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Upturn stock rating
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Ironwood Pharmaceuticals Inc (IRWD)

Upturn stock rating
$1.61
Last Close (24-hour delay)
upturn advisory
PASS
  • BUY Advisory
  • SELL Advisory (Profit)​
  • SELL Advisory (Loss)​
  • Profit
  • Loss
  • Pass (Skip investing)
Upturn Stock info Stock price based on last close
*as per simulation
(see disclosures)
Time period over
  • ALL
  • YEAR
  • MONTH
  • WEEK

Upturn Advisory Summary

10/15/2025: IRWD (1-star) is currently NOT-A-BUY. Pass it for now.

Upturn Star Rating

rating

Not Recommended Performance

These Stocks/ETFs, based on Upturn Advisory, consistently fall short of market performance, signaling caution before investing.

Number of Analysts

rating

4 Analysts rated it

Very few follow this stock; limited insights, higher-risk early investing.

1 Year Target Price $0.95

1 Year Target Price $0.95

Analysts Price Target For last 52 week
$0.95 Target price
52w Low $0.53
Current$1.61
52w High $5.13

Analysis of Past Performance

Type Stock
Historic Profit -57.25%
Avg. Invested days 23
Today’s Advisory PASS
Upturn Star Rating upturn star rating icon
Upturn Advisory Performance Upturn Advisory Performance 1.0
Stock Returns Performance Upturn Returns Performance 1.0
Upturn Profits based on simulation Profits based on simulation
Upturn Profits based on simulation Last Close 10/15/2025

Key Highlights

Company Size Small-Cap Stock
Market Capitalization 251.77M USD
Price to earnings Ratio -
1Y Target Price 0.95
Price to earnings Ratio -
1Y Target Price 0.95
Volume (30-day avg) 4
Beta 0.3
52 Weeks Range 0.53 - 5.13
Updated Date 10/16/2025
52 Weeks Range 0.53 - 5.13
Updated Date 10/16/2025
Dividends yield (FY) -
Basic EPS (TTM) -0.05

Analyzing Revenue: Products, Geography and Growth

Revenue by Products

Product revenue - Year on Year

Revenue by Geography

Geography revenue - Year on Year

Earnings Date

Report Date -
When -
Estimate -
Actual -

Profitability

Profit Margin -2.56%
Operating Margin (TTM) 52.88%

Management Effectiveness

Return on Assets (TTM) 15.53%
Return on Equity (TTM) -574.72%

Valuation

Trailing PE -
Forward PE 12.33
Enterprise Value 767335949
Price to Sales(TTM) 0.82
Enterprise Value 767335949
Price to Sales(TTM) 0.82
Enterprise Value to Revenue 2.49
Enterprise Value to EBITDA 9.64
Shares Outstanding 162434130
Shares Floating 118078242
Shares Outstanding 162434130
Shares Floating 118078242
Percent Insiders 2.67
Percent Institutions 97.42

ai summary icon Upturn AI SWOT

Ironwood Pharmaceuticals Inc

stock logo

Company Overview

overview logo History and Background

Ironwood Pharmaceuticals, Inc. was founded in 1998. It is a biopharmaceutical company focused on developing and commercializing innovative medicines to treat gastrointestinal (GI) diseases and address unmet needs.

business area logo Core Business Areas

  • GI Franchise: Focused on developing and commercializing treatments for gastrointestinal diseases, particularly irritable bowel syndrome with constipation (IBS-C).
  • Research and Development: Investing in research to expand pipeline of GI-focused therapies.

leadership logo Leadership and Structure

Tom McCourt is the current CEO. The company has a typical corporate structure with functional departments like R&D, Commercial, Finance, and Operations.

Top Products and Market Share

overview logo Key Offerings

  • Linzess/Constella (linaclotide): A guanylate cyclase-C (GC-C) agonist used to treat IBS-C and chronic idiopathic constipation (CIC). Ironwood collaborates with AbbVie (ABBV) in the US and Astellas Pharma globally, excluding China. Linzess holds a significant market share in the branded IBS-C/CIC market. Competitors include Trulance (plecanatide) by Salix Pharmaceuticals, a Bausch Health company (BHC), and generics.

Market Dynamics

industry overview logo Industry Overview

The pharmaceutical industry is driven by innovation, regulatory approvals, and market access. The GI therapeutics market is competitive, with both branded and generic options.

Positioning

Ironwood is a key player in the GI space, focusing on IBS-C and CIC. Its competitive advantage lies in its established product (Linzess) and partnerships with major pharmaceutical companies.

Total Addressable Market (TAM)

The global IBS market is estimated to be over $8 billion. Ironwood, through Linzess, targets a significant portion of the IBS-C and CIC market.

Upturn SWOT Analysis

Strengths

  • Established product (Linzess)
  • Partnership with AbbVie
  • Focus on GI therapeutics
  • Experienced management team

Weaknesses

  • Reliance on a single key product
  • Competition from other IBS-C/CIC treatments
  • Patent expiration risks
  • Dependence on partneru2019s success for Linzess commercialization

Opportunities

  • Expansion of Linzess indications
  • Development of new GI therapies
  • Strategic acquisitions
  • Geographic expansion

Threats

  • Generic competition
  • Clinical trial failures
  • Regulatory changes
  • Pricing pressures

Competitors and Market Share

competitor logo Key Competitors

  • BHC
  • ABBV

Competitive Landscape

Ironwood's key advantage is its established presence in the IBS-C/CIC market. It faces competition from other pharmaceutical companies with alternative treatments.

Growth Trajectory and Initiatives

Historical Growth: Growth has been tied to the increasing adoption of Linzess and the effectiveness of its marketing efforts. Has been relatively stable over time.

Future Projections: Future growth is expected to come from continued Linzess sales and potential new product launches. Analyst estimates vary based on market conditions and competitive pressures.

Recent Initiatives: Ironwood has focused on optimizing its commercial operations and advancing its pipeline of GI therapies.

Summary

Ironwood Pharmaceuticals is a mid-sized biopharmaceutical company heavily reliant on Linzess for revenue. Its partnership with AbbVie is crucial for its US market success. Future growth hinges on extending Linzess's market presence and developing new products. Regulatory pressures and competition pose challenges.

Peer Comparison

Sources and Disclaimers

Data Sources:

  • SEC Filings
  • Company Investor Relations
  • Analyst Reports
  • Market Research Reports

Disclaimers:

This analysis is for informational purposes only and should not be considered investment advice. Market conditions can change rapidly, affecting the accuracy of the data and projections.

Upturn AI Summarization AI Summarization is directionally correct and might not be accurate.

Upturn AI Summarization Summarized information shown could be a few years old and not current.

Upturn AI Summarization Fundamental Rating based on AI could be based on old data.

Upturn AI Summarization AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.

About Ironwood Pharmaceuticals Inc

Exchange NASDAQ
Headquaters Boston, MA, United States
IPO Launch date 2010-02-03
CEO & Director Mr. Thomas A. McCourt
Sector Healthcare
Industry Drug Manufacturers - Specialty & Generic
Full time employees 253
Full time employees 253

Ironwood Pharmaceuticals, Inc., a biotechnology company, focuses on the development and commercialization of therapies for gastrointestinal (GI) and rare diseases in the United States and internationally. It markets linaclotide, a guanylate cyclase type-C (GC-C) agonist for the treatment of adults suffering from irritable bowel syndrome with constipation or chronic idiopathic constipation, as well as for pediatric patients suffering from functional constipation under the LINZESS and CONSTELLA names. The company is also developing IW-3300, a GC-C agonist for the treatment of visceral pain conditions, including interstitial cystitis/bladder pain syndrome and endometriosis; and Apraglutide, a long-acting synthetic peptide analog of glucagon-like peptide-2 for short bowel syndrome patients dependent on parenteral support, as well as for acute graft versus host disease. It has strategic partnerships with AbbVie Inc., AstraZeneca AB, and Astellas Pharma Inc. for the development and commercialization of linaclotide. The company was formerly known as Microbia, Inc. and changed its name to Ironwood Pharmaceuticals, Inc. in April 2008. Ironwood Pharmaceuticals, Inc. was incorporated in 1998 and is headquartered in Boston, Massachusetts.