.
📈 Growth & Strength
Operating Income (Core Profit)
Profit from core operations after deducting all operating expenses. It is needed to measure how efficiently the company runs its primary business activities.
EBITDA (Cash Earnings)
Earnings before interest, taxes, depreciation, and amortization, indicating operating cash potential. It is needed to compare operating performance across companies without accounting or financing differences.
Gross Profit (Unit Profitability)
Revenue minus cost of revenue, showing profit after direct production costs. It is needed to evaluate core business profitability before overhead expenses.
🛡️ Financial Safety
Cash (Liquidity Buffer)
Total cash and cash equivalents on hand. It is needed to evaluate immediate liquidity and financial flexibility.
Total Debt (Leverage Risk)
Total debt including both short-term and long-term components. It is needed to assess the company’s leverage and financial risk.
Net Working Capital (Short-Term Health)
Current assets minus current liabilities, indicating short-term liquidity strength. It is needed to assess whether the company can meet its short-term obligations.
🧱 Balance Sheet Strength
Stockholder Equity (Net Worth)
Total equity value held by shareholders. It is needed to understand the net worth of the company from the owners’ perspective.
Total Assets (Asset Base)
The full value of everything the company owns, including cash, inventory, equipment, and investments. It is needed to understand the resource base used to generate revenue.
Income Before Tax (Pre-Tax Earnings)
Income before provision for income taxes. It is needed to analyze profitability independent of tax structures.
⚙️ Cost & Drag Factors
Cost of Revenue (Production Cost)
Direct costs required to produce and deliver the products or services sold. It is needed to assess efficiency in production and service delivery.
Total Operating Expenses (Operating Cost)
Indirect costs of running the business such as salaries, marketing, and administration. It is needed to understand how much it costs to sustain ongoing business operations.
Income Tax Expense (Tax Drag)
Amount of taxes paid or payable to the government. It is needed to evaluate the impact of taxation on overall profitability.

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