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Gyre Therapeutics Inc. (GYRE)

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Upturn Advisory Summary
12/16/2025: GYRE (1-star) is currently NOT-A-BUY. Pass it for now.
1 Year Target Price $18
1 Year Target Price $18
| 1 | Strong Buy |
| 0 | Buy |
| 0 | Hold |
| 0 | Sell |
| 0 | Strong Sell |
Analysis of Past Performance
Type Stock | Historic Profit 2.54% | Avg. Invested days 19 | Today’s Advisory PASS |
Upturn Star Rating ![]() | Upturn Advisory Performance | Stock Returns Performance |
Key Highlights
Company Size Small-Cap Stock | Market Capitalization 726.35M USD | Price to earnings Ratio 188.5 | 1Y Target Price 18 |
Price to earnings Ratio 188.5 | 1Y Target Price 18 | ||
Volume (30-day avg) 1 | Beta 7.07 | 52 Weeks Range 6.11 - 14.42 | Updated Date 12/16/2025 |
52 Weeks Range 6.11 - 14.42 | Updated Date 12/16/2025 | ||
Dividends yield (FY) - | Basic EPS (TTM) 0.04 |
Analyzing Revenue: Products, Geography and Growth
Revenue by Products
Product revenue - Year on Year
Earnings Date
Report Date - | When - | Estimate - | Actual - |
Profitability
Profit Margin 6.2% | Operating Margin (TTM) 22.66% |
Management Effectiveness
Return on Assets (TTM) 5.28% | Return on Equity (TTM) 10.02% |
Valuation
Trailing PE 188.5 | Forward PE 75.19 | Enterprise Value 666504672 | Price to Sales(TTM) 6.77 |
Enterprise Value 666504672 | Price to Sales(TTM) 6.77 | ||
Enterprise Value to Revenue 6.21 | Enterprise Value to EBITDA 46.42 | Shares Outstanding 96333157 | Shares Floating 20523048 |
Shares Outstanding 96333157 | Shares Floating 20523048 | ||
Percent Insiders 87.1 | Percent Institutions 3.44 |
About Gyre Therapeutics Inc.
Exchange NASDAQ | Headquaters San Diego, CA, United States | ||
IPO Launch date 2006-04-12 | Interim CEO & Executive Chair Mr. Ping Zhang | ||
Sector Healthcare | Industry Biotechnology | Full time employees 579 | Website https://www.gyretx.com |
Full time employees 579 | Website https://www.gyretx.com | ||
Gyre Therapeutics, Inc., a pharmaceutical company, engages in the development and commercialization of small-molecule, anti-inflammatory, and anti-fibrotic drugs targeting organ fibrosis. The company offers ETUARY (Pirfenidone), an anti-fibrotic drug approved for the treatment of idiopathic pulmonary fibrosis; and under Phase 3 trials for the treatment of pneumoconiosis. It is also involved in the development of F351 (Hydronidone), a structural derivative of ETUARY, under Phase 3 trials for the treatment of chronic hepatitis B (CHB)-associated liver fibrosis; and completed Phase 1 trials for the treatment of liver fibrosis associated with metabolic dysfunction-associated steatohepatitis. In addition, the company develops F573 is in Phase 2 clinical trials for the treatment of acute/acute-on-chronic liver failure. Further, its preclinical products include F230 for the treatment of pulmonary arterial hypertension; and F528 to treat chronic obstructive pulmonary disease. The company was founded in 2002 and is headquartered in San Diego, California. Gyre Therapeutics, Inc. operates as a subsidiary of GNI USA, Inc.

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