GlaxoSmithKline PLC ADR logo

GlaxoSmithKline PLC ADR(GSK)

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ADVISORIES YOU CAN VERIFY
QUALITY SIGNAL
1-STAR RATING
PASS
LAST CLOSE
$47.03
10/02/2026
(24-hour delay)

Advisory History & Simulated Performance *

*as per simulation (see disclosures)
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Upturn Advisory & Investor View for GSK

10/02/2026: GSK (1-star) is currently NOT-A-BUY. Pass it for now.

GSK is a focused global biopharmaceutical company specializing in vaccines, HIV therapeutics, and specialty medicines. The company has successfully transitioned into a pure-play entity following the spin-off of its consumer healthcare business, allowing for greater investment in high-margin research areas. Its leading market position in vaccines, particularly with the Arexvy RSV vaccine, represents a primary growth driver. However, the firm faces significant execution risks, including intense competition from generic and biosimilar producers, as well as ongoing challenges related to product patent expirations. GSK is generally well-suited for value-oriented and dividend-focused investors seeking exposure to the stable, large-cap pharmaceutical sector.

How to Read the Upturn Advisory

The Upturn Star Rating and the current BUY, SELL, or PASS advisory are generated by Upturn’s AI advisory engine based on proprietary signal analysis, price behavior, advisory history, and historical signal performance.

Company fundamentals, valuation, risks, and news provide supporting context about the business.

Investor Fit

Investor styleFitWhy
Growth investorMixed fitGSK is a mature, slow-growth pharmaceutical firm rather than a high-growth tech or biotech innovator.
Momentum investorMixed fitMomentum is conditional on positive regulatory milestones or clinical data that cause significant stock upturns.
Value investorStrong fitThe stock is often viewed as reasonably valued relative to its cash flow generation and dividend stability.
Dividend investorStrong fitGSK offers a consistent dividend yield, making it an attractive option for income-seeking portfolios.
Low-risk investorStrong fitAs a large-cap pharmaceutical company, it generally exhibits lower volatility compared to smaller, speculative biotech stocks.

Risk Profile

Risk factorLevelWhy it matters
Price volatilityMediumPharmaceutical stocks can fluctuate significantly based on clinical trial results and regulatory decisions.
Valuation riskLowThe stock generally trades within a predictable range relative to sector peers.
Competition risk (HIV/Vaccines)HighGSK faces intense competition from companies like Gilead and Pfizer in its most profitable segments.
Business qualityStrongThe firm has a long-standing history of global drug development and market presence.
Dividend incomeLow / noneThe dividend is supported by stable cash flows, though payout ratios remain a factor to monitor.
Execution riskMediumThe company must successfully navigate the complex transition to a pure-play model while maintaining R&D output.

Price Behavior

Downtrend
PRICE PATH

Downtrend

The stock has experienced a sustained decline in price over recent periods.

Smooth
PRICE STABILITY

Smooth

The stock has moved along a generally orderly path with only modest fluctuations.

Analysis of Past Performance

Type Stock
Historic Profit 6.15%
Avg. Invested days 44
Today’s Advisory PASS
Upturn Advisory Rating upturn star rating icon
Upturn Advisory Performance Upturn Advisory Performance icon 1.0
Stock Returns Performance Upturn Returns Performance icon 2.0
Upturn Profits based on simulation icon Profits based on simulation
Upturn last close icon Last Close 10/02/2026

Upturn Scorecard

Upturn Star Rating

★★★★★
GSK receives a 4-star rating, supported by strong unit economics, solid company fundamentals, and solid quantitative characteristics. The rating is constrained by weak price momentum.

Company Fundamentals

★★★★★
GSK has solid overall fundamentals (4 stars), with solid financial health, solid growth momentum, and moderate ownership. In FY2025 versus FY2024, strong earnings growth (+122.0%) and strong cash generation (FCF margin 17.8%) are partially offset by moderate revenue growth (+4.1%), very low insider ownership of 0.06%.

Financial Health Rating

★★★★★
GSK's financial health is supported by strong cash strength, including free-cash-flow generation of $5.8B (17.8% of revenue). Liquidity is moderate (3 stars), which helps explain the 4-star overall score.

Growth Momentum Score

★★★★★
Earnings growth is GSK's strongest growth driver at +122.0% FY2025 versus FY2024 (strong, 5 stars). By comparison, free-cash-flow growth (+63.1%, strong) is also strong, while revenue growth (+4.1%, moderate) holds the profile back, so recent growth is not broad-based across the business.

Ownership

★★★★★
Institutional ownership is 17.5% (soft) and 96.9% of outstanding shares are publicly tradable (strong). Insider ownership is only 0.06%, which materially reduces the ownership score.

Top 5 Institutional Investors

FMR Inc 3.24%
Dodge & Cox 2.41%
Fisher Asset Management, LLC 1.78%
PRIMECAP Management Company 1.26%
Wellington Management Company LLP 0.57%

Unit Economics (Per $1K Revenue)

★★★★★
GSK generates approximately $724 of gross profit, $255 of operating income, and $178 of free cash flow for every $1,000 of revenue. Based on FY2025 results. Strong margins, cash conversion, and capital efficiency support the rating.

Economic Dimensions

★★★★★
Effective Tax Rate: 15.02%

Quantitative Style Profile

★★★★★
GSK has a high-quality, large-cap, liquid, relatively low-volatility profile. Weak momentum is the primary drawback.

Style Classification

Quality Focused

Value-OrientedQuality TiltLow VolatilityLarge / Mega Cap StabilityHighly Liquid / Institution-Friendly

Key Highlights

Company Size Large-Cap Stock
Market Capitalization 94.53B USD
Price to earnings Ratio 15.47
1Y Target Price 59.58
Price to earnings Ratio 15.47
1Y Target Price 59.58
Volume (30-day avg) 3.2M shares
Beta 0.29
52 Weeks Range 41.38 - 60.11
Updated Date 10/02/2026
52 Weeks Range 41.38 - 60.11
Updated Date 10/02/2026
Dividends yield (FY) 3.85%
Basic EPS (TTM) 3.05

How Company Makes Money

Business areaWhat it includesRetail investor read
Specialty MedicinesHIV drugs, immunology therapies, and oncology medications.This is the primary revenue driver, focused on high-margin, specialized patient care.
VaccinesShingrix, Arexvy, and other preventive health vaccines.A highly defensible business segment with recurring demand and high barriers to entry.
General MedicinesEstablished respiratory and skin treatment portfolios.Provides reliable, stable cash flow from widely used, mature medical products.

Analyzing Revenue: Products, Geography and Growth

Revenue by Products

Product revenue - Year on Year

Revenue by Geography

Geography revenue - Year on Year

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Valuation

Trailing PE 15.47
Forward PE 9.77
Enterprise Value 122.33B
Price to Sales(TTM) 2.85
Enterprise Value 122.33B
Price to Sales(TTM) 2.85
Enterprise Value to Revenue 2.76
Enterprise Value to EBITDA 9.45
Shares Outstanding 2.00B
Shares Floating 1.94B
Shares Outstanding 2.00B
Shares Floating 1.94B
Percent Insiders 0.06
Percent Institutions 17.48

Icon representing Upturn AI-generated SWOT analysis summary Upturn AI Summary

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Financial Metrics

🧭 Investment Snapshot

Total Revenue (Scale)

Information icon Total money earned from selling products or services before any costs. It is needed to understand the scale of the business and its ability to generate income.

Net Income (Profit)

Information icon Final profit after all expenses, interest, and taxes are deducted. It is needed to determine the overall profitability available to shareholders.

Free Cash Flow (Cash Strength)

Information icon Cash remaining after operating activities and capital expenditures, showing cash available for growth. It is needed to evaluate the company’s ability to invest, pay dividends, or reduce debt.

📈 Growth & Strength

Operating Income (Core Profit)

Information icon Profit from core operations after deducting all operating expenses. It is needed to measure how efficiently the company runs its primary business activities.

EBITDA (Cash Earnings)

Information icon Earnings before interest, taxes, depreciation, and amortization, indicating operating cash potential. It is needed to compare operating performance across companies without accounting or financing differences.

Gross Profit (Unit Profitability)

Information icon Revenue minus cost of revenue, showing profit after direct production costs. It is needed to evaluate core business profitability before overhead expenses.

🛡️ Financial Safety

Cash (Liquidity Buffer)

Information icon Total cash and cash equivalents on hand. It is needed to evaluate immediate liquidity and financial flexibility.

Total Debt (Leverage Risk)

Information icon Total debt including both short-term and long-term components. It is needed to assess the company’s leverage and financial risk.

Net Working Capital (Short-Term Health)

Information icon Current assets minus current liabilities, indicating short-term liquidity strength. It is needed to assess whether the company can meet its short-term obligations.

🧱 Balance Sheet Strength

Stockholder Equity (Net Worth)

Information icon Total equity value held by shareholders. It is needed to understand the net worth of the company from the owners’ perspective.

Total Assets (Asset Base)

Information icon The full value of everything the company owns, including cash, inventory, equipment, and investments. It is needed to understand the resource base used to generate revenue.

Income Before Tax (Pre-Tax Earnings)

Information icon Income before provision for income taxes. It is needed to analyze profitability independent of tax structures.

⚙️ Cost & Drag Factors

Cost of Revenue (Production Cost)

Information icon Direct costs required to produce and deliver the products or services sold. It is needed to assess efficiency in production and service delivery.

Total Operating Expenses (Operating Cost)

Information icon Indirect costs of running the business such as salaries, marketing, and administration. It is needed to understand how much it costs to sustain ongoing business operations.

Income Tax Expense (Tax Drag)

Information icon Amount of taxes paid or payable to the government. It is needed to evaluate the impact of taxation on overall profitability.

News (Last Updated: 10/02/2026)

About GlaxoSmithKline PLC ADR

Exchange NYSE
Headquarters -
IPO Launch date 1986-07-09
CEO & Director Mr. Luke Victor Miels
Sector Healthcare
Industry Drug Manufacturers - General
Full time employees 66841
Full time employees 66841

GSK plc, together with its subsidiaries, engages in the research, development, and manufacture of vaccines, specialty medicines, and general medicines to prevent and treat disease in the United Kingdom, the United States, and internationally. It operates through Commercial Operations and Total R&D segments. The company offers specialty medicines that include oncology, respiratory/immunology, inflammation, and inhaled medicines for HIV, respiratory eosinophildriven diseases, lupus and lupus nephritis, ovarian cancer, and endometrial cancer. It also provides vaccines for Shingles, Meningitis, RSV, Seasonal Influenza, Hepatitis, Diphtheria, Tetanus, Acellular Pertussis, Rotavirus, Pertussis, Polio, Haemophilus, Invasive Diseases, Pneumonia, Acute Otitis Media, Measles, Mumps, Rubella and Chickenpox, and Human Papilloma Virus. Additionally, the company offers general medicines for asthma, COPD, bacterial infection, benign prostatic hyperplasia, allergic rhinitis, and inflammatory skin conditions. It also focuses on the discovery, development, and commercialization of oral small molecule therapies for patients with unmet needs in oncology and inflammatory diseases. It has a collaboration agreement with CureVac to develop mRNA vaccines for infectious diseases; and strategic research collaboration with Engitix Ltd. to identify and validate novel therapeutic targets driving liver fibrosis regression. The company has a strategic alliance with AN2 Therapeutics, Inc. for the development of new therapies for TB. GSK plc was formerly known as GlaxoSmithKline plc and changed its name to GSK plc in May 2022. The company was founded in 1715 and is headquartered in London, United Kingdom.