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Upturn AI Summary - About
Heron Therapeuti(HRTX)
Advisory History & Simulated Performance *
*as per simulation (see disclosures)- ALL
- 1Y
- 1M
- 1W
- BUY Advisory
- SELL Advisory (Profit)
- SELL Advisory (Loss)
- Profit
- Loss
- PASS (Skip)
Stock price based on last close Advisory Performance History (Simulated)
Upturn Advisory & Investor View for HRTX
10/08/2026: HRTX (1-star) is currently NOT-A-BUY. Pass it for now.
Heron Therapeutics is a commercial-stage biotechnology company that focuses on developing supportive care products for oncology patients and non-opioid pain management solutions. Its main strength lies in its proprietary drug delivery platform, which enables long-acting therapeutic effects. The company’s primary investment story centers on the market penetration of its flagship pain management product, ZYNRELEF. Key risks include intense competition from established pharmaceutical players, the challenge of achieving sustained profitability, and potential dilution from financing needs. This stock may suit investors who are comfortable with the volatility of the biotech sector and who wish to monitor the company’s ability to gain meaningful market share in its core therapeutic areas.
How to Read the Upturn Advisory
The Upturn Star Rating and the current BUY, SELL, or PASS advisory are generated by Upturn’s AI advisory engine based on proprietary signal analysis, price behavior, advisory history, and historical signal performance.
Company fundamentals, valuation, risks, and news provide supporting context about the business.
Investor Fit
| Investor style | Fit | Why |
|---|---|---|
| Growth investor | Mixed fit | The company offers growth potential through product adoption but carries high commercialization risk. |
| Momentum investor | Weak fit | Momentum is highly dependent on positive commercial signal and earnings surprises. |
| Value investor | Weak fit | The lack of consistent profitability makes valuation-based investing difficult. |
| Dividend investor | Weak fit | The company does not pay a dividend and focuses on cash preservation. |
| Low-risk investor | Weak fit | Small-cap biotechnology stocks exhibit high volatility and binary regulatory risks. |
Risk Profile
| Risk factor | Level | Why it matters |
|---|---|---|
| Price volatility | High | Biotech stocks are highly sensitive to clinical data and commercial sales updates. |
| Valuation risk | Medium / high | Valuation is sensitive to future cash flow expectations which remain uncertain. |
| Competition risk (Pain Management) | High | ZYNRELEF faces stiff competition from established products like Exparel. |
| Business quality | Medium | The company has transitioned to commercial stage but still requires scale. |
| Dividend income | Low / none | No income is returned to shareholders. |
| Execution risk | High | Commercializing new therapeutics is difficult and resource-intensive. |
Price Behavior
Steep Decline
The stock price has dropped sharply with strong downward pressure.
Extreme Price Shocks
The stock has experienced exceptionally large and disruptive price movements during the period.
Analysis of Past Performance
Type Stock | Historic Profit -4.04% | Avg. Invested days 27 | Today’s Advisory PASS |
Upturn Advisory Rating  | Upturn Advisory Performance  2.0 | Stock Returns Performance  1.0 |
| Profits based on simulation | Last Close 10/08/2026 |
Upturn Scorecard
Upturn Star Rating 
Company Fundamentals
Financial Health Rating
Growth Momentum Score
Ownership
Top 5 Institutional Investors
Unit Economics (Per $1K Revenue)
Economic Dimensions
Quantitative Style Profile
Style Classification
Quality Focused
Key Highlights
Company Size Small-Cap Stock | Market Capitalization 72.96M USD | Price to earnings Ratio - | 1Y Target Price 7 |
Price to earnings Ratio - | 1Y Target Price 7 | ||
Volume (30-day avg) 2.3M shares | Beta 1.62 | 52 Weeks Range 0.26 - 1.57 | Updated Date 10/08/2026 |
52 Weeks Range 0.26 - 1.57 | Updated Date 10/08/2026 | ||
Dividends yield (FY) - | Basic EPS (TTM) -0.21 |
How Company Makes Money
| Business area | What it includes | Retail investor read |
|---|---|---|
| Oncology Support | Sales of SUSTOL and CINVETI for nausea prevention. | Revenue comes from products that support patients undergoing chemotherapy. |
| Acute Care | Sales of ZYNRELEF for post-operative pain management. | Revenue is linked to the adoption of non-opioid pain relief in surgery centers. |
Analyzing Revenue: Products, Geography and Growth
Revenue by Products
Product revenue - Year on Year
Valuation
Trailing PE - | Forward PE 46.95 | Enterprise Value 162.01M | Price to Sales(TTM) 0.48 |
Enterprise Value 162.01M | Price to Sales(TTM) 0.48 | ||
Enterprise Value to Revenue 1.07 | Enterprise Value to EBITDA 49.68 | Shares Outstanding 189.85M | Shares Floating 146.52M |
Shares Outstanding 189.85M | Shares Floating 146.52M | ||
Percent Insiders 0.98 | Percent Institutions 71 |
Financial Metrics
🧭 Investment Snapshot
Total Revenue (Scale)
Total money earned from selling products or services before any costs. It is needed to understand the scale of the business and its ability to generate income.
Net Income (Profit)
Final profit after all expenses, interest, and taxes are deducted. It is needed to determine the overall profitability available to shareholders.
Free Cash Flow (Cash Strength)
Cash remaining after operating activities and capital expenditures, showing cash available for growth. It is needed to evaluate the company’s ability to invest, pay dividends, or reduce debt.
📈 Growth & Strength
Operating Income (Core Profit)
Profit from core operations after deducting all operating expenses. It is needed to measure how efficiently the company runs its primary business activities.
EBITDA (Cash Earnings)
Earnings before interest, taxes, depreciation, and amortization, indicating operating cash potential. It is needed to compare operating performance across companies without accounting or financing differences.
Gross Profit (Unit Profitability)
Revenue minus cost of revenue, showing profit after direct production costs. It is needed to evaluate core business profitability before overhead expenses.
🛡️ Financial Safety
Cash (Liquidity Buffer)
Total cash and cash equivalents on hand. It is needed to evaluate immediate liquidity and financial flexibility.
Total Debt (Leverage Risk)
Total debt including both short-term and long-term components. It is needed to assess the company’s leverage and financial risk.
Net Working Capital (Short-Term Health)
Current assets minus current liabilities, indicating short-term liquidity strength. It is needed to assess whether the company can meet its short-term obligations.
🧱 Balance Sheet Strength
Stockholder Equity (Net Worth)
Total equity value held by shareholders. It is needed to understand the net worth of the company from the owners’ perspective.
Total Assets (Asset Base)
The full value of everything the company owns, including cash, inventory, equipment, and investments. It is needed to understand the resource base used to generate revenue.
Income Before Tax (Pre-Tax Earnings)
Income before provision for income taxes. It is needed to analyze profitability independent of tax structures.
⚙️ Cost & Drag Factors
Cost of Revenue (Production Cost)
Direct costs required to produce and deliver the products or services sold. It is needed to assess efficiency in production and service delivery.
Total Operating Expenses (Operating Cost)
Indirect costs of running the business such as salaries, marketing, and administration. It is needed to understand how much it costs to sustain ongoing business operations.
Income Tax Expense (Tax Drag)
Amount of taxes paid or payable to the government. It is needed to evaluate the impact of taxation on overall profitability.
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