Incyte Corporation logo

Incyte Corporation(INCY)

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EXPLORE ADVISORIES AND THEIR HISTORY
QUALITY SIGNAL
5-STAR RATING
PASS
LAST CLOSE
$119.65
11/06/2026
(24-hour delay)

Advisory History & Simulated Performance *

*as per simulation (see disclosures)
  • ALL
  • 1Y
  • 1M
  • 1W
  • BUY Advisory
  • SELL Advisory (Profit)
  • SELL Advisory (Loss)
  • Profit
  • Loss
  • PASS (Skip)
Upturn Stock price based on last close iconStock price based on last close
Simulated performance—not actual client returns. Excludes advisory subscription fees, trading commissions, and taxes, which would reduce returns. Results depend on calculation assumptions and do not guarantee future outcomes. See Disclosures for full methodology, assumptions, and limitations.

Advisory Performance History (Simulated)Advisory Performance History info

Simulated performance—not actual client returns. Excludes advisory subscription fees, trading commissions, and taxes, which would reduce returns. Results depend on calculation assumptions and do not guarantee future outcomes. See Disclosures for full methodology, assumptions, and limitations.

Upturn Advisory & Investor View for INCY

11/06/2026: INCY (5-star) is currently NOT-A-BUY. Pass it for now.

Incyte Corporation is a mid-to-large cap biotechnology company focused on developing targeted therapeutics for oncology and inflammatory diseases. Its primary financial strength is the well-established commercial performance of its flagship product, Jakafi, which provides a solid revenue base. The company's main growth story centers on its ability to expand its JAK inhibition platform into new dermatological markets with products like Opzelura. However, investors must monitor risks related to the company's revenue concentration, the patent landscape for its core drug, and intense competition in the biopharma space. The stock may best suit growth-oriented investors interested in clinical innovation who are comfortable with the inherent volatility of the biotechnology sector.

How to Read the Upturn Advisory

The Upturn Star Rating and the current BUY, SELL, or PASS advisory are generated by Upturn’s AI advisory engine based on proprietary signal analysis, price behavior, advisory history, and historical signal performance.

Company fundamentals, valuation, risks, and news provide supporting context about the business.

Investor Fit

Investor styleFitWhy
Growth investorStrong fitIncyte's focus on innovative therapies and pipeline development appeals to those seeking long-term capital appreciation.
Momentum investorMixed fitMomentum exposure is conditional on positive clinical data readouts or commercial growth surges.
Value investorWeak fitThe company's valuation is often tied to pipeline potential rather than traditional price-to-earnings metrics.
Dividend investorWeak fitIncyte does not pay a dividend, making it unsuitable for income-focused portfolios.
Low-risk investorWeak fitBiotech stocks face high clinical and regulatory risks, making them unsuitable for risk-averse investors.

Risk Profile

Risk factorLevelWhy it matters
Price volatilityHighBiotech stocks often react sharply to clinical trial results and FDA decisions.
Valuation riskMediumFuture growth expectations are already priced in, which can lead to corrections if pipelines underperform.
Competition risk (JAK inhibition)HighSeveral large players are developing competing therapies for similar indications.
Business qualityMediumThe company has a strong commercial product but faces concentration risk regarding its core portfolio.
Dividend incomeLow / noneThe company retains earnings for growth rather than returning cash to shareholders.
Execution riskMediumSuccessfully transitioning from a single-product company to a diversified entity is complex and carries execution risk.

Price Behavior

Strong Uptrend
PRICE PATH

Strong Uptrend

The stock has maintained a strong upward price trend across the last three quarters.

Smooth
PRICE STABILITY

Smooth

The stock has moved along a generally orderly path with only modest fluctuations.

Analysis of Past Performance

Type Stock
Historic Profit 46.03%
Avg. Invested days 49
Today’s Advisory PASS
Upturn Advisory Rating upturn star rating icon
Upturn Advisory Performance Upturn Advisory Performance icon 3.0
Stock Returns Performance Upturn Returns Performance icon 3.0
Upturn Profits based on simulation icon Profits based on simulation
Upturn last close icon Last Close 11/06/2026

Upturn Scorecard

Upturn Star Rating

★★★★★
INCY receives a 4-star rating, supported by strong unit economics, solid company fundamentals, and solid analyst coverage. The rating is constrained by weak price momentum, and limited analyst upside.

Company Fundamentals

★★★★★
INCY has solid overall fundamentals (4 stars), with solid financial health, strong growth momentum, and solid ownership. In FY2025 versus FY2024, strong earnings growth (+3845.0%) and strong cash generation (FCF margin 26.3%) are partially offset by modest insider ownership of 1.83%.

Financial Health Rating

★★★★★
INCY's financial health is supported by strong cash strength, including free-cash-flow generation of $1.4B (26.3% of revenue). Operating efficiency is solid (4 stars), which helps explain the 4-star overall score.

Growth Momentum Score

★★★★★
Earnings growth is INCY's strongest growth driver at +3845.0% FY2025 versus FY2024 (strong, 5 stars). Revenue growth (+21.2%, solid) and free-cash-flow growth (+443.9%, strong) are also constructive, though not equally high across every growth measure.

Ownership

★★★★★
Institutional ownership is 103.3% and approximately 84.2% of outstanding shares are publicly tradable, supporting liquidity and institutional participation. Insider ownership of 1.83% provides only moderate management-shareholder alignment.

Top 5 Institutional Investors

Baker Bros Advisors LP 15.09%
BlackRock Inc 8.85%
Dodge & Cox 5.87%
Vanguard Capital Management, LLC 5.41%
State Street Corp 4.77%

Unit Economics (Per $1K Revenue)

★★★★★
INCY generates approximately $928 of gross profit, $261 of operating income, and $263 of free cash flow for every $1,000 of revenue. Based on FY2025 results. Strong margins, cash conversion, and capital efficiency support the rating.

Economic Dimensions

★★★★★
Effective Tax Rate: 22.70%

Quantitative Style Profile

★★★★★
INCY has a high-quality, large-cap, liquid, relatively low-volatility profile. Weak momentum is the primary drawback, while valuation that is moderately attractive rather than deeply discounted.

Style Classification

Quality Focused

Quality TiltLow VolatilityLarge / Mega Cap StabilityShort Squeeze RiskHighly Liquid / Institution-Friendly

Key Highlights

Company Size Large-Cap Stock
Market Capitalization 24.39B USD
Price to earnings Ratio 61.05
1Y Target Price 131.5
Price to earnings Ratio 61.05
1Y Target Price 131.5
Volume (30-day avg) 1.9M shares
Beta 0.78
52 Weeks Range 89.25 - 132.60
Updated Date 11/08/2026
52 Weeks Range 89.25 - 132.60
Updated Date 11/08/2026
Dividends yield (FY) -
Basic EPS (TTM) 1.96

How Company Makes Money

Business areaWhat it includesRetail investor read
Hematology and OncologyJakafi, Pemazyre, and related royalty revenue.Most of the company's money comes from selling drugs that treat specific types of blood cancers.
Inflammation and DermatologyOpzelura cream for skin conditions.This is the company's emerging growth area focused on dermatology.

Analyzing Revenue: Products, Geography and Growth

Revenue by Products

Product revenue - Year on Year

Revenue by Geography

Geography revenue - Year on Year

Valuation

Trailing PE 61.05
Forward PE 13.42
Enterprise Value 20.58B
Price to Sales(TTM) 4.06
Enterprise Value 20.58B
Price to Sales(TTM) 4.06
Enterprise Value to Revenue 3.42
Enterprise Value to EBITDA 22.94
Shares Outstanding 203.83M
Shares Floating 171.56M
Shares Outstanding 203.83M
Shares Floating 171.56M
Percent Insiders 1.83
Percent Institutions 103.3

Financial Metrics

🧭 Investment Snapshot

Total Revenue (Scale)

Information icon Total money earned from selling products or services before any costs. It is needed to understand the scale of the business and its ability to generate income.

Net Income (Profit)

Information icon Final profit after all expenses, interest, and taxes are deducted. It is needed to determine the overall profitability available to shareholders.

Free Cash Flow (Cash Strength)

Information icon Cash remaining after operating activities and capital expenditures, showing cash available for growth. It is needed to evaluate the company’s ability to invest, pay dividends, or reduce debt.

📈 Growth & Strength

Operating Income (Core Profit)

Information icon Profit from core operations after deducting all operating expenses. It is needed to measure how efficiently the company runs its primary business activities.

EBITDA (Cash Earnings)

Information icon Earnings before interest, taxes, depreciation, and amortization, indicating operating cash potential. It is needed to compare operating performance across companies without accounting or financing differences.

Gross Profit (Unit Profitability)

Information icon Revenue minus cost of revenue, showing profit after direct production costs. It is needed to evaluate core business profitability before overhead expenses.

🛡️ Financial Safety

Cash (Liquidity Buffer)

Information icon Total cash and cash equivalents on hand. It is needed to evaluate immediate liquidity and financial flexibility.

Total Debt (Leverage Risk)

Information icon Total debt including both short-term and long-term components. It is needed to assess the company’s leverage and financial risk.

Net Working Capital (Short-Term Health)

Information icon Current assets minus current liabilities, indicating short-term liquidity strength. It is needed to assess whether the company can meet its short-term obligations.

🧱 Balance Sheet Strength

Stockholder Equity (Net Worth)

Information icon Total equity value held by shareholders. It is needed to understand the net worth of the company from the owners’ perspective.

Total Assets (Asset Base)

Information icon The full value of everything the company owns, including cash, inventory, equipment, and investments. It is needed to understand the resource base used to generate revenue.

Income Before Tax (Pre-Tax Earnings)

Information icon Income before provision for income taxes. It is needed to analyze profitability independent of tax structures.

⚙️ Cost & Drag Factors

Cost of Revenue (Production Cost)

Information icon Direct costs required to produce and deliver the products or services sold. It is needed to assess efficiency in production and service delivery.

Total Operating Expenses (Operating Cost)

Information icon Indirect costs of running the business such as salaries, marketing, and administration. It is needed to understand how much it costs to sustain ongoing business operations.

Income Tax Expense (Tax Drag)

Information icon Amount of taxes paid or payable to the government. It is needed to evaluate the impact of taxation on overall profitability.

Form CRS provides a relationship summary of our automated advisory services, flat subscription fees, and conflicts of interest. Form ADV Part 2A brochure contains complete details on services, billing, and disclosures. If any summary differs from our current regulatory filings, the filed Form ADV controls.